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The map label for this gene is ddc [H]

Identifier: 162147675

GI number: 162147675

Start: 1927295

End: 1928737

Strand: Direct

Name: ddc [H]

Synonym: GDI_1891

Alternate gene names: 162147675

Gene position: 1927295-1928737 (Clockwise)

Preceding gene: 162147673

Following gene: 162147679

Centisome position: 48.86

GC content: 69.85

Gene sequence:

>1443_bases
ATGACCGGACTGGACCCCGACAACTGGGACGACCTGCGGAGCCTGGGGCACCGCATGGTGGATGACATGATCGACCGGCT
GGCGACCCTGCGTGACGGGCCGGTCTGGCGCCCGATGCCGCCGGAAATCCGTACCGCCCTGCATACCGACCTGCCGGCCG
CCCCGACGCCGCCCGAAGCGCTGTACGACCGGTTTCGCGACCAGATCGCCCCCTATGCCACCGGCAACACCCATCCGGGC
TTCATGGGCTGGGTCCATGGCGGCGGGACGGGGGTGGGGATGCTGGCCGAACTGCTGGCCGGCGGGCTGAACGCCAATTG
CGGCGGCCGCGACCACGCGCCGGTCGAAATCGAGCGTACGGTCATCGGCTGGGCCGCCGAGATCATGGGCTTTCCCGCCG
ATGCGACGGGCGTGCTGGTCACCGGGTCCTCGATGGCCAACATGATCGCCGTCATCACCGCCAGCCGCGCGGTCGCGGAC
GGCATCACCCTGCGGCAGCGCGGCGTCGGCGGCCGGCAACTGGTCGGCTATGCCGCCGCCACCGCCCATGGCTGCATCGC
CCGCGCCTTCGACCTGGCGGGACTGGGGACCGACGCGCTGCGCATCATCCCCGTGGATTCGACCCATCGCATGGATATCC
AGGCCCTGCGCGCCGCCGTGGAATCCGACCGGCAGCAGGGTTTCGAGCCGTTCATCGTCATCGGCACCGCCGGGACGGTC
GATACCGGTTCGATCGACGACCTGGGCGCCATCGCCGACATCGCGGCGCAAGAGGACATCTGGTTCCACGTCGACGGCGC
CTTCGGCGCGCTGGCCATGCTGTCCCGCACGCTGCGCCCGCATCTGCGCGGCCTGGATCGCGCGGACAGCCTGGCATTCG
ATTTTCACAAATGGGCCCAGGTGCCGTACGATGCCGGTTGCATCCTGGTGCGCGAACCCGGGCGCCAGGCGGCGGCCTTC
GCGCAATCGCTGGCCTATCTGTCGCGCGAGGACCGGGGCCTGGCGGGCAACGCGCCCTGGTTCTGCGACCTGGGGCCGGA
CCTGTCGCGCGGCTTTCGTGCCCTGAAGGTCTGGATGACGCTGGGCACCTACGGCACCGTCCGCCTGGGGCAGATGGTCG
ACGAATGCTGCGCCGTCGCGGCCCATCTGGCCCGGCGCGTGGATCGCGAGCCGCTGCTGGAACGCCTGGCACCGGTCGGG
CTGAACATCGTCTGCTTTCGCGTGCGCGTTCCGGACGTGGAGTTGGACTGGCTGAACGGCGAACTGGTCAAGGACCTGCA
CGAATCCGGCATCGCCGCGCCCTCCACGACGATGGTGGGTGGGGTGAAGGCCATTCGCGCCGCGATCGTCAATCACCGCA
CCGTGGCGGCGGATGTCGACCTTATGGTCGATGCGGTGCTGCGGCTGGCCCAGGAAAGGCAAGGGCTCGGCCAAAGGGCC
TAG

Upstream 100 bases:

>100_bases
CCGATAGGGGCACATATAGGGATATCGTCGATTATTGGACAGAGCCGGCCCGACAATGCCAGTCGGGGCCGCTAGGATGT
AACAGGAAACGAAGCCGCTT

Downstream 100 bases:

>100_bases
CCCTTTGGAAACCCTATTGTTTCAGGCGATTCGGCGGCGACCCGCGACAGCGACCTTTTCATCGAAAAGTTCGGAGAGCT
TCTGCATCATCGTGCCGCCC

Product: tyrosine decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTGLDPDNWDDLRSLGHRMVDDMIDRLATLRDGPVWRPMPPEIRTALHTDLPAAPTPPEALYDRFRDQIAPYATGNTHPG
FMGWVHGGGTGVGMLAELLAGGLNANCGGRDHAPVEIERTVIGWAAEIMGFPADATGVLVTGSSMANMIAVITASRAVAD
GITLRQRGVGGRQLVGYAAATAHGCIARAFDLAGLGTDALRIIPVDSTHRMDIQALRAAVESDRQQGFEPFIVIGTAGTV
DTGSIDDLGAIADIAAQEDIWFHVDGAFGALAMLSRTLRPHLRGLDRADSLAFDFHKWAQVPYDAGCILVREPGRQAAAF
AQSLAYLSREDRGLAGNAPWFCDLGPDLSRGFRALKVWMTLGTYGTVRLGQMVDECCAVAAHLARRVDREPLLERLAPVG
LNIVCFRVRVPDVELDWLNGELVKDLHESGIAAPSTTMVGGVKAIRAAIVNHRTVAADVDLMVDAVLRLAQERQGLGQRA

Sequences:

>Translated_480_residues
MTGLDPDNWDDLRSLGHRMVDDMIDRLATLRDGPVWRPMPPEIRTALHTDLPAAPTPPEALYDRFRDQIAPYATGNTHPG
FMGWVHGGGTGVGMLAELLAGGLNANCGGRDHAPVEIERTVIGWAAEIMGFPADATGVLVTGSSMANMIAVITASRAVAD
GITLRQRGVGGRQLVGYAAATAHGCIARAFDLAGLGTDALRIIPVDSTHRMDIQALRAAVESDRQQGFEPFIVIGTAGTV
DTGSIDDLGAIADIAAQEDIWFHVDGAFGALAMLSRTLRPHLRGLDRADSLAFDFHKWAQVPYDAGCILVREPGRQAAAF
AQSLAYLSREDRGLAGNAPWFCDLGPDLSRGFRALKVWMTLGTYGTVRLGQMVDECCAVAAHLARRVDREPLLERLAPVG
LNIVCFRVRVPDVELDWLNGELVKDLHESGIAAPSTTMVGGVKAIRAAIVNHRTVAADVDLMVDAVLRLAQERQGLGQRA
>Mature_479_residues
TGLDPDNWDDLRSLGHRMVDDMIDRLATLRDGPVWRPMPPEIRTALHTDLPAAPTPPEALYDRFRDQIAPYATGNTHPGF
MGWVHGGGTGVGMLAELLAGGLNANCGGRDHAPVEIERTVIGWAAEIMGFPADATGVLVTGSSMANMIAVITASRAVADG
ITLRQRGVGGRQLVGYAAATAHGCIARAFDLAGLGTDALRIIPVDSTHRMDIQALRAAVESDRQQGFEPFIVIGTAGTVD
TGSIDDLGAIADIAAQEDIWFHVDGAFGALAMLSRTLRPHLRGLDRADSLAFDFHKWAQVPYDAGCILVREPGRQAAAFA
QSLAYLSREDRGLAGNAPWFCDLGPDLSRGFRALKVWMTLGTYGTVRLGQMVDECCAVAAHLARRVDREPLLERLAPVGL
NIVCFRVRVPDVELDWLNGELVKDLHESGIAAPSTTMVGGVKAIRAAIVNHRTVAADVDLMVDAVLRLAQERQGLGQRA

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=452, Percent_Identity=25.2212389380531, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4503281, Length=414, Percent_Identity=28.9855072463768, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI132814448, Length=414, Percent_Identity=28.9855072463768, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI92110055, Length=468, Percent_Identity=24.7863247863248, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI197276620, Length=459, Percent_Identity=26.1437908496732, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4503875, Length=459, Percent_Identity=26.1437908496732, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI58331246, Length=455, Percent_Identity=26.5934065934066, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI194294551, Length=497, Percent_Identity=25.1509054325956, Blast_Score=123, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17534819, Length=484, Percent_Identity=25.4132231404959, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17534817, Length=484, Percent_Identity=25.4132231404959, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71981211, Length=522, Percent_Identity=21.6475095785441, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17555682, Length=491, Percent_Identity=24.4399185336049, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71981217, Length=526, Percent_Identity=22.6235741444867, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71993062, Length=417, Percent_Identity=25.6594724220624, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71993058, Length=397, Percent_Identity=25.1889168765743, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI133931025, Length=470, Percent_Identity=22.5531914893617, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551992, Length=505, Percent_Identity=22.7722772277228, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28573972, Length=470, Percent_Identity=27.4468085106383, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24652373, Length=470, Percent_Identity=28.5106382978723, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24586044, Length=481, Percent_Identity=26.6112266112266, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24585135, Length=491, Percent_Identity=26.6802443991853, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24585139, Length=484, Percent_Identity=25.4132231404959, Blast_Score=148, Evalue=9e-36,
Organism=Drosophila melanogaster, GI221476190, Length=486, Percent_Identity=25.3086419753086, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24585143, Length=486, Percent_Identity=25.3086419753086, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17136190, Length=488, Percent_Identity=26.844262295082, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356415, Length=394, Percent_Identity=25.6345177664975, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24657193, Length=463, Percent_Identity=26.5658747300216, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24657185, Length=463, Percent_Identity=26.5658747300216, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24657188, Length=463, Percent_Identity=26.5658747300216, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136594, Length=457, Percent_Identity=24.0700218818381, Blast_Score=122, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 51466; Mature: 51335

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLDPDNWDDLRSLGHRMVDDMIDRLATLRDGPVWRPMPPEIRTALHTDLPAAPTPPEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCHHH
LYDRFRDQIAPYATGNTHPGFMGWVHGGGTGVGMLAELLAGGLNANCGGRDHAPVEIERT
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEHH
VIGWAAEIMGFPADATGVLVTGSSMANMIAVITASRAVADGITLRQRGVGGRQLVGYAAA
HHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHH
TAHGCIARAFDLAGLGTDALRIIPVDSTHRMDIQALRAAVESDRQQGFEPFIVIGTAGTV
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DTGSIDDLGAIADIAAQEDIWFHVDGAFGALAMLSRTLRPHLRGLDRADSLAFDFHKWAQ
CCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
VPYDAGCILVREPGRQAAAFAQSLAYLSREDRGLAGNAPWFCDLGPDLSRGFRALKVWMT
CCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
LGTYGTVRLGQMVDECCAVAAHLARRVDREPLLERLAPVGLNIVCFRVRVPDVELDWLNG
HCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCEEEECCCC
ELVKDLHESGIAAPSTTMVGGVKAIRAAIVNHRTVAADVDLMVDAVLRLAQERQGLGQRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TGLDPDNWDDLRSLGHRMVDDMIDRLATLRDGPVWRPMPPEIRTALHTDLPAAPTPPEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCHHH
LYDRFRDQIAPYATGNTHPGFMGWVHGGGTGVGMLAELLAGGLNANCGGRDHAPVEIERT
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEHH
VIGWAAEIMGFPADATGVLVTGSSMANMIAVITASRAVADGITLRQRGVGGRQLVGYAAA
HHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHH
TAHGCIARAFDLAGLGTDALRIIPVDSTHRMDIQALRAAVESDRQQGFEPFIVIGTAGTV
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DTGSIDDLGAIADIAAQEDIWFHVDGAFGALAMLSRTLRPHLRGLDRADSLAFDFHKWAQ
CCCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
VPYDAGCILVREPGRQAAAFAQSLAYLSREDRGLAGNAPWFCDLGPDLSRGFRALKVWMT
CCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
LGTYGTVRLGQMVDECCAVAAHLARRVDREPLLERLAPVGLNIVCFRVRVPDVELDWLNG
HCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCEEEECCCC
ELVKDLHESGIAAPSTTMVGGVKAIRAAIVNHRTVAADVDLMVDAVLRLAQERQGLGQRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]