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The map label for this gene is kdsB [H]

Identifier: 162147661

GI number: 162147661

Start: 1912043

End: 1912828

Strand: Direct

Name: kdsB [H]

Synonym: GDI_1877

Alternate gene names: 162147661

Gene position: 1912043-1912828 (Clockwise)

Preceding gene: 162147657

Following gene: 162147662

Centisome position: 48.48

GC content: 72.52

Gene sequence:

>786_bases
GTGCCCGCACCGGCATTTTTCCATAAGGCCTTCGCTTTCCGCATGAACCCGATCGTCGTCATTCCCGCCCGCATGGCCTC
TACACGGCTGCCGGGCAAGCCGCTGGCCATGATCGGCAAGCTGCCCATGATCCTGCATGTCCTGGCGCGGGCCCGGGCGG
CCGATATCGGGCCCGTCATCGTCGCGGTGGCGGAAACCGAACTGGCGCGCGTTGTCGAGGACGCGGGCGGCACGGCGGTC
CTGACCGACCCGGCGCTGCCCTCGGGGTCCGACCGGGTGTGGCAGGCGGTGCGGGCGGCCGATCCGGCCGGGCGGCACGA
TGTCGTCGTGAACCTGCAGGGCGACCTGCCCGGGGTGGCGCCGCCGACGCTGGCCGCGTCCCTGCTGCCGCTGGCCGATC
CCGCGACCGATATCGGCACGCTGGTCTGCCCGGTGGCCGACGCCGGGGAGGCCGCGCGCGATTCGGTGGTGAAGGTCGCC
TGCGCCTTTGCCGACGACGATGCGCGAACGGTGGCCCGGGCGCTGTATTTCTCGCGCGCCGCCGTGCCGTGGGGGGCGGG
CGCGCTGTGGCACCATGTCGGGATCTATGCCTATCGTCGCGCGGCGCTGGCCCGCTTCGTCAGCCTGCCGGAAGCGGCGC
TGGAGCGGCGGGAGAGGCTGGAACAGCTCAGGGCCCTGGAGGCTGGAATGACGATCGGGTGCTGCCGCATCGGAACCGCG
CCGTTCGGCGTCGATACCCCCGACGACCTGGACCGCGCGCGCCGTGTCATGGCGGAGGCGGCATGA

Upstream 100 bases:

>100_bases
CCTATGAATTTCGGAGGCAGGACACTAGACTGCGGGCCGCCTTGTGTGAAGCATTGCCGGATCGTTCCGTCAGGATCGCA
TCCCATGTCTGCGAGGTCTC

Downstream 100 bases:

>100_bases
GCGGCGTCATCGCCTTCCAGGGGCGGCCCGGGGCCTATTCCGACCTGGCCTGCCGGCAGGCCTATCCGGGATGGACCACC
CTGCCGTGCGAAACCTTCGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPAPAFFHKAFAFRMNPIVVIPARMASTRLPGKPLAMIGKLPMILHVLARARAADIGPVIVAVAETELARVVEDAGGTAV
LTDPALPSGSDRVWQAVRAADPAGRHDVVVNLQGDLPGVAPPTLAASLLPLADPATDIGTLVCPVADAGEAARDSVVKVA
CAFADDDARTVARALYFSRAAVPWGAGALWHHVGIYAYRRAALARFVSLPEAALERRERLEQLRALEAGMTIGCCRIGTA
PFGVDTPDDLDRARRVMAEAA

Sequences:

>Translated_261_residues
MPAPAFFHKAFAFRMNPIVVIPARMASTRLPGKPLAMIGKLPMILHVLARARAADIGPVIVAVAETELARVVEDAGGTAV
LTDPALPSGSDRVWQAVRAADPAGRHDVVVNLQGDLPGVAPPTLAASLLPLADPATDIGTLVCPVADAGEAARDSVVKVA
CAFADDDARTVARALYFSRAAVPWGAGALWHHVGIYAYRRAALARFVSLPEAALERRERLEQLRALEAGMTIGCCRIGTA
PFGVDTPDDLDRARRVMAEAA
>Mature_260_residues
PAPAFFHKAFAFRMNPIVVIPARMASTRLPGKPLAMIGKLPMILHVLARARAADIGPVIVAVAETELARVVEDAGGTAVL
TDPALPSGSDRVWQAVRAADPAGRHDVVVNLQGDLPGVAPPTLAASLLPLADPATDIGTLVCPVADAGEAARDSVVKVAC
AFADDDARTVARALYFSRAAVPWGAGALWHHVGIYAYRRAALARFVSLPEAALERRERLEQLRALEAGMTIGCCRIGTAP
FGVDTPDDLDRARRVMAEAA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=255, Percent_Identity=39.2156862745098, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27477; Mature: 27346

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPAFFHKAFAFRMNPIVVIPARMASTRLPGKPLAMIGKLPMILHVLARARAADIGPVI
CCCHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
VAVAETELARVVEDAGGTAVLTDPALPSGSDRVWQAVRAADPAGRHDVVVNLQGDLPGVA
EEEHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
PPTLAASLLPLADPATDIGTLVCPVADAGEAARDSVVKVACAFADDDARTVARALYFSRA
CHHHHHHHHCCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHECCCCHHHHHHHHHHHHHC
AVPWGAGALWHHVGIYAYRRAALARFVSLPEAALERRERLEQLRALEAGMTIGCCRIGTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
PFGVDTPDDLDRARRVMAEAA
CCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAPAFFHKAFAFRMNPIVVIPARMASTRLPGKPLAMIGKLPMILHVLARARAADIGPVI
CCHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
VAVAETELARVVEDAGGTAVLTDPALPSGSDRVWQAVRAADPAGRHDVVVNLQGDLPGVA
EEEHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
PPTLAASLLPLADPATDIGTLVCPVADAGEAARDSVVKVACAFADDDARTVARALYFSRA
CHHHHHHHHCCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHECCCCHHHHHHHHHHHHHC
AVPWGAGALWHHVGIYAYRRAALARFVSLPEAALERRERLEQLRALEAGMTIGCCRIGTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
PFGVDTPDDLDRARRVMAEAA
CCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA