Click here to switch to the map view.

The map label for this gene is prpE [H]

Identifier: 162147617

GI number: 162147617

Start: 1864823

End: 1865677

Strand: Reverse

Name: prpE [H]

Synonym: GDI_1833

Alternate gene names: 162147617

Gene position: 1865677-1864823 (Counterclockwise)

Preceding gene: 162147618

Following gene: 162147616

Centisome position: 47.3

GC content: 70.41

Gene sequence:

>855_bases
ATGCCATTGGAACGTCCCCACCCATCCGGCCCAGCATGGACACCGCCCATCGCCGATGCGCGGGCGCCGGACGGGCCGTA
CCTGCCCCCGGACGGCCATGCGGACGACCATGCCGCCCTCGATTCCGTCACGGACGTCCCGGCGTTTTATGACCCGGTCG
CGGTGGAACGGCTGATCGACGGGCGGCCGATTCGCGTCGTGGGGGACGTCCATGGGGACCTGCGGGCGTTCGAGCACGCG
GTGGCCACCGACCGGTTCGTCATCCAGTTGGGCGACCTGGTCGATCACGGGCCGGACAGCGCCGGCACGTTCCGCCTGAT
GCAGCGCCTGCTGGATGACGGGCGCGGCCTGTTCATCCTGGGCAACCACGACCGCAAGCTGGCCCGCGCCCTGGCGGGGC
GGAAGATGCGCCAGGACGCCCCGCTGATCCAGACCATGCGCCAGTTCCAGGCACCGGAGAACGAGGACGTCCGCACCCGG
GCCTGGCAGGACATCGCCCATGCCCCGCCCTGGATCGTGCTGGGCCGGCGCATCTTCGTGCATGGCGGCTTCCATTCGCG
GATGCTGAACGAACCGCCGCCGCCGGGCCTGGGCACGGTGACCCCGCTGCTGTCCCGCGCGCTGTTCGGCGAGACCACCG
GGCGCATGCAGAAGGACGGCTATCCGGAACGGCGCCTGAACTGGATCGACCATATTCCGCCCGGCTATACCGTCTATTGC
GGCCATGACCGCCGTTCGACCGACGGGCGGCCCTGGATCAGGGTCGGCCGGGCCGGCGGCACGTCCGTCTTCACCGACAC
CGGGGCGGGAAAAGGTGGCCATCTGGCCTGGATCGACCTGCCCGACGACGCATGA

Upstream 100 bases:

>100_bases
AATTCAGGAAACCCGGCGCCAAGGGGCCGGTGCCCATGGCGAAGTCCGTACCGCATCCCCATATCCAGAAGCTGACAACT
TCATTCCATGACCCACGGAC

Downstream 100 bases:

>100_bases
AACCCTGTATAACGGTCGCGACCGACAGACAGGAGCATGACGTGAACGATATGACGGCCATCGACAGGACCCTTGCGACG
CCGGAGGCGCAGGCGACCCT

Product: phosphoesterases

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPLERPHPSGPAWTPPIADARAPDGPYLPPDGHADDHAALDSVTDVPAFYDPVAVERLIDGRPIRVVGDVHGDLRAFEHA
VATDRFVIQLGDLVDHGPDSAGTFRLMQRLLDDGRGLFILGNHDRKLARALAGRKMRQDAPLIQTMRQFQAPENEDVRTR
AWQDIAHAPPWIVLGRRIFVHGGFHSRMLNEPPPPGLGTVTPLLSRALFGETTGRMQKDGYPERRLNWIDHIPPGYTVYC
GHDRRSTDGRPWIRVGRAGGTSVFTDTGAGKGGHLAWIDLPDDA

Sequences:

>Translated_284_residues
MPLERPHPSGPAWTPPIADARAPDGPYLPPDGHADDHAALDSVTDVPAFYDPVAVERLIDGRPIRVVGDVHGDLRAFEHA
VATDRFVIQLGDLVDHGPDSAGTFRLMQRLLDDGRGLFILGNHDRKLARALAGRKMRQDAPLIQTMRQFQAPENEDVRTR
AWQDIAHAPPWIVLGRRIFVHGGFHSRMLNEPPPPGLGTVTPLLSRALFGETTGRMQKDGYPERRLNWIDHIPPGYTVYC
GHDRRSTDGRPWIRVGRAGGTSVFTDTGAGKGGHLAWIDLPDDA
>Mature_283_residues
PLERPHPSGPAWTPPIADARAPDGPYLPPDGHADDHAALDSVTDVPAFYDPVAVERLIDGRPIRVVGDVHGDLRAFEHAV
ATDRFVIQLGDLVDHGPDSAGTFRLMQRLLDDGRGLFILGNHDRKLARALAGRKMRQDAPLIQTMRQFQAPENEDVRTRA
WQDIAHAPPWIVLGRRIFVHGGFHSRMLNEPPPPGLGTVTPLLSRALFGETTGRMQKDGYPERRLNWIDHIPPGYTVYCG
HDRRSTDGRPWIRVGRAGGTSVFTDTGAGKGGHLAWIDLPDDA

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 31325; Mature: 31194

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLERPHPSGPAWTPPIADARAPDGPYLPPDGHADDHAALDSVTDVPAFYDPVAVERLID
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCHHHHHHHHC
GRPIRVVGDVHGDLRAFEHAVATDRFVIQLGDLVDHGPDSAGTFRLMQRLLDDGRGLFIL
CCCEEEEECCCHHHHHHHHHHHCCHHEEEECHHHHCCCCCHHHHHHHHHHHHCCCCEEEE
GNHDRKLARALAGRKMRQDAPLIQTMRQFQAPENEDVRTRAWQDIAHAPPWIVLGRRIFV
ECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCEEEE
HGGFHSRMLNEPPPPGLGTVTPLLSRALFGETTGRMQKDGYPERRLNWIDHIPPGYTVYC
ECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEE
GHDRRSTDGRPWIRVGRAGGTSVFTDTGAGKGGHLAWIDLPDDA
CCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
PLERPHPSGPAWTPPIADARAPDGPYLPPDGHADDHAALDSVTDVPAFYDPVAVERLID
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCHHHHHHHHC
GRPIRVVGDVHGDLRAFEHAVATDRFVIQLGDLVDHGPDSAGTFRLMQRLLDDGRGLFIL
CCCEEEEECCCHHHHHHHHHHHCCHHEEEECHHHHCCCCCHHHHHHHHHHHHCCCCEEEE
GNHDRKLARALAGRKMRQDAPLIQTMRQFQAPENEDVRTRAWQDIAHAPPWIVLGRRIFV
ECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCEEEE
HGGFHSRMLNEPPPPGLGTVTPLLSRALFGETTGRMQKDGYPERRLNWIDHIPPGYTVYC
ECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEE
GHDRRSTDGRPWIRVGRAGGTSVFTDTGAGKGGHLAWIDLPDDA
CCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA