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The map label for this gene is iorB [H]

Identifier: 162147570

GI number: 162147570

Start: 1815768

End: 1817915

Strand: Direct

Name: iorB [H]

Synonym: GDI_1786

Alternate gene names: 162147570

Gene position: 1815768-1817915 (Clockwise)

Preceding gene: 162147569

Following gene: 162147571

Centisome position: 46.04

GC content: 70.11

Gene sequence:

>2148_bases
ATGGGCCGCACGATGCTGTCGCGCCGCCAGGCCCTGGCGGGCACGGGCGGCCTGCTGCTGGCGGCCATGCTGCCGCGCGG
GGCGGCCCGGGCCGCGACCCGGATCGTCGAGGACCAGACCGGCCCGTTCGCGCCCAACGCCTTCGTACGAATCGCACCCG
ATGGGGCCATCACGCTGATCCTGCCCAATGTCGAAATGGGGCAGGGGATCTATACCGGCGAGGCGATGCTGATCGCCGAG
GAACTGGATATCGGGCTGGAACAGATCCAGATCGAGGCCGCCCCCCCGGACGACGCCTACGTGACCAGGGAACTGGGCAC
GCAGGCAACCGGCGGATCGACCTCGACGATCGCGACGTGGAAGAGCCTGCGAGAAGCCGGGGCGGTGGCGCGGACGCTTC
TGGTCCAGGCGGCGGCGGCCCAGTGGTCGGTCGATCCCGCATCCTGCACCACCGGGGGCGGCATGGTCCGGCACGAGGCG
ACGGGGCGCAGCCTGGCCTATGGCGAACTCGCAACCGCCGCCGCCGCCCTGCCGGTGCCGGCCGCACCCGTGACGCTGCG
AGATCCGTCTTCCTTTCGCCTGGTCGGGCGATCCCAGCACCGTCTGGACGCGCCGGCCAAGGTCGCGGGAACCGCGACGT
TCGGCATCGACGTGCAGGTACCGGGCATGCGCATCGGCACCGTGGCGGCCTGCCCGGTCATGGGCGGCGTGCTGGCGCAT
GTGGATGACAGCGCGGCGCGGCAGGTCCCCGGCGTGCGGGACGTCCTGACGATCGGCAATGCGGTCTGCGTGGTCGGGAA
CCATTTCTGGGCAGCGCGCAAGGGGCTGGATGCCCTGGTGATCACATGGGACGAAGGCGTCAACGCGGCGGTTTCCACCG
ATACGATCTATCGCCAGTTGCACGAGGCGCTGGACGGTCCGGCCATTACCGCCCACGCCAAGGGCGACGCCAGGGCGGCG
ATCGCAGGTGCCACGACGCGGGTCGAGGCCGTGTACCAGCAGCCCCTGCTGGCCCACGCGCCGATGGAGCCGATCAACTG
CACCGTGCAGGTCACGCCCGAACGCTGCGACATCTGGGTGGGTTCGCAGGTACCTATGCGCGCGCGCGACGCGGCGGCGG
ACATCACCGGGCTGGGCAAGGACCGGGTCCATGTCCACAACCAGTATATCGGCGGCGGCTTCGGCCGGCGGCTGGAACAT
GAATATGTCATCCAGGCGGTGCAGTTCGCCCGTCAGGTCGCCTATCCGCTCAAGATCGTCTGGACGCGCGAGGAAGACCT
GACGCTGGACCGCTTTCGTCCGGCCTATGTCGATCGCCTGGTCGGCGGCCTGGACCGGAAGGGAAACCTGGTCGGACTGT
CGCACCGGATCGTCGGCCCCGCCGTGGTCGCCCGCTGGGCGCCCGAGGCGCTGCTGCCCAACGGGGTGGACGACGACCTG
CTGGCCGCGACGGTCGAGACCCCGTACGCCATTCCCGCGATGTTCCTGGATTACGCCCGGCGCGAGGCCCCGGGCGTGGT
CACCGCGTGGTGGCGCGGGGTAGGGGGCACGCGGGGCGTCTTCGTGGTCGAAAGCTTCATCGACGAACTGGCGGCGCGTG
CCGGGAAGGATGCGGTGGCGTTTCGCCGCCAGATGACCGGGGGCAATCCCCGCGCCCGGGCGGTACTGGACCTGGCCGCC
GAAAAGGCGAGCTGGGGCGAGCCGCTGCCCAAGCATGTCGGCCGCGGGATTGCCCTGCAATACGTGTTCGGCTCCTACCT
GGCCACGGTGATGGAGGTCGACATGTCCGACATGGACACGGTACGCGTCCTGCGCGCCGTGGTGGCCGTGGATTGCGGCC
GGATGGTCAATCCCGACCAGGTCGTATCCCAGATCGAGGGCGGCCTGATCTTCGGCATCAGCGCCGCCCTGTTCAACGAG
GTGACGCTGCGCGACGGCCGCGTGCAGGAGACGAATTTCCATTCCTACCGGGTCCTGCGCATGAACGAATCCCCCATGAT
CGAGGTGCATCTGGTGAACAGCACCGAGGACCCGGGCGGCATCGGCGAAACCGGCACGGCGGCGGCGGCGGCGGCGCTGG
CCAACGCCATGGCCGCCGCCACCGGCCGGCGCTATCGCAGGCTGCCCCTGACGGGACCCCAGGCATGA

Upstream 100 bases:

>100_bases
CCGACGAGGAGATCGAGCAGGCGATGGCCGGCAATATCTGTCGCTGCGGCACCTATCGCCGGATTCGCGCGGCTATCCGC
AACGCCGCCGGGGCTGCGTG

Downstream 100 bases:

>100_bases
GGGCGGTGCGTGCCGTCCTGGCGCTGGTGACGCTGGGCGTGGCCACGGGCGGCGTGGCCCAGGCCCAGGACCAGGCCCAA
GTTCAGGCCCAGGATTCGGA

Product: isoquinoline 1-oxidoreductase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MGRTMLSRRQALAGTGGLLLAAMLPRGAARAATRIVEDQTGPFAPNAFVRIAPDGAITLILPNVEMGQGIYTGEAMLIAE
ELDIGLEQIQIEAAPPDDAYVTRELGTQATGGSTSTIATWKSLREAGAVARTLLVQAAAAQWSVDPASCTTGGGMVRHEA
TGRSLAYGELATAAAALPVPAAPVTLRDPSSFRLVGRSQHRLDAPAKVAGTATFGIDVQVPGMRIGTVAACPVMGGVLAH
VDDSAARQVPGVRDVLTIGNAVCVVGNHFWAARKGLDALVITWDEGVNAAVSTDTIYRQLHEALDGPAITAHAKGDARAA
IAGATTRVEAVYQQPLLAHAPMEPINCTVQVTPERCDIWVGSQVPMRARDAAADITGLGKDRVHVHNQYIGGGFGRRLEH
EYVIQAVQFARQVAYPLKIVWTREEDLTLDRFRPAYVDRLVGGLDRKGNLVGLSHRIVGPAVVARWAPEALLPNGVDDDL
LAATVETPYAIPAMFLDYARREAPGVVTAWWRGVGGTRGVFVVESFIDELAARAGKDAVAFRRQMTGGNPRARAVLDLAA
EKASWGEPLPKHVGRGIALQYVFGSYLATVMEVDMSDMDTVRVLRAVVAVDCGRMVNPDQVVSQIEGGLIFGISAALFNE
VTLRDGRVQETNFHSYRVLRMNESPMIEVHLVNSTEDPGGIGETGTAAAAAALANAMAAATGRRYRRLPLTGPQA

Sequences:

>Translated_715_residues
MGRTMLSRRQALAGTGGLLLAAMLPRGAARAATRIVEDQTGPFAPNAFVRIAPDGAITLILPNVEMGQGIYTGEAMLIAE
ELDIGLEQIQIEAAPPDDAYVTRELGTQATGGSTSTIATWKSLREAGAVARTLLVQAAAAQWSVDPASCTTGGGMVRHEA
TGRSLAYGELATAAAALPVPAAPVTLRDPSSFRLVGRSQHRLDAPAKVAGTATFGIDVQVPGMRIGTVAACPVMGGVLAH
VDDSAARQVPGVRDVLTIGNAVCVVGNHFWAARKGLDALVITWDEGVNAAVSTDTIYRQLHEALDGPAITAHAKGDARAA
IAGATTRVEAVYQQPLLAHAPMEPINCTVQVTPERCDIWVGSQVPMRARDAAADITGLGKDRVHVHNQYIGGGFGRRLEH
EYVIQAVQFARQVAYPLKIVWTREEDLTLDRFRPAYVDRLVGGLDRKGNLVGLSHRIVGPAVVARWAPEALLPNGVDDDL
LAATVETPYAIPAMFLDYARREAPGVVTAWWRGVGGTRGVFVVESFIDELAARAGKDAVAFRRQMTGGNPRARAVLDLAA
EKASWGEPLPKHVGRGIALQYVFGSYLATVMEVDMSDMDTVRVLRAVVAVDCGRMVNPDQVVSQIEGGLIFGISAALFNE
VTLRDGRVQETNFHSYRVLRMNESPMIEVHLVNSTEDPGGIGETGTAAAAAALANAMAAATGRRYRRLPLTGPQA
>Mature_714_residues
GRTMLSRRQALAGTGGLLLAAMLPRGAARAATRIVEDQTGPFAPNAFVRIAPDGAITLILPNVEMGQGIYTGEAMLIAEE
LDIGLEQIQIEAAPPDDAYVTRELGTQATGGSTSTIATWKSLREAGAVARTLLVQAAAAQWSVDPASCTTGGGMVRHEAT
GRSLAYGELATAAAALPVPAAPVTLRDPSSFRLVGRSQHRLDAPAKVAGTATFGIDVQVPGMRIGTVAACPVMGGVLAHV
DDSAARQVPGVRDVLTIGNAVCVVGNHFWAARKGLDALVITWDEGVNAAVSTDTIYRQLHEALDGPAITAHAKGDARAAI
AGATTRVEAVYQQPLLAHAPMEPINCTVQVTPERCDIWVGSQVPMRARDAAADITGLGKDRVHVHNQYIGGGFGRRLEHE
YVIQAVQFARQVAYPLKIVWTREEDLTLDRFRPAYVDRLVGGLDRKGNLVGLSHRIVGPAVVARWAPEALLPNGVDDDLL
AATVETPYAIPAMFLDYARREAPGVVTAWWRGVGGTRGVFVVESFIDELAARAGKDAVAFRRQMTGGNPRARAVLDLAAE
KASWGEPLPKHVGRGIALQYVFGSYLATVMEVDMSDMDTVRVLRAVVAVDCGRMVNPDQVVSQIEGGLIFGISAALFNEV
TLRDGRVQETNFHSYRVLRMNESPMIEVHLVNSTEDPGGIGETGTAAAAAALANAMAAATGRRYRRLPLTGPQA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=383, Percent_Identity=26.6318537859008, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 75857; Mature: 75725

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRTMLSRRQALAGTGGLLLAAMLPRGAARAATRIVEDQTGPFAPNAFVRIAPDGAITLI
CCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEE
LPNVEMGQGIYTGEAMLIAEELDIGLEQIQIEAAPPDDAYVTRELGTQATGGSTSTIATW
ECCCCCCCCEEECCEEEEEEHHCCCEEEEEEECCCCCCCEEEHHHCCCCCCCCCHHHHHH
KSLREAGAVARTLLVQAAAAQWSVDPASCTTGGGMVRHEATGRSLAYGELATAAAALPVP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCEEHHHHHHHHHHCCCC
AAPVTLRDPSSFRLVGRSQHRLDAPAKVAGTATFGIDVQVPGMRIGTVAACPVMGGVLAH
CCCEEECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEEEECCEEECHHHHHHHHCCHHHH
VDDSAARQVPGVRDVLTIGNAVCVVGNHFWAARKGLDALVITWDEGVNAAVSTDTIYRQL
CCCHHHHHCCCHHHHHHHCCEEEEECCCHHHHHCCCCEEEEEECCCCCCEEHHHHHHHHH
HEALDGPAITAHAKGDARAAIAGATTRVEAVYQQPLLAHAPMEPINCTVQVTPERCDIWV
HHHHCCCEEEEECCCCCCEEEECCHHHHHHHHHCCHHHCCCCCCCEEEEEECCCCCCEEE
GSQVPMRARDAAADITGLGKDRVHVHNQYIGGGFGRRLEHEYVIQAVQFARQVAYPLKIV
CCCCCCCHHHHHHHHHCCCCCCEEEECEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
WTREEDLTLDRFRPAYVDRLVGGLDRKGNLVGLSHRIVGPAVVARWAPEALLPNGVDDDL
EECCCCCCHHHCCHHHHHHHHCCCCCCCCEEEECHHHHCHHHHHHCCCHHHCCCCCCHHH
LAATVETPYAIPAMFLDYARREAPGVVTAWWRGVGGTRGVFVVESFIDELAARAGKDAVA
HEEECCCCCHHHHHHHHHHHHCCCCEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
FRRQMTGGNPRARAVLDLAAEKASWGEPLPKHVGRGIALQYVFGSYLATVMEVDMSDMDT
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEHHHHHHHHHHHHHHCCCCHHH
VRVLRAVVAVDCGRMVNPDQVVSQIEGGLIFGISAALFNEVTLRDGRVQETNFHSYRVLR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHEECCCEEECCCCCEEEEEE
MNESPMIEVHLVNSTEDPGGIGETGTAAAAAALANAMAAATGRRYRRLPLTGPQA
ECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
>Mature Secondary Structure 
GRTMLSRRQALAGTGGLLLAAMLPRGAARAATRIVEDQTGPFAPNAFVRIAPDGAITLI
CCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEE
LPNVEMGQGIYTGEAMLIAEELDIGLEQIQIEAAPPDDAYVTRELGTQATGGSTSTIATW
ECCCCCCCCEEECCEEEEEEHHCCCEEEEEEECCCCCCCEEEHHHCCCCCCCCCHHHHHH
KSLREAGAVARTLLVQAAAAQWSVDPASCTTGGGMVRHEATGRSLAYGELATAAAALPVP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCEEHHHHHHHHHHCCCC
AAPVTLRDPSSFRLVGRSQHRLDAPAKVAGTATFGIDVQVPGMRIGTVAACPVMGGVLAH
CCCEEECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEEEECCEEECHHHHHHHHCCHHHH
VDDSAARQVPGVRDVLTIGNAVCVVGNHFWAARKGLDALVITWDEGVNAAVSTDTIYRQL
CCCHHHHHCCCHHHHHHHCCEEEEECCCHHHHHCCCCEEEEEECCCCCCEEHHHHHHHHH
HEALDGPAITAHAKGDARAAIAGATTRVEAVYQQPLLAHAPMEPINCTVQVTPERCDIWV
HHHHCCCEEEEECCCCCCEEEECCHHHHHHHHHCCHHHCCCCCCCEEEEEECCCCCCEEE
GSQVPMRARDAAADITGLGKDRVHVHNQYIGGGFGRRLEHEYVIQAVQFARQVAYPLKIV
CCCCCCCHHHHHHHHHCCCCCCEEEECEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
WTREEDLTLDRFRPAYVDRLVGGLDRKGNLVGLSHRIVGPAVVARWAPEALLPNGVDDDL
EECCCCCCHHHCCHHHHHHHHCCCCCCCCEEEECHHHHCHHHHHHCCCHHHCCCCCCHHH
LAATVETPYAIPAMFLDYARREAPGVVTAWWRGVGGTRGVFVVESFIDELAARAGKDAVA
HEEECCCCCHHHHHHHHHHHHCCCCEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
FRRQMTGGNPRARAVLDLAAEKASWGEPLPKHVGRGIALQYVFGSYLATVMEVDMSDMDT
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEHHHHHHHHHHHHHHCCCCHHH
VRVLRAVVAVDCGRMVNPDQVVSQIEGGLIFGISAALFNEVTLRDGRVQETNFHSYRVLR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEHHHHHHHHEECCCEEECCCCCEEEEEE
MNESPMIEVHLVNSTEDPGGIGETGTAAAAAALANAMAAATGRRYRRLPLTGPQA
ECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]