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The map label for this gene is tolC [H]

Identifier: 162147546

GI number: 162147546

Start: 1785902

End: 1787335

Strand: Direct

Name: tolC [H]

Synonym: GDI_1762

Alternate gene names: 162147546

Gene position: 1785902-1787335 (Clockwise)

Preceding gene: 162147545

Following gene: 162147547

Centisome position: 45.28

GC content: 68.76

Gene sequence:

>1434_bases
ATGAAGCGGAACTGTGGGATCGGGGCGGGGCTGGCGGCGCTGCTGTGCGGCACCACGGCCTGGGCCCAGCGCTATGACGG
CAGCGGGTCCCCGTCCTTCGTTCCCCATACGCTGCAGGAAGCGCTGGCGGCGTCCTACCTGACCAATCCGACGCTGCAGC
AGGAGCGCGCGGCCCTGCGCGCGACGGACGAGCAGGTGCCGACCGCGCTCGCCGGCTGGCGCCCGACCGTCAGCACCAAC
GTGAACATGACCTATTACTCCGGCCTCAACGCGGTGGCGCGGCAGGAAGGGTACGCCTGGTATTCAAGGCGGTTCGACGT
GCCGGGCTATACCGGCGGCGTGTCGCTTTCCCAGCCGATCTATACCGGCGGCAAGACCACCGCCAGCACCCACAAGGCGG
TCAATGCCGTGATGGCGGAACGCGCCCGGCTGATCGCGACCGAACAGCAGGTCTTCAGCAGCGTCGTCAGCGCCTATGTC
GGCGTGATCGAAGACGAACAGTTGCTGCAGTTGAACATCAATAACGAGAAGGTGCTGCAGGAACAGCTCCGCGCCACGTC
CGAGCGCTTCCGCGTGGGCGAGATCACCCGCACCGACGTGGCCCAGGCCGAGGCCGCGCTGGCCAGCGCCCGCGCCGCCC
GGCAGGAGGCCGAGGGCACGCTGCAGACGGCGCAGGCGACCTACACCCAGGTGGTCGGCATGTCGCCGCCCCCCAACCTG
GTGCCGCCGCAGCCGCTGGTGCTGCCGGTGAAGTCGCAGAACGAGGCGATCGCCCAGGCGGTGCAGAACAATCCGAACGT
GATCGCCGCCCTGTTCTCCGAGGCGTCGAACAAGGACGGGGTCGCCGTCGCCATGGCGGCGATCCTGCCCAAGGTGACGG
CCGATGCCAGCTACGTCCACAGCATCAACCAGAGCAGCGGCCGGTCGCTGGAGGACGAGAAATACGCGACGCTGAACGTC
CAGTTCCCGCTCTACCAGGGCGGATCGGAATATGCCGCCGTCCGCCAGGCGCGCCAGCAGGTGGCCCAGGCGCATCGCGC
GGTCGACATCCAGCGCCGCGCCGCGTTGCAGCTCGCCTCGTCCAACTGGCAGCAACTGATGGCCTATGCGGCCTCGATCC
AGAGCGACCGCACCGCCATCGCGTCGAACATCGTCGCCCTGGACGGGGTGGAGCGCCAGGCGATCGTGGGCACCAGCACG
ACGCTGGAAGTCCTGCAGCAGCAGCAGACCCTGCTTCAGGCCCAGGTCGCGCTGGTGCAGAGCCTGAGCAATCTCGTCAC
CGCGTCATACGGCGTGGCGGCCGCTATCGGGCGGCTGACGGCGGCGGACCTGAAGCTGGACGTCCCGCGCTATGACGAGA
CCGCCTATTACAAGGCGGTCAAGGACCGCCCGTGGGGCATCGGCGACCAGGCCACCGACCAGCCAGGCCGCTGA

Upstream 100 bases:

>100_bases
GCCTGCCTTTGCGTTCTGAAGGCTGTAAACCCGTTCGCAACCGTTTGCGTGCATGAAACACGTCATGCGGCCTGAGGTGG
CATTGTCGCGGGGGAGCGGA

Downstream 100 bases:

>100_bases
CAGGCTGCTTCAAAAGCCCCGCTGCCGGCGATCCGACGCGCGTTTTCTGTGCTTCGATGCTCTCGGCCCGTAAGGTCGCT
CCGCTTCGATGCTCGAAAAC

Product: outer membrane protein tolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MKRNCGIGAGLAALLCGTTAWAQRYDGSGSPSFVPHTLQEALAASYLTNPTLQQERAALRATDEQVPTALAGWRPTVSTN
VNMTYYSGLNAVARQEGYAWYSRRFDVPGYTGGVSLSQPIYTGGKTTASTHKAVNAVMAERARLIATEQQVFSSVVSAYV
GVIEDEQLLQLNINNEKVLQEQLRATSERFRVGEITRTDVAQAEAALASARAARQEAEGTLQTAQATYTQVVGMSPPPNL
VPPQPLVLPVKSQNEAIAQAVQNNPNVIAALFSEASNKDGVAVAMAAILPKVTADASYVHSINQSSGRSLEDEKYATLNV
QFPLYQGGSEYAAVRQARQQVAQAHRAVDIQRRAALQLASSNWQQLMAYAASIQSDRTAIASNIVALDGVERQAIVGTST
TLEVLQQQQTLLQAQVALVQSLSNLVTASYGVAAAIGRLTAADLKLDVPRYDETAYYKAVKDRPWGIGDQATDQPGR

Sequences:

>Translated_477_residues
MKRNCGIGAGLAALLCGTTAWAQRYDGSGSPSFVPHTLQEALAASYLTNPTLQQERAALRATDEQVPTALAGWRPTVSTN
VNMTYYSGLNAVARQEGYAWYSRRFDVPGYTGGVSLSQPIYTGGKTTASTHKAVNAVMAERARLIATEQQVFSSVVSAYV
GVIEDEQLLQLNINNEKVLQEQLRATSERFRVGEITRTDVAQAEAALASARAARQEAEGTLQTAQATYTQVVGMSPPPNL
VPPQPLVLPVKSQNEAIAQAVQNNPNVIAALFSEASNKDGVAVAMAAILPKVTADASYVHSINQSSGRSLEDEKYATLNV
QFPLYQGGSEYAAVRQARQQVAQAHRAVDIQRRAALQLASSNWQQLMAYAASIQSDRTAIASNIVALDGVERQAIVGTST
TLEVLQQQQTLLQAQVALVQSLSNLVTASYGVAAAIGRLTAADLKLDVPRYDETAYYKAVKDRPWGIGDQATDQPGR
>Mature_477_residues
MKRNCGIGAGLAALLCGTTAWAQRYDGSGSPSFVPHTLQEALAASYLTNPTLQQERAALRATDEQVPTALAGWRPTVSTN
VNMTYYSGLNAVARQEGYAWYSRRFDVPGYTGGVSLSQPIYTGGKTTASTHKAVNAVMAERARLIATEQQVFSSVVSAYV
GVIEDEQLLQLNINNEKVLQEQLRATSERFRVGEITRTDVAQAEAALASARAARQEAEGTLQTAQATYTQVVGMSPPPNL
VPPQPLVLPVKSQNEAIAQAVQNNPNVIAALFSEASNKDGVAVAMAAILPKVTADASYVHSINQSSGRSLEDEKYATLNV
QFPLYQGGSEYAAVRQARQQVAQAHRAVDIQRRAALQLASSNWQQLMAYAASIQSDRTAIASNIVALDGVERQAIVGTST
TLEVLQQQQTLLQAQVALVQSLSNLVTASYGVAAAIGRLTAADLKLDVPRYDETAYYKAVKDRPWGIGDQATDQPGR

Specific function: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=425, Percent_Identity=23.7647058823529, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51157; Mature: 51157

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNCGIGAGLAALLCGTTAWAQRYDGSGSPSFVPHTLQEALAASYLTNPTLQQERAALR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
ATDEQVPTALAGWRPTVSTNVNMTYYSGLNAVARQEGYAWYSRRFDVPGYTGGVSLSQPI
HCHHHCCHHHHCCCCCCCCCCEEEEECCCHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCE
YTGGKTTASTHKAVNAVMAERARLIATEQQVFSSVVSAYVGVIEDEQLLQLNINNEKVLQ
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
EQLRATSERFRVGEITRTDVAQAEAALASARAARQEAEGTLQTAQATYTQVVGMSPPPNL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VPPQPLVLPVKSQNEAIAQAVQNNPNVIAALFSEASNKDGVAVAMAAILPKVTADASYVH
CCCCCEEEECCCCCHHHHHHHHCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
SINQSSGRSLEDEKYATLNVQFPLYQGGSEYAAVRQARQQVAQAHRAVDIQRRAALQLAS
HCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNWQQLMAYAASIQSDRTAIASNIVALDGVERQAIVGTSTTLEVLQQQQTLLQAQVALVQ
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SLSNLVTASYGVAAAIGRLTAADLKLDVPRYDETAYYKAVKDRPWGIGDQATDQPGR
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRNCGIGAGLAALLCGTTAWAQRYDGSGSPSFVPHTLQEALAASYLTNPTLQQERAALR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
ATDEQVPTALAGWRPTVSTNVNMTYYSGLNAVARQEGYAWYSRRFDVPGYTGGVSLSQPI
HCHHHCCHHHHCCCCCCCCCCEEEEECCCHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCE
YTGGKTTASTHKAVNAVMAERARLIATEQQVFSSVVSAYVGVIEDEQLLQLNINNEKVLQ
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
EQLRATSERFRVGEITRTDVAQAEAALASARAARQEAEGTLQTAQATYTQVVGMSPPPNL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VPPQPLVLPVKSQNEAIAQAVQNNPNVIAALFSEASNKDGVAVAMAAILPKVTADASYVH
CCCCCEEEECCCCCHHHHHHHHCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
SINQSSGRSLEDEKYATLNVQFPLYQGGSEYAAVRQARQQVAQAHRAVDIQRRAALQLAS
HCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNWQQLMAYAASIQSDRTAIASNIVALDGVERQAIVGTSTTLEVLQQQQTLLQAQVALVQ
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SLSNLVTASYGVAAAIGRLTAADLKLDVPRYDETAYYKAVKDRPWGIGDQATDQPGR
HHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]