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The map label for this gene is glpD [H]

Identifier: 162147535

GI number: 162147535

Start: 1774579

End: 1776273

Strand: Direct

Name: glpD [H]

Synonym: GDI_1751

Alternate gene names: 162147535

Gene position: 1774579-1776273 (Clockwise)

Preceding gene: 162147534

Following gene: 162147536

Centisome position: 44.99

GC content: 68.73

Gene sequence:

>1695_bases
TTGTCACAAAAACGTGCCTTGTCCCGCTATGAGAGAGGCTTGAAGACCCCTACGATGTTCGTTTACGAACATCGTAGGGA
GGAAACGAGCATGCTGTCCGAAGCATCGAACGGGGGCGAACCGGCGCGGCCCCCTTATGACCTGCTGATCGTGGGGGGTG
GCATCAACGGTGCCGGGATCGCGCGGGATGCCGTGGGACGGGGCGCGTCGGTGCTGCTGGTGGAACAGCACGACCTGGCC
AGCCATACCTCGTCGGCCAGCACCAAGCTGATCCATGGCGGCCTGCGCTATCTGGAATATTACGAATTCCGCCTGGTGCG
CGAAGCGCTGATCGAGCGCGAGCGGCTGCTGCGCATCGCGCCGCACATCATCTGGCCGCTGTCGTTCGTGCTGCCGCATT
CGCGGCTGGTGCGGCCGGCGTGGATGCTGCGGCTGGGCCTGTTCCTCTACGACCATCTGGGGGGCAGGATGACCCTGCCG
CGCTCGCGCGGCGTGCGGCTGGACCGCGATCCGCTGGGGGTGCCGTTGCAGCCGGCCTTCAAGCGGGGATTCGTCTATTC
CGACGGCTGGGTGCAGGACAGCCGGCTGGTGGTGCTGAACGCGATGGATGCCCGGACGCGCGGCGCGGACATCCGCACCC
GCACCACGCTGGTCGATGCCCGGCGCGTGGACGGTTTGTGGCAGGCCACGCTGGCCGATGCGGCGGGCGGGACCCGCACG
GTCCGGGCACGGGCCCTGGTCAACGCTGCCGGGCCCTGGGTGGGCAGCATGCTGCGCGACCGGCTGGGCATCGCCACCAC
GAAGCAGGTGCGGCTGGTCAAGGGCAGCCATATCGTGGTGCCGCGCCAGTTCGAAGGCGAACAGGCCTATATCTTCCAGA
ATCCCGACAAGCGGATCGTCTTCGCCATTCCCTACGAACGGCAGTTCACCCTGATCGGCACCACCGACCTGCCGTGGACC
ACCGATCCGGGACAGGTCGAGATCTCCGCCGATGAAATTCGCTATCTGTGCGACAGTGTGAACCGCTATCTGCGCAGCCC
GGTCTCGCCCGCCGATGTCGTGTGGTCCTATGCCGGCGTGCGGCCGCTCTATGACGACGCGGCGCGGAACGCATCGGCGG
TAACGCGCGATTATGTGCTGGACGTCGATGTGGCCGCCGGGGCGCACCCTGCCGACGCGGCGCCGCTGCTGTCGATCTTC
GGCGGCAAGATCACGACCTATCGCCGGCTGGCCGAACATGCGCTGGAAAAGCTGGCGCCGTTCCTGCCGGTCCTGAAGGG
CAACGGATGGACCGCCGAGCGCGCCCTGCCGGGCGGTGACCTGGGCCCGGGCGGGTTCGATTCCGCCCTGGCGCGGCTGC
GCAAGGACGCGCCCTTCCTGTCGGCCGAGGAGTCCTGGCGGCTGGTCCGCGATTACGGATCGCGGGCCTGGACCATCATC
GGCGATGCGCGCGGCCCGGCGGACCTGGGCGAATCGTTCGGCGGCGGCCTGACGGCGCGCGAGGTCGATTACCTTGTCCG
CCAGGAATGGGCGGTGACGGCCGAGGACATCCTCTGGCGTCGCTCCCGCCTCGGGCTGCATGTCACGGACGAGGATGTCG
CGCGCCTGGACCGCTACCTGCGCGACCGGCAGCGGGACGCCGCCCCCGAAGACAGACGCGAACCATGCCCGGCCCGGGTC
GCCCTGGCCGGCTGA

Upstream 100 bases:

>100_bases
GACGCGCATCGGGTCGCCCTGCATATCGCCGAGTCCTGAGCGAAAACCCTCGTTCCAAAACGAACATTTCTGCTGCTGCC
TGCCGCTGAAACTGCGCAAA

Downstream 100 bases:

>100_bases
CCGCGCCGGCCGAATACCGAAAACCACACATTTCCCCAACAAGAAACCGAAAAGAAGTGGGACATGTTCAGGAACAGACA
ATTCATCGGGGAGCTGATCT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MSQKRALSRYERGLKTPTMFVYEHRREETSMLSEASNGGEPARPPYDLLIVGGGINGAGIARDAVGRGASVLLVEQHDLA
SHTSSASTKLIHGGLRYLEYYEFRLVREALIERERLLRIAPHIIWPLSFVLPHSRLVRPAWMLRLGLFLYDHLGGRMTLP
RSRGVRLDRDPLGVPLQPAFKRGFVYSDGWVQDSRLVVLNAMDARTRGADIRTRTTLVDARRVDGLWQATLADAAGGTRT
VRARALVNAAGPWVGSMLRDRLGIATTKQVRLVKGSHIVVPRQFEGEQAYIFQNPDKRIVFAIPYERQFTLIGTTDLPWT
TDPGQVEISADEIRYLCDSVNRYLRSPVSPADVVWSYAGVRPLYDDAARNASAVTRDYVLDVDVAAGAHPADAAPLLSIF
GGKITTYRRLAEHALEKLAPFLPVLKGNGWTAERALPGGDLGPGGFDSALARLRKDAPFLSAEESWRLVRDYGSRAWTII
GDARGPADLGESFGGGLTAREVDYLVRQEWAVTAEDILWRRSRLGLHVTDEDVARLDRYLRDRQRDAAPEDRREPCPARV
ALAG

Sequences:

>Translated_564_residues
MSQKRALSRYERGLKTPTMFVYEHRREETSMLSEASNGGEPARPPYDLLIVGGGINGAGIARDAVGRGASVLLVEQHDLA
SHTSSASTKLIHGGLRYLEYYEFRLVREALIERERLLRIAPHIIWPLSFVLPHSRLVRPAWMLRLGLFLYDHLGGRMTLP
RSRGVRLDRDPLGVPLQPAFKRGFVYSDGWVQDSRLVVLNAMDARTRGADIRTRTTLVDARRVDGLWQATLADAAGGTRT
VRARALVNAAGPWVGSMLRDRLGIATTKQVRLVKGSHIVVPRQFEGEQAYIFQNPDKRIVFAIPYERQFTLIGTTDLPWT
TDPGQVEISADEIRYLCDSVNRYLRSPVSPADVVWSYAGVRPLYDDAARNASAVTRDYVLDVDVAAGAHPADAAPLLSIF
GGKITTYRRLAEHALEKLAPFLPVLKGNGWTAERALPGGDLGPGGFDSALARLRKDAPFLSAEESWRLVRDYGSRAWTII
GDARGPADLGESFGGGLTAREVDYLVRQEWAVTAEDILWRRSRLGLHVTDEDVARLDRYLRDRQRDAAPEDRREPCPARV
ALAG
>Mature_563_residues
SQKRALSRYERGLKTPTMFVYEHRREETSMLSEASNGGEPARPPYDLLIVGGGINGAGIARDAVGRGASVLLVEQHDLAS
HTSSASTKLIHGGLRYLEYYEFRLVREALIERERLLRIAPHIIWPLSFVLPHSRLVRPAWMLRLGLFLYDHLGGRMTLPR
SRGVRLDRDPLGVPLQPAFKRGFVYSDGWVQDSRLVVLNAMDARTRGADIRTRTTLVDARRVDGLWQATLADAAGGTRTV
RARALVNAAGPWVGSMLRDRLGIATTKQVRLVKGSHIVVPRQFEGEQAYIFQNPDKRIVFAIPYERQFTLIGTTDLPWTT
DPGQVEISADEIRYLCDSVNRYLRSPVSPADVVWSYAGVRPLYDDAARNASAVTRDYVLDVDVAAGAHPADAAPLLSIFG
GKITTYRRLAEHALEKLAPFLPVLKGNGWTAERALPGGDLGPGGFDSALARLRKDAPFLSAEESWRLVRDYGSRAWTIIG
DARGPADLGESFGGGLTAREVDYLVRQEWAVTAEDILWRRSRLGLHVTDEDVARLDRYLRDRQRDAAPEDRREPCPARVA
LAG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=519, Percent_Identity=31.9845857418112, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI285002231, Length=519, Percent_Identity=31.9845857418112, Blast_Score=182, Evalue=1e-45,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=49.364406779661, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1788574, Length=409, Percent_Identity=28.6063569682152, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17509253, Length=527, Percent_Identity=29.7912713472486, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI115534726, Length=545, Percent_Identity=28.256880733945, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=567, Percent_Identity=27.8659611992945, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI161077125, Length=538, Percent_Identity=31.9702602230483, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24653942, Length=538, Percent_Identity=31.9702602230483, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24653944, Length=538, Percent_Identity=31.9702602230483, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI20130025, Length=538, Percent_Identity=31.9702602230483, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24586295, Length=520, Percent_Identity=27.8846153846154, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI19921278, Length=530, Percent_Identity=23.9622641509434, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62701; Mature: 62570

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKRALSRYERGLKTPTMFVYEHRREETSMLSEASNGGEPARPPYDLLIVGGGINGAGI
CCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCC
ARDAVGRGASVLLVEQHDLASHTSSASTKLIHGGLRYLEYYEFRLVREALIERERLLRIA
CHHHHCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PHIIWPLSFVLPHSRLVRPAWMLRLGLFLYDHLGGRMTLPRSRGVRLDRDPLGVPLQPAF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCCCCCCCCHHH
KRGFVYSDGWVQDSRLVVLNAMDARTRGADIRTRTTLVDARRVDGLWQATLADAAGGTRT
HCCCEECCCCCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHCHHHHHHHHHCCCCCCE
VRARALVNAAGPWVGSMLRDRLGIATTKQVRLVKGSHIVVPRQFEGEQAYIFQNPDKRIV
EHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCEEEEEECCCCEEE
FAIPYERQFTLIGTTDLPWTTDPGQVEISADEIRYLCDSVNRYLRSPVSPADVVWSYAGV
EEECCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
RPLYDDAARNASAVTRDYVLDVDVAAGAHPADAAPLLSIFGGKITTYRRLAEHALEKLAP
CCHHHHHHCCHHHHHHHEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLPVLKGNGWTAERALPGGDLGPGGFDSALARLRKDAPFLSAEESWRLVRDYGSRAWTII
HHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEE
GDARGPADLGESFGGGLTAREVDYLVRQEWAVTAEDILWRRSRLGLHVTDEDVARLDRYL
ECCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEECHHHHHHHHHHH
RDRQRDAAPEDRREPCPARVALAG
HHHHHCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
SQKRALSRYERGLKTPTMFVYEHRREETSMLSEASNGGEPARPPYDLLIVGGGINGAGI
CHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCC
ARDAVGRGASVLLVEQHDLASHTSSASTKLIHGGLRYLEYYEFRLVREALIERERLLRIA
CHHHHCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PHIIWPLSFVLPHSRLVRPAWMLRLGLFLYDHLGGRMTLPRSRGVRLDRDPLGVPLQPAF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEECCCCCCCCCCHHH
KRGFVYSDGWVQDSRLVVLNAMDARTRGADIRTRTTLVDARRVDGLWQATLADAAGGTRT
HCCCEECCCCCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHCHHHHHHHHHCCCCCCE
VRARALVNAAGPWVGSMLRDRLGIATTKQVRLVKGSHIVVPRQFEGEQAYIFQNPDKRIV
EHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCEEEEEECCCCEEE
FAIPYERQFTLIGTTDLPWTTDPGQVEISADEIRYLCDSVNRYLRSPVSPADVVWSYAGV
EEECCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
RPLYDDAARNASAVTRDYVLDVDVAAGAHPADAAPLLSIFGGKITTYRRLAEHALEKLAP
CCHHHHHHCCHHHHHHHEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLPVLKGNGWTAERALPGGDLGPGGFDSALARLRKDAPFLSAEESWRLVRDYGSRAWTII
HHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEE
GDARGPADLGESFGGGLTAREVDYLVRQEWAVTAEDILWRRSRLGLHVTDEDVARLDRYL
ECCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEECHHHHHHHHHHH
RDRQRDAAPEDRREPCPARVALAG
HHHHHCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]