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The map label for this gene is glpR [H]

Identifier: 162147534

GI number: 162147534

Start: 1773744

End: 1774517

Strand: Direct

Name: glpR [H]

Synonym: GDI_1750

Alternate gene names: 162147534

Gene position: 1773744-1774517 (Clockwise)

Preceding gene: 162147533

Following gene: 162147535

Centisome position: 44.97

GC content: 68.22

Gene sequence:

>774_bases
ATGGCCGGCGTCCCGACCGAGGAACGGCACCGCGAAATCCTGTCCCTGGTGCGGACGCGGGGCTATGTCTCGAACGAGGA
CCTGGCCCAGCGGCTGCGCGTGGCCGTCCAGACCATCCGGCGCGATGTCAACCACCTGGCCGGATGCGGGCTGCTGACGC
GCCATCACGGCGGCGCGGGCCTGGTCTCGTCGATCGAAAACATCGCCTATGCGGAACGGCAGATCCTCAACCGCCGGGAA
AAGGAAGCGATCGGCCAGGTGGCGGCGCGGGAAATTCCCGACAATTCCTCGCTGTTCATCAATATCGGCACGACGACCGA
GGCGTTCGCGCGGGCGCTGCGCCACCACCGGGCGCTGCGGATCATCACCAACAACCTGCATGTGGCGTCCACCCTGGCGC
CGCAATCCGATTTCCGCGTCGTGATCGCCGGCGGGACGGTGCGCTCGCATGACGGCGGCATCACGGGGCCCACCGCGACC
GCGCTGATCGACCAGTATCGCGCCGATTTCGGCGTGATCGGCATCAGCGGGATCGAAGAGGATGGCACGCTGCTGGATTT
CGACCTGGACGAGATCGACCTGGCGCAGGCCATCATGCGCAACGCCCGCACGATTTTCCTGCTGGCCGACCATACCAAGT
TCGGGCGCCGGCCGATGGGGCGGGTGGGCCACCTGTCGGACGTGCAGGCGCTGTTCACCGACCGCGCGCCGCCCCCGGCG
GTGCGCGCGATCCTGGACGCGCATCGGGTCGCCCTGCATATCGCCGAGTCCTGA

Upstream 100 bases:

>100_bases
ACGCTGGACGCGCTGGCGCGGATCAAGGGCGTGGGGGCATCCAAGCTGGATCGCTATGGCGCGGCGGTGCTCCAGGTCCT
GGCCGGGGCGGACTAGGGCG

Downstream 100 bases:

>100_bases
GCGAAAACCCTCGTTCCAAAACGAACATTTCTGCTGCTGCCTGCCGCTGAAACTGCGCAAATTGTCACAAAAACGTGCCT
TGTCCCGCTATGAGAGAGGC

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAGVPTEERHREILSLVRTRGYVSNEDLAQRLRVAVQTIRRDVNHLAGCGLLTRHHGGAGLVSSIENIAYAERQILNRRE
KEAIGQVAAREIPDNSSLFINIGTTTEAFARALRHHRALRIITNNLHVASTLAPQSDFRVVIAGGTVRSHDGGITGPTAT
ALIDQYRADFGVIGISGIEEDGTLLDFDLDEIDLAQAIMRNARTIFLLADHTKFGRRPMGRVGHLSDVQALFTDRAPPPA
VRAILDAHRVALHIAES

Sequences:

>Translated_257_residues
MAGVPTEERHREILSLVRTRGYVSNEDLAQRLRVAVQTIRRDVNHLAGCGLLTRHHGGAGLVSSIENIAYAERQILNRRE
KEAIGQVAAREIPDNSSLFINIGTTTEAFARALRHHRALRIITNNLHVASTLAPQSDFRVVIAGGTVRSHDGGITGPTAT
ALIDQYRADFGVIGISGIEEDGTLLDFDLDEIDLAQAIMRNARTIFLLADHTKFGRRPMGRVGHLSDVQALFTDRAPPPA
VRAILDAHRVALHIAES
>Mature_256_residues
AGVPTEERHREILSLVRTRGYVSNEDLAQRLRVAVQTIRRDVNHLAGCGLLTRHHGGAGLVSSIENIAYAERQILNRREK
EAIGQVAAREIPDNSSLFINIGTTTEAFARALRHHRALRIITNNLHVASTLAPQSDFRVVIAGGTVRSHDGGITGPTATA
LIDQYRADFGVIGISGIEEDGTLLDFDLDEIDLAQAIMRNARTIFLLADHTKFGRRPMGRVGHLSDVQALFTDRAPPPAV
RAILDAHRVALHIAES

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=248, Percent_Identity=48.3870967741936, Blast_Score=245, Evalue=2e-66,
Organism=Escherichia coli, GI87082344, Length=244, Percent_Identity=44.672131147541, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1789059, Length=240, Percent_Identity=27.5, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=26.2948207171315, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI226510968, Length=254, Percent_Identity=27.9527559055118, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789519, Length=236, Percent_Identity=25, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=24.4541484716157, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=25.8964143426295, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790753, Length=240, Percent_Identity=22.0833333333333, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=24.3027888446215, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787063, Length=249, Percent_Identity=22.8915662650602, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28104; Mature: 27973

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVPTEERHREILSLVRTRGYVSNEDLAQRLRVAVQTIRRDVNHLAGCGLLTRHHGGAG
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCHH
LVSSIENIAYAERQILNRREKEAIGQVAAREIPDNSSLFINIGTTTEAFARALRHHRALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHEEE
IITNNLHVASTLAPQSDFRVVIAGGTVRSHDGGITGPTATALIDQYRADFGVIGISGIEE
EEECCEEEEEECCCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
DGTLLDFDLDEIDLAQAIMRNARTIFLLADHTKFGRRPMGRVGHLSDVQALFTDRAPPPA
CCCEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
VRAILDAHRVALHIAES
HHHHHHHHHHHEEEECC
>Mature Secondary Structure 
AGVPTEERHREILSLVRTRGYVSNEDLAQRLRVAVQTIRRDVNHLAGCGLLTRHHGGAG
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCHH
LVSSIENIAYAERQILNRREKEAIGQVAAREIPDNSSLFINIGTTTEAFARALRHHRALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHEEE
IITNNLHVASTLAPQSDFRVVIAGGTVRSHDGGITGPTATALIDQYRADFGVIGISGIEE
EEECCEEEEEECCCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
DGTLLDFDLDEIDLAQAIMRNARTIFLLADHTKFGRRPMGRVGHLSDVQALFTDRAPPPA
CCCEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
VRAILDAHRVALHIAES
HHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]