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The map label for this gene is flhA [H]

Identifier: 162147429

GI number: 162147429

Start: 1666930

End: 1669179

Strand: Reverse

Name: flhA [H]

Synonym: GDI_1645

Alternate gene names: 162147429

Gene position: 1669179-1666930 (Counterclockwise)

Preceding gene: 162147432

Following gene: 162147423

Centisome position: 42.32

GC content: 64.4

Gene sequence:

>2250_bases
ATGTGCCTTGCGGAAGGGCAGTGGCTCATCCCCACACGAAAGGAAACACGGCTCTTGGATACCGCCGGTGGCAGCGAAAT
CAAGAAGCCGGGCGGCGGCAGACTGGCCGAAATAACGGCCGCAGCGCGACAGAAGATTTCATCTGCCTCCCGCAACGTGA
CCCTTTCGGCCGAGACGCTGCGAAGCGGGGGATGGCGGGCAACCTCATGGCGTTCCCTGGTTCCCGGCACGGACGTTGGC
CTCGCCCTGGGCGTGGTCGTCCTGCTGGCCATCCTGATCATTCCGCTTCCGACCTTCATCCTCGACATGGGTCTTTCGCT
GTCGATCACGTCGTCCGTGCTGGTCCTGATGGTGGCGCTGTTCCTCGAGCGCACGCTCGACTTCACGTCGTTTCCCACCC
TGCTCCTGCTGACGACCCTGCTGCGCCTGTCGCTCGAAATCGCGACCACGCGCCTGATCCTCAGCCATGGCAGCGAGGGC
ACCTACGCCGCCGGACATGTGGTGGCCGCCTTCGGCGGGTTCCTGATGGGGGGCGACCTTTTCATCGGCGGGATCGTGTT
CTGCATCCTGCTGGTCGTGAACTTCATGGTCATCACGAAGGGTTCGGGACGCATCGCCGAAGTGGCGGCCCGGTTCTTCC
TGGACTCGATGCCCGGCAAGCAGATGGCGATCGATGCCGACCTCTCGTCCGGGGCGATCAACGAACGGACCGCGCGCGCG
AAACGCAAGGAACTGGAAGACGAGAGCGCCTTCTACGGCGCGATGGACGGCGCCGCCAAGTTCGTTCGGGGAGACGCGAT
CGCCGGCCTGATCATCACGGCGATCAACATCGTCGGCGGCCTGGCCATCGGTATCCTGCGGCATGACATGCCCCTGAGCG
AGGCCGCCAGCACCTTTACCACGCTGACGGTCGGTGACGGGCTGGTCTCGCAAATCCCCGCCCTGCTGGTGTCGACCGCC
GCCGGTATCGTCGTCACCAAGGGGGGCTCCGACGGATCGACCGACGTCACGCTGGTCCGGCAGTTGGGCGGCAATCCTAA
ACCGCTGGCCGTCGCCGGCGGGCTGTCGGCCCTCTTCGCCATCATGCCCGGTCTGCCCGCCCTTCCCTTCCTCGTCATCG
CCGTCGGGGCCGGCATCGGGGCGTGGATGCGCCACAAGACCCCCGTCAAGGATGGGGACGGAGACGTCACCCAGATCTCG
CCCCAGCCGACGGCGCCGCCGATTTCCGAGATGCTCAAGCTGGACCTGCTGCGCCTGGAACTCGGCTTCGGCCTCCTGCC
CCTGACGAGCGGCGAGAATCCGCAACTGACCGAACAGATCAAGGCGCTGCGCCGGACGGTTGCCACCGAACTGGGATTCA
TCACCCCGCCCGTGCGGATACAGGACAACATCCTGCTTCCGTCGGATAATTACGTCATCAAGCTCAAGGAAATCGAAATC
GGATCCGGCGAGGTCAAGCCGGGGAAACTGATGGCCATGAGTCCGTCCGGCGGCGCGCCGGACCTTCCTGGCGACCGGAC
GACGGAGCCGGCATTCGGCCTTCCCGCCGTATGGATCGACCCCTCGCTCAAGCCCAAGGCGGTCGCCATGAAATGCACCA
TCGTGGACCCGGCCAGCGTCATCGTCACGCATCTCAGCGAGGCGGTGAGGCAGAACTTGCCCGACCTGCTGACCTATGTC
GCCACCCAGACATTGCTGGACGACCTTCCGCGTGAGCAGCAGAAGCTGGTCAACGACCTGATTCCGTCGCAGGTGCCGTT
AAGCACGATCCAGCGTGTCCTGCAGTCGCTCCTGGCCGAGCGCGTCTCGATCCGCGATCTTCCGACCATCCTCGAGAGCA
TCCAGGAAGGATGCAGCCTTGGCCTCCGTGGCGTGCAGGCCCTGACCGGCCACGTGCGGGTTCGCCTTTCCCGGCAGATC
TGCAACGCGCTGGTTGGCGGGGCCGGATACATTCCCATGATTACCCTGTCAGCGGAATGGGAGGCCGAATTCATGGCCCA
TATCACCGGACAGGCCGACGATCGGCGGCTGGCCATGCCGCCTTCCATGCTGAACAAATTCGTCGGAAAACTGCGCGAGG
TCTTCAATACGGTCTCGGCGAGCGGAGAGATCCCCGTCGTGGTCGTTTCCACCCCGGTCAGGGATTCCATGCGTTCGATC
GTGGAACGCGTGCGCCCATCGGTTTCGGTCCTCTCGCAATCCGAGATATATCCGCGCTCTCGCATCAAGACGGTCGCGAC
AATCACCTGA

Upstream 100 bases:

>100_bases
GTCATTTTCCGGCCTTGCCCGGGACCCGCGATAACGGTAGTTTCCGGCCCTGAAGTCACAGCCCGGTGACCGGGACGAAT
GGCCGGGCAGGCCGCTGGCC

Downstream 100 bases:

>100_bases
GGGCGTTACCGTCTCCCACACAGGACCAACAGCATACAAAAAAGCCCGGGCAGAACCCGGGCTTTTTTCGTCGAATGGTT
ATTGCCAGGAAGGCTTCAGC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MCLAEGQWLIPTRKETRLLDTAGGSEIKKPGGGRLAEITAAARQKISSASRNVTLSAETLRSGGWRATSWRSLVPGTDVG
LALGVVVLLAILIIPLPTFILDMGLSLSITSSVLVLMVALFLERTLDFTSFPTLLLLTTLLRLSLEIATTRLILSHGSEG
TYAAGHVVAAFGGFLMGGDLFIGGIVFCILLVVNFMVITKGSGRIAEVAARFFLDSMPGKQMAIDADLSSGAINERTARA
KRKELEDESAFYGAMDGAAKFVRGDAIAGLIITAINIVGGLAIGILRHDMPLSEAASTFTTLTVGDGLVSQIPALLVSTA
AGIVVTKGGSDGSTDVTLVRQLGGNPKPLAVAGGLSALFAIMPGLPALPFLVIAVGAGIGAWMRHKTPVKDGDGDVTQIS
PQPTAPPISEMLKLDLLRLELGFGLLPLTSGENPQLTEQIKALRRTVATELGFITPPVRIQDNILLPSDNYVIKLKEIEI
GSGEVKPGKLMAMSPSGGAPDLPGDRTTEPAFGLPAVWIDPSLKPKAVAMKCTIVDPASVIVTHLSEAVRQNLPDLLTYV
ATQTLLDDLPREQQKLVNDLIPSQVPLSTIQRVLQSLLAERVSIRDLPTILESIQEGCSLGLRGVQALTGHVRVRLSRQI
CNALVGGAGYIPMITLSAEWEAEFMAHITGQADDRRLAMPPSMLNKFVGKLREVFNTVSASGEIPVVVVSTPVRDSMRSI
VERVRPSVSVLSQSEIYPRSRIKTVATIT

Sequences:

>Translated_749_residues
MCLAEGQWLIPTRKETRLLDTAGGSEIKKPGGGRLAEITAAARQKISSASRNVTLSAETLRSGGWRATSWRSLVPGTDVG
LALGVVVLLAILIIPLPTFILDMGLSLSITSSVLVLMVALFLERTLDFTSFPTLLLLTTLLRLSLEIATTRLILSHGSEG
TYAAGHVVAAFGGFLMGGDLFIGGIVFCILLVVNFMVITKGSGRIAEVAARFFLDSMPGKQMAIDADLSSGAINERTARA
KRKELEDESAFYGAMDGAAKFVRGDAIAGLIITAINIVGGLAIGILRHDMPLSEAASTFTTLTVGDGLVSQIPALLVSTA
AGIVVTKGGSDGSTDVTLVRQLGGNPKPLAVAGGLSALFAIMPGLPALPFLVIAVGAGIGAWMRHKTPVKDGDGDVTQIS
PQPTAPPISEMLKLDLLRLELGFGLLPLTSGENPQLTEQIKALRRTVATELGFITPPVRIQDNILLPSDNYVIKLKEIEI
GSGEVKPGKLMAMSPSGGAPDLPGDRTTEPAFGLPAVWIDPSLKPKAVAMKCTIVDPASVIVTHLSEAVRQNLPDLLTYV
ATQTLLDDLPREQQKLVNDLIPSQVPLSTIQRVLQSLLAERVSIRDLPTILESIQEGCSLGLRGVQALTGHVRVRLSRQI
CNALVGGAGYIPMITLSAEWEAEFMAHITGQADDRRLAMPPSMLNKFVGKLREVFNTVSASGEIPVVVVSTPVRDSMRSI
VERVRPSVSVLSQSEIYPRSRIKTVATIT
>Mature_749_residues
MCLAEGQWLIPTRKETRLLDTAGGSEIKKPGGGRLAEITAAARQKISSASRNVTLSAETLRSGGWRATSWRSLVPGTDVG
LALGVVVLLAILIIPLPTFILDMGLSLSITSSVLVLMVALFLERTLDFTSFPTLLLLTTLLRLSLEIATTRLILSHGSEG
TYAAGHVVAAFGGFLMGGDLFIGGIVFCILLVVNFMVITKGSGRIAEVAARFFLDSMPGKQMAIDADLSSGAINERTARA
KRKELEDESAFYGAMDGAAKFVRGDAIAGLIITAINIVGGLAIGILRHDMPLSEAASTFTTLTVGDGLVSQIPALLVSTA
AGIVVTKGGSDGSTDVTLVRQLGGNPKPLAVAGGLSALFAIMPGLPALPFLVIAVGAGIGAWMRHKTPVKDGDGDVTQIS
PQPTAPPISEMLKLDLLRLELGFGLLPLTSGENPQLTEQIKALRRTVATELGFITPPVRIQDNILLPSDNYVIKLKEIEI
GSGEVKPGKLMAMSPSGGAPDLPGDRTTEPAFGLPAVWIDPSLKPKAVAMKCTIVDPASVIVTHLSEAVRQNLPDLLTYV
ATQTLLDDLPREQQKLVNDLIPSQVPLSTIQRVLQSLLAERVSIRDLPTILESIQEGCSLGLRGVQALTGHVRVRLSRQI
CNALVGGAGYIPMITLSAEWEAEFMAHITGQADDRRLAMPPSMLNKFVGKLREVFNTVSASGEIPVVVVSTPVRDSMRSI
VERVRPSVSVLSQSEIYPRSRIKTVATIT

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=668, Percent_Identity=41.3173652694611, Blast_Score=494, Evalue=1e-141,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 79441; Mature: 79441

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLAEGQWLIPTRKETRLLDTAGGSEIKKPGGGRLAEITAAARQKISSASRNVTLSAETL
CCCCCCCEECCCCCHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHH
RSGGWRATSWRSLVPGTDVGLALGVVVLLAILIIPLPTFILDMGLSLSITSSVLVLMVAL
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLERTLDFTSFPTLLLLTTLLRLSLEIATTRLILSHGSEGTYAAGHVVAAFGGFLMGGDL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHH
FIGGIVFCILLVVNFMVITKGSGRIAEVAARFFLDSMPGKQMAIDADLSSGAINERTARA
HHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHH
KRKELEDESAFYGAMDGAAKFVRGDAIAGLIITAINIVGGLAIGILRHDMPLSEAASTFT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
TLTVGDGLVSQIPALLVSTAAGIVVTKGGSDGSTDVTLVRQLGGNPKPLAVAGGLSALFA
EEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHH
IMPGLPALPFLVIAVGAGIGAWMRHKTPVKDGDGDVTQISPQPTAPPISEMLKLDLLRLE
HHCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
LGFGLLPLTSGENPQLTEQIKALRRTVATELGFITPPVRIQDNILLPSDNYVIKLKEIEI
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCEEECCCCEEEEEEEEEC
GSGEVKPGKLMAMSPSGGAPDLPGDRTTEPAFGLPAVWIDPSLKPKAVAMKCTIVDPASV
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECHHHH
IVTHLSEAVRQNLPDLLTYVATQTLLDDLPREQQKLVNDLIPSQVPLSTIQRVLQSLLAE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RVSIRDLPTILESIQEGCSLGLRGVQALTGHVRVRLSRQICNALVGGAGYIPMITLSAEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
EAEFMAHITGQADDRRLAMPPSMLNKFVGKLREVFNTVSASGEIPVVVVSTPVRDSMRSI
CHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
VERVRPSVSVLSQSEIYPRSRIKTVATIT
HHHHCCHHHHHHHHCCCCHHHHCEEEECC
>Mature Secondary Structure
MCLAEGQWLIPTRKETRLLDTAGGSEIKKPGGGRLAEITAAARQKISSASRNVTLSAETL
CCCCCCCEECCCCCHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHH
RSGGWRATSWRSLVPGTDVGLALGVVVLLAILIIPLPTFILDMGLSLSITSSVLVLMVAL
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLERTLDFTSFPTLLLLTTLLRLSLEIATTRLILSHGSEGTYAAGHVVAAFGGFLMGGDL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHH
FIGGIVFCILLVVNFMVITKGSGRIAEVAARFFLDSMPGKQMAIDADLSSGAINERTARA
HHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHH
KRKELEDESAFYGAMDGAAKFVRGDAIAGLIITAINIVGGLAIGILRHDMPLSEAASTFT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
TLTVGDGLVSQIPALLVSTAAGIVVTKGGSDGSTDVTLVRQLGGNPKPLAVAGGLSALFA
EEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHH
IMPGLPALPFLVIAVGAGIGAWMRHKTPVKDGDGDVTQISPQPTAPPISEMLKLDLLRLE
HHCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
LGFGLLPLTSGENPQLTEQIKALRRTVATELGFITPPVRIQDNILLPSDNYVIKLKEIEI
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCEEECCCCEEEEEEEEEC
GSGEVKPGKLMAMSPSGGAPDLPGDRTTEPAFGLPAVWIDPSLKPKAVAMKCTIVDPASV
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECHHHH
IVTHLSEAVRQNLPDLLTYVATQTLLDDLPREQQKLVNDLIPSQVPLSTIQRVLQSLLAE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RVSIRDLPTILESIQEGCSLGLRGVQALTGHVRVRLSRQICNALVGGAGYIPMITLSAEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
EAEFMAHITGQADDRRLAMPPSMLNKFVGKLREVFNTVSASGEIPVVVVSTPVRDSMRSI
CHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
VERVRPSVSVLSQSEIYPRSRIKTVATIT
HHHHCCHHHHHHHHCCCCHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938923; 1732219; 11259647 [H]