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The map label for this gene is clpB [H]

Identifier: 162147426

GI number: 162147426

Start: 1655812

End: 1658355

Strand: Direct

Name: clpB [H]

Synonym: GDI_1642

Alternate gene names: 162147426

Gene position: 1655812-1658355 (Clockwise)

Preceding gene: 162147425

Following gene: 162147427

Centisome position: 41.98

GC content: 67.45

Gene sequence:

>2544_bases
ATGAATATCGAAAAATTCACCGAACGGTCGCGCGGCTTTCTTCAGGCCGCCCAGACGATCGCGGTGCGTGACTATCATCA
GCAACTGACGCCGGAACATCTGCTGAAGGCGCTGCTGGACGACCCGGAAGGGGCGGCGTCCTCGCTGATCCGTGCCGCCG
GTGGGCAGGCACCGGCGGTCCAGGCGGCGGTCGAGGCCGCGCTGGCCAAGGTGCCGCGCGTACAGGGTGGCGGGGCCGGG
CAGCCGCAGGCCACGCCCGACCTCGTCCGCCTGTTGGATGCCGCGCAGACCGCGGCGCAGAAGGCCGGTGACGAATATGT
GGCGCAGGACCGGCTGCTGGTCGCCATCGCCGCGTCGGACACGCCGGCCGGCCGCGCCCTGCGCGACGGCGGTGCCACGG
CGCAGGCGCTGGACAAGGCGGTGGCCGCCATCCGCAAGGGCCGCACCGTGACCAGCGAGAACGCCGAGGCCAGCTTCGAC
GCGCTGAAGAAATACGCCCGCGACGTAACGGAAATCGCCCAGCAGGGCAAGCTGGACCCGGTCATCGGCCGCGACGAGGA
AATCCGTCGCGCGATCCAGGTCCTGGCCCGGCGCAGCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTGGGCAAGA
CCGCGATCGTCGAAGGGCTGGCCCTGCGCATCGTCAACGGCGACGTACCCGAGGCGCTGAAGAACAAGAAGCTGCTGTCG
CTTGATCTCGGGGCGCTGGTGGCCGGCGCGAAGTTCCGCGGCGAGTTCGAGGAACGGCTGAAAGCCGTGCTGAAGGAGAT
CGAAAGCGCCGAGGGGCAGGTCATCCTGTTCATCGACGAGATGCACACCCTCGTCGGCGCCGGCCGCACGGACGGCGCGA
TGGATGCCTCCAACCTGATCAAGCCGGAACTGGCGCGCGGCACCCTGCACTGCATCGGCGCCACGACGTTGGACGAATAC
CGCAAATATATCGAAAAGGACGCGGCCCTCGCCCGGCGCTTCCAGCCGGTCTATGTCGGCGAGCCCTCGGTGCCCGACAC
GATTTCGATCCTGCGCGGCATCAAGGAGAAGTACGAGCTCCATCACGGCGTGCGCATCACCGACAACGCGCTGGTGGCGG
CGGCGACGCTGTCCAACCGCTACATCACCGACCGCTTCCTGCCGGACAAGGCGATCGACCTGGTGGACGAAGCTGCCAGC
CGCCTGCGCATGCAGATCGACAGCAAGCCCGAGGAACTGGACGAACTCGACCGCCGCCTGATCCAGCTCAAGATCGAGCG
CGAGGCGATTCGCAAGGAAGACGACTCCGCCAGTCGGGAACGGCTGGTGAAGCTGGAAGCCGAACTGGCGGACATCGAGG
AAAAATCGAACGCCATGTCTGCGGCGTGGCACGCCGAGAAGGACCGGGTGAACGCAGTCCAGAAGCTGAAGGAACAGCTC
GACCAGGCGCGCTCGGACGTCGAGGTGGCGCAGCGGCGCGGCGATCTGGGGCGGGCGTCGGAACTGATGTACGGCGTCAT
CCCGAACCTGCAGGAGAAGATCGCCCAGGCGCAAGATGAAAACGAAAGCGCGGCCCGCGGGGCCGGCTTGGTCAGCGAGG
CCGTGACCGAAGGCGCATCGCCTCCGTCGTGTCACGCTGGACCGGCGTGCCCGTTGGTGTTGATGCTGGGGGCGAGCGGG
CGAAGCTGCTGGCGGATGGAGGACGAACTGCGCCGCCTGGTGGTGGGCCAGGAACCGGCGCTGAAGGCCGTGGCGAACGC
CGTGCGGCGTGCGCGCGCCGGCCTGCAGGACCCCAACCGGCCGATCGGCTCGTTCCTGTTCCTCGGCCCGACCGGCGTGG
GCAAGACCGAGCTGTGCAAGGCGCTGGCCCGCTTCCTGTTCGATGACGAAAAGGCGCTGCTCCGCGTGAACATGAGCGAG
TTCATGGAAAAGCACGCGGTCTCCCGCCTGATCGGCGCCCCCCCGGGCTATGTCGGGTATGAGGAGGGCGGCGTCCTGAC
CGAGGCCGCGCGCCGCCGGCCTTATCAGGTGATCCTGTTCGACGAGGTGGAGAAAGCGCACGAGGATGTCTTCAACGTCC
TGCTGCAGGTGCTTGATGACGGCCGCCTGACGGACGGGCAGGGGCGGACGGTCGATTTCCGCAACACCATCATCGTCCTG
ACCAGCAACCTGGGGTCCGATGTCCTGGCCCATCTGCCGGAAACGAATCGACGGAAATGGCTGCCGCACAACGAATCGAC
GGAAATCGGGCGCACTTCCGGCCGGAAGTCCTCAAGGGCGCATTTCCGGCCATCCTGTCCCAACGCCTGCAGCGCGATCA
TCCTGTTCGCACGCCTGATATCCGCATCGCGCGCCTGCACAAGCTACAGCAAGACCGCCAGACTGCGCAAGCCCCTGGAA
GACCGGCACATCTGTGGCGCCCCGAATAAACCTACCACCCGGTCGCTGGCGCGCGGCCGCTACGACCCGGTCTACAGCGC
GCGGCGCAGAACCCGGGGGCCCCAGCGCTGCTTGCAGGCACCATCCGCCGGGGCGCTGCTGTAA

Upstream 100 bases:

>100_bases
CATTATCCCCATCTCGGATCTGTCGCCGGGTCTGCCATTGCCTCTTCAGGGATGGCGTTTCCCGGCCTTCAGGTCGCCTG
AGTGAAAGGGACATGGGATT

Downstream 100 bases:

>100_bases
AGCACCAGCCGGATGAGCGAGACCGTAAAGGCAACGGCCGATCAAGCCCGCCTGACCATCAATGGCCGCTCGATCGCGGA
GGTCTGAAACCGGTGGGGGG

Product: chaperone clpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 847

Protein sequence:

>847_residues
MNIEKFTERSRGFLQAAQTIAVRDYHQQLTPEHLLKALLDDPEGAASSLIRAAGGQAPAVQAAVEAALAKVPRVQGGGAG
QPQATPDLVRLLDAAQTAAQKAGDEYVAQDRLLVAIAASDTPAGRALRDGGATAQALDKAVAAIRKGRTVTSENAEASFD
ALKKYARDVTEIAQQGKLDPVIGRDEEIRRAIQVLARRSKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKNKKLLS
LDLGALVAGAKFRGEFEERLKAVLKEIESAEGQVILFIDEMHTLVGAGRTDGAMDASNLIKPELARGTLHCIGATTLDEY
RKYIEKDAALARRFQPVYVGEPSVPDTISILRGIKEKYELHHGVRITDNALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQIDSKPEELDELDRRLIQLKIEREAIRKEDDSASRERLVKLEAELADIEEKSNAMSAAWHAEKDRVNAVQKLKEQL
DQARSDVEVAQRRGDLGRASELMYGVIPNLQEKIAQAQDENESAARGAGLVSEAVTEGASPPSCHAGPACPLVLMLGASG
RSCWRMEDELRRLVVGQEPALKAVANAVRRARAGLQDPNRPIGSFLFLGPTGVGKTELCKALARFLFDDEKALLRVNMSE
FMEKHAVSRLIGAPPGYVGYEEGGVLTEAARRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFRNTIIVL
TSNLGSDVLAHLPETNRRKWLPHNESTEIGRTSGRKSSRAHFRPSCPNACSAIILFARLISASRACTSYSKTARLRKPLE
DRHICGAPNKPTTRSLARGRYDPVYSARRRTRGPQRCLQAPSAGALL

Sequences:

>Translated_847_residues
MNIEKFTERSRGFLQAAQTIAVRDYHQQLTPEHLLKALLDDPEGAASSLIRAAGGQAPAVQAAVEAALAKVPRVQGGGAG
QPQATPDLVRLLDAAQTAAQKAGDEYVAQDRLLVAIAASDTPAGRALRDGGATAQALDKAVAAIRKGRTVTSENAEASFD
ALKKYARDVTEIAQQGKLDPVIGRDEEIRRAIQVLARRSKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKNKKLLS
LDLGALVAGAKFRGEFEERLKAVLKEIESAEGQVILFIDEMHTLVGAGRTDGAMDASNLIKPELARGTLHCIGATTLDEY
RKYIEKDAALARRFQPVYVGEPSVPDTISILRGIKEKYELHHGVRITDNALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQIDSKPEELDELDRRLIQLKIEREAIRKEDDSASRERLVKLEAELADIEEKSNAMSAAWHAEKDRVNAVQKLKEQL
DQARSDVEVAQRRGDLGRASELMYGVIPNLQEKIAQAQDENESAARGAGLVSEAVTEGASPPSCHAGPACPLVLMLGASG
RSCWRMEDELRRLVVGQEPALKAVANAVRRARAGLQDPNRPIGSFLFLGPTGVGKTELCKALARFLFDDEKALLRVNMSE
FMEKHAVSRLIGAPPGYVGYEEGGVLTEAARRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFRNTIIVL
TSNLGSDVLAHLPETNRRKWLPHNESTEIGRTSGRKSSRAHFRPSCPNACSAIILFARLISASRACTSYSKTARLRKPLE
DRHICGAPNKPTTRSLARGRYDPVYSARRRTRGPQRCLQAPSAGALL
>Mature_847_residues
MNIEKFTERSRGFLQAAQTIAVRDYHQQLTPEHLLKALLDDPEGAASSLIRAAGGQAPAVQAAVEAALAKVPRVQGGGAG
QPQATPDLVRLLDAAQTAAQKAGDEYVAQDRLLVAIAASDTPAGRALRDGGATAQALDKAVAAIRKGRTVTSENAEASFD
ALKKYARDVTEIAQQGKLDPVIGRDEEIRRAIQVLARRSKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKNKKLLS
LDLGALVAGAKFRGEFEERLKAVLKEIESAEGQVILFIDEMHTLVGAGRTDGAMDASNLIKPELARGTLHCIGATTLDEY
RKYIEKDAALARRFQPVYVGEPSVPDTISILRGIKEKYELHHGVRITDNALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMQIDSKPEELDELDRRLIQLKIEREAIRKEDDSASRERLVKLEAELADIEEKSNAMSAAWHAEKDRVNAVQKLKEQL
DQARSDVEVAQRRGDLGRASELMYGVIPNLQEKIAQAQDENESAARGAGLVSEAVTEGASPPSCHAGPACPLVLMLGASG
RSCWRMEDELRRLVVGQEPALKAVANAVRRARAGLQDPNRPIGSFLFLGPTGVGKTELCKALARFLFDDEKALLRVNMSE
FMEKHAVSRLIGAPPGYVGYEEGGVLTEAARRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFRNTIIVL
TSNLGSDVLAHLPETNRRKWLPHNESTEIGRTSGRKSSRAHFRPSCPNACSAIILFARLISASRACTSYSKTARLRKPLE
DRHICGAPNKPTTRSLARGRYDPVYSARRRTRGPQRCLQAPSAGALL

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=166, Percent_Identity=48.7951807228916, Blast_Score=180, Evalue=5e-45,
Organism=Escherichia coli, GI1788943, Length=847, Percent_Identity=54.1912632821724, Blast_Score=882, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=398, Percent_Identity=42.2110552763819, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=690, Percent_Identity=51.304347826087, Blast_Score=667, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=788, Percent_Identity=42.7664974619289, Blast_Score=595, Evalue=1e-171,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 92293; Mature: 92293

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEKFTERSRGFLQAAQTIAVRDYHQQLTPEHLLKALLDDPEGAASSLIRAAGGQAPAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCHHH
QAAVEAALAKVPRVQGGGAGQPQATPDLVRLLDAAQTAAQKAGDEYVAQDRLLVAIAASD
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCC
TPAGRALRDGGATAQALDKAVAAIRKGRTVTSENAEASFDALKKYARDVTEIAQQGKLDP
CCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDEEIRRAIQVLARRSKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKNKKLLS
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCHHHHHCCCEEE
LDLGALVAGAKFRGEFEERLKAVLKEIESAEGQVILFIDEMHTLVGAGRTDGAMDASNLI
EEHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHCC
KPELARGTLHCIGATTLDEYRKYIEKDAALARRFQPVYVGEPSVPDTISILRGIKEKYEL
CCHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHH
HHGVRITDNALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMQIDSKPEELDELDRRL
HCCEEEECCCEEEHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IQLKIEREAIRKEDDSASRERLVKLEAELADIEEKSNAMSAAWHAEKDRVNAVQKLKEQL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQARSDVEVAQRRGDLGRASELMYGVIPNLQEKIAQAQDENESAARGAGLVSEAVTEGAS
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
PPSCHAGPACPLVLMLGASGRSCWRMEDELRRLVVGQEPALKAVANAVRRARAGLQDPNR
CCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
PIGSFLFLGPTGVGKTELCKALARFLFDDEKALLRVNMSEFMEKHAVSRLIGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHEECHHHHHHHHHHHHHHCCCCCCCCC
EEGGVLTEAARRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFRNTIIVL
CCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNLGSDVLAHLPETNRRKWLPHNESTEIGRTSGRKSSRAHFRPSCPNACSAIILFARLI
ECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SASRACTSYSKTARLRKPLEDRHICGAPNKPTTRSLARGRYDPVYSARRRTRGPQRCLQA
HHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHCC
PSAGALL
CCCCCCC
>Mature Secondary Structure
MNIEKFTERSRGFLQAAQTIAVRDYHQQLTPEHLLKALLDDPEGAASSLIRAAGGQAPAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCHHH
QAAVEAALAKVPRVQGGGAGQPQATPDLVRLLDAAQTAAQKAGDEYVAQDRLLVAIAASD
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCC
TPAGRALRDGGATAQALDKAVAAIRKGRTVTSENAEASFDALKKYARDVTEIAQQGKLDP
CCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDEEIRRAIQVLARRSKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPEALKNKKLLS
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCHHHHHCCCEEE
LDLGALVAGAKFRGEFEERLKAVLKEIESAEGQVILFIDEMHTLVGAGRTDGAMDASNLI
EEHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHCC
KPELARGTLHCIGATTLDEYRKYIEKDAALARRFQPVYVGEPSVPDTISILRGIKEKYEL
CCHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHH
HHGVRITDNALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMQIDSKPEELDELDRRL
HCCEEEECCCEEEHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IQLKIEREAIRKEDDSASRERLVKLEAELADIEEKSNAMSAAWHAEKDRVNAVQKLKEQL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQARSDVEVAQRRGDLGRASELMYGVIPNLQEKIAQAQDENESAARGAGLVSEAVTEGAS
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
PPSCHAGPACPLVLMLGASGRSCWRMEDELRRLVVGQEPALKAVANAVRRARAGLQDPNR
CCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
PIGSFLFLGPTGVGKTELCKALARFLFDDEKALLRVNMSEFMEKHAVSRLIGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHEECHHHHHHHHHHHHHHCCCCCCCCC
EEGGVLTEAARRRPYQVILFDEVEKAHEDVFNVLLQVLDDGRLTDGQGRTVDFRNTIIVL
CCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNLGSDVLAHLPETNRRKWLPHNESTEIGRTSGRKSSRAHFRPSCPNACSAIILFARLI
ECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SASRACTSYSKTARLRKPLEDRHICGAPNKPTTRSLARGRYDPVYSARRRTRGPQRCLQA
HHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHCC
PSAGALL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA