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The map label for this gene is yrpG [H]

Identifier: 162147424

GI number: 162147424

Start: 1654030

End: 1655094

Strand: Direct

Name: yrpG [H]

Synonym: GDI_1640

Alternate gene names: 162147424

Gene position: 1654030-1655094 (Clockwise)

Preceding gene: 162147422

Following gene: 162147425

Centisome position: 41.94

GC content: 67.32

Gene sequence:

>1065_bases
ATGCACTATCGCCAGCTCGGCCGTTCCGGCTTGCGCGTATCCGTCTTCACTCTCGGCACGATGACGTTCGGCGGCAAGGG
TGCCTTCGCCAAGACGGGCAGCACCGATGTCGCCGGCGCGAAGCGGCAGATCGACATGTGCATCGAAGCCGGCATCAACA
TGTTCGATACCGCCGACGTCTATTCCTCCGGCGTGTCCGAGGAAATCCTGGGCGAGGCGCTGAAGGGCCGGGCGGGGGAA
ATCCTGGTGGGCACCAAGGCGCGCTTTCCCATGGGCAAGGGACAGAACGACGCCGGCTCGTCCCGCTATCACCTGATATC
GGCGGCGGAAGCCAGCCTGCGCCGCCTCGGCCGCGACCATATCGACCTGTTCTACCTGCATGAATGGGACGGCCAGACCC
CGCTGGACGAAACGCTGGAGGCGCTGGACACCCTGACCCGCGCGGGCAAGATCCGCTATGCCGGCGTGTCCAATTTCTCC
GCCTGGCACATCATGAAGGCGCTCAGCACGGCGGAACGCCATCGCCTGATCGCCCCGGTGTCGCAGCAGATCTATTATTC
GCTGCAGGCGCGCGAGGCCGAATACGAACTCCTGCCGCTCGCGCTCGACCAGGGGATCGGCGTGCAGGTCTGGAGCCCGA
TGGCCGGAGGCCTGCTGTCCGGCAAGCACCGGCGCGGCAAGCCCGAACCCGAGGGCACGCGCCAGCTCGCGCAATGGAAC
GAACCGCCGGTCTATGACGTGGAAAAGCTCTACGATGTCGTCGAAGTCCTGGTGGCGATCGGCGCGGAACGCGGCGTGTC
CGCCGCCCAGGTCGCGCTGGCCTGGGTCGCGCATCGTCCTGCGATCACCTCGGTGGTGATCGGGGCGCGGACCGACGCGC
AACTGGCCGATAACCTCAAGGCGGCGGAACTCAGCCTGTCGGCCGAGGAAATGGCCCGGCTGGACGAGGCCAGCGCGCCG
CCGCTGCTCTATCCGTACTGGCATCAGGCCAGCACGGCGTCGGACCGCCTGTCGCCGGCCGACCTGCTGCTGCTCGGCCC
CGCGATCGACAGGAAGAAGGGCTGA

Upstream 100 bases:

>100_bases
CCTTCGCCCTTTCCGGAAACTGTTTTCCGGATTCGACGGTTATCATTCCCCGGTGCGGGCGCCCATAGTTCCGCGCAATC
AATCTGACGGGAGACAGTCC

Downstream 100 bases:

>100_bases
TCGCGCGTGGCGCGGCGCCAGGTCGCGGTGGCGGCATGCGCCGTCCTGCTGGCCGTTTCCCCGGCCCGGGCCGGGGAAAC
CGGTATTATCACCACCCAGA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MHYRQLGRSGLRVSVFTLGTMTFGGKGAFAKTGSTDVAGAKRQIDMCIEAGINMFDTADVYSSGVSEEILGEALKGRAGE
ILVGTKARFPMGKGQNDAGSSRYHLISAAEASLRRLGRDHIDLFYLHEWDGQTPLDETLEALDTLTRAGKIRYAGVSNFS
AWHIMKALSTAERHRLIAPVSQQIYYSLQAREAEYELLPLALDQGIGVQVWSPMAGGLLSGKHRRGKPEPEGTRQLAQWN
EPPVYDVEKLYDVVEVLVAIGAERGVSAAQVALAWVAHRPAITSVVIGARTDAQLADNLKAAELSLSAEEMARLDEASAP
PLLYPYWHQASTASDRLSPADLLLLGPAIDRKKG

Sequences:

>Translated_354_residues
MHYRQLGRSGLRVSVFTLGTMTFGGKGAFAKTGSTDVAGAKRQIDMCIEAGINMFDTADVYSSGVSEEILGEALKGRAGE
ILVGTKARFPMGKGQNDAGSSRYHLISAAEASLRRLGRDHIDLFYLHEWDGQTPLDETLEALDTLTRAGKIRYAGVSNFS
AWHIMKALSTAERHRLIAPVSQQIYYSLQAREAEYELLPLALDQGIGVQVWSPMAGGLLSGKHRRGKPEPEGTRQLAQWN
EPPVYDVEKLYDVVEVLVAIGAERGVSAAQVALAWVAHRPAITSVVIGARTDAQLADNLKAAELSLSAEEMARLDEASAP
PLLYPYWHQASTASDRLSPADLLLLGPAIDRKKG
>Mature_354_residues
MHYRQLGRSGLRVSVFTLGTMTFGGKGAFAKTGSTDVAGAKRQIDMCIEAGINMFDTADVYSSGVSEEILGEALKGRAGE
ILVGTKARFPMGKGQNDAGSSRYHLISAAEASLRRLGRDHIDLFYLHEWDGQTPLDETLEALDTLTRAGKIRYAGVSNFS
AWHIMKALSTAERHRLIAPVSQQIYYSLQAREAEYELLPLALDQGIGVQVWSPMAGGLLSGKHRRGKPEPEGTRQLAQWN
EPPVYDVEKLYDVVEVLVAIGAERGVSAAQVALAWVAHRPAITSVVIGARTDAQLADNLKAAELSLSAEEMARLDEASAP
PLLYPYWHQASTASDRLSPADLLLLGPAIDRKKG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=35.8974358974359, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=35.8974358974359, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=35.5769230769231, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI27436969, Length=313, Percent_Identity=35.1437699680511, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=35.048231511254, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI27436971, Length=312, Percent_Identity=33.0128205128205, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI223718702, Length=274, Percent_Identity=33.2116788321168, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI41152114, Length=273, Percent_Identity=31.8681318681319, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI41327764, Length=304, Percent_Identity=30.5921052631579, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI223718708, Length=141, Percent_Identity=36.1702127659575, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=36.7781155015198, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=30.4878048780488, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=31.0144927536232, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788070, Length=322, Percent_Identity=34.472049689441, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1788081, Length=274, Percent_Identity=32.4817518248175, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI48994888, Length=288, Percent_Identity=25.6944444444444, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=342, Percent_Identity=29.8245614035088, Blast_Score=159, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6323998, Length=319, Percent_Identity=28.8401253918495, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=28.135593220339, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=332, Percent_Identity=26.5060240963855, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=26.5625, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=32.2784810126582, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=25.7142857142857, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45549126, Length=337, Percent_Identity=26.1127596439169, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=30.03003003003, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24646159, Length=232, Percent_Identity=30.6034482758621, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644950, Length=304, Percent_Identity=27.3026315789474, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38397; Mature: 38397

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYRQLGRSGLRVSVFTLGTMTFGGKGAFAKTGSTDVAGAKRQIDMCIEAGINMFDTADV
CCHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECHHH
YSSGVSEEILGEALKGRAGEILVGTKARFPMGKGQNDAGSSRYHLISAAEASLRRLGRDH
HHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCC
IDLFYLHEWDGQTPLDETLEALDTLTRAGKIRYAGVSNFSAWHIMKALSTAERHRLIAPV
EEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SQQIYYSLQAREAEYELLPLALDQGIGVQVWSPMAGGLLSGKHRRGKPEPEGTRQLAQWN
HHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHCCHHCCCCCCCCCCCHHHHHHHCCC
EPPVYDVEKLYDVVEVLVAIGAERGVSAAQVALAWVAHRPAITSVVIGARTDAQLADNLK
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHCCH
AAELSLSAEEMARLDEASAPPLLYPYWHQASTASDRLSPADLLLLGPAIDRKKG
HHHHCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MHYRQLGRSGLRVSVFTLGTMTFGGKGAFAKTGSTDVAGAKRQIDMCIEAGINMFDTADV
CCHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECHHH
YSSGVSEEILGEALKGRAGEILVGTKARFPMGKGQNDAGSSRYHLISAAEASLRRLGRDH
HHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCC
IDLFYLHEWDGQTPLDETLEALDTLTRAGKIRYAGVSNFSAWHIMKALSTAERHRLIAPV
EEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SQQIYYSLQAREAEYELLPLALDQGIGVQVWSPMAGGLLSGKHRRGKPEPEGTRQLAQWN
HHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHCCHHCCCCCCCCCCCHHHHHHHCCC
EPPVYDVEKLYDVVEVLVAIGAERGVSAAQVALAWVAHRPAITSVVIGARTDAQLADNLK
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHCCH
AAELSLSAEEMARLDEASAPPLLYPYWHQASTASDRLSPADLLLLGPAIDRKKG
HHHHCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]