Click here to switch to the map view.

The map label for this gene is 162147396

Identifier: 162147396

GI number: 162147396

Start: 1616745

End: 1618433

Strand: Direct

Name: 162147396

Synonym: GDI_1611

Alternate gene names: NA

Gene position: 1616745-1618433 (Clockwise)

Preceding gene: 162147395

Following gene: 162147400

Centisome position: 40.99

GC content: 70.4

Gene sequence:

>1689_bases
ATGCGTTCCATGCCCCCCCATCGTCCGCGCGCCGCCCTTGTATCCGCCATGCTTCTGGCGGCGGCGTCCCCCGCGCATGC
CGCGTCCCCGTGGGCGCCGATCGACCCCGGCCGCATGTCGGCCACCATCCGCACGCTGGCGTCCGACGCGTTCGCCGGGC
GCGCGCCCGCCACGGCCGGTGAGGCGAAGACCGTGGACTGGCTGATCGCCCAGTATCGCGACATCGGGCTGGAACCCGGT
GGCGAGAATGGCGGCTGGACGCAGAGCGTACCGCTGCTGCGGACCCGGATCGGCACCCCGGCCCGGCTGGACGCCACCAT
CAACGGGGCGCCGATGGCGCTGGAGCTGAAGAAGGACATCTACCTGACCACCCTGTCGCCGGTCACACGCATCAGGGTGG
ACGCGGCGCCGATGGTCTTCGTGGGGTACGGCGTGAACGCGCCCGAACGCCATTGGGACGATTACAAGGGCGTGGACCTG
AAGGGAAAAGTTGCCGTCTTCCTCATCAACGATCCGGATTTCGACGCCAGACCGGGCGAGGCGGTGGCCGGACGGTTCGG
CGGCCGGACGATGACCTATTACGGCCGCTGGACCTACAAATACGAGGAAGCGGCCCGACGCGGTGCCATCGCCGCCCTGA
TCGTGCATGACACGCCGGGCGCGTCCTATCCATGGACCACGGTCATCGCGCCGGGCGGCGAGGCCTTCGACATCGTGCGG
CAGGGCGATGCGAACAAGCCGGTGCCGCTGCAAGGCTGGCTGGAGGGCGACGCCGCGCACCGCCTGTTCGCCCGCGCGGG
GCTGGACCTTGCGGCGCTGCGCGTGAAGGCGCGCGACCCGGATTTCCATCCGGTCACGCTGCCCGGTACGACCCTGACGG
CAGACCTGCCGGTCGAAACCGCGACATTGCAGAGCCGCAACGTGATCGGCAAGCTGACCGGCGCCCGCCATCCCGACGAG
ACGGTCATGTACGGGGCCCACTGGGACGCATTCGGCGTCGGCACGGACGCACAGGGCCGGCAGGTGATCCGGCACGGCGC
CGTGGATGACGGATCGGGAATTGCCGCGATCCTGGAAATTGCCCGCGCGTTCAAGGCCGGGCATCGGCCGGACCGGACGG
TCCTGTTCGCCGCCTGGACCGCCGAGGAACGCGGGCTGCTGGGTTCGACGTGGTATGCCGCCCACCCGCTGGCACCACTG
GCCAGGACAGCGGCGAACTTCACCATCGACGTCCTGCAGACCGCCGGCCCGGCCCATAATGCCTTCATCATCGGCGCGGG
ACAGGACACGTTGCAGGACGACCTGACGGAAGCCGCCCGCGCGCAGGGACGCGTCACGCAGCCCGAGGCCAGGCCCGAAC
GCGGTGCCTTCTACCGCGCCGACCACCTGCCCTTCGCCCATGCCGGCGTGCCCGTCGTGGCCATCATGGGCATGGCCGGC
CCCTACGACCTGCTGTCCGGCGGCATCCCGGCCGGCGCGGCATGGCTGAAGGCCTACGCCGCCTGTTATCACCAGCCCTG
CGACACCTGGGACCTGCACTGGGACCTGCGCGGCGCGGCGGAAGATGCCGCCCTGGTCTATCAGGTCGGCCGGACCGTCG
CGTTCTCGCACACCTGGCCCCAGTGGAAACCCGGATCGGAATTCGCCGGCATTCGCGCGGCGAGCGCGGCCGAGCGAAGC
GATCCGTAG

Upstream 100 bases:

>100_bases
CGACCTGTTCGGCGCCGCCTGAAACGGGTGGCGGCCAGGCTTGCCGCCCGCGTCAATGCGGATAGTCTGCCCGGTATCCT
GCCCCGCAGCCTGATCGGAA

Downstream 100 bases:

>100_bases
AACAAACCCTATCGCCCCGGCTCGGCATACTCCCATCCCCCGCCAAGCGCACGATACAGGGCCACGAGCGTGGTTTCCGA
GCGTGTCTGGCTGTCGGCAA

Product: aminopeptidase

Products: NA

Alternate protein names: SGAP [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MRSMPPHRPRAALVSAMLLAAASPAHAASPWAPIDPGRMSATIRTLASDAFAGRAPATAGEAKTVDWLIAQYRDIGLEPG
GENGGWTQSVPLLRTRIGTPARLDATINGAPMALELKKDIYLTTLSPVTRIRVDAAPMVFVGYGVNAPERHWDDYKGVDL
KGKVAVFLINDPDFDARPGEAVAGRFGGRTMTYYGRWTYKYEEAARRGAIAALIVHDTPGASYPWTTVIAPGGEAFDIVR
QGDANKPVPLQGWLEGDAAHRLFARAGLDLAALRVKARDPDFHPVTLPGTTLTADLPVETATLQSRNVIGKLTGARHPDE
TVMYGAHWDAFGVGTDAQGRQVIRHGAVDDGSGIAAILEIARAFKAGHRPDRTVLFAAWTAEERGLLGSTWYAAHPLAPL
ARTAANFTIDVLQTAGPAHNAFIIGAGQDTLQDDLTEAARAQGRVTQPEARPERGAFYRADHLPFAHAGVPVVAIMGMAG
PYDLLSGGIPAGAAWLKAYAACYHQPCDTWDLHWDLRGAAEDAALVYQVGRTVAFSHTWPQWKPGSEFAGIRAASAAERS
DP

Sequences:

>Translated_562_residues
MRSMPPHRPRAALVSAMLLAAASPAHAASPWAPIDPGRMSATIRTLASDAFAGRAPATAGEAKTVDWLIAQYRDIGLEPG
GENGGWTQSVPLLRTRIGTPARLDATINGAPMALELKKDIYLTTLSPVTRIRVDAAPMVFVGYGVNAPERHWDDYKGVDL
KGKVAVFLINDPDFDARPGEAVAGRFGGRTMTYYGRWTYKYEEAARRGAIAALIVHDTPGASYPWTTVIAPGGEAFDIVR
QGDANKPVPLQGWLEGDAAHRLFARAGLDLAALRVKARDPDFHPVTLPGTTLTADLPVETATLQSRNVIGKLTGARHPDE
TVMYGAHWDAFGVGTDAQGRQVIRHGAVDDGSGIAAILEIARAFKAGHRPDRTVLFAAWTAEERGLLGSTWYAAHPLAPL
ARTAANFTIDVLQTAGPAHNAFIIGAGQDTLQDDLTEAARAQGRVTQPEARPERGAFYRADHLPFAHAGVPVVAIMGMAG
PYDLLSGGIPAGAAWLKAYAACYHQPCDTWDLHWDLRGAAEDAALVYQVGRTVAFSHTWPQWKPGSEFAGIRAASAAERS
DP
>Mature_562_residues
MRSMPPHRPRAALVSAMLLAAASPAHAASPWAPIDPGRMSATIRTLASDAFAGRAPATAGEAKTVDWLIAQYRDIGLEPG
GENGGWTQSVPLLRTRIGTPARLDATINGAPMALELKKDIYLTTLSPVTRIRVDAAPMVFVGYGVNAPERHWDDYKGVDL
KGKVAVFLINDPDFDARPGEAVAGRFGGRTMTYYGRWTYKYEEAARRGAIAALIVHDTPGASYPWTTVIAPGGEAFDIVR
QGDANKPVPLQGWLEGDAAHRLFARAGLDLAALRVKARDPDFHPVTLPGTTLTADLPVETATLQSRNVIGKLTGARHPDE
TVMYGAHWDAFGVGTDAQGRQVIRHGAVDDGSGIAAILEIARAFKAGHRPDRTVLFAAWTAEERGLLGSTWYAAHPLAPL
ARTAANFTIDVLQTAGPAHNAFIIGAGQDTLQDDLTEAARAQGRVTQPEARPERGAFYRADHLPFAHAGVPVVAIMGMAG
PYDLLSGGIPAGAAWLKAYAACYHQPCDTWDLHWDLRGAAEDAALVYQVGRTVAFSHTWPQWKPGSEFAGIRAASAAERS
DP

Specific function: Specific for larger hydrophobic acids, especially leucine. No cleavage occurs if the next residue is proline [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28A subfamily [H]

Homologues:

Organism=Homo sapiens, GI57232740, Length=114, Percent_Identity=38.5964912280702, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI301500668, Length=91, Percent_Identity=46.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4758398, Length=91, Percent_Identity=46.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI301500666, Length=91, Percent_Identity=46.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI62548858, Length=91, Percent_Identity=46.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4885505, Length=98, Percent_Identity=40.8163265306122, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI301500670, Length=91, Percent_Identity=46.1538461538462, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24308545, Length=91, Percent_Identity=45.0549450549451, Blast_Score=66, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71984813, Length=321, Percent_Identity=25.2336448598131, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71995324, Length=220, Percent_Identity=29.5454545454545, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25147314, Length=220, Percent_Identity=29.5454545454545, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995331, Length=220, Percent_Identity=29.5454545454545, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484 [H]

Pfam domain/function: PF04389 Peptidase_M28 [H]

EC number: =3.4.11.24 [H]

Molecular weight: Translated: 60109; Mature: 60109

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSMPPHRPRAALVSAMLLAAASPAHAASPWAPIDPGRMSATIRTLASDAFAGRAPATAG
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
EAKTVDWLIAQYRDIGLEPGGENGGWTQSVPLLRTRIGTPARLDATINGAPMALELKKDI
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEEEECCE
YLTTLSPVTRIRVDAAPMVFVGYGVNAPERHWDDYKGVDLKGKVAVFLINDPDFDARPGE
EEEECCCCEEEEECCCCEEEEECCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCH
AVAGRFGGRTMTYYGRWTYKYEEAARRGAIAALIVHDTPGASYPWTTVIAPGGEAFDIVR
HHHHCCCCEEEEEEEEEEEEHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCEEEHEE
QGDANKPVPLQGWLEGDAAHRLFARAGLDLAALRVKARDPDFHPVTLPGTTLTADLPVET
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCEEEECCCCEE
ATLQSRNVIGKLTGARHPDETVMYGAHWDAFGVGTDAQGRQVIRHGAVDDGSGIAAILEI
EHHCCCCHHEECCCCCCCCCEEEEECCCCCEECCCCCCCHHHHHHCCCCCCCCHHHHHHH
ARAFKAGHRPDRTVLFAAWTAEERGLLGSTWYAAHPLAPLARTAANFTIDVLQTAGPAHN
HHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCHHHHHHHCCCEEEEECCCCCCCC
AFIIGAGQDTLQDDLTEAARAQGRVTQPEARPERGAFYRADHLPFAHAGVPVVAIMGMAG
EEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCC
PYDLLSGGIPAGAAWLKAYAACYHQPCDTWDLHWDLRGAAEDAALVYQVGRTVAFSHTWP
CHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHCCEEEEECCCC
QWKPGSEFAGIRAASAAERSDP
CCCCCCCCCCCEECCCHHCCCC
>Mature Secondary Structure
MRSMPPHRPRAALVSAMLLAAASPAHAASPWAPIDPGRMSATIRTLASDAFAGRAPATAG
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
EAKTVDWLIAQYRDIGLEPGGENGGWTQSVPLLRTRIGTPARLDATINGAPMALELKKDI
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEEEECCE
YLTTLSPVTRIRVDAAPMVFVGYGVNAPERHWDDYKGVDLKGKVAVFLINDPDFDARPGE
EEEECCCCEEEEECCCCEEEEECCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCH
AVAGRFGGRTMTYYGRWTYKYEEAARRGAIAALIVHDTPGASYPWTTVIAPGGEAFDIVR
HHHHCCCCEEEEEEEEEEEEHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCCEEEHEE
QGDANKPVPLQGWLEGDAAHRLFARAGLDLAALRVKARDPDFHPVTLPGTTLTADLPVET
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCEEEECCCCEE
ATLQSRNVIGKLTGARHPDETVMYGAHWDAFGVGTDAQGRQVIRHGAVDDGSGIAAILEI
EHHCCCCHHEECCCCCCCCCEEEEECCCCCEECCCCCCCHHHHHHCCCCCCCCHHHHHHH
ARAFKAGHRPDRTVLFAAWTAEERGLLGSTWYAAHPLAPLARTAANFTIDVLQTAGPAHN
HHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCHHHHHHHCCCEEEEECCCCCCCC
AFIIGAGQDTLQDDLTEAARAQGRVTQPEARPERGAFYRADHLPFAHAGVPVVAIMGMAG
EEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCC
PYDLLSGGIPAGAAWLKAYAACYHQPCDTWDLHWDLRGAAEDAALVYQVGRTVAFSHTWP
CHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHCCEEEEECCCC
QWKPGSEFAGIRAASAAERSDP
CCCCCCCCCCCEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8665903; 2503378; 8444149; 9048953 [H]