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The map label for this gene is cusC [H]

Identifier: 162147390

GI number: 162147390

Start: 1606624

End: 1608147

Strand: Direct

Name: cusC [H]

Synonym: GDI_1605

Alternate gene names: 162147390

Gene position: 1606624-1608147 (Clockwise)

Preceding gene: 162147389

Following gene: 162147391

Centisome position: 40.73

GC content: 70.28

Gene sequence:

>1524_bases
ATGAGCATGAAGACGAGACGCACATTCCACCGGGCCGGGCTGATGCTGCTGGCCGCCACGATGCTGGCGGGGTGCACGGT
GGGGCCGCGCTACCAGCCGGACCGGATGAAGCTGCCGCCGGGCTTTGCCGAGGACGAGCATGCCGCGACGCCGGCGGAAA
TCGCCCGCACCAATGCCGAGCTGAAGGACTGGTGGCACCGCTTCGGCGACGCCGAGCTGGACCGGCTGGTCGACCGGGCG
ATCGCGGGCAATTACGACCTGCAGATCGCCGGCCAGCGCATCCTGGCCGAGCGCGCGCTGCGCGACGTCCAGGCCTCCGC
CTGGTATCCGCAGGTCGATGCCAACACCACCGACGGTGACAGCCGCTATTCCATCAACGTGGACAACTGGCCGCTGCGCC
CGGGCAATCCGGCCAACCGGCCGGGGGCGTCGTACCTGTCCTACGGCGTCAGCGCCAGCTGGCAGATCGACGTGTTCGGC
CGCATCCGCCGCGCGGTCGAGGCCTCGGAACACGCGGTCGAGGAGAATGTCGAGGAACGGCGCGCGGTGCTGATGACCAT
GCTGTCGTCGCTGGTCAGCGACTACATGGTGCTGCGCGACACCCAGCTGCGGCTGGAGATCTCGAACCGCAACATCGGGG
TGGCGCAGGAAGCCTACGACCTGACGCGGCGGCTGTATCTGGAGGGCGTGGGCAACACGCTGCAGATCGCCCAGGCGAAG
GCCGAGCTGGACGCCCAGCAGGCGGCGCGCGAGCCGCTGCGCACCCATATCGCGCAGATCACCCACGCCATCGACGTGCT
GATGGGCCAGGTGCCCGGCACCACCGAGGCCGAACTGAAGGTGGCGCGGCCGCTGCCCCAGGTGCCGGAATTCCCGGCGA
CGGTGCCCTCGATCGTGCTGGGCAACCGGCCCGACATCCGCCGCGCCGAGCGCGCCTATGCCGAGGCGACGGCGCGGATC
GGGGTGGCGGTGGCGCAGATGTATCCGAATTTCGCCATTCCGCTGAACTTCAACCCCAACGCGTCGGCGATGTACCAGGT
GTTCGAGGCCGGGGCGCTGAGCTGGCAGTTCTTCATGCTGGCGTCGCTGCCGCTGATGCATGGCGGCAAGCTGACCGGGC
AGATCCGCGCCGCCCAGGCGGCGGCGGAAGCCAGCCGCCTGACCTACCGCCAGACGGTGCTGGGCGCGTTCCGCGAGGTC
GAGGACGCGATGGCGGCGTGGCATGACGACGTGGAGCACACCGAACTGCTGCACCGCGCCGCCGAGGACAGCCGGCTGGC
CAGCGACCGGGCGCGCAAGCTGTATGCCGCCGGGCTGGTGGGCTTCCTGGAGGTGCTGACCACCGAGCGCACCGCCCTGG
CCGCCGAGAACGCCGAGGCCGTGGCGCGGCTGGAACGCCTGCAGGATGCCATCGACCTCTATACCGCCATGGGTGCCGGC
TGGCAGGGCGTGGGGGTGACCGCCTCCGCCCTGCCGGTGTCGCTGGAGAAGCAGAACGTCCTGGCGCGGGCGTTCCAGGA
TTGA

Upstream 100 bases:

>100_bases
GGCATGACCTGCACCGTCACCGTCGGCCCGCAGTCGCGCGGCCAGCGGGGGCGCCTGACCACCTGGCTGCAAGACCATCT
ATAAGGCCCCCCGCGCGATC

Downstream 100 bases:

>100_bases
GGAGGGGCGTTCTTTTTTGAAAAAAAGAACCAAAAAACTTTGATTCGTCTGGGGACCATGTGCCGGAGACATACGACGCC
CCAAAACGGATAAAAGTCTT

Product: outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAELKDWWHRFGDAELDRLVDRA
IAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGDSRYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFG
RIRRAVEASEHAVEENVEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQIAQAK
AELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVARPLPQVPEFPATVPSIVLGNRPDIRRAERAYAEATARI
GVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREV
EDAMAAWHDDVEHTELLHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTAMGAG
WQGVGVTASALPVSLEKQNVLARAFQD

Sequences:

>Translated_507_residues
MSMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAELKDWWHRFGDAELDRLVDRA
IAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGDSRYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFG
RIRRAVEASEHAVEENVEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQIAQAK
AELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVARPLPQVPEFPATVPSIVLGNRPDIRRAERAYAEATARI
GVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREV
EDAMAAWHDDVEHTELLHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTAMGAG
WQGVGVTASALPVSLEKQNVLARAFQD
>Mature_506_residues
SMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAELKDWWHRFGDAELDRLVDRAI
AGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGDSRYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFGR
IRRAVEASEHAVEENVEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQIAQAKA
ELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVARPLPQVPEFPATVPSIVLGNRPDIRRAERAYAEATARIG
VAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREVE
DAMAAWHDDVEHTELLHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTAMGAGW
QGVGVTASALPVSLEKQNVLARAFQD

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=467, Percent_Identity=27.1948608137045, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI2367348, Length=482, Percent_Identity=24.0663900414938, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 55889; Mature: 55758

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCH
LKDWWHRFGDAELDRLVDRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGD
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SRYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFGRIRRAVEASEHAVEENVEER
CEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
RAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQIAQAK
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVARPLPQVPEFPATVPSIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHC
GNRPDIRRAERAYAEATARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFML
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
ASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREVEDAMAAWHDDVEHTELLHRA
HHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTAMGAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
WQGVGVTASALPVSLEKQNVLARAFQD
CCCCCCCHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCH
LKDWWHRFGDAELDRLVDRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGD
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SRYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFGRIRRAVEASEHAVEENVEER
CEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
RAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQIAQAK
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVARPLPQVPEFPATVPSIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHC
GNRPDIRRAERAYAEATARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFML
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHH
ASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREVEDAMAAWHDDVEHTELLHRA
HHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTAMGAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
WQGVGVTASALPVSLEKQNVLARAFQD
CCCCCCCHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]