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The map label for this gene is exuT [H]

Identifier: 162147319

GI number: 162147319

Start: 1534445

End: 1535770

Strand: Direct

Name: exuT [H]

Synonym: GDI_1525

Alternate gene names: 162147319

Gene position: 1534445-1535770 (Clockwise)

Preceding gene: 162147315

Following gene: 162147322

Centisome position: 38.9

GC content: 63.05

Gene sequence:

>1326_bases
ATGCTCGCAAGGCAACGCTGGCTGATCTGCAGTCTTCTTTTTGCCGCCACGACCATCAACTATGTGGATCGTCAGGTCCT
GAGCCTGCTGAAGCCGCTTCTGGAGAAAACATTCGACTGGACCGAGAAGGATTACAGTTATCTGGTGATTGCCTTCCAGG
CCTGCTACATGCTCGGGTTCCTGTCTTTCGGCAAACTGGTCGACAGGATCGGGACACGTCTGGGCTATGCGGTCTGCATG
GTGGTGTGGAGCGTGGCCTCGATCGGGCATGCCCTGGTCGGCGGAACGGTCAGCTTCGCGGCGGTACGCGGGCTTCTGGG
ATTTGGTGAATCCGGAAATTTTCCCTCGGCGCTGAAGGCGATTTCGGAATGGTTTCCCGCACGCGAGCGGACCCTGGCGG
TGGGTATCGTGACGGCGGGGACCAGCATCGGGGCGATCATGGCGCCGGCGACGGTGCCCTGGCTGGCGGTGACGTGGGGC
TGGAAGGCGACGTTCATTATCACCGGCCTGTCCGGGTTCGTCTGGCTGGCGGTCTGGCTTTGTCTCTATCGCATTCCCGA
GGAGAAGGCGTCCCTCTCGCCGGAGGAACTGCGTTATATCCGCCAGGATACGAAACCGGACGCAATGCCGGTATTCGCGG
GGCGGTGGATCGACCTGCTCCGGATGAAGGTGACGTGGGCGTTCGCAATCGGAAAGTTCATGACGGACCCGATCTGGTTC
TTCATCCTGTTCTGGCTGCCGTCCTATTTTTCCGACCGGTATCACCTCAACCTGCAGCATCTGGGGCTGCCGCTGATGGC
CGTTTACCTGTCGACCTCGGTGGGCAGCGTCGGGGGGGGATGGCTGTCGTCCTTTCTGGTCCACAAGGGCTGGTCGGTGG
CCCACGCCCGGCGGGCGGTCATGCTGCTGACGGCCCTGCTGGTCGTGCCGCTGGCATTTTCCGCGCAGGTCGGGGCGATG
TGGCTGATGATCGGGCTCCTGAGCCTGGCCGCGGCGGCGCATCAGGGATGGTCGGCGAATATCTATTCCCTGCCGGCGGA
CCATTTCCCCAAGGAGATCATTGCCTCGGTCCAGGGCATCGGCGGCATGGCGGGGTCGATCGGCGGGATGCTGTTCCCGC
TGGGGGTCGGTGTCCTGCTCGATCATTACCGGCACCTGCACAGGATCGAGGAAGGCTATGACATCCTGTTCGTCGTCTGC
GGCGGTGCGTATCTGACGGCCTGGTGCATCATCCAGGTCCTGACCCGTGATCCGCCCAGGGGCCGGGTTCTGCCCGAACC
CGGCAAGGGCCAGTCCCCGCCGTCCCCTTATGTCGGCGCGATCTGA

Upstream 100 bases:

>100_bases
CCCTGGCTGCGCCGTCTGTAATGATGCGATCAAAGCCGGACAAGGTCCTTCTCTTCCTGTCGCTCGTCTCCGAAAAAACA
AGAAAATACCGGAGGACGTC

Downstream 100 bases:

>100_bases
ATCTTGAGCACCTCCGGCCGGTCCCTGATCGTGTCGAAGGTCTGCTGGATATCGGCCAGCGGCACGACGGTGCCGATGAA
GGGCGCCACGCGGAACCGGT

Product: hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLARQRWLICSLLFAATTINYVDRQVLSLLKPLLEKTFDWTEKDYSYLVIAFQACYMLGFLSFGKLVDRIGTRLGYAVCM
VVWSVASIGHALVGGTVSFAAVRGLLGFGESGNFPSALKAISEWFPARERTLAVGIVTAGTSIGAIMAPATVPWLAVTWG
WKATFIITGLSGFVWLAVWLCLYRIPEEKASLSPEELRYIRQDTKPDAMPVFAGRWIDLLRMKVTWAFAIGKFMTDPIWF
FILFWLPSYFSDRYHLNLQHLGLPLMAVYLSTSVGSVGGGWLSSFLVHKGWSVAHARRAVMLLTALLVVPLAFSAQVGAM
WLMIGLLSLAAAAHQGWSANIYSLPADHFPKEIIASVQGIGGMAGSIGGMLFPLGVGVLLDHYRHLHRIEEGYDILFVVC
GGAYLTAWCIIQVLTRDPPRGRVLPEPGKGQSPPSPYVGAI

Sequences:

>Translated_441_residues
MLARQRWLICSLLFAATTINYVDRQVLSLLKPLLEKTFDWTEKDYSYLVIAFQACYMLGFLSFGKLVDRIGTRLGYAVCM
VVWSVASIGHALVGGTVSFAAVRGLLGFGESGNFPSALKAISEWFPARERTLAVGIVTAGTSIGAIMAPATVPWLAVTWG
WKATFIITGLSGFVWLAVWLCLYRIPEEKASLSPEELRYIRQDTKPDAMPVFAGRWIDLLRMKVTWAFAIGKFMTDPIWF
FILFWLPSYFSDRYHLNLQHLGLPLMAVYLSTSVGSVGGGWLSSFLVHKGWSVAHARRAVMLLTALLVVPLAFSAQVGAM
WLMIGLLSLAAAAHQGWSANIYSLPADHFPKEIIASVQGIGGMAGSIGGMLFPLGVGVLLDHYRHLHRIEEGYDILFVVC
GGAYLTAWCIIQVLTRDPPRGRVLPEPGKGQSPPSPYVGAI
>Mature_441_residues
MLARQRWLICSLLFAATTINYVDRQVLSLLKPLLEKTFDWTEKDYSYLVIAFQACYMLGFLSFGKLVDRIGTRLGYAVCM
VVWSVASIGHALVGGTVSFAAVRGLLGFGESGNFPSALKAISEWFPARERTLAVGIVTAGTSIGAIMAPATVPWLAVTWG
WKATFIITGLSGFVWLAVWLCLYRIPEEKASLSPEELRYIRQDTKPDAMPVFAGRWIDLLRMKVTWAFAIGKFMTDPIWF
FILFWLPSYFSDRYHLNLQHLGLPLMAVYLSTSVGSVGGGWLSSFLVHKGWSVAHARRAVMLLTALLVVPLAFSAQVGAM
WLMIGLLSLAAAAHQGWSANIYSLPADHFPKEIIASVQGIGGMAGSIGGMLFPLGVGVLLDHYRHLHRIEEGYDILFVVC
GGAYLTAWCIIQVLTRDPPRGRVLPEPGKGQSPPSPYVGAI

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=295, Percent_Identity=24.0677966101695, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI21322234, Length=294, Percent_Identity=24.4897959183673, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI9945322, Length=294, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI148743791, Length=409, Percent_Identity=22.2493887530562, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI2367193, Length=431, Percent_Identity=29.6983758700696, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082320, Length=390, Percent_Identity=28.2051282051282, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789515, Length=414, Percent_Identity=26.3285024154589, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789152, Length=394, Percent_Identity=26.6497461928934, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI2367379, Length=416, Percent_Identity=25.7211538461538, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI87082231, Length=188, Percent_Identity=26.063829787234, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=425, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=281, Percent_Identity=27.7580071174377, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=418, Percent_Identity=23.9234449760766, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17566884, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=291, Percent_Identity=24.7422680412371, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71991453, Length=291, Percent_Identity=24.7422680412371, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=258, Percent_Identity=25.1937984496124, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648416, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356189, Length=400, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45550460, Length=416, Percent_Identity=25.9615384615385, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584153, Length=360, Percent_Identity=20.8333333333333, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641682, Length=404, Percent_Identity=23.5148514851485, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24655255, Length=375, Percent_Identity=26.4, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583789, Length=368, Percent_Identity=23.0978260869565, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573708, Length=436, Percent_Identity=23.394495412844, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573707, Length=436, Percent_Identity=23.394495412844, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920686, Length=442, Percent_Identity=22.1719457013575, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639764, Length=438, Percent_Identity=21.2328767123288, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20129235, Length=394, Percent_Identity=25.1269035532995, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221474708, Length=407, Percent_Identity=22.1130221130221, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48465; Mature: 48465

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARQRWLICSLLFAATTINYVDRQVLSLLKPLLEKTFDWTEKDYSYLVIAFQACYMLGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LSFGKLVDRIGTRLGYAVCMVVWSVASIGHALVGGTVSFAAVRGLLGFGESGNFPSALKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHH
ISEWFPARERTLAVGIVTAGTSIGAIMAPATVPWLAVTWGWKATFIITGLSGFVWLAVWL
HHHHCCCCCCEEEEEEEECCCCCCHHHCCCCCCEEEEEECCEEEEEEECHHHHHHHHHHH
CLYRIPEEKASLSPEELRYIRQDTKPDAMPVFAGRWIDLLRMKVTWAFAIGKFMTDPIWF
HHHHCCHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILFWLPSYFSDRYHLNLQHLGLPLMAVYLSTSVGSVGGGWLSSFLVHKGWSVAHARRAV
HHHHHHHHHCCCCEEEEHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHH
MLLTALLVVPLAFSAQVGAMWLMIGLLSLAAAAHQGWSANIYSLPADHFPKEIIASVQGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHCCCHHHHHHHHCC
GGMAGSIGGMLFPLGVGVLLDHYRHLHRIEEGYDILFVVCGGAYLTAWCIIQVLTRDPPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCC
GRVLPEPGKGQSPPSPYVGAI
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLARQRWLICSLLFAATTINYVDRQVLSLLKPLLEKTFDWTEKDYSYLVIAFQACYMLGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LSFGKLVDRIGTRLGYAVCMVVWSVASIGHALVGGTVSFAAVRGLLGFGESGNFPSALKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHH
ISEWFPARERTLAVGIVTAGTSIGAIMAPATVPWLAVTWGWKATFIITGLSGFVWLAVWL
HHHHCCCCCCEEEEEEEECCCCCCHHHCCCCCCEEEEEECCEEEEEEECHHHHHHHHHHH
CLYRIPEEKASLSPEELRYIRQDTKPDAMPVFAGRWIDLLRMKVTWAFAIGKFMTDPIWF
HHHHCCHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILFWLPSYFSDRYHLNLQHLGLPLMAVYLSTSVGSVGGGWLSSFLVHKGWSVAHARRAV
HHHHHHHHHCCCCEEEEHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHH
MLLTALLVVPLAFSAQVGAMWLMIGLLSLAAAAHQGWSANIYSLPADHFPKEIIASVQGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHCCCHHHHHHHHCC
GGMAGSIGGMLFPLGVGVLLDHYRHLHRIEEGYDILFVVCGGAYLTAWCIIQVLTRDPPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCC
GRVLPEPGKGQSPPSPYVGAI
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]