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The map label for this gene is mcpA [H]

Identifier: 162147293

GI number: 162147293

Start: 1505754

End: 1507508

Strand: Reverse

Name: mcpA [H]

Synonym: GDI_1498

Alternate gene names: 162147293

Gene position: 1507508-1505754 (Counterclockwise)

Preceding gene: 162147299

Following gene: 162147292

Centisome position: 38.22

GC content: 66.55

Gene sequence:

>1755_bases
TTGTCCAGGAAAGTGAAGAAAATGTTCGGATTTCGGCACCGCGACCGGACGGACGCACGGGCGACGCTGGCGGCGCTCGA
CCGTTCCCTCGCGATCATCGAGTTCGACCCCACGGGAAAGATCCTGACGGCCAACGCGAATTTCTGCACGGCAATGGGCT
ACCGGCTGGACGAGATCCAGGGCCGGTCCCACAGCATGTTCGTCGATCCCGACGAGGCCCGAAGCCCCGAATACACGGCA
TTCTGGGCCAGGCTGGCCCGTGGCGAGTTCGAGGCACGGGACTATATGCGTATCGGCAAGGGCGGCGAGGAGATCTGGGT
TCAGGCGTCCTACAACCCGGTGCGCAACTGGCGCGGCGCGGTGACCAGGATCGTGAAGGTGGCGACGGTCATCACCGACG
AAACGCTTCGGAATGCCGATTTCGCGGGCAAGATCGAAGCGATTTCCCGCTCCCAGGCCGTGATCGAATTCACGCCGGAC
GGGCACGTCCTGACCGCCAACGACAATTTCCTCAACGCCCTGGACTACCGGCTGGACGAAATCCAGGGCCGTCATCACCG
CATGTTGGTCGAGCCGGAATTCGCACGTTCCGGTGCCTATGACGCATTCTGGAAAAAGCTGCGGAACGGCGAATTCGTCG
CCGCCGAATTCAGGCGGATCGGCAAGCATGGCAAGGTGGTCTGGATCCAGGCCTCGTACAATCCGATTTTCGACCGGAAG
GGACGGGTCATCAAGGTCGTGAAGTTCGCGACCGACGTCACCAGCCGCGTGAACGCCGTGGACGGGATCGTCGGCGCGCT
GGAGGAACTGGCCTGCAACAACCTCGCCTACCGGCTCGAAGGCCCGATCGATTCCGCTTACGAGAAGGTGCGGGACGATT
TCAACGCGGCCCTGGACATGCTGGAAGAGACGATGGTGGCCATTGCCGCCTCGGCCGGCGGCGTGGGCAACGGCGCGCAC
GAAATCGCCTCGGCCTCGGGCGACCTGTCGCGCCGGACTGAAACGCAGGCCGCCAGCCTGGAAGAAACCGCCGCCGCCCT
GAACGAGATCACGGCCACGGTGACCCGTAGCGCCCAGGGCGCGCAAGAGGCGTCAACGGCCGCCTCGGCGGCGCGCGGCG
ATGCCGGGAAGTCCGGCAAGGTCGTGCGGGAAACGGTTTCCGCCATGGGCGAAATCCGGGATTCGTCGCGCGAGATCACG
CAGATCGTCAGCGTGATCGACCAGATCGCCTTCCAGACCAACCTGCTGGCGCTCAATGCCGGGGTCGAGGCCGCACGTGC
CGGGGACGCCGGCCGCGGTTTCGCCGTGGTGGCGTCCGAGGTCCGCGCCCTGGCCCAGCAATCGGCGCAGGCGGCGCGCG
AGATCAGGGCCCTGATCGACAGGTCCGGCGCCCATGTCGAGCGCGGCGTGAAACTGGTGGGCGAAACCGGGGACGCCCTG
GCCGCGATCGTGGCCAGGGTGGCCCAGATCGACACGCTGGTATCGGACATCGCGGCGTCGTCCCAGCAGCAGGCCATGGG
GCTGGCCCAGGTCAATGTCGCGGTCACCCAACTGGACCAGATGACCCAGCAGAACGCCGCCATGGTCGAGGAAACGACCG
CCGCCACGGCCAGCCTGAACCAGGAATCCCGGGAACTGACGCGGCTGATCGGCCGGTTCCAGACCCGGGGTGGAGAACCG
CGCCCGCGGGCCCTGCCGCAATCCGCCCGGCCGCAGGCGCCCACACAGGTCGCCTATCGGCGGCTGTCCGCGTAA

Upstream 100 bases:

>100_bases
GGAATCGAGTCGCGGGAAATAGGGTTTCAGCCTTGCTGCATTGACATAAATTAAAAACATTATTAATAAAAAATTCATAT
ACCTCAATCGACAAAAAATT

Downstream 100 bases:

>100_bases
ACTCTCACGGATGATCAGCCTTTTCGACCTTTTCAGGATCGGCATCGGCCCGTCCTCGTCCCACACGGTCGGGCCGATGC
GCGCGGCCCGGCGCTTCGCC

Product: chemoreceptor mcpA

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSRKVKKMFGFRHRDRTDARATLAALDRSLAIIEFDPTGKILTANANFCTAMGYRLDEIQGRSHSMFVDPDEARSPEYTA
FWARLARGEFEARDYMRIGKGGEEIWVQASYNPVRNWRGAVTRIVKVATVITDETLRNADFAGKIEAISRSQAVIEFTPD
GHVLTANDNFLNALDYRLDEIQGRHHRMLVEPEFARSGAYDAFWKKLRNGEFVAAEFRRIGKHGKVVWIQASYNPIFDRK
GRVIKVVKFATDVTSRVNAVDGIVGALEELACNNLAYRLEGPIDSAYEKVRDDFNAALDMLEETMVAIAASAGGVGNGAH
EIASASGDLSRRTETQAASLEETAAALNEITATVTRSAQGAQEASTAASAARGDAGKSGKVVRETVSAMGEIRDSSREIT
QIVSVIDQIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQQSAQAAREIRALIDRSGAHVERGVKLVGETGDAL
AAIVARVAQIDTLVSDIAASSQQQAMGLAQVNVAVTQLDQMTQQNAAMVEETTAATASLNQESRELTRLIGRFQTRGGEP
RPRALPQSARPQAPTQVAYRRLSA

Sequences:

>Translated_584_residues
MSRKVKKMFGFRHRDRTDARATLAALDRSLAIIEFDPTGKILTANANFCTAMGYRLDEIQGRSHSMFVDPDEARSPEYTA
FWARLARGEFEARDYMRIGKGGEEIWVQASYNPVRNWRGAVTRIVKVATVITDETLRNADFAGKIEAISRSQAVIEFTPD
GHVLTANDNFLNALDYRLDEIQGRHHRMLVEPEFARSGAYDAFWKKLRNGEFVAAEFRRIGKHGKVVWIQASYNPIFDRK
GRVIKVVKFATDVTSRVNAVDGIVGALEELACNNLAYRLEGPIDSAYEKVRDDFNAALDMLEETMVAIAASAGGVGNGAH
EIASASGDLSRRTETQAASLEETAAALNEITATVTRSAQGAQEASTAASAARGDAGKSGKVVRETVSAMGEIRDSSREIT
QIVSVIDQIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQQSAQAAREIRALIDRSGAHVERGVKLVGETGDAL
AAIVARVAQIDTLVSDIAASSQQQAMGLAQVNVAVTQLDQMTQQNAAMVEETTAATASLNQESRELTRLIGRFQTRGGEP
RPRALPQSARPQAPTQVAYRRLSA
>Mature_583_residues
SRKVKKMFGFRHRDRTDARATLAALDRSLAIIEFDPTGKILTANANFCTAMGYRLDEIQGRSHSMFVDPDEARSPEYTAF
WARLARGEFEARDYMRIGKGGEEIWVQASYNPVRNWRGAVTRIVKVATVITDETLRNADFAGKIEAISRSQAVIEFTPDG
HVLTANDNFLNALDYRLDEIQGRHHRMLVEPEFARSGAYDAFWKKLRNGEFVAAEFRRIGKHGKVVWIQASYNPIFDRKG
RVIKVVKFATDVTSRVNAVDGIVGALEELACNNLAYRLEGPIDSAYEKVRDDFNAALDMLEETMVAIAASAGGVGNGAHE
IASASGDLSRRTETQAASLEETAAALNEITATVTRSAQGAQEASTAASAARGDAGKSGKVVRETVSAMGEIRDSSREITQ
IVSVIDQIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQQSAQAAREIRALIDRSGAHVERGVKLVGETGDALA
AIVARVAQIDTLVSDIAASSQQQAMGLAQVNVAVTQLDQMTQQNAAMVEETTAATASLNQESRELTRLIGRFQTRGGEPR
PRALPQSARPQAPTQVAYRRLSA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=316, Percent_Identity=43.3544303797468, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=49.063670411985, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1787690, Length=255, Percent_Identity=46.2745098039216, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1788194, Length=236, Percent_Identity=48.728813559322, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=38.0753138075314, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63300; Mature: 63169

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKVKKMFGFRHRDRTDARATLAALDRSLAIIEFDPTGKILTANANFCTAMGYRLDEIQ
CCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHHHCCHHHHHC
GRSHSMFVDPDEARSPEYTAFWARLARGEFEARDYMRIGKGGEEIWVQASYNPVRNWRGA
CCCCCEEECCHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
VTRIVKVATVITDETLRNADFAGKIEAISRSQAVIEFTPDGHVLTANDNFLNALDYRLDE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHH
IQGRHHRMLVEPEFARSGAYDAFWKKLRNGEFVAAEFRRIGKHGKVVWIQASYNPIFDRK
HCCCCCEEEECCHHHHCCCHHHHHHHHCCCCEEHHHHHHHCCCCCEEEEEECCCCCCCCC
GRVIKVVKFATDVTSRVNAVDGIVGALEELACNNLAYRLEGPIDSAYEKVRDDFNAALDM
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
LEETMVAIAASAGGVGNGAHEIASASGDLSRRTETQAASLEETAAALNEITATVTRSAQG
HHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQEASTAASAARGDAGKSGKVVRETVSAMGEIRDSSREITQIVSVIDQIAFQTNLLALNA
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
GVEAARAGDAGRGFAVVASEVRALAQQSAQAAREIRALIDRSGAHVERGVKLVGETGDAL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHEECCCCHHH
AAIVARVAQIDTLVSDIAASSQQQAMGLAQVNVAVTQLDQMTQQNAAMVEETTAATASLN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QESRELTRLIGRFQTRGGEPRPRALPQSARPQAPTQVAYRRLSA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SRKVKKMFGFRHRDRTDARATLAALDRSLAIIEFDPTGKILTANANFCTAMGYRLDEIQ
CCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCHHHHCCHHHHHC
GRSHSMFVDPDEARSPEYTAFWARLARGEFEARDYMRIGKGGEEIWVQASYNPVRNWRGA
CCCCCEEECCHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
VTRIVKVATVITDETLRNADFAGKIEAISRSQAVIEFTPDGHVLTANDNFLNALDYRLDE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHH
IQGRHHRMLVEPEFARSGAYDAFWKKLRNGEFVAAEFRRIGKHGKVVWIQASYNPIFDRK
HCCCCCEEEECCHHHHCCCHHHHHHHHCCCCEEHHHHHHHCCCCCEEEEEECCCCCCCCC
GRVIKVVKFATDVTSRVNAVDGIVGALEELACNNLAYRLEGPIDSAYEKVRDDFNAALDM
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
LEETMVAIAASAGGVGNGAHEIASASGDLSRRTETQAASLEETAAALNEITATVTRSAQG
HHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQEASTAASAARGDAGKSGKVVRETVSAMGEIRDSSREITQIVSVIDQIAFQTNLLALNA
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
GVEAARAGDAGRGFAVVASEVRALAQQSAQAAREIRALIDRSGAHVERGVKLVGETGDAL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHEECCCCHHH
AAIVARVAQIDTLVSDIAASSQQQAMGLAQVNVAVTQLDQMTQQNAAMVEETTAATASLN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QESRELTRLIGRFQTRGGEPRPRALPQSARPQAPTQVAYRRLSA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]