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The map label for this gene is sdaA [H]

Identifier: 162147292

GI number: 162147292

Start: 1504385

End: 1505743

Strand: Reverse

Name: sdaA [H]

Synonym: GDI_1497

Alternate gene names: 162147292

Gene position: 1505743-1504385 (Counterclockwise)

Preceding gene: 162147293

Following gene: 162147290

Centisome position: 38.18

GC content: 71.38

Gene sequence:

>1359_bases
ATGATCAGCCTTTTCGACCTTTTCAGGATCGGCATCGGCCCGTCCTCGTCCCACACGGTCGGGCCGATGCGCGCGGCCCG
GCGCTTCGCCACGCACCTGCCCCCCGCGATGCCCGTCGCGCGGCTGCGCGTCACGCTCTATGGCTCGCTGGCCTGGACCG
CCAGCGGTCACGCCACCGACAAGGCCGTCATCCTGGGCCTGGCGGGCGAGACGCCCGAGGGCATTGACCCCGACGCCGCC
GGAGACATCGTCCGCCGGATCGGCGCCGCGCGCACGGTCCTGCTGCATGGGCGCGCCGTCGCCTTCGATCCCGCCCGCGA
CATCGTGCTGGACCGCGACACGATCCCGCCCGTCCACCCCAACACGCTGCAGTTCCAGGCCCTGGCCGCCGACGGCACGC
CGCTGGAAACCGGGCGATTCTGTTCGGTCGGCGGCGGCTTCATCGTGCCGGAAGACGCCACGAAGCATGCGGGCTATGCC
CAGCCGGCCATGCCGCTGGACTTCGCCAGCGGCGTGGAACTGCTGGACCGCACGCGCCAGAGCGGCCTGGGCATCGCGGG
CGTCGTCCTGGCCAACGAGACCGCGCTGCGCCCGCCCGCCGAAATCACGGCGTACCTGGACCGGATCATCGACACCATGA
TGACCTGCGTCGAACGCGGTCTGGTCCAGCGCGGCACGCTGCCCGGGCGGATCAAGGTCCCGCGCCGCGCGGCGGCGCTG
CACGAACGGCTGCTGGAGCGCACGCGCCTCAACCAGCGGCCACCGCACGAGGCGATGGACTGGATCAGCCTGTTCGCCAT
CGCGGTGAACGAGGAAAACGCTGCCGGCGGCCGCGTCGTGACCGCGCCCACCAACGGCGCGGCCGGGGTCATCCCCGCCG
TGCTGCGCTATTACCGCGATTTCTGCCCCGGGGCCTCACGCGCCGGGATGCACGATTTCCTGCTGACGGCGGCGGCGGTC
GGCGGCCTGTTCAAGCTCAACGCCTCGATCTCGGGGGCCGAGGTCGGGTGCCAGGGCGAGGTCGGGGTGGCGTCCTCGAT
GGCGGCGGCGGGCCTGGCGGCGGCACTGGGCGCGACCCCGCTGCAGATCGAGAACGCCGCCGAGATCGGCATGGAACACC
ATCTGGGCATGACGTGCGACCCGGTCGCCGGCCTGGTTCAGATCCCGTGCATCGAGCGCAACGCCTTCGGCGCGGTGAAG
GCGGTCAATGCCGCCTCGCTGGCCATGCATGGCGACGGGGCGCACCAGGTCTCGCTGGACCAGGTGATCCGCACCATGGC
GGAAACGGGGCGGGACATGAACCATCGCTACAAGGAAACCGCGCTGGGCGGCCTGGCGGTCAATTTCCCGGAATGCTGA

Upstream 100 bases:

>100_bases
CGGGGTGGAGAACCGCGCCCGCGGGCCCTGCCGCAATCCGCCCGGCCGCAGGCGCCCACACAGGTCGCCTATCGGCGGCT
GTCCGCGTAAACTCTCACGG

Downstream 100 bases:

>100_bases
CCGCGCGGATAGGTCGCGGCCCGCTTCACGACCCCTTCACGACATGGTGATATAGGTCAGCAGGATCGATGCGATCGCGA
CGAAGGCGACGGACGCGCTG

Product: L-serine deaminase /L-threonine deaminase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MISLFDLFRIGIGPSSSHTVGPMRAARRFATHLPPAMPVARLRVTLYGSLAWTASGHATDKAVILGLAGETPEGIDPDAA
GDIVRRIGAARTVLLHGRAVAFDPARDIVLDRDTIPPVHPNTLQFQALAADGTPLETGRFCSVGGGFIVPEDATKHAGYA
QPAMPLDFASGVELLDRTRQSGLGIAGVVLANETALRPPAEITAYLDRIIDTMMTCVERGLVQRGTLPGRIKVPRRAAAL
HERLLERTRLNQRPPHEAMDWISLFAIAVNEENAAGGRVVTAPTNGAAGVIPAVLRYYRDFCPGASRAGMHDFLLTAAAV
GGLFKLNASISGAEVGCQGEVGVASSMAAAGLAAALGATPLQIENAAEIGMEHHLGMTCDPVAGLVQIPCIERNAFGAVK
AVNAASLAMHGDGAHQVSLDQVIRTMAETGRDMNHRYKETALGGLAVNFPEC

Sequences:

>Translated_452_residues
MISLFDLFRIGIGPSSSHTVGPMRAARRFATHLPPAMPVARLRVTLYGSLAWTASGHATDKAVILGLAGETPEGIDPDAA
GDIVRRIGAARTVLLHGRAVAFDPARDIVLDRDTIPPVHPNTLQFQALAADGTPLETGRFCSVGGGFIVPEDATKHAGYA
QPAMPLDFASGVELLDRTRQSGLGIAGVVLANETALRPPAEITAYLDRIIDTMMTCVERGLVQRGTLPGRIKVPRRAAAL
HERLLERTRLNQRPPHEAMDWISLFAIAVNEENAAGGRVVTAPTNGAAGVIPAVLRYYRDFCPGASRAGMHDFLLTAAAV
GGLFKLNASISGAEVGCQGEVGVASSMAAAGLAAALGATPLQIENAAEIGMEHHLGMTCDPVAGLVQIPCIERNAFGAVK
AVNAASLAMHGDGAHQVSLDQVIRTMAETGRDMNHRYKETALGGLAVNFPEC
>Mature_452_residues
MISLFDLFRIGIGPSSSHTVGPMRAARRFATHLPPAMPVARLRVTLYGSLAWTASGHATDKAVILGLAGETPEGIDPDAA
GDIVRRIGAARTVLLHGRAVAFDPARDIVLDRDTIPPVHPNTLQFQALAADGTPLETGRFCSVGGGFIVPEDATKHAGYA
QPAMPLDFASGVELLDRTRQSGLGIAGVVLANETALRPPAEITAYLDRIIDTMMTCVERGLVQRGTLPGRIKVPRRAAAL
HERLLERTRLNQRPPHEAMDWISLFAIAVNEENAAGGRVVTAPTNGAAGVIPAVLRYYRDFCPGASRAGMHDFLLTAAAV
GGLFKLNASISGAEVGCQGEVGVASSMAAAGLAAALGATPLQIENAAEIGMEHHLGMTCDPVAGLVQIPCIERNAFGAVK
AVNAASLAMHGDGAHQVSLDQVIRTMAETGRDMNHRYKETALGGLAVNFPEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=452, Percent_Identity=48.8938053097345, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789161, Length=457, Percent_Identity=48.5776805251641, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI48994925, Length=455, Percent_Identity=50.7692307692308, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 47466; Mature: 47466

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLFDLFRIGIGPSSSHTVGPMRAARRFATHLPPAMPVARLRVTLYGSLAWTASGHATD
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEEEEEEEEECCCCCCC
KAVILGLAGETPEGIDPDAAGDIVRRIGAARTVLLHGRAVAFDPARDIVLDRDTIPPVHP
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCEEEECCCCCEEEECCCCCCCCC
NTLQFQALAADGTPLETGRFCSVGGGFIVPEDATKHAGYAQPAMPLDFASGVELLDRTRQ
CCEEEEEEECCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SGLGIAGVVLANETALRPPAEITAYLDRIIDTMMTCVERGLVQRGTLPGRIKVPRRAAAL
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHH
HERLLERTRLNQRPPHEAMDWISLFAIAVNEENAAGGRVVTAPTNGAAGVIPAVLRYYRD
HHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
FCPGASRAGMHDFLLTAAAVGGLFKLNASISGAEVGCQGEVGVASSMAAAGLAAALGATP
HCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LQIENAAEIGMEHHLGMTCDPVAGLVQIPCIERNAFGAVKAVNAASLAMHGDGAHQVSLD
EEECCHHHHCHHHCCCCCCCHHCCCEECCCCCCCCCCHHHHCCHHHEEEECCCCCEECHH
QVIRTMAETGRDMNHRYKETALGGLAVNFPEC
HHHHHHHHCCCHHHHHHHHHHHCCEEECCCCC
>Mature Secondary Structure
MISLFDLFRIGIGPSSSHTVGPMRAARRFATHLPPAMPVARLRVTLYGSLAWTASGHATD
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEEEEEEEEECCCCCCC
KAVILGLAGETPEGIDPDAAGDIVRRIGAARTVLLHGRAVAFDPARDIVLDRDTIPPVHP
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCEEEECCCCCEEEECCCCCCCCC
NTLQFQALAADGTPLETGRFCSVGGGFIVPEDATKHAGYAQPAMPLDFASGVELLDRTRQ
CCEEEEEEECCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SGLGIAGVVLANETALRPPAEITAYLDRIIDTMMTCVERGLVQRGTLPGRIKVPRRAAAL
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHH
HERLLERTRLNQRPPHEAMDWISLFAIAVNEENAAGGRVVTAPTNGAAGVIPAVLRYYRD
HHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
FCPGASRAGMHDFLLTAAAVGGLFKLNASISGAEVGCQGEVGVASSMAAAGLAAALGATP
HCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LQIENAAEIGMEHHLGMTCDPVAGLVQIPCIERNAFGAVKAVNAASLAMHGDGAHQVSLD
EEECCHHHHCHHHCCCCCCCHHCCCEECCCCCCCCCCHHHHCCHHHEEEECCCCCEECHH
QVIRTMAETGRDMNHRYKETALGGLAVNFPEC
HHHHHHHHCCCHHHHHHHHHHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]