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The map label for this gene is yggV [C]

Identifier: 162147172

GI number: 162147172

Start: 1381304

End: 1381921

Strand: Reverse

Name: yggV [C]

Synonym: GDI_1377

Alternate gene names: 162147172

Gene position: 1381921-1381304 (Counterclockwise)

Preceding gene: 162147173

Following gene: 162147171

Centisome position: 35.04

GC content: 72.33

Gene sequence:

>618_bases
GTGAGCGGGCAGGCGACACGCCGCCTGGCGCGCGGCGACCGGCTGGTCCTGGCCAGCCACAATGCGGGAAAGCTGGTGGA
ATTTTCCGCCCTGCTGGACGGATACGGCATCACCGTCCTCTCGGCCGGCCAGCTCGGCCTGCCCGAACCCGAGGAAACCG
CCGAGACCTTCGTCGGCAATGCGGCCCTGAAGGCCCATGCCGCGGCGCAGGCCAGCGGCCTGCCGGCGCTGGCGGATGAT
TCCGGCCTGTGCGTCGCGGCCCTGGGCGGCGCGCCCGGGATCTATTCCGCCCGCTGGGCCGGACCGGAGAAGGATTTTCC
GGGCGCCATGGCCCGTATCCACGAGGGCATCGGCGACGATCCCGACCGGTCGGCCTGGTTCGTCTCGGTGCTGTGCCTGG
CCTGGCCCGACGGCACGATCCGCAGCTTCGAGGGCCGGATCGACGGCCGGATCACCTGGCCGCCGCGGGGCACCCACGGC
CACGGCTACGACCCGGTCTTCACCCCCGAGGGCCGCGACCGGACCTTCGCCGAAATGCCCGAGGCCGAGAAAAACACCAT
CAGCCACCGCGCCCGGGCCTTCGCCCTGTTCCGTGACGCCTGCCTGCCCGGGGACTGA

Upstream 100 bases:

>100_bases
AGTTCGACACGCTGCTGCGTCTGGCGCGAACCGGCACCGCGCAGCTTTTCATCGCCCAGCGCCAGGCCGTGGACGCCGCC
CTGACCGCGCGGACCGCACC

Downstream 100 bases:

>100_bases
ATACGCATCCACCGTACCCCCGGCGGGATCGTCCCGCCGGCACGCGCGACCGCACCCGGTTCGATACGGCACGCCGAGCC
TCATTGAAGGACATCCGATG

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSGQATRRLARGDRLVLASHNAGKLVEFSALLDGYGITVLSAGQLGLPEPEETAETFVGNAALKAHAAAQASGLPALADD
SGLCVAALGGAPGIYSARWAGPEKDFPGAMARIHEGIGDDPDRSAWFVSVLCLAWPDGTIRSFEGRIDGRITWPPRGTHG
HGYDPVFTPEGRDRTFAEMPEAEKNTISHRARAFALFRDACLPGD

Sequences:

>Translated_205_residues
MSGQATRRLARGDRLVLASHNAGKLVEFSALLDGYGITVLSAGQLGLPEPEETAETFVGNAALKAHAAAQASGLPALADD
SGLCVAALGGAPGIYSARWAGPEKDFPGAMARIHEGIGDDPDRSAWFVSVLCLAWPDGTIRSFEGRIDGRITWPPRGTHG
HGYDPVFTPEGRDRTFAEMPEAEKNTISHRARAFALFRDACLPGD
>Mature_204_residues
SGQATRRLARGDRLVLASHNAGKLVEFSALLDGYGITVLSAGQLGLPEPEETAETFVGNAALKAHAAAQASGLPALADDS
GLCVAALGGAPGIYSARWAGPEKDFPGAMARIHEGIGDDPDRSAWFVSVLCLAWPDGTIRSFEGRIDGRITWPPRGTHGH
GYDPVFTPEGRDRTFAEMPEAEKNTISHRARAFALFRDACLPGD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=186, Percent_Identity=37.6344086021505, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI31657144, Length=160, Percent_Identity=38.75, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=43.0769230769231, Blast_Score=140, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17556833, Length=190, Percent_Identity=31.0526315789474, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322529, Length=202, Percent_Identity=30.1980198019802, Blast_Score=78, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=35.6382978723404, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21695; Mature: 21564

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQATRRLARGDRLVLASHNAGKLVEFSALLDGYGITVLSAGQLGLPEPEETAETFVGN
CCCHHHHHHHCCCEEEEEECCCCCEEEHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCC
AALKAHAAAQASGLPALADDSGLCVAALGGAPGIYSARWAGPEKDFPGAMARIHEGIGDD
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
PDRSAWFVSVLCLAWPDGTIRSFEGRIDGRITWPPRGTHGHGYDPVFTPEGRDRTFAEMP
CCCHHHHHHHHHHHCCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHCC
EAEKNTISHRARAFALFRDACLPGD
CHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGQATRRLARGDRLVLASHNAGKLVEFSALLDGYGITVLSAGQLGLPEPEETAETFVGN
CCHHHHHHHCCCEEEEEECCCCCEEEHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCC
AALKAHAAAQASGLPALADDSGLCVAALGGAPGIYSARWAGPEKDFPGAMARIHEGIGDD
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
PDRSAWFVSVLCLAWPDGTIRSFEGRIDGRITWPPRGTHGHGYDPVFTPEGRDRTFAEMP
CCCHHHHHHHHHHHCCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHCC
EAEKNTISHRARAFALFRDACLPGD
CHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA