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The map label for this gene is ltrA [H]

Identifier: 162147153

GI number: 162147153

Start: 1359951

End: 1360838

Strand: Direct

Name: ltrA [H]

Synonym: GDI_1358

Alternate gene names: 162147153

Gene position: 1359951-1360838 (Clockwise)

Preceding gene: 162147152

Following gene: 162147154

Centisome position: 34.48

GC content: 67.12

Gene sequence:

>888_bases
ATGGATCTGCTTTCTGCCCTTCATAGCTTCGTTCGCGTCGCGGCGACGGGGTCGTTTTCCGCTGTTTCGCGCGAAACCGG
TGCCAGCCAGCCGACGATTTCGCGGCACATCGCGCTGCTGGAGGCGCATTACGGCGCGACCCTGTTCGCGCGTACCACCC
GCAGCCTGATGATGACCGAGGATGGGCGCAGCCTGCTGCCCCACGCTTACGAAGTGCTGGAAATTCTGGAAACCGCCGAA
ACCGCCCTCGGCCGCCGCCGGGCCTCGGTGTCCGGCCTGGTGCGGCTGGGCGTGACCACCGCGTTCGGCCTCTATACCAC
CGGCCGGCTGGGGGAATTGCTGGAACAGCACCCCGATCTTTCGGTCGAACTGATCATGCGCGACGGCTTCGGCGACCTGG
TCGAGGAAGGGCTGGACCTGGCGGTGCGTGTCGGTGAAATCGCCGAGGGCTCGCTGATCGCGCGGCGGCTGGGCACGGTC
AAGCGCATCGCCGTGGCCACGCCGGCCTATCTGGACCGGCGCGGCACGCCGCAGCATCCGCGCGACCTGCTGAACCATCC
CTGCATTGCCTATACCTATGGCGGCACGCGTCATGACTGGCATTTCGAAGGCAATGGCGAGGAAAGCGTCGTCGCCGCCA
GCGGCCCCTTCCGCGCCAACAGCAGCGAGGCCGTGCTGCAGGCCACGCTGGCCGGCATGGGCATCGGGCTGCTGCCGTCC
TTCCAGGTGGACGAAGACGTCGCATCCGGCCGGCTGGTGCGGCTGTTTCCCGACTGGACGGTGCCGGAGCTGCCCTTCTA
CGCCGTGCATACCGGGCCGCGTACCCTGCCGTTGCGGACGCGGACGGTGCTGGATTTCCTGATCGATATTTCGGATGTGC
TGCGGTAG

Upstream 100 bases:

>100_bases
TGATGCGTCAGGCACATGACGGCGCTGTTTTATGCTAGATTGTGCATAAATAGTCCGAGGCATAGAAAGGTGTTCGAACA
AATTCCGAGCATCGGTGGCC

Downstream 100 bases:

>100_bases
TTCTTTTTCTGAAGAAAAAGAAGACCTTACTCCACCGGCAACACCGACGCCGGGTCCCGGCTGGCCCGCACCAGATCCGG
CGACCCCGCCACCAGTTCGC

Product: transcriptional regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDLLSALHSFVRVAATGSFSAVSRETGASQPTISRHIALLEAHYGATLFARTTRSLMMTEDGRSLLPHAYEVLEILETAE
TALGRRRASVSGLVRLGVTTAFGLYTTGRLGELLEQHPDLSVELIMRDGFGDLVEEGLDLAVRVGEIAEGSLIARRLGTV
KRIAVATPAYLDRRGTPQHPRDLLNHPCIAYTYGGTRHDWHFEGNGEESVVAASGPFRANSSEAVLQATLAGMGIGLLPS
FQVDEDVASGRLVRLFPDWTVPELPFYAVHTGPRTLPLRTRTVLDFLIDISDVLR

Sequences:

>Translated_295_residues
MDLLSALHSFVRVAATGSFSAVSRETGASQPTISRHIALLEAHYGATLFARTTRSLMMTEDGRSLLPHAYEVLEILETAE
TALGRRRASVSGLVRLGVTTAFGLYTTGRLGELLEQHPDLSVELIMRDGFGDLVEEGLDLAVRVGEIAEGSLIARRLGTV
KRIAVATPAYLDRRGTPQHPRDLLNHPCIAYTYGGTRHDWHFEGNGEESVVAASGPFRANSSEAVLQATLAGMGIGLLPS
FQVDEDVASGRLVRLFPDWTVPELPFYAVHTGPRTLPLRTRTVLDFLIDISDVLR
>Mature_295_residues
MDLLSALHSFVRVAATGSFSAVSRETGASQPTISRHIALLEAHYGATLFARTTRSLMMTEDGRSLLPHAYEVLEILETAE
TALGRRRASVSGLVRLGVTTAFGLYTTGRLGELLEQHPDLSVELIMRDGFGDLVEEGLDLAVRVGEIAEGSLIARRLGTV
KRIAVATPAYLDRRGTPQHPRDLLNHPCIAYTYGGTRHDWHFEGNGEESVVAASGPFRANSSEAVLQATLAGMGIGLLPS
FQVDEDVASGRLVRLFPDWTVPELPFYAVHTGPRTLPLRTRTVLDFLIDISDVLR

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=281, Percent_Identity=31.3167259786477, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=31.3588850174216, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=31.0580204778157, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=32.0689655172414, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=29.6928327645051, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=29.9651567944251, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787589, Length=271, Percent_Identity=28.4132841328413, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=27.5092936802974, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790011, Length=286, Percent_Identity=23.7762237762238, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082132, Length=279, Percent_Identity=24.0143369175627, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786713, Length=268, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=154, Percent_Identity=26.6233766233766, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=280, Percent_Identity=23.2142857142857, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=28.2758620689655, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32100; Mature: 32100

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLSALHSFVRVAATGSFSAVSRETGASQPTISRHIALLEAHYGATLFARTTRSLMMTE
CHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEC
DGRSLLPHAYEVLEILETAETALGRRRASVSGLVRLGVTTAFGLYTTGRLGELLEQHPDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
SVELIMRDGFGDLVEEGLDLAVRVGEIAEGSLIARRLGTVKRIAVATPAYLDRRGTPQHP
EEEEEEECCCHHHHHHCHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
RDLLNHPCIAYTYGGTRHDWHFEGNGEESVVAASGPFRANSSEAVLQATLAGMGIGLLPS
HHHHCCCEEEEECCCCCCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCC
FQVDEDVASGRLVRLFPDWTVPELPFYAVHTGPRTLPLRTRTVLDFLIDISDVLR
CCCCCHHHCCCEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLLSALHSFVRVAATGSFSAVSRETGASQPTISRHIALLEAHYGATLFARTTRSLMMTE
CHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEC
DGRSLLPHAYEVLEILETAETALGRRRASVSGLVRLGVTTAFGLYTTGRLGELLEQHPDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
SVELIMRDGFGDLVEEGLDLAVRVGEIAEGSLIARRLGTVKRIAVATPAYLDRRGTPQHP
EEEEEEECCCHHHHHHCHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
RDLLNHPCIAYTYGGTRHDWHFEGNGEESVVAASGPFRANSSEAVLQATLAGMGIGLLPS
HHHHCCCEEEEECCCCCCCEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCC
FQVDEDVASGRLVRLFPDWTVPELPFYAVHTGPRTLPLRTRTVLDFLIDISDVLR
CCCCCHHHCCCEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]