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The map label for this gene is moeB [H]

Identifier: 162147088

GI number: 162147088

Start: 1292883

End: 1293689

Strand: Reverse

Name: moeB [H]

Synonym: GDI_1293

Alternate gene names: 162147088

Gene position: 1293689-1292883 (Counterclockwise)

Preceding gene: 162147090

Following gene: 162147087

Centisome position: 32.8

GC content: 72.37

Gene sequence:

>807_bases
ATGATCCCTGATTTTTCCGAAGCCGAAATCCAGCGCTACGCCCGCCACATCCTGCTGCCCGAGATCGGCGGCACCGGCCA
GGCGGCGCTGCGCGCGGCCAGCGTGCTGATCGTCGGCGCGGGCGGCCTGGGGTCGCCGCTGGGCCTGTACCTGGCGGCGG
CGGGCGTGGGACGGATCGGGCTGGTCGATGACGACGTGGTGGACCTGTCGAACCTGCAGCGCCAGATCGCCCATACCACC
GGGCGGATCGGCCAGCGCAAGGTCGAGTCGGCCGCCGAGGCGATGCGCGCGGTCAACCCGCTGGTGCGGGTCGAGCCCCA
TGCGACGCGCCTGGATGCCGGCAATGCCCGGGCACTGGTCGGGGGCTACGACCTGGTCTGCGACGGCAGCGATAATTTCC
GCACCCGCTACCTGGTCGCCGATGCCTGCGCGCTGGAGCGGCGGACCCTGGTATCGGCCGCCGTGCTGCGGTTCGAGGGG
CAGATATCCACCTTCCGGCCGCATCGCGGCGGGCCGTGCTATCGCTGCCTGTATCCCGCCCCCCCGCAGGACGGCGCGGT
GCCGTCCTGCGCCGAGGCCGGCGTGTTCGGCGCCGTGACCGGGGTCATGGGCACGCTGCAGGCAACCGAGGCGCTGAAGG
AGATCCTGGAGATCGGCGAGAGCCTGGACGGACGGCTGCTGGTCTGGGACGCGCTGGCGGCGCGGTTCCACACCGTCCGC
CTGGCGCCGGACCCCGATTGCGCGCTGTGCGGCCCGCACGCCAGCATCCATGACCTGTCGGCGCATGGGGCCGCCGATGT
CCGCTGA

Upstream 100 bases:

>100_bases
CGATAAACATGCCCGACATGCATGTTTATCATGCCGGGTGATACAAATTGTTACAAACAGACAGGTCGCGCGCCATAATC
CTGCGAACGGACCGGACCCC

Downstream 100 bases:

>100_bases
GCCGGGGCACGCCGAGGCGGGACAGGAGGGCCTGGCCATCCTGCTGCTGGATGGCGGGTACGAGCGCGCGCATTATGCCC
TGGTCCTGGCCGCCGGGGCG

Product: molybdopterin biosynthesis protein moeB

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MIPDFSEAEIQRYARHILLPEIGGTGQAALRAASVLIVGAGGLGSPLGLYLAAAGVGRIGLVDDDVVDLSNLQRQIAHTT
GRIGQRKVESAAEAMRAVNPLVRVEPHATRLDAGNARALVGGYDLVCDGSDNFRTRYLVADACALERRTLVSAAVLRFEG
QISTFRPHRGGPCYRCLYPAPPQDGAVPSCAEAGVFGAVTGVMGTLQATEALKEILEIGESLDGRLLVWDALAARFHTVR
LAPDPDCALCGPHASIHDLSAHGAADVR

Sequences:

>Translated_268_residues
MIPDFSEAEIQRYARHILLPEIGGTGQAALRAASVLIVGAGGLGSPLGLYLAAAGVGRIGLVDDDVVDLSNLQRQIAHTT
GRIGQRKVESAAEAMRAVNPLVRVEPHATRLDAGNARALVGGYDLVCDGSDNFRTRYLVADACALERRTLVSAAVLRFEG
QISTFRPHRGGPCYRCLYPAPPQDGAVPSCAEAGVFGAVTGVMGTLQATEALKEILEIGESLDGRLLVWDALAARFHTVR
LAPDPDCALCGPHASIHDLSAHGAADVR
>Mature_268_residues
MIPDFSEAEIQRYARHILLPEIGGTGQAALRAASVLIVGAGGLGSPLGLYLAAAGVGRIGLVDDDVVDLSNLQRQIAHTT
GRIGQRKVESAAEAMRAVNPLVRVEPHATRLDAGNARALVGGYDLVCDGSDNFRTRYLVADACALERRTLVSAAVLRFEG
QISTFRPHRGGPCYRCLYPAPPQDGAVPSCAEAGVFGAVTGVMGTLQATEALKEILEIGESLDGRLLVWDALAARFHTVR
LAPDPDCALCGPHASIHDLSAHGAADVR

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=256, Percent_Identity=51.5625, Blast_Score=214, Evalue=5e-56,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=41.2, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87082356, Length=249, Percent_Identity=39.3574297188755, Blast_Score=141, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17540406, Length=253, Percent_Identity=41.897233201581, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI193203301, Length=161, Percent_Identity=27.3291925465839, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=257, Percent_Identity=42.0233463035019, Blast_Score=196, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24582879, Length=256, Percent_Identity=44.140625, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28192; Mature: 28192

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPDFSEAEIQRYARHILLPEIGGTGQAALRAASVLIVGAGGLGSPLGLYLAAAGVGRIG
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCCC
LVDDDVVDLSNLQRQIAHTTGRIGQRKVESAAEAMRAVNPLVRVEPHATRLDAGNARALV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCEEEE
GGYDLVCDGSDNFRTRYLVADACALERRTLVSAAVLRFEGQISTFRPHRGGPCYRCLYPA
CCEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
PPQDGAVPSCAEAGVFGAVTGVMGTLQATEALKEILEIGESLDGRLLVWDALAARFHTVR
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHEEEE
LAPDPDCALCGPHASIHDLSAHGAADVR
ECCCCCCCEECCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MIPDFSEAEIQRYARHILLPEIGGTGQAALRAASVLIVGAGGLGSPLGLYLAAAGVGRIG
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCCC
LVDDDVVDLSNLQRQIAHTTGRIGQRKVESAAEAMRAVNPLVRVEPHATRLDAGNARALV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCEEEE
GGYDLVCDGSDNFRTRYLVADACALERRTLVSAAVLRFEGQISTFRPHRGGPCYRCLYPA
CCEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
PPQDGAVPSCAEAGVFGAVTGVMGTLQATEALKEILEIGESLDGRLLVWDALAARFHTVR
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHEEEE
LAPDPDCALCGPHASIHDLSAHGAADVR
ECCCCCCCEECCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]