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The map label for this gene is caiD [C]

Identifier: 162147038

GI number: 162147038

Start: 1238501

End: 1239550

Strand: Reverse

Name: caiD [C]

Synonym: GDI_1243

Alternate gene names: 162147038

Gene position: 1239550-1238501 (Counterclockwise)

Preceding gene: 162147040

Following gene: 162147037

Centisome position: 31.43

GC content: 72.95

Gene sequence:

>1050_bases
ATGGATGCCGCCATGGACGCCGACACGCTGCTGATCACCCGCCAGGGCCGCCTGGGGCGGATGACGCTGAACCGGCCGAA
GGCGCTGAATGCGCTGGACAGGACGCTGTTCGCGCGCATCGCCGCCTGCCTGGCGGACTGGCGGGAGGACCCGTCGGTCG
AAACCGTGCTGATCGACAGTTCCAGCCCGCGCGCCTTCTGCGCCGGGGGGGACCTGCGGGCCATCCATGCCACGCTGGGC
GCCGCCGGTCCGGCGGCGGCGGCGTCGATCTTCCGCGACGGCTACCGGCTGGTATCGGTCCTGGCGGGGTATCCCAAGGC
CGTGGTCTCGTTCATGGACGGGATCACGATGGGCGGCGGGGTGGGACTGGGCGGCCATGTGCGGCACCGCATCGTCACCG
AACGGGCGGTGGTCGCCATGCCCGAGACCGCCATCGGCCTGACGCCGGACGCGGGCGGGTCGTATATCCTGTCGCGCGCG
CCGGGCCTGTCCGGCCTGCGCCTGGCCCTGACCGGCGGCCGGATGCAGGGCGGCGAGGCCGTGGCGGCGGGCTTCGCCGA
CCGGATGCTGGCGGCGGCGGACCTGCCGGCCCTGGCCGAAGGCCTGGCCCGCCGGCCGGCCGGCCAGGTCGTGGACATGG
CCCCCGCCGCGCCACGGGACGGGGCGTGTCCCGACCATGCGGCGATCAATACGCTGTACGACGCGCCGGACGTGGCGACG
ATCATCGACCGCCTGGACCGCCACGGCGCCCCCTGGGCCGAGGCGGACCGCGCGGCGTTGCGGCAGGCATCGCCGCTGTC
GCTGCGCGTGACGTTCCGCGCGTTTCATGCCGCGCGGCGGCTGCCGGACCTGGATACGGTGCTGGAACAGGAATACCGGC
TGATCGCCAGCCTGCTGGAGCAGCCCGATTTCGCCGAGGGCGTGCGGGCCAAGATCGTGGACAAGGACAACGCCCCGCGC
TGGATGGACAAGGCGGCATGGAGCGATGCGGCGATCGAGGCGTTCTTCGCCCCACGAGCGGACTCGTTGGACCTGCCGAT
CTTTTCCTGA

Upstream 100 bases:

>100_bases
GTCGTCCGTGTCCGTCTGGTCCGTTTCGACGGGGCGACACACCAACGCCGCATCTTCTGTCATATTATCGCGCAAGGGAA
AACAGGAGGAAACCACCATC

Downstream 100 bases:

>100_bases
CTCGTCTCAAGAGTTTTTGGTGACACAAGATGCCCCTTTCACCCACCTACCGCCCCGCCCGCAATCACCTGACCCTGGGC
GATGCGTTCTACGACCCGGT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDAAMDADTLLITRQGRLGRMTLNRPKALNALDRTLFARIAACLADWREDPSVETVLIDSSSPRAFCAGGDLRAIHATLG
AAGPAAAASIFRDGYRLVSVLAGYPKAVVSFMDGITMGGGVGLGGHVRHRIVTERAVVAMPETAIGLTPDAGGSYILSRA
PGLSGLRLALTGGRMQGGEAVAAGFADRMLAAADLPALAEGLARRPAGQVVDMAPAAPRDGACPDHAAINTLYDAPDVAT
IIDRLDRHGAPWAEADRAALRQASPLSLRVTFRAFHAARRLPDLDTVLEQEYRLIASLLEQPDFAEGVRAKIVDKDNAPR
WMDKAAWSDAAIEAFFAPRADSLDLPIFS

Sequences:

>Translated_349_residues
MDAAMDADTLLITRQGRLGRMTLNRPKALNALDRTLFARIAACLADWREDPSVETVLIDSSSPRAFCAGGDLRAIHATLG
AAGPAAAASIFRDGYRLVSVLAGYPKAVVSFMDGITMGGGVGLGGHVRHRIVTERAVVAMPETAIGLTPDAGGSYILSRA
PGLSGLRLALTGGRMQGGEAVAAGFADRMLAAADLPALAEGLARRPAGQVVDMAPAAPRDGACPDHAAINTLYDAPDVAT
IIDRLDRHGAPWAEADRAALRQASPLSLRVTFRAFHAARRLPDLDTVLEQEYRLIASLLEQPDFAEGVRAKIVDKDNAPR
WMDKAAWSDAAIEAFFAPRADSLDLPIFS
>Mature_349_residues
MDAAMDADTLLITRQGRLGRMTLNRPKALNALDRTLFARIAACLADWREDPSVETVLIDSSSPRAFCAGGDLRAIHATLG
AAGPAAAASIFRDGYRLVSVLAGYPKAVVSFMDGITMGGGVGLGGHVRHRIVTERAVVAMPETAIGLTPDAGGSYILSRA
PGLSGLRLALTGGRMQGGEAVAAGFADRMLAAADLPALAEGLARRPAGQVVDMAPAAPRDGACPDHAAINTLYDAPDVAT
IIDRLDRHGAPWAEADRAALRQASPLSLRVTFRAFHAARRLPDLDTVLEQEYRLIASLLEQPDFAEGVRAKIVDKDNAPR
WMDKAAWSDAAIEAFFAPRADSLDLPIFS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=327, Percent_Identity=37.0030581039755, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI37594469, Length=300, Percent_Identity=36.3333333333333, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI194097323, Length=210, Percent_Identity=30.4761904761905, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI221142681, Length=213, Percent_Identity=30.0469483568075, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788682, Length=205, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=29.4820717131474, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787659, Length=297, Percent_Identity=26.2626262626263, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=352, Percent_Identity=34.6590909090909, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI25144160, Length=352, Percent_Identity=34.6590909090909, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17558304, Length=186, Percent_Identity=28.494623655914, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508951, Length=186, Percent_Identity=29.5698924731183, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=186, Percent_Identity=29.5698924731183, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=186, Percent_Identity=29.5698924731183, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=209, Percent_Identity=27.7511961722488, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=203, Percent_Identity=28.0788177339901, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=201, Percent_Identity=31.8407960199005, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=189, Percent_Identity=29.1005291005291, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=374, Percent_Identity=28.3422459893048, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571730, Length=351, Percent_Identity=36.4672364672365, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI28571729, Length=351, Percent_Identity=36.4672364672365, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 36898; Mature: 36898

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAMDADTLLITRQGRLGRMTLNRPKALNALDRTLFARIAACLADWREDPSVETVLIDS
CCCCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
SSPRAFCAGGDLRAIHATLGAAGPAAAASIFRDGYRLVSVLAGYPKAVVSFMDGITMGGG
CCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
VGLGGHVRHRIVTERAVVAMPETAIGLTPDAGGSYILSRAPGLSGLRLALTGGRMQGGEA
CCCCHHHHHHHHHHHHHEECCCHHCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCHH
VAAGFADRMLAAADLPALAEGLARRPAGQVVDMAPAAPRDGACPDHAAINTLYDAPDVAT
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCHHHH
IIDRLDRHGAPWAEADRAALRQASPLSLRVTFRAFHAARRLPDLDTVLEQEYRLIASLLE
HHHHHHHCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
QPDFAEGVRAKIVDKDNAPRWMDKAAWSDAAIEAFFAPRADSLDLPIFS
CCCHHCCCEEEEECCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDAAMDADTLLITRQGRLGRMTLNRPKALNALDRTLFARIAACLADWREDPSVETVLIDS
CCCCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
SSPRAFCAGGDLRAIHATLGAAGPAAAASIFRDGYRLVSVLAGYPKAVVSFMDGITMGGG
CCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
VGLGGHVRHRIVTERAVVAMPETAIGLTPDAGGSYILSRAPGLSGLRLALTGGRMQGGEA
CCCCHHHHHHHHHHHHHEECCCHHCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCHH
VAAGFADRMLAAADLPALAEGLARRPAGQVVDMAPAAPRDGACPDHAAINTLYDAPDVAT
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCHHHH
IIDRLDRHGAPWAEADRAALRQASPLSLRVTFRAFHAARRLPDLDTVLEQEYRLIASLLE
HHHHHHHCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
QPDFAEGVRAKIVDKDNAPRWMDKAAWSDAAIEAFFAPRADSLDLPIFS
CCCHHCCCEEEEECCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA