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The map label for this gene is ribH [H]

Identifier: 162146946

GI number: 162146946

Start: 1147109

End: 1147591

Strand: Reverse

Name: ribH [H]

Synonym: GDI_1151

Alternate gene names: 162146946

Gene position: 1147591-1147109 (Counterclockwise)

Preceding gene: 162146947

Following gene: 162146945

Centisome position: 29.1

GC content: 66.87

Gene sequence:

>483_bases
ATGAGCACCAATACGCCGTCTTCCTCACCCGACCTGACCTTCGCGCGGCCGCCGCGCCTGGCGATCGTGGTCAGCCGCTT
CAACGAAACCGTCACCCACGGCCTGCGCGACGGGGCGCTGGAATGGCTGGGCGAGCACGGCATCACCGTCGCGGACGACG
ACGTACTGTATGCCCCGGGCGCCTACGAACTGCCGCTTCTGGCCCAGACGCTGGCCCGTACCGGCCGCTATGAAGGGGTG
ATCTGCCTGGGCTGCGTGATCAAGGGCGACACGGCGCATTTCGAATTCATCAGCCTGGGCGCCGCGATCGGCCTGATGCA
GGCCTCGCTGGCGACCGAGATCCCGGTCGCGTTCGGGGTGCTGACCACCTACACCGACGAACAGGCCGTGCTGCGCTCGC
GCACCGACGAACATAACAAGGGGCGCGAGGCCGCGGCCGCCTGCGTCGAAAGTCTGGCCTTGATACGCAAAATCAAGGGC
TGA

Upstream 100 bases:

>100_bases
TCTGGACGCCAAGCGTACCCGGATGGGACACCATCTCTGCTCCACCGTCAGCGCGGCGGCCGAGTGAGGCGCCGCAGACC
ACCGACCGGATAGAATCGAC

Downstream 100 bases:

>100_bases
TACGCTGGCCTGACACGGGTCGGCGCCACCGCCGGCCCATGGTCCCGGGGGGCCGGGCGGCGGGGGCGCGGAATGAAGCT
GGTGACGTTGACGGCCGGAC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase 1; Lumazine synthase 1; Riboflavin synthase 1 beta chain [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSTNTPSSSPDLTFARPPRLAIVVSRFNETVTHGLRDGALEWLGEHGITVADDDVLYAPGAYELPLLAQTLARTGRYEGV
ICLGCVIKGDTAHFEFISLGAAIGLMQASLATEIPVAFGVLTTYTDEQAVLRSRTDEHNKGREAAAACVESLALIRKIKG

Sequences:

>Translated_160_residues
MSTNTPSSSPDLTFARPPRLAIVVSRFNETVTHGLRDGALEWLGEHGITVADDDVLYAPGAYELPLLAQTLARTGRYEGV
ICLGCVIKGDTAHFEFISLGAAIGLMQASLATEIPVAFGVLTTYTDEQAVLRSRTDEHNKGREAAAACVESLALIRKIKG
>Mature_159_residues
STNTPSSSPDLTFARPPRLAIVVSRFNETVTHGLRDGALEWLGEHGITVADDDVLYAPGAYELPLLAQTLARTGRYEGVI
CLGCVIKGDTAHFEFISLGAAIGLMQASLATEIPVAFGVLTTYTDEQAVLRSRTDEHNKGREAAAACVESLALIRKIKG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=143, Percent_Identity=48.2517482517483, Blast_Score=130, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324429, Length=152, Percent_Identity=34.8684210526316, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 17101; Mature: 16969

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNTPSSSPDLTFARPPRLAIVVSRFNETVTHGLRDGALEWLGEHGITVADDDVLYAPG
CCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCC
AYELPLLAQTLARTGRYEGVICLGCVIKGDTAHFEFISLGAAIGLMQASLATEIPVAFGV
CCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTYTDEQAVLRSRTDEHNKGREAAAACVESLALIRKIKG
HHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STNTPSSSPDLTFARPPRLAIVVSRFNETVTHGLRDGALEWLGEHGITVADDDVLYAPG
CCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCC
AYELPLLAQTLARTGRYEGVICLGCVIKGDTAHFEFISLGAAIGLMQASLATEIPVAFGV
CCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTYTDEQAVLRSRTDEHNKGREAAAACVESLALIRKIKG
HHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]