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The map label for this gene is nodT [H]

Identifier: 162146907

GI number: 162146907

Start: 1099453

End: 1100928

Strand: Reverse

Name: nodT [H]

Synonym: GDI_1106

Alternate gene names: 162146907

Gene position: 1100928-1099453 (Counterclockwise)

Preceding gene: 162146912

Following gene: 162146906

Centisome position: 27.91

GC content: 61.65

Gene sequence:

>1476_bases
ATGAACCTTTCGCTTCCCGCACCCAAACTGAACGCCAATCGCACGAGGCACAGGGGAGTGGCTCCCGCAGTAGCCTTGAC
CATGACGCTCATGACAACGGCCTGCGCGGTCGGCCCCAACTATCATGCACCCGATACGCATCTTCAGCCCTTCCACAGTG
CTGCCGCTGTCGACATGCGACAAGTCACCTCGACTCCACCGTTAGATACTTGGTGGGAGGGATTTCACGATCCCGAACTA
GTCCGCATAGAACAGCGTGTCCTGACCCAGAACCTTGATCTCGCGGCCGCCATAGCGCGCGTCCGCCAATCTCGAGGTGC
CGCTGAGGCCGCCACGGCGCGCCTGCTCCCCACTCTGGATTTCAACCCGCAGGCCTCCGCGAACCGGCTGTCGCAGGAGG
GGCTGATCGGCCATGTCGTTCGCACCATACCGAGCTTTCACCGCGATTATCGCACTTATGACGTAAGTGGCGCTGCGAGC
TGGGAAATCGACCTGTTCGGCGGCCTACGACGTGGGCAGGAAGCCGCACGTGACGAAGCGGAAGCCGCACAAATGGAGCG
TGTGGGGGAGCGTATCATGATCGCCGCCGACGCGGCAGACGCCTATTTCCAAATCCGCGGAGATCAAGCCCGCCTGGCCG
TCGCGGAAAAACAGATCACAGTGGACGCCCATCTACTGGAACTGGTGCGTCAACGGCGAACAAGCGGCGTTTCGAATGAG
CGGGAACTGGCCCAGGCCGAGGCGTTACTGCAATCGGCGCGCCAGACCGTGCCGCTGCTCCGCATCGCACTCGAAGCGCA
GCTCAATCGGCTCGACGTACTAATGGGCGTGCAGCCCGGTACCTATGCCGCCGAACTGGGAACGCCGTCTGAAATTCCGG
CCATCCCTGCCATCGGCGGTACCAACAAACCCACGGACGTGCTGCGCCGCCGACCGGACATTCTGGCTGCTGAACGCAGA
CTGGCGGCATCAAATGCGAGGATAGGCGCGGCACTCGGCGACTATTACCCCAAGCTCTCTCTTTCGGGCATCCTCGGCTT
TCAAAGCATCAATCCTCAGCATCTATTTACGGCACCGGGATTCCAGGCTGTCGGATCAGGCGCCATTCGCTGGCGGATCT
TCGATTTCGGCAAGATCGACGCCGAGGTACAGCAAGCCCGTGGCGCCAATACCGAGGCCCTGGCGCGCTACCGGTTGACG
GTCCTACATGCGGCCGAAGATGTAAAAAATTCTTTCACGACCCTGGTACAGACGGAGCAACGCAGTGGCGAATTGCAGAC
TGAAGTCGCCTCGCTGACCCGTGCACGCGATCTTTCCCAACAATCCTTCCAGGCGGGTGTCATCCCCTTGACTGATGTGC
TCGACGCTGAACGGCAGCTTCTCGACTCGCAGGACCAACTGGCCCTTAACCGGGCGAACCCGGGGCGCGCGGCGGTTAGC
TCCTTCAGAGCCTTGGGGGGCGGCTGGCCCACATGA

Upstream 100 bases:

>100_bases
GGACGTCGGTTATAAATTGACAACGAGTGACGTATGTGTATATCGGTCACTAGACAACGCCGGGACGTCGCGTGTCCGGG
CTGATCGAAAGTCGACCACC

Downstream 100 bases:

>100_bases
GAGCGCTGATCAACCGAGCATGGCAGAGGGTTGGCTCGTTTCTCTTCTGCATACTTATTACTCTGCTTGTTCGTGGGGCA
GAGATATTCGCACGTCCCCG

Product: outer membrane factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNLSLPAPKLNANRTRHRGVAPAVALTMTLMTTACAVGPNYHAPDTHLQPFHSAAAVDMRQVTSTPPLDTWWEGFHDPEL
VRIEQRVLTQNLDLAAAIARVRQSRGAAEAATARLLPTLDFNPQASANRLSQEGLIGHVVRTIPSFHRDYRTYDVSGAAS
WEIDLFGGLRRGQEAARDEAEAAQMERVGERIMIAADAADAYFQIRGDQARLAVAEKQITVDAHLLELVRQRRTSGVSNE
RELAQAEALLQSARQTVPLLRIALEAQLNRLDVLMGVQPGTYAAELGTPSEIPAIPAIGGTNKPTDVLRRRPDILAAERR
LAASNARIGAALGDYYPKLSLSGILGFQSINPQHLFTAPGFQAVGSGAIRWRIFDFGKIDAEVQQARGANTEALARYRLT
VLHAAEDVKNSFTTLVQTEQRSGELQTEVASLTRARDLSQQSFQAGVIPLTDVLDAERQLLDSQDQLALNRANPGRAAVS
SFRALGGGWPT

Sequences:

>Translated_491_residues
MNLSLPAPKLNANRTRHRGVAPAVALTMTLMTTACAVGPNYHAPDTHLQPFHSAAAVDMRQVTSTPPLDTWWEGFHDPEL
VRIEQRVLTQNLDLAAAIARVRQSRGAAEAATARLLPTLDFNPQASANRLSQEGLIGHVVRTIPSFHRDYRTYDVSGAAS
WEIDLFGGLRRGQEAARDEAEAAQMERVGERIMIAADAADAYFQIRGDQARLAVAEKQITVDAHLLELVRQRRTSGVSNE
RELAQAEALLQSARQTVPLLRIALEAQLNRLDVLMGVQPGTYAAELGTPSEIPAIPAIGGTNKPTDVLRRRPDILAAERR
LAASNARIGAALGDYYPKLSLSGILGFQSINPQHLFTAPGFQAVGSGAIRWRIFDFGKIDAEVQQARGANTEALARYRLT
VLHAAEDVKNSFTTLVQTEQRSGELQTEVASLTRARDLSQQSFQAGVIPLTDVLDAERQLLDSQDQLALNRANPGRAAVS
SFRALGGGWPT
>Mature_491_residues
MNLSLPAPKLNANRTRHRGVAPAVALTMTLMTTACAVGPNYHAPDTHLQPFHSAAAVDMRQVTSTPPLDTWWEGFHDPEL
VRIEQRVLTQNLDLAAAIARVRQSRGAAEAATARLLPTLDFNPQASANRLSQEGLIGHVVRTIPSFHRDYRTYDVSGAAS
WEIDLFGGLRRGQEAARDEAEAAQMERVGERIMIAADAADAYFQIRGDQARLAVAEKQITVDAHLLELVRQRRTSGVSNE
RELAQAEALLQSARQTVPLLRIALEAQLNRLDVLMGVQPGTYAAELGTPSEIPAIPAIGGTNKPTDVLRRRPDILAAERR
LAASNARIGAALGDYYPKLSLSGILGFQSINPQHLFTAPGFQAVGSGAIRWRIFDFGKIDAEVQQARGANTEALARYRLT
VLHAAEDVKNSFTTLVQTEQRSGELQTEVASLTRARDLSQQSFQAGVIPLTDVLDAERQLLDSQDQLALNRANPGRAAVS
SFRALGGGWPT

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=470, Percent_Identity=25.3191489361702, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI2367348, Length=483, Percent_Identity=22.5672877846791, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53397; Mature: 53397

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSLPAPKLNANRTRHRGVAPAVALTMTLMTTACAVGPNYHAPDTHLQPFHSAAAVDMR
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
QVTSTPPLDTWWEGFHDPELVRIEQRVLTQNLDLAAAIARVRQSRGAAEAATARLLPTLD
HHCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
FNPQASANRLSQEGLIGHVVRTIPSFHRDYRTYDVSGAASWEIDLFGGLRRGQEAARDEA
CCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCHHHHHHHHHHHH
EAAQMERVGERIMIAADAADAYFQIRGDQARLAVAEKQITVDAHLLELVRQRRTSGVSNE
HHHHHHHCCCEEEEEECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCH
RELAQAEALLQSARQTVPLLRIALEAQLNRLDVLMGVQPGTYAAELGTPSEIPAIPAIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCCCCCCC
TNKPTDVLRRRPDILAAERRLAASNARIGAALGDYYPKLSLSGILGFQSINPQHLFTAPG
CCCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHEECCCCCCCEEEECCC
FQAVGSGAIRWRIFDFGKIDAEVQQARGANTEALARYRLTVLHAAEDVKNSFTTLVQTEQ
HHHHCCCEEEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGELQTEVASLTRARDLSQQSFQAGVIPLTDVLDAERQLLDSQDQLALNRANPGRAAVS
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHH
SFRALGGGWPT
HHHHHCCCCCC
>Mature Secondary Structure
MNLSLPAPKLNANRTRHRGVAPAVALTMTLMTTACAVGPNYHAPDTHLQPFHSAAAVDMR
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
QVTSTPPLDTWWEGFHDPELVRIEQRVLTQNLDLAAAIARVRQSRGAAEAATARLLPTLD
HHCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
FNPQASANRLSQEGLIGHVVRTIPSFHRDYRTYDVSGAASWEIDLFGGLRRGQEAARDEA
CCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCHHHHHHHHHHHH
EAAQMERVGERIMIAADAADAYFQIRGDQARLAVAEKQITVDAHLLELVRQRRTSGVSNE
HHHHHHHCCCEEEEEECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCH
RELAQAEALLQSARQTVPLLRIALEAQLNRLDVLMGVQPGTYAAELGTPSEIPAIPAIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCCCCCCC
TNKPTDVLRRRPDILAAERRLAASNARIGAALGDYYPKLSLSGILGFQSINPQHLFTAPG
CCCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHEECCCCCCCEEEECCC
FQAVGSGAIRWRIFDFGKIDAEVQQARGANTEALARYRLTVLHAAEDVKNSFTTLVQTEQ
HHHHCCCEEEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGELQTEVASLTRARDLSQQSFQAGVIPLTDVLDAERQLLDSQDQLALNRANPGRAAVS
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHH
SFRALGGGWPT
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]