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The map label for this gene is lrrA [H]

Identifier: 162146825

GI number: 162146825

Start: 1021979

End: 1022740

Strand: Direct

Name: lrrA [H]

Synonym: GDI_1007

Alternate gene names: 162146825

Gene position: 1021979-1022740 (Clockwise)

Preceding gene: 162146824

Following gene: 162146827

Centisome position: 25.91

GC content: 61.29

Gene sequence:

>762_bases
ATGCATCTCACCGAACTTCGTTATCTGCTGACGGTTATCGAAGCCGGAAGTTTCGGTCGGGCCGCCCAGTCCTTGCACCT
CCAGGTATCGACACTCAGCCGTGCCATCAGCCGGCTGGAAGACAGGCTGGGCGTGACGCTCCTGGAGCGGACGCCGGCCG
GGATCCGAGCCACCGCGTCGGGACGACTGGCGACACGCTATATCCGCCGTGTGCTTCATGAAACGCATGCAATGGAGGAC
ACACTGGCTCGCGGCAGTGCCGGAGAGAAGGGCGAGATCCGCCTGGGCCTGCATCTTCCGCCGATCAGTCCTGTTCTGAT
GGCCCTGCTACGGGAATGGCGCATGTCCTATCCGGGCGTCATCGTTGCACCCTGTGAGTTTGGCGAAGAAAGCCTGCACG
CGGCCCTGACGGGCTGCCGGGTCGACGTCGCCCTGATTCCGGATTGCCTGCTGCAGAACCACGAAGCGGCCGTGCGAGTC
TATGCCGAACCTCTCGTGGCCGTGCTACCGGCTGGTCATCACCTGATTGGGCAAAATATGCTGCACTGGGCGAGTCTGGA
GAACGAGATCCTTCTGCTCGGGGCCTCGGGCAAGGGGGCCATCTGCCGCGATTTCTATATGGCTCGGCTGCCTGGTGCCC
GATTACACATCCTTGAAGCCAGCATCCTGAGCGTGCTCGCCTTCGTGCGCGCGGGATTTGGTATCACAATCGCCGCCCAA
GCCTATTCCACCTTGAAGTGTAGAAGTTTGCACTTAATCTGA

Upstream 100 bases:

>100_bases
AGGGAGGAGCGTCAGCGTCCGCAAATGTGCTCTGGAAGCGGTCATAAGCTGGACGCCGATTGAGGATCGGCATTACTCAT
AGCCAACGGTGACCGGACTC

Downstream 100 bases:

>100_bases
CGGACGGCTTGAAGTGGCCGGCGTGGATGCTACGCGTTCATGTGGTGTTCGACGTGGCGCCCGATATCTTTTTCGCGGGC
GTGGTGGGCTGCGTCAAGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MHLTELRYLLTVIEAGSFGRAAQSLHLQVSTLSRAISRLEDRLGVTLLERTPAGIRATASGRLATRYIRRVLHETHAMED
TLARGSAGEKGEIRLGLHLPPISPVLMALLREWRMSYPGVIVAPCEFGEESLHAALTGCRVDVALIPDCLLQNHEAAVRV
YAEPLVAVLPAGHHLIGQNMLHWASLENEILLLGASGKGAICRDFYMARLPGARLHILEASILSVLAFVRAGFGITIAAQ
AYSTLKCRSLHLI

Sequences:

>Translated_253_residues
MHLTELRYLLTVIEAGSFGRAAQSLHLQVSTLSRAISRLEDRLGVTLLERTPAGIRATASGRLATRYIRRVLHETHAMED
TLARGSAGEKGEIRLGLHLPPISPVLMALLREWRMSYPGVIVAPCEFGEESLHAALTGCRVDVALIPDCLLQNHEAAVRV
YAEPLVAVLPAGHHLIGQNMLHWASLENEILLLGASGKGAICRDFYMARLPGARLHILEASILSVLAFVRAGFGITIAAQ
AYSTLKCRSLHLI
>Mature_253_residues
MHLTELRYLLTVIEAGSFGRAAQSLHLQVSTLSRAISRLEDRLGVTLLERTPAGIRATASGRLATRYIRRVLHETHAMED
TLARGSAGEKGEIRLGLHLPPISPVLMALLREWRMSYPGVIVAPCEFGEESLHAALTGCRVDVALIPDCLLQNHEAAVRV
YAEPLVAVLPAGHHLIGQNMLHWASLENEILLLGASGKGAICRDFYMARLPGARLHILEASILSVLAFVRAGFGITIAAQ
AYSTLKCRSLHLI

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=28.2786885245902, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787879, Length=264, Percent_Identity=26.8939393939394, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786401, Length=119, Percent_Identity=34.453781512605, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI157672245, Length=230, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789639, Length=120, Percent_Identity=34.1666666666667, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 27559; Mature: 27559

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLTELRYLLTVIEAGSFGRAAQSLHLQVSTLSRAISRLEDRLGVTLLERTPAGIRATAS
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEECCC
GRLATRYIRRVLHETHAMEDTLARGSAGEKGEIRLGLHLPPISPVLMALLREWRMSYPGV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCE
IVAPCEFGEESLHAALTGCRVDVALIPDCLLQNHEAAVRVYAEPLVAVLPAGHHLIGQNM
EEEECCCCHHHHHHHHHCCEEEHHHHHHHHHCCCHHHEEEHHHHHHHHHCCCCHHHHHHH
LHWASLENEILLLGASGKGAICRDFYMARLPGARLHILEASILSVLAFVRAGFGITIAAQ
HHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEH
AYSTLKCRSLHLI
HHHHHHHEEEECC
>Mature Secondary Structure
MHLTELRYLLTVIEAGSFGRAAQSLHLQVSTLSRAISRLEDRLGVTLLERTPAGIRATAS
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEECCC
GRLATRYIRRVLHETHAMEDTLARGSAGEKGEIRLGLHLPPISPVLMALLREWRMSYPGV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCE
IVAPCEFGEESLHAALTGCRVDVALIPDCLLQNHEAAVRVYAEPLVAVLPAGHHLIGQNM
EEEECCCCHHHHHHHHHCCEEEHHHHHHHHHCCCHHHEEEHHHHHHHHHCCCCHHHHHHH
LHWASLENEILLLGASGKGAICRDFYMARLPGARLHILEASILSVLAFVRAGFGITIAAQ
HHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEH
AYSTLKCRSLHLI
HHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8661945 [H]