Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 162146823

GI number: 162146823

Start: 1020052

End: 1020969

Strand: Reverse

Name: yafC [H]

Synonym: GDI_1005

Alternate gene names: 162146823

Gene position: 1020969-1020052 (Counterclockwise)

Preceding gene: 162146826

Following gene: 162146820

Centisome position: 25.89

GC content: 63.62

Gene sequence:

>918_bases
ATGGAACAATCGCCAGTCTCACTGGAGCGGATGCGGACCTTCGTGCGGGTCGCCGAACGTGGCAATCTGGCGGCCGTTGC
CCGTGAAACCGGTGCCGGGCAGTCGACGATCACGCGGCACCTGCGCGAGCTTGAGGACGCTCTGGGCGTCTCACTGCTGA
CGCGGACGACGCGTCGTACGGCGCTGACGGATGAAGGAACGCGCTATTACGCGCATTGTGTGCAGATACTCTCTCTCGTC
GAGCAGGCGAGCCAGGAGATGCGCGAGACGCGGCAGGCAACGGCCGGAACGGTACGCATCTCCTGCACCGGCGCGCTGGG
TGTCCTGCATGTCAGCCAGCTCATTTATGCCTTTCAAGACCAGAATCCGGGAATACGGGTGGAATTCGGCCTGACGGATG
AGCGGATCGATCTGGTGCGGGATGGGGTCGATATTGCCATCCGTCTCGGTCCCCTGAGCGATTGCGCGATGAAACTGCGT
TCCCTGGGGGAGAGCGAGCGCCTGTTGGTCGCATCGCCCGAATGGCTACACCGTACTGGGCCGGTGCGGCGACCGGTGGA
TCTGCGTGATCGCGAAGGGGTGCGAATGTCGCGCGTGCATGGATCGGACCGACTGGTCCTGCGGAGCGCCAGGGGTAGAA
ACCATGTCGTGCCGTTTCATGGCCGTTTGATCGTCGATCATGGTTTGGCGGCGCGGGAGGCGTTTCTGGCGGGCAGGGGT
TTCGGCCCGGCCCATCGTTGGCTGGTGGAAGACTGCTTGCAGGACGGTCGACTGGTGCCGCTTCTTCCAGACTACACGTT
GCCGTCGGTGCCGCTGAGCATGCTTATCGCGCCTGAACGGACGAATCTGGCCAGGATCCGTCTCTGCGTGGAGTTCCTGG
CCGAACGGGTCGGCGGAATACCAGGCATCAGCCGGTGA

Upstream 100 bases:

>100_bases
AGCGGACTCTCATTGCGTGGAAAATTTCGTTTCCCAACGAGATTACGCGATAGGCTATTCTTATCCCATATGGCGATGGC
GGAAGGGAGAATGCTGAAAT

Downstream 100 bases:

>100_bases
TCGTCGGGGAATTGGCGCGATTTTCCGCCTGCTTGCGCACGGCGGCCAACATGCGTCTGCGGATCAGTCCACTGACCGGA
CGGATGAGATACCAGTAGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MEQSPVSLERMRTFVRVAERGNLAAVARETGAGQSTITRHLRELEDALGVSLLTRTTRRTALTDEGTRYYAHCVQILSLV
EQASQEMRETRQATAGTVRISCTGALGVLHVSQLIYAFQDQNPGIRVEFGLTDERIDLVRDGVDIAIRLGPLSDCAMKLR
SLGESERLLVASPEWLHRTGPVRRPVDLRDREGVRMSRVHGSDRLVLRSARGRNHVVPFHGRLIVDHGLAAREAFLAGRG
FGPAHRWLVEDCLQDGRLVPLLPDYTLPSVPLSMLIAPERTNLARIRLCVEFLAERVGGIPGISR

Sequences:

>Translated_305_residues
MEQSPVSLERMRTFVRVAERGNLAAVARETGAGQSTITRHLRELEDALGVSLLTRTTRRTALTDEGTRYYAHCVQILSLV
EQASQEMRETRQATAGTVRISCTGALGVLHVSQLIYAFQDQNPGIRVEFGLTDERIDLVRDGVDIAIRLGPLSDCAMKLR
SLGESERLLVASPEWLHRTGPVRRPVDLRDREGVRMSRVHGSDRLVLRSARGRNHVVPFHGRLIVDHGLAAREAFLAGRG
FGPAHRWLVEDCLQDGRLVPLLPDYTLPSVPLSMLIAPERTNLARIRLCVEFLAERVGGIPGISR
>Mature_305_residues
MEQSPVSLERMRTFVRVAERGNLAAVARETGAGQSTITRHLRELEDALGVSLLTRTTRRTALTDEGTRYYAHCVQILSLV
EQASQEMRETRQATAGTVRISCTGALGVLHVSQLIYAFQDQNPGIRVEFGLTDERIDLVRDGVDIAIRLGPLSDCAMKLR
SLGESERLLVASPEWLHRTGPVRRPVDLRDREGVRMSRVHGSDRLVLRSARGRNHVVPFHGRLIVDHGLAAREAFLAGRG
FGPAHRWLVEDCLQDGRLVPLLPDYTLPSVPLSMLIAPERTNLARIRLCVEFLAERVGGIPGISR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=30.5084745762712, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=33.1081081081081, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=26.6666666666667, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=31.5972222222222, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789639, Length=258, Percent_Identity=28.6821705426357, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787128, Length=274, Percent_Identity=27.7372262773723, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1789173, Length=282, Percent_Identity=23.758865248227, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=221, Percent_Identity=26.6968325791855, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787601, Length=122, Percent_Identity=27.0491803278689, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787589, Length=272, Percent_Identity=23.8970588235294, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33887; Mature: 33887

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSPVSLERMRTFVRVAERGNLAAVARETGAGQSTITRHLRELEDALGVSLLTRTTRRT
CCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTDEGTRYYAHCVQILSLVEQASQEMRETRQATAGTVRISCTGALGVLHVSQLIYAFQD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHC
QNPGIRVEFGLTDERIDLVRDGVDIAIRLGPLSDCAMKLRSLGESERLLVASPEWLHRTG
CCCCEEEEECCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCEEEEECCHHHHHCC
PVRRPVDLRDREGVRMSRVHGSDRLVLRSARGRNHVVPFHGRLIVDHGLAAREAFLAGRG
CCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHCCC
FGPAHRWLVEDCLQDGRLVPLLPDYTLPSVPLSMLIAPERTNLARIRLCVEFLAERVGGI
CCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
PGISR
CCCCC
>Mature Secondary Structure
MEQSPVSLERMRTFVRVAERGNLAAVARETGAGQSTITRHLRELEDALGVSLLTRTTRRT
CCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTDEGTRYYAHCVQILSLVEQASQEMRETRQATAGTVRISCTGALGVLHVSQLIYAFQD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHC
QNPGIRVEFGLTDERIDLVRDGVDIAIRLGPLSDCAMKLRSLGESERLLVASPEWLHRTG
CCCCEEEEECCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCEEEEECCHHHHHCC
PVRRPVDLRDREGVRMSRVHGSDRLVLRSARGRNHVVPFHGRLIVDHGLAAREAFLAGRG
CCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHCCC
FGPAHRWLVEDCLQDGRLVPLLPDYTLPSVPLSMLIAPERTNLARIRLCVEFLAERVGGI
CCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
PGISR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]