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The map label for this gene is degP [H]

Identifier: 162146706

GI number: 162146706

Start: 900133

End: 901740

Strand: Direct

Name: degP [H]

Synonym: GDI_0884

Alternate gene names: 162146706

Gene position: 900133-901740 (Clockwise)

Preceding gene: 162146705

Following gene: 162146707

Centisome position: 22.82

GC content: 71.33

Gene sequence:

>1608_bases
ATGCCCCTGACCGTTCCGGTTTTCTTCCGTCCCTGTGCCGCCGTCGGGCTGGCGGCGGCCCTGTCCCTGATCGCGGGGGG
GGGCCTCCGGGCCGAACCGGCGGTGGTGCCGCATCCGGTCGCCCCAGCCGCGCCCGCCGCCCCTGCGGTCCCGCCCGTTA
CCGTGCCGCCGGTCCACCTGCCCGCGCCGGGGCGCGGCGCGCCCGACAGCTTCGCGGACCTCGCGGCGCGGCTGCTGCCC
GCCGTGGTCAACGTCTCGACCACCGAGACGGTCAAGCCCGGGGACCAGGACGGCGATTCCGACGGTGATGGTGGGGGCGA
GGATACGCCCCAGGTCCCCAATTTCCCCGAGGGATCGCCGTTCGAGAAATTCTTCCACGATTTCATGAACCGGCAGACCG
GGCCCGAGGCCGCGCCGCGCAAGATGCAGGCGCTGGGGTCGGGCTTCATCATCGACCCGTCGGGGATCGTCGTCACCAAC
AACCACGTCGTCCGCCACGCGGACCAGATCACGGTGACGCTGCAGGACAATACGGTGCTCAAGGCGCATTTGCTGGGCCA
TGACGACCGGACCGACCTCGCGGTGCTGAAGGTCGATGCGCCCCATCCGCTGCCCGCCGTGCCCTTCGGCGACAGCGACC
ATGCGCGTGTGGGCGACTGGGTGCTGGCGATCGGCAATCCGTTCGGCCTGTCGGGCACGGTGACGGCCGGCATCATCTCG
TCCCGCGGCCGCAATATCGAACAGGGTCCGTACGACGATTTCATCCAGACCGACGCCCCGATCAACAAGGGCAATTCCGG
CGGTCCGCTGTTCGACATGCAGGGGCAGGTGATCGGCATCAACACTGCGATCTATTCGCCCTCCGGCGGGTCGATCGGCA
TCGGCTTCTCCATTCCCTCGGCCGAGGCGCGGGGCATCATCGACCAGCTCCGCCGCACCGGCAAGGTGTCGCGTGGCTGG
ATCGGCGTGCGGATCCAGGACGTGACCCAGGACATCGCCGACGGGCTGGGCCTTAAGGTCGCGCGCGGCGCCCTGATCGC
GGGGATCGAGCCCAAGGGCCCGGCGGCGGCGGCGAAGCTGCAGACCGGCGACGTGATCCAGACCCTGGACGGCAAGGAGA
TCGACGGCCGCGCCCTGCCGCGCCTGATGGCCGACGAATCCCCCGGCCGGGTGGTCAGCCTGGGGGTGTGGCGCCATGGT
CATGTCCTGACTGTTCCCGTCACGGTCGGCGCCCTGCCCGAGGAAGCGGCCGAGGCCCCGGCGCCCAAGCCCGCCGCCAC
GGCCCAGGGCAACGTTCAGTTGCAGGGCATGGGCTTCACCGTGGGGGCGATCGACGACGTCGCCCGGCAGAAATACAGCC
TGGCCGAGGGGCAGAAGGGCGTGGTCGTCACCGCGGTGGCCGCCGACGGCCCGGCCGCCGATCGCGGCCTGCGCCCCGGC
GACGTGATCACCGAGGTCCAGCAGTCCGAGGTCGCGTCCCCCGCCGACCTGCGCCGCCTGGTCGAGGCGGCGCGCGCGCA
GCATCGGCGTTCGGTCCTGTTCCTGGTGCAGAACGGCGACGGGCTGCGCTGGGTGCCGCTCCCGCTGGTCGGAGGGGACG
GGAAATAG

Upstream 100 bases:

>100_bases
GTCCGGGCATATTTATCACACTGATCGCTTCAAGCCGGGGCGATCCGTGTCTAGGATGCAGCCTCCGCGACGTCCTCGTT
TTCTGGAAGCTGCCTGCCCG

Downstream 100 bases:

>100_bases
CGTGACGGCGCGGGACCCCGGGACAACCGGACCGGCCGGAACCGGCGTCGCCGCCGGCCGCTGGGCCGCGATCCGGCGGG
CGCTGGAACCGCGTGGCGCC

Product: serine protease do-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MPLTVPVFFRPCAAVGLAAALSLIAGGGLRAEPAVVPHPVAPAAPAAPAVPPVTVPPVHLPAPGRGAPDSFADLAARLLP
AVVNVSTTETVKPGDQDGDSDGDGGGEDTPQVPNFPEGSPFEKFFHDFMNRQTGPEAAPRKMQALGSGFIIDPSGIVVTN
NHVVRHADQITVTLQDNTVLKAHLLGHDDRTDLAVLKVDAPHPLPAVPFGDSDHARVGDWVLAIGNPFGLSGTVTAGIIS
SRGRNIEQGPYDDFIQTDAPINKGNSGGPLFDMQGQVIGINTAIYSPSGGSIGIGFSIPSAEARGIIDQLRRTGKVSRGW
IGVRIQDVTQDIADGLGLKVARGALIAGIEPKGPAAAAKLQTGDVIQTLDGKEIDGRALPRLMADESPGRVVSLGVWRHG
HVLTVPVTVGALPEEAAEAPAPKPAATAQGNVQLQGMGFTVGAIDDVARQKYSLAEGQKGVVVTAVAADGPAADRGLRPG
DVITEVQQSEVASPADLRRLVEAARAQHRRSVLFLVQNGDGLRWVPLPLVGGDGK

Sequences:

>Translated_535_residues
MPLTVPVFFRPCAAVGLAAALSLIAGGGLRAEPAVVPHPVAPAAPAAPAVPPVTVPPVHLPAPGRGAPDSFADLAARLLP
AVVNVSTTETVKPGDQDGDSDGDGGGEDTPQVPNFPEGSPFEKFFHDFMNRQTGPEAAPRKMQALGSGFIIDPSGIVVTN
NHVVRHADQITVTLQDNTVLKAHLLGHDDRTDLAVLKVDAPHPLPAVPFGDSDHARVGDWVLAIGNPFGLSGTVTAGIIS
SRGRNIEQGPYDDFIQTDAPINKGNSGGPLFDMQGQVIGINTAIYSPSGGSIGIGFSIPSAEARGIIDQLRRTGKVSRGW
IGVRIQDVTQDIADGLGLKVARGALIAGIEPKGPAAAAKLQTGDVIQTLDGKEIDGRALPRLMADESPGRVVSLGVWRHG
HVLTVPVTVGALPEEAAEAPAPKPAATAQGNVQLQGMGFTVGAIDDVARQKYSLAEGQKGVVVTAVAADGPAADRGLRPG
DVITEVQQSEVASPADLRRLVEAARAQHRRSVLFLVQNGDGLRWVPLPLVGGDGK
>Mature_534_residues
PLTVPVFFRPCAAVGLAAALSLIAGGGLRAEPAVVPHPVAPAAPAAPAVPPVTVPPVHLPAPGRGAPDSFADLAARLLPA
VVNVSTTETVKPGDQDGDSDGDGGGEDTPQVPNFPEGSPFEKFFHDFMNRQTGPEAAPRKMQALGSGFIIDPSGIVVTNN
HVVRHADQITVTLQDNTVLKAHLLGHDDRTDLAVLKVDAPHPLPAVPFGDSDHARVGDWVLAIGNPFGLSGTVTAGIISS
RGRNIEQGPYDDFIQTDAPINKGNSGGPLFDMQGQVIGINTAIYSPSGGSIGIGFSIPSAEARGIIDQLRRTGKVSRGWI
GVRIQDVTQDIADGLGLKVARGALIAGIEPKGPAAAAKLQTGDVIQTLDGKEIDGRALPRLMADESPGRVVSLGVWRHGH
VLTVPVTVGALPEEAAEAPAPKPAATAQGNVQLQGMGFTVGAIDDVARQKYSLAEGQKGVVVTAVAADGPAADRGLRPGD
VITEVQQSEVASPADLRRLVEAARAQHRRSVLFLVQNGDGLRWVPLPLVGGDGK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=246, Percent_Identity=36.9918699186992, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=34.7328244274809, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24308541, Length=244, Percent_Identity=34.4262295081967, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7019477, Length=243, Percent_Identity=35.8024691358025, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1789629, Length=439, Percent_Identity=38.0410022779043, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1786356, Length=476, Percent_Identity=34.8739495798319, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1789630, Length=279, Percent_Identity=42.2939068100358, Blast_Score=190, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24646839, Length=285, Percent_Identity=31.9298245614035, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 55260; Mature: 55129

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTVPVFFRPCAAVGLAAALSLIAGGGLRAEPAVVPHPVAPAAPAAPAVPPVTVPPVHL
CCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
PAPGRGAPDSFADLAARLLPAVVNVSTTETVKPGDQDGDSDGDGGGEDTPQVPNFPEGSP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
FEKFFHDFMNRQTGPEAAPRKMQALGSGFIIDPSGIVVTNNHVVRHADQITVTLQDNTVL
HHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCEEEECCCEEEECCEEEEEEECCEEE
KAHLLGHDDRTDLAVLKVDAPHPLPAVPFGDSDHARVGDWVLAIGNPFGLSGTVTAGIIS
EEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHH
SRGRNIEQGPYDDFIQTDAPINKGNSGGPLFDMQGQVIGINTAIYSPSGGSIGIGFSIPS
HCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEECCCCEEEEEEEEECCCCCCEEEEEECCC
AEARGIIDQLRRTGKVSRGWIGVRIQDVTQDIADGLGLKVARGALIAGIEPKGPAAAAKL
HHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCEEECCEEEECCCCCCCCHHEEC
QTGDVIQTLDGKEIDGRALPRLMADESPGRVVSLGVWRHGHVLTVPVTVGALPEEAAEAP
CCCCEEECCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHCC
APKPAATAQGNVQLQGMGFTVGAIDDVARQKYSLAEGQKGVVVTAVAADGPAADRGLRPG
CCCCCCCCCCCEEEEECCEEECHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHCCCCCCC
DVITEVQQSEVASPADLRRLVEAARAQHRRSVLFLVQNGDGLRWVPLPLVGGDGK
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEEECCCCC
>Mature Secondary Structure 
PLTVPVFFRPCAAVGLAAALSLIAGGGLRAEPAVVPHPVAPAAPAAPAVPPVTVPPVHL
CEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
PAPGRGAPDSFADLAARLLPAVVNVSTTETVKPGDQDGDSDGDGGGEDTPQVPNFPEGSP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
FEKFFHDFMNRQTGPEAAPRKMQALGSGFIIDPSGIVVTNNHVVRHADQITVTLQDNTVL
HHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCEEEECCCEEEECCEEEEEEECCEEE
KAHLLGHDDRTDLAVLKVDAPHPLPAVPFGDSDHARVGDWVLAIGNPFGLSGTVTAGIIS
EEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHH
SRGRNIEQGPYDDFIQTDAPINKGNSGGPLFDMQGQVIGINTAIYSPSGGSIGIGFSIPS
HCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEECCCCEEEEEEEEECCCCCCEEEEEECCC
AEARGIIDQLRRTGKVSRGWIGVRIQDVTQDIADGLGLKVARGALIAGIEPKGPAAAAKL
HHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCEEECCEEEECCCCCCCCHHEEC
QTGDVIQTLDGKEIDGRALPRLMADESPGRVVSLGVWRHGHVLTVPVTVGALPEEAAEAP
CCCCEEECCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHCC
APKPAATAQGNVQLQGMGFTVGAIDDVARQKYSLAEGQKGVVVTAVAADGPAADRGLRPG
CCCCCCCCCCCEEEEECCEEECHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHCCCCCCC
DVITEVQQSEVASPADLRRLVEAARAQHRRSVLFLVQNGDGLRWVPLPLVGGDGK
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]