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The map label for this gene is cobP [H]

Identifier: 162146668

GI number: 162146668

Start: 863550

End: 864152

Strand: Direct

Name: cobP [H]

Synonym: GDI_0846

Alternate gene names: 162146668

Gene position: 863550-864152 (Clockwise)

Preceding gene: 162146665

Following gene: 162146670

Centisome position: 21.89

GC content: 71.97

Gene sequence:

>603_bases
GTGGCGTTATGCGCCGCGATGCAAGACAGCGTGGTGGGGGACAACGGGGGGCGCGCGATGGAACCGGCGGGATGCGGGGC
GGACAGACACGACGGAGCGGACTGGACCCTGGTTCTGGGCGGCGTCCGGTCGGGCAAGAGCCGCCATGCCGAGGCCCTGG
TCACGGCGTGCCCGGGACCCTGGACCTATATCGCGACCGGCCGGGCCTGGGATGACGAGATGCGCCGGCGGATCGCCCAT
CACCGGGCCGCGCGCATCCCCGGCTGGCACACGGTCGAGGAACCGCTGGACCTTTCCGCCGCCCTGGACTGGGCCGGCGG
GATGCCGGTCCTGGTGGATTGCCTGACGCTGTGGCTGACCAACCTGATCCTGGACGACCGCGATGTCGCGGCCGCGACGG
AAGGGCTGCTGCAGGCCCTGTGGCGACGTCCGGCGCCGACCGTCCTGGTGGGGAACGAGGTGGGGCTGGGCATCGTGCCC
GAAACGCCGCTCGGCCGCCGCTTCCGTGACGAGGCCGGGTGGCTGCACCAGGCGATCGCCCGCGATGCGCGGCGAGTCAT
GTTCGTGGTCGCGGGCCTGCCCCTGACGGTAAAGGACGGATAA

Upstream 100 bases:

>100_bases
CCTCGTCCGGCGGCGGCAGGTCCGCGCAGGCCGCGCGCAGGGCATCCGGCGTGGGAAAGGGCAGGGAGGTGCGGCGCGGG
GCTGGCATGGCGCTTTTTGT

Downstream 100 bases:

>100_bases
GAGGCAGGACTTTTGAAACAGCCTCCGGTGCTACGCCGCGCGGGCCGACCGGGCCCAGGGCGCGGTCGCGAAACGGCTTG
CCAGATACTCCAGAAGTACC

Product: bifunctional adenosylcobalamin biosynthesis protein cobP

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MALCAAMQDSVVGDNGGRAMEPAGCGADRHDGADWTLVLGGVRSGKSRHAEALVTACPGPWTYIATGRAWDDEMRRRIAH
HRAARIPGWHTVEEPLDLSAALDWAGGMPVLVDCLTLWLTNLILDDRDVAAATEGLLQALWRRPAPTVLVGNEVGLGIVP
ETPLGRRFRDEAGWLHQAIARDARRVMFVVAGLPLTVKDG

Sequences:

>Translated_200_residues
MALCAAMQDSVVGDNGGRAMEPAGCGADRHDGADWTLVLGGVRSGKSRHAEALVTACPGPWTYIATGRAWDDEMRRRIAH
HRAARIPGWHTVEEPLDLSAALDWAGGMPVLVDCLTLWLTNLILDDRDVAAATEGLLQALWRRPAPTVLVGNEVGLGIVP
ETPLGRRFRDEAGWLHQAIARDARRVMFVVAGLPLTVKDG
>Mature_199_residues
ALCAAMQDSVVGDNGGRAMEPAGCGADRHDGADWTLVLGGVRSGKSRHAEALVTACPGPWTYIATGRAWDDEMRRRIAHH
RAARIPGWHTVEEPLDLSAALDWAGGMPVLVDCLTLWLTNLILDDRDVAAATEGLLQALWRRPAPTVLVGNEVGLGIVPE
TPLGRRFRDEAGWLHQAIARDARRVMFVVAGLPLTVKDG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=179, Percent_Identity=44.1340782122905, Blast_Score=123, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21570; Mature: 21439

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALCAAMQDSVVGDNGGRAMEPAGCGADRHDGADWTLVLGGVRSGKSRHAEALVTACPGP
CCCHHHHHHCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHEEECCCC
WTYIATGRAWDDEMRRRIAHHRAARIPGWHTVEEPLDLSAALDWAGGMPVLVDCLTLWLT
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
NLILDDRDVAAATEGLLQALWRRPAPTVLVGNEVGLGIVPETPLGRRFRDEAGWLHQAIA
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RDARRVMFVVAGLPLTVKDG
HHHHHHHHHEECCCEEEECC
>Mature Secondary Structure 
ALCAAMQDSVVGDNGGRAMEPAGCGADRHDGADWTLVLGGVRSGKSRHAEALVTACPGP
CCHHHHHHCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHEEECCCC
WTYIATGRAWDDEMRRRIAHHRAARIPGWHTVEEPLDLSAALDWAGGMPVLVDCLTLWLT
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
NLILDDRDVAAATEGLLQALWRRPAPTVLVGNEVGLGIVPETPLGRRFRDEAGWLHQAIA
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RDARRVMFVVAGLPLTVKDG
HHHHHHHHHEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]