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The map label for this gene is dinB [H]

Identifier: 162146654

GI number: 162146654

Start: 850579

End: 851724

Strand: Direct

Name: dinB [H]

Synonym: GDI_0832

Alternate gene names: 162146654

Gene position: 850579-851724 (Clockwise)

Preceding gene: 162146653

Following gene: 162146655

Centisome position: 21.57

GC content: 68.24

Gene sequence:

>1146_bases
GTGTGCGGGCAGCAGGGCATGTCGCCACAGGATACCGATCCCGACCCCGCTTCCTTACGCCGCATCATCCATGTCGACAT
GGATGCCTTCTATGCCTCCGTCGAACAACGCGATGATCCCGCCCTGCGCGGCCGGCCGCTGGCCGTCGGCGGCAGCAGGC
AGCGCGGCGTCGTCGCCGCGGCCAGTTACGAGGCCCGGCGCTATGGCGTACGCTCCGCCATGCCGTCGGTCACGGCGCGG
CGCAAATGTCCCGACCTGATCTTCGTTCCGCCGCGCTTCGACGTCTATCGGGCGGTTTCGGCGCAGATCCATGCCATCTT
CGCGCGCTATACAGGGCTGATTCAGCCGCTGTCGCTGGATGAAGCCTATCTGGACGTGACCGATCCATTGATCGACCGTC
CCTCCGCCACCGCGATCGCGCAGGATATCCGGGCGGCGATCCGCGCCGAAACGGGCCTGACCGCGTCGGCCGGGGTGTCG
TACAACAAATTCCTGGCCAAGCTGGCCTCGGACTATCGCAAGCCTGACGGGCTGTATGTGATTACACCCCGCATGGGCCC
GCGTTTCGTCGAATCCCTGCCGGTCGAGGCGTTTCACGGGATCGGCCCGGCAACGGCCGCGCGCATGCGCGCGATGGGCA
TCCGCACCGGCCTGGACCTGCGCGCCCACGACATGGACAGCCTGGCCCGGCATTTCGGCAAGGCGGCCGCCTTTTATTAC
GGCATCGCCCGGGGACGGGACGACCGGCCGGTCGAAGCCGACCGCCGCCGAAAATCCGTGGGCACGGAACGCACCTTCGA
ACATGACATCCATGACTGGGCCGAGGCCCTGTCGGCGCTGGACGGCATGGTCGACCGGGTCTGGGGCGAGTGCCGCAAGC
GGGGGCTGGTCGCGCGCACGGTGACGGTGAAGGTCAAATATGCCGATTTCCAGCAGACCGGCCGCGCCCGCTCGCTGCCC
CAGCCGCTGGCCGCGCACGCCGTCTTTCGCCAGGTCGCATGCGACCTGCTGCGGCCGTTCTTTCCGCCAGAACGGGGCAT
CCGCCTGCTGGGGGTGACGCTGTCGAATCTCGACCTCACCGGCGGTGCCAGCCCGCAACTGGCCCTGGCCCTGGATGATC
CCGGGAGTGTTCAGGCCGGGCCGTGA

Upstream 100 bases:

>100_bases
CTGGTGGCGGCAGTGATCTTCTTCTTCAAGAAGAAGTCCTGCTGCAAGGCCGGCGCCTGATCGTATCGCCCCGGGGTCAT
GCTCCGGGGCGGACCTTTTC

Downstream 100 bases:

>100_bases
CCGGAATCGGGCCGGAATGCATCCAAAACGAATATCGTGCGTTTGTGGTGCGTTCGTATCATCGTCGTGCCCACTGACAG
AGTCGCGTCCGGCCGGCCGT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MCGQQGMSPQDTDPDPASLRRIIHVDMDAFYASVEQRDDPALRGRPLAVGGSRQRGVVAAASYEARRYGVRSAMPSVTAR
RKCPDLIFVPPRFDVYRAVSAQIHAIFARYTGLIQPLSLDEAYLDVTDPLIDRPSATAIAQDIRAAIRAETGLTASAGVS
YNKFLAKLASDYRKPDGLYVITPRMGPRFVESLPVEAFHGIGPATAARMRAMGIRTGLDLRAHDMDSLARHFGKAAAFYY
GIARGRDDRPVEADRRRKSVGTERTFEHDIHDWAEALSALDGMVDRVWGECRKRGLVARTVTVKVKYADFQQTGRARSLP
QPLAAHAVFRQVACDLLRPFFPPERGIRLLGVTLSNLDLTGGASPQLALALDDPGSVQAGP

Sequences:

>Translated_381_residues
MCGQQGMSPQDTDPDPASLRRIIHVDMDAFYASVEQRDDPALRGRPLAVGGSRQRGVVAAASYEARRYGVRSAMPSVTAR
RKCPDLIFVPPRFDVYRAVSAQIHAIFARYTGLIQPLSLDEAYLDVTDPLIDRPSATAIAQDIRAAIRAETGLTASAGVS
YNKFLAKLASDYRKPDGLYVITPRMGPRFVESLPVEAFHGIGPATAARMRAMGIRTGLDLRAHDMDSLARHFGKAAAFYY
GIARGRDDRPVEADRRRKSVGTERTFEHDIHDWAEALSALDGMVDRVWGECRKRGLVARTVTVKVKYADFQQTGRARSLP
QPLAAHAVFRQVACDLLRPFFPPERGIRLLGVTLSNLDLTGGASPQLALALDDPGSVQAGP
>Mature_381_residues
MCGQQGMSPQDTDPDPASLRRIIHVDMDAFYASVEQRDDPALRGRPLAVGGSRQRGVVAAASYEARRYGVRSAMPSVTAR
RKCPDLIFVPPRFDVYRAVSAQIHAIFARYTGLIQPLSLDEAYLDVTDPLIDRPSATAIAQDIRAAIRAETGLTASAGVS
YNKFLAKLASDYRKPDGLYVITPRMGPRFVESLPVEAFHGIGPATAARMRAMGIRTGLDLRAHDMDSLARHFGKAAAFYY
GIARGRDDRPVEADRRRKSVGTERTFEHDIHDWAEALSALDGMVDRVWGECRKRGLVARTVTVKVKYADFQQTGRARSLP
QPLAAHAVFRQVACDLLRPFFPPERGIRLLGVTLSNLDLTGGASPQLALALDDPGSVQAGP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=28.4023668639053, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=28.3185840707965, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI154350220, Length=362, Percent_Identity=27.3480662983425, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI7705344, Length=114, Percent_Identity=50.8771929824561, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI5729982, Length=123, Percent_Identity=38.2113821138211, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786425, Length=354, Percent_Identity=46.045197740113, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1787432, Length=218, Percent_Identity=30.2752293577982, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=401, Percent_Identity=31.4214463840399, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=30.5019305019305, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=225, Percent_Identity=32.4444444444444, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=40.3225806451613, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=249, Percent_Identity=26.9076305220884, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355641, Length=386, Percent_Identity=27.979274611399, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24644984, Length=386, Percent_Identity=27.979274611399, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19923006, Length=345, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=34.9593495934959, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41697; Mature: 41697

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGQQGMSPQDTDPDPASLRRIIHVDMDAFYASVEQRDDPALRGRPLAVGGSRQRGVVAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEE
ASYEARRYGVRSAMPSVTARRKCPDLIFVPPRFDVYRAVSAQIHAIFARYTGLIQPLSLD
ECHHHHHHHHHHHCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EAYLDVTDPLIDRPSATAIAQDIRAAIRAETGLTASAGVSYNKFLAKLASDYRKPDGLYV
HHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
ITPRMGPRFVESLPVEAFHGIGPATAARMRAMGIRTGLDLRAHDMDSLARHFGKAAAFYY
ECCCCCHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
GIARGRDDRPVEADRRRKSVGTERTFEHDIHDWAEALSALDGMVDRVWGECRKRGLVART
HHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VTVKVKYADFQQTGRARSLPQPLAAHAVFRQVACDLLRPFFPPERGIRLLGVTLSNLDLT
EEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECEEEC
GGASPQLALALDDPGSVQAGP
CCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MCGQQGMSPQDTDPDPASLRRIIHVDMDAFYASVEQRDDPALRGRPLAVGGSRQRGVVAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEE
ASYEARRYGVRSAMPSVTARRKCPDLIFVPPRFDVYRAVSAQIHAIFARYTGLIQPLSLD
ECHHHHHHHHHHHCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EAYLDVTDPLIDRPSATAIAQDIRAAIRAETGLTASAGVSYNKFLAKLASDYRKPDGLYV
HHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
ITPRMGPRFVESLPVEAFHGIGPATAARMRAMGIRTGLDLRAHDMDSLARHFGKAAAFYY
ECCCCCHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
GIARGRDDRPVEADRRRKSVGTERTFEHDIHDWAEALSALDGMVDRVWGECRKRGLVART
HHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VTVKVKYADFQQTGRARSLPQPLAAHAVFRQVACDLLRPFFPPERGIRLLGVTLSNLDLT
EEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECEEEC
GGASPQLALALDDPGSVQAGP
CCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA