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The map label for this gene is atpA

Identifier: 162146518

GI number: 162146518

Start: 705042

End: 706583

Strand: Direct

Name: atpA

Synonym: GDI_0694

Alternate gene names: 162146518

Gene position: 705042-706583 (Clockwise)

Preceding gene: 162146517

Following gene: 162146519

Centisome position: 17.88

GC content: 66.02

Gene sequence:

>1542_bases
GTGATGGAAATCCGCCCCGCCGAGATTTCGGATATCCTCAAGCAGCAGATCGCCACGTTCGACACGCCGGTTGATATTGC
CGAGACGGGCACGATCCTGTCGGTCGGCGACGGCATCGCCCGCGTCTACGGCCTGCAGAACGTGCAGGCCGGCGAAATGG
TCGAATTCCCGGGATCGGGCCAGCGCGGCATGGCGCTGAACCTGGAAAACGACAATGTCGGCGTCGTGATCTTCGGCGAT
GACGCCGACATGCGCGAAGGCGACACCGTCTCGCGCACCGGCGCGGTGGTCGAGGTCCCGACCGGCAAGGCCCTGCTGGG
CCGCGTGGTCGACGGCCTGGGCAACCCGATCGACGGCAAGGGACCGCTGGTCGGCGACGTCGTCATGAAGCGCGCCGACG
TCAAGGCGCCCGGCATCATGCCGCGCCAGTCGGTCGGCGAGCCGATGCAGACCGGAATCAAGGCGATCGACGCCCTGGTG
CCCATCGGACGCGGCCAGCGCGAACTGATCATCGGCGACCGCCAGACCGGCAAGACGGCCATCCTGATCGACACCATCGT
CGCGCAGAAGTCGGTCAACGCCCTGGGCGACGACAAGAAGTCGCTGTACTGCATCTATGTCGCCATCGGCCAGAAGCGCT
CGACGGTGGCCCAGCTGGTCCGCACGCTGGAGGAAACCGGCGCGATGGAATATTCCATCGTCGTCGCCGCCACCGCGTCC
GACCCGGCGCCGATGCAGTACCTGGCCCCGTACGCCGCCTGCGCCATGGGCGAATATTTCCGCGACAACGGCATGCATGC
CCTGATCGTGTATGACGACCTGTCCAAGCAGGCCGTGGCCTATCGCCAGATGTCGCTGCTGCTGCGCCGCCCGCCGGGCC
GCGAGGCCTATCCGGGCGATGTGTTTTACCTGCATTCCCGCCTGCTGGAACGCGCGGCGAAGATGTCGGATGAATACGGC
GCGGGTTCGCTGACGGCGCTGCCGGTCATCGAAACCCAGGCCGGCGACGTTTCGGCCTATATCCCGACCAACGTGATCTC
GATCACCGACGGCCAGGTGTTCCTGGAAACCGACCTGTTCTATCGCGGCATCCGCCCGGCGGTGAATGTCGGCGGTTCGG
TGTCGCGCGTCGGCTCGGCCGCGCAGATCAAGGCGATGAAGCAGGTCGCCGGCAAGATCAAGCTGGAACTGGCGCAGTAC
CGCGAAATGGCGGCGTTCTCGCAGTTCGCGTCCGACCTCGATCCCGCCACGCAGAAGCAGCTTGCGCGCGGCGCGCGGCT
GGTCGAACTGCTGAAGCAGCCCGAAACCTCGCCCCTCGCGGTCGAGGAGCAGGTGTGCGTCCTGTTCGCGGGCACTCGCG
GCTTCATTGACGCGGTGCCGGTGGACAAGGTGAGCAGCTACGAGCGCCAGCTGCTGGCCGAACTGCACACCGGCGGCAAG
GAAATCCTGGAATCGATCCGCACTGAGCGGCAGATCACCAAGGATAATGAAACGCGCCTGACCGACTTCCTGACGAGCTT
CGGCCGTCAGTTCGCGGGCTGA

Upstream 100 bases:

>100_bases
CGCTGCTGGGCGGCCTGGTCGTGCGCGTCGGCGCGCGCCTGTACGACACCAGCCTCCGGTCCCGCCTGACCCGCCTGCAC
CACGCCATGAAGGGAGCCGC

Downstream 100 bases:

>100_bases
AGGCGGACAGGCACCCATGGCATCCCTCAAGGACCTTCGCGCGCGGATCGGCAGCGTCAAATCGACGAGGAAGATCACCA
GCGCCATGAAGATGGTGGCG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MMEIRPAEISDILKQQIATFDTPVDIAETGTILSVGDGIARVYGLQNVQAGEMVEFPGSGQRGMALNLENDNVGVVIFGD
DADMREGDTVSRTGAVVEVPTGKALLGRVVDGLGNPIDGKGPLVGDVVMKRADVKAPGIMPRQSVGEPMQTGIKAIDALV
PIGRGQRELIIGDRQTGKTAILIDTIVAQKSVNALGDDKKSLYCIYVAIGQKRSTVAQLVRTLEETGAMEYSIVVAATAS
DPAPMQYLAPYAACAMGEYFRDNGMHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDEYG
AGSLTALPVIETQAGDVSAYIPTNVISITDGQVFLETDLFYRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQY
REMAAFSQFASDLDPATQKQLARGARLVELLKQPETSPLAVEEQVCVLFAGTRGFIDAVPVDKVSSYERQLLAELHTGGK
EILESIRTERQITKDNETRLTDFLTSFGRQFAG

Sequences:

>Translated_513_residues
MMEIRPAEISDILKQQIATFDTPVDIAETGTILSVGDGIARVYGLQNVQAGEMVEFPGSGQRGMALNLENDNVGVVIFGD
DADMREGDTVSRTGAVVEVPTGKALLGRVVDGLGNPIDGKGPLVGDVVMKRADVKAPGIMPRQSVGEPMQTGIKAIDALV
PIGRGQRELIIGDRQTGKTAILIDTIVAQKSVNALGDDKKSLYCIYVAIGQKRSTVAQLVRTLEETGAMEYSIVVAATAS
DPAPMQYLAPYAACAMGEYFRDNGMHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDEYG
AGSLTALPVIETQAGDVSAYIPTNVISITDGQVFLETDLFYRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQY
REMAAFSQFASDLDPATQKQLARGARLVELLKQPETSPLAVEEQVCVLFAGTRGFIDAVPVDKVSSYERQLLAELHTGGK
EILESIRTERQITKDNETRLTDFLTSFGRQFAG
>Mature_513_residues
MMEIRPAEISDILKQQIATFDTPVDIAETGTILSVGDGIARVYGLQNVQAGEMVEFPGSGQRGMALNLENDNVGVVIFGD
DADMREGDTVSRTGAVVEVPTGKALLGRVVDGLGNPIDGKGPLVGDVVMKRADVKAPGIMPRQSVGEPMQTGIKAIDALV
PIGRGQRELIIGDRQTGKTAILIDTIVAQKSVNALGDDKKSLYCIYVAIGQKRSTVAQLVRTLEETGAMEYSIVVAATAS
DPAPMQYLAPYAACAMGEYFRDNGMHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDEYG
AGSLTALPVIETQAGDVSAYIPTNVISITDGQVFLETDLFYRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQY
REMAAFSQFASDLDPATQKQLARGARLVELLKQPETSPLAVEEQVCVLFAGTRGFIDAVPVDKVSSYERQLLAELHTGGK
EILESIRTERQITKDNETRLTDFLTSFGRQFAG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=501, Percent_Identity=69.4610778443114, Blast_Score=716, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=501, Percent_Identity=69.4610778443114, Blast_Score=716, Evalue=0.0,
Organism=Homo sapiens, GI19913426, Length=363, Percent_Identity=28.099173553719, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI19913428, Length=335, Percent_Identity=27.7611940298507, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI32189394, Length=397, Percent_Identity=23.6775818639798, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=28.6290322580645, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790172, Length=517, Percent_Identity=57.0599613152805, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1788251, Length=346, Percent_Identity=28.0346820809249, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790170, Length=341, Percent_Identity=25.5131964809384, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=505, Percent_Identity=67.7227722772277, Blast_Score=710, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=505, Percent_Identity=67.7227722772277, Blast_Score=708, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=505, Percent_Identity=63.1683168316832, Blast_Score=647, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=331, Percent_Identity=28.3987915407855, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=299, Percent_Identity=28.7625418060201, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=60, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=68, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25144756, Length=315, Percent_Identity=24.7619047619048, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=26.3779527559055, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=64.4970414201183, Blast_Score=671, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=332, Percent_Identity=28.9156626506024, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=380, Percent_Identity=24.2105263157895, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24658560, Length=509, Percent_Identity=67.3870333988212, Blast_Score=696, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=333, Percent_Identity=27.6276276276276, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24646341, Length=333, Percent_Identity=27.6276276276276, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17136796, Length=333, Percent_Identity=27.6276276276276, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI28574560, Length=419, Percent_Identity=25.0596658711217, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24638766, Length=389, Percent_Identity=24.4215938303342, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129479, Length=246, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583992, Length=248, Percent_Identity=27.0161290322581, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_GLUDA (A9H9A4)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001600977.1
- RefSeq:   YP_002275712.1
- ProteinModelPortal:   A9H9A4
- SMR:   A9H9A4
- GeneID:   5790136
- GeneID:   6974720
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_1315
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55281; Mature: 55281

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEIRPAEISDILKQQIATFDTPVDIAETGTILSVGDGIARVYGLQNVQAGEMVEFPGSG
CCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCCCCCCCCEEECCCCC
QRGMALNLENDNVGVVIFGDDADMREGDTVSRTGAVVEVPTGKALLGRVVDGLGNPIDGK
CCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCC
GPLVGDVVMKRADVKAPGIMPRQSVGEPMQTGIKAIDALVPIGRGQRELIIGDRQTGKTA
CCCHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEE
ILIDTIVAQKSVNALGDDKKSLYCIYVAIGQKRSTVAQLVRTLEETGAMEYSIVVAATAS
EEEHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECC
DPAPMQYLAPYAACAMGEYFRDNGMHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGD
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERAAKMSDEYGAGSLTALPVIETQAGDVSAYIPTNVISITDGQVFLETDLF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHH
YRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQYREMAAFSQFASDLDPATQKQ
HHCCCHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LARGARLVELLKQPETSPLAVEEQVCVLFAGTRGFIDAVPVDKVSSYERQLLAELHTGGK
HHHHHHHHHHHHCCCCCCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
EILESIRTERQITKDNETRLTDFLTSFGRQFAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMEIRPAEISDILKQQIATFDTPVDIAETGTILSVGDGIARVYGLQNVQAGEMVEFPGSG
CCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCCCCCCCCEEECCCCC
QRGMALNLENDNVGVVIFGDDADMREGDTVSRTGAVVEVPTGKALLGRVVDGLGNPIDGK
CCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCC
GPLVGDVVMKRADVKAPGIMPRQSVGEPMQTGIKAIDALVPIGRGQRELIIGDRQTGKTA
CCCHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEE
ILIDTIVAQKSVNALGDDKKSLYCIYVAIGQKRSTVAQLVRTLEETGAMEYSIVVAATAS
EEEHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECC
DPAPMQYLAPYAACAMGEYFRDNGMHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGD
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERAAKMSDEYGAGSLTALPVIETQAGDVSAYIPTNVISITDGQVFLETDLF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHH
YRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQYREMAAFSQFASDLDPATQKQ
HHCCCHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LARGARLVELLKQPETSPLAVEEQVCVLFAGTRGFIDAVPVDKVSSYERQLLAELHTGGK
HHHHHHHHHHHHCCCCCCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHH
EILESIRTERQITKDNETRLTDFLTSFGRQFAG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA