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The map label for this gene is csd [H]

Identifier: 162146439

GI number: 162146439

Start: 623839

End: 625314

Strand: Reverse

Name: csd [H]

Synonym: GDI_0614

Alternate gene names: 162146439

Gene position: 625314-623839 (Counterclockwise)

Preceding gene: 162146445

Following gene: 162146434

Centisome position: 15.85

GC content: 69.17

Gene sequence:

>1476_bases
ATGCAGGACGACCAGCCCCCTTTTGCGGATTTCATCGCATCCTTGCGAGTGGACGACCTGTCCGGATTGCGCGCCGGGCT
GATCGGCGAGGGCGCGCCCGTGCCCGGACCGTTCGGCGTCCATCCGCTGGTCTATGCCGATTATGTGGCATCCGGCCGGG
CGTTGCGGCAGGTCGAGGATTTCGTGATGAACCGGGTCCTGCCCTATTACGCCAACAGCCATACCGAGGCATCGTTCTGC
GGCCGGCATGTCAGCCGGATGCGGCGGGCGGCGCGCGAGGCGATCGCGCAATCATGCCGTGCGGGGGCGGGATTTTCCAC
GATCTTTACCGGGTCGGGCGCGACGGCGGGGCTGAATCGCCTGGTTCACCTGCTGGGCGTGGCCGATGCCGCCCGGGCAG
GCGAGGCCCCGGTGGTGTTCATCGGCCCGTACGAGCATCATTCCAACATCCTGCCCTGGCGCGAGAGCGGTGCCGAGATC
GTCGCCATCGACGAGGCGGAGGGCGGCGGCCCCGACCTGGCGCATCTGGCGGCGGCGCTGCAGGCCGCCGGTCCCGGCCG
GTTGAAGGTGGGGGCCTTCTCGGCGGCGTCCAACGTGACGGGCATCGTCACCGACACCGACGCCGTCACGGCGCTGCTGA
AGGCGCACGGCGCCCGCGCGGTATGGGATTATGCCGGCGGCGGCCCGTACCTGCCGATCGACATGAAGGGGGGCGACATG
AAGGGGGGCACGGCGTGCGAAAAGGATGCCGTCGTGATCTCGCCGCACAAATTCATCGGCGGTCCGGGCGCGTCGGGGGT
CATGATCGTGCGCGACGCGGCGGTGACGCACCACCGCCCGGTCTTCACTGGCGGGGGCACGGTGCGGTTCGTCTCGCCCT
GGGGTCACGATTACGCCGAAAGCATCGCCAGCCGCGAGGAAGCGGGCACGCCCAATGTGGTGGGCGACATTCGCGCGGGG
CTGGCGTTCCTGGTCAAGGCGGCGATCGGACAGGCGCGCATGGATGCGCGCCACGCCGCGCTGTACCGCATGGCCAGGGC
GGTATGGGACCGTAATCCCAATATCGCGATTCTGGGCCTGTCCGGGAAGCATCCACGCGCGGCATCCTGCCTGCCGATCT
TCTCGTTCCAGGTCCGCGACGCCCGGCGGGGCGGAATGATCCACCAGCAATTGTTCACCCGCATGCTGTCCGACCGCTAC
GGCATCCAGGCCCGTGGGGGATGCGCCTGCGCCGGACCGTACGCCCACCGGTTGCTGGGCATCGACCGGGACGCCTCGCA
GGCGCTGCGCGCCGCGATCCTGGAGGGGGACGAAATCAGCAAGCCCGGCTGGACGCGGCTGAATTTCAGCGTGCTGATGG
ATGATGAAAAGGCCGGGCGCATCATCGCGGCGGTGGACGAACTGGCCCGCGCGCCCTATCCGACCGCCGACCATTACACG
GTCGATCCGGCCACCGCCCGATTCCGCGCGGCATGA

Upstream 100 bases:

>100_bases
ATATGACCCGATTCGGCCCATTTCAATGCAGGAAAAGGGGAAGTTCTTTCCCGCCGCGCCGTCTATTTTCATCGCGAACC
CTCTTGAGGCGAACAGTGCG

Downstream 100 bases:

>100_bases
AGGCAGGCAGGGCCCGATGCCCTGCCCCCCCCAATCGATTTTTCCAAGGGGTCAGCCCCTGCGGCGGGCCAAGGGCTGAG
CCCTGGCCCGCCTTTGGTCA

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MQDDQPPFADFIASLRVDDLSGLRAGLIGEGAPVPGPFGVHPLVYADYVASGRALRQVEDFVMNRVLPYYANSHTEASFC
GRHVSRMRRAAREAIAQSCRAGAGFSTIFTGSGATAGLNRLVHLLGVADAARAGEAPVVFIGPYEHHSNILPWRESGAEI
VAIDEAEGGGPDLAHLAAALQAAGPGRLKVGAFSAASNVTGIVTDTDAVTALLKAHGARAVWDYAGGGPYLPIDMKGGDM
KGGTACEKDAVVISPHKFIGGPGASGVMIVRDAAVTHHRPVFTGGGTVRFVSPWGHDYAESIASREEAGTPNVVGDIRAG
LAFLVKAAIGQARMDARHAALYRMARAVWDRNPNIAILGLSGKHPRAASCLPIFSFQVRDARRGGMIHQQLFTRMLSDRY
GIQARGGCACAGPYAHRLLGIDRDASQALRAAILEGDEISKPGWTRLNFSVLMDDEKAGRIIAAVDELARAPYPTADHYT
VDPATARFRAA

Sequences:

>Translated_491_residues
MQDDQPPFADFIASLRVDDLSGLRAGLIGEGAPVPGPFGVHPLVYADYVASGRALRQVEDFVMNRVLPYYANSHTEASFC
GRHVSRMRRAAREAIAQSCRAGAGFSTIFTGSGATAGLNRLVHLLGVADAARAGEAPVVFIGPYEHHSNILPWRESGAEI
VAIDEAEGGGPDLAHLAAALQAAGPGRLKVGAFSAASNVTGIVTDTDAVTALLKAHGARAVWDYAGGGPYLPIDMKGGDM
KGGTACEKDAVVISPHKFIGGPGASGVMIVRDAAVTHHRPVFTGGGTVRFVSPWGHDYAESIASREEAGTPNVVGDIRAG
LAFLVKAAIGQARMDARHAALYRMARAVWDRNPNIAILGLSGKHPRAASCLPIFSFQVRDARRGGMIHQQLFTRMLSDRY
GIQARGGCACAGPYAHRLLGIDRDASQALRAAILEGDEISKPGWTRLNFSVLMDDEKAGRIIAAVDELARAPYPTADHYT
VDPATARFRAA
>Mature_491_residues
MQDDQPPFADFIASLRVDDLSGLRAGLIGEGAPVPGPFGVHPLVYADYVASGRALRQVEDFVMNRVLPYYANSHTEASFC
GRHVSRMRRAAREAIAQSCRAGAGFSTIFTGSGATAGLNRLVHLLGVADAARAGEAPVVFIGPYEHHSNILPWRESGAEI
VAIDEAEGGGPDLAHLAAALQAAGPGRLKVGAFSAASNVTGIVTDTDAVTALLKAHGARAVWDYAGGGPYLPIDMKGGDM
KGGTACEKDAVVISPHKFIGGPGASGVMIVRDAAVTHHRPVFTGGGTVRFVSPWGHDYAESIASREEAGTPNVVGDIRAG
LAFLVKAAIGQARMDARHAALYRMARAVWDRNPNIAILGLSGKHPRAASCLPIFSFQVRDARRGGMIHQQLFTRMLSDRY
GIQARGGCACAGPYAHRLLGIDRDASQALRAAILEGDEISKPGWTRLNFSVLMDDEKAGRIIAAVDELARAPYPTADHYT
VDPATARFRAA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=376, Percent_Identity=25.7978723404255, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789175, Length=353, Percent_Identity=26.628895184136, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193211090, Length=488, Percent_Identity=34.4262295081967, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 51886; Mature: 51886

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDDQPPFADFIASLRVDDLSGLRAGLIGEGAPVPGPFGVHPLVYADYVASGRALRQVED
CCCCCCCHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
FVMNRVLPYYANSHTEASFCGRHVSRMRRAAREAIAQSCRAGAGFSTIFTGSGATAGLNR
HHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
LVHLLGVADAARAGEAPVVFIGPYEHHSNILPWRESGAEIVAIDEAEGGGPDLAHLAAAL
HHHHHHHHHHHHCCCCCEEEECCCHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
QAAGPGRLKVGAFSAASNVTGIVTDTDAVTALLKAHGARAVWDYAGGGPYLPIDMKGGDM
HHCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCC
KGGTACEKDAVVISPHKFIGGPGASGVMIVRDAAVTHHRPVFTGGGTVRFVSPWGHDYAE
CCCCCCCCCCEEECCHHHCCCCCCCCEEEEEECHHHCCCCEEECCCEEEEECCCCCHHHH
SIASREEAGTPNVVGDIRAGLAFLVKAAIGQARMDARHAALYRMARAVWDRNPNIAILGL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
SGKHPRAASCLPIFSFQVRDARRGGMIHQQLFTRMLSDRYGIQARGGCACAGPYAHRLLG
CCCCCCCCCCEEEEEEEECHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHC
IDRDASQALRAAILEGDEISKPGWTRLNFSVLMDDEKAGRIIAAVDELARAPYPTADHYT
CCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEE
VDPATARFRAA
CCCCCCCCCCC
>Mature Secondary Structure
MQDDQPPFADFIASLRVDDLSGLRAGLIGEGAPVPGPFGVHPLVYADYVASGRALRQVED
CCCCCCCHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
FVMNRVLPYYANSHTEASFCGRHVSRMRRAAREAIAQSCRAGAGFSTIFTGSGATAGLNR
HHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
LVHLLGVADAARAGEAPVVFIGPYEHHSNILPWRESGAEIVAIDEAEGGGPDLAHLAAAL
HHHHHHHHHHHHCCCCCEEEECCCHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
QAAGPGRLKVGAFSAASNVTGIVTDTDAVTALLKAHGARAVWDYAGGGPYLPIDMKGGDM
HHCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCC
KGGTACEKDAVVISPHKFIGGPGASGVMIVRDAAVTHHRPVFTGGGTVRFVSPWGHDYAE
CCCCCCCCCCEEECCHHHCCCCCCCCEEEEEECHHHCCCCEEECCCEEEEECCCCCHHHH
SIASREEAGTPNVVGDIRAGLAFLVKAAIGQARMDARHAALYRMARAVWDRNPNIAILGL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
SGKHPRAASCLPIFSFQVRDARRGGMIHQQLFTRMLSDRYGIQARGGCACAGPYAHRLLG
CCCCCCCCCCEEEEEEEECHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHC
IDRDASQALRAAILEGDEISKPGWTRLNFSVLMDDEKAGRIIAAVDELARAPYPTADHYT
CCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEE
VDPATARFRAA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]