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The map label for this gene is cysW [H]

Identifier: 162146385

GI number: 162146385

Start: 566175

End: 566993

Strand: Direct

Name: cysW [H]

Synonym: GDI_0560

Alternate gene names: 162146385

Gene position: 566175-566993 (Clockwise)

Preceding gene: 162146384

Following gene: 162146386

Centisome position: 14.35

GC content: 68.62

Gene sequence:

>819_bases
ATGCCCGGCCGGTCCTCCCGCACGGGCGGCGTCCTGCTGGCGGCTGCGGTGTACGCCGTGGTCCTGCTGGTGCTGGTCCT
TCCGCTGGTGCTGGTCGTCGCCCAGGCGCTGGCCACCGGCTTTGCCCCGGCGTGGCAGAGCCTGCTGGACCCGGACGCCG
TCGCCGCCATTCGTCTGACGCTGGTGGTGACGCTGGCCTCCACCGCCATCAACAGCGTGGGCGGCGTGATGGCGGCATGG
GCGCTGACGAAATACCGCTTTCCCGGCCGTGGGGTCCTGCTGGTCCTGATCGAACTGCCGATCAGCGTGTCGCCGGTGAT
CGCGGGCCTGGTCTGGCTGCTGCTGTTCGGCCGGGGCGGGTGGTGGGGCGCGCTGCTGGCCCGGCATAACATCCAGGTCG
CCTTCGCCACGCCGGGCATTATCCTGGCCACGCTGTTCGTCACCTTTCCCTACGTCGCCCGGACCCTGATGCCGCTGATG
GAACAGCAGGGCCGCGATGCCGAGGAAGCGGCCTTCCTGCTGGGCGCCGGGTTCTGGCAGACGCTGTGGCGCGTCACGAT
CCCGGGCGCGCGCTGGGCCCTGCTGTCGGGCATCCTGCTGACCACCGCGCGCGGCATCGGCGAATTCGGGGCGGTCTCGG
TCGTATCGGGCCACATTCCCGGCCTGACCGAAACCATGCCCCTGCATATCGAGACGCTCTATAACGGCTATCAGACGGTC
GCCGCCTTCGCCATGGCGGCGCTGCTGGCCCTGATTGCGATGACGACCGTCCTGCTGCGGTCGTTCTTCGAGCATGATTT
CAAGAAAGCGTCTTCATGA

Upstream 100 bases:

>100_bases
TCGCGCTGATCCTGCTGGTCAGCGCGCTGCTGTGCCAGACCGGCGTGTCCCGGCTGCGGCGGCGGGCGTCGCGCGGGCTC
GTCGCCCCGGATGCCGCCTG

Downstream 100 bases:

>100_bases
GCGTGCGGCTCGACTCATTGACCCAATACGCCCCCGGCACCTCGCGCAAGCTTCTGGACGACATCTCGCTGACAGTGGAA
GACGGCGCCTTCATTGCCCT

Product: sulfate ABC transporter permease cysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPGRSSRTGGVLLAAAVYAVVLLVLVLPLVLVVAQALATGFAPAWQSLLDPDAVAAIRLTLVVTLASTAINSVGGVMAAW
ALTKYRFPGRGVLLVLIELPISVSPVIAGLVWLLLFGRGGWWGALLARHNIQVAFATPGIILATLFVTFPYVARTLMPLM
EQQGRDAEEAAFLLGAGFWQTLWRVTIPGARWALLSGILLTTARGIGEFGAVSVVSGHIPGLTETMPLHIETLYNGYQTV
AAFAMAALLALIAMTTVLLRSFFEHDFKKASS

Sequences:

>Translated_272_residues
MPGRSSRTGGVLLAAAVYAVVLLVLVLPLVLVVAQALATGFAPAWQSLLDPDAVAAIRLTLVVTLASTAINSVGGVMAAW
ALTKYRFPGRGVLLVLIELPISVSPVIAGLVWLLLFGRGGWWGALLARHNIQVAFATPGIILATLFVTFPYVARTLMPLM
EQQGRDAEEAAFLLGAGFWQTLWRVTIPGARWALLSGILLTTARGIGEFGAVSVVSGHIPGLTETMPLHIETLYNGYQTV
AAFAMAALLALIAMTTVLLRSFFEHDFKKASS
>Mature_271_residues
PGRSSRTGGVLLAAAVYAVVLLVLVLPLVLVVAQALATGFAPAWQSLLDPDAVAAIRLTLVVTLASTAINSVGGVMAAWA
LTKYRFPGRGVLLVLIELPISVSPVIAGLVWLLLFGRGGWWGALLARHNIQVAFATPGIILATLFVTFPYVARTLMPLME
QQGRDAEEAAFLLGAGFWQTLWRVTIPGARWALLSGILLTTARGIGEFGAVSVVSGHIPGLTETMPLHIETLYNGYQTVA
AFAMAALLALIAMTTVLLRSFFEHDFKKASS

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=254, Percent_Identity=48.0314960629921, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI1788764, Length=217, Percent_Identity=37.3271889400922, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786980, Length=213, Percent_Identity=31.924882629108, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28877; Mature: 28745

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGRSSRTGGVLLAAAVYAVVLLVLVLPLVLVVAQALATGFAPAWQSLLDPDAVAAIRLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHH
LVVTLASTAINSVGGVMAAWALTKYRFPGRGVLLVLIELPISVSPVIAGLVWLLLFGRGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
WWGALLARHNIQVAFATPGIILATLFVTFPYVARTLMPLMEQQGRDAEEAAFLLGAGFWQ
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLWRVTIPGARWALLSGILLTTARGIGEFGAVSVVSGHIPGLTETMPLHIETLYNGYQTV
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
AAFAMAALLALIAMTTVLLRSFFEHDFKKASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGRSSRTGGVLLAAAVYAVVLLVLVLPLVLVVAQALATGFAPAWQSLLDPDAVAAIRLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHH
LVVTLASTAINSVGGVMAAWALTKYRFPGRGVLLVLIELPISVSPVIAGLVWLLLFGRGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
WWGALLARHNIQVAFATPGIILATLFVTFPYVARTLMPLMEQQGRDAEEAAFLLGAGFWQ
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLWRVTIPGARWALLSGILLTTARGIGEFGAVSVVSGHIPGLTETMPLHIETLYNGYQTV
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
AAFAMAALLALIAMTTVLLRSFFEHDFKKASS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]