Click here to switch to the map view.

The map label for this gene is gcd [H]

Identifier: 162146364

GI number: 162146364

Start: 532802

End: 535258

Strand: Direct

Name: gcd [H]

Synonym: GDI_0539

Alternate gene names: 162146364

Gene position: 532802-535258 (Clockwise)

Preceding gene: 162146363

Following gene: 162146365

Centisome position: 13.51

GC content: 67.28

Gene sequence:

>2457_bases
ATGCGAGACAGTCTGACGAGGGCGGGGTCGATCATAACCTCCGTCCTGCTGGCCTTGACCGGGCTCTTTCTATTCTTTGG
CGGAGCGGAACTTCTGTTCCTGGGCGGCTCCTGGTTCTATGCCCTGGCGGGTGCCGTCATGCTGGGCATCGCGGCCGGCG
CCATCCGGGCCCCGAAACTGGCTATCCGCCTCTATGCGGGGCTGCTGCTGGTCGCGACGGCCTGGTCGCTGTTCGAGGTC
GGGTTCAATATCTGGGGGCTGGAAGTGCGCCTGATGACCCTGGTCGGCATCGGGGCATGGATGCTGCTGCCGTGGGTGTG
GCGCACCAGCCCAAGCTGGCTGGCCGACAAGCGCGACATGCTCGGCGCGCTCGCCGTCGCCTGCCTGGCGCTGGTGATCA
GTTGCTTCACCTCCTATTCCATCGACGGCACGCTTCCCGCCGACCGCATGGCCGCCCAGGGCCAGCCGGACCCGGCGTCG
GACGGCGTGGCCGACGCGGACTGGACGGCCTATGGCCGCACCGTCGGCGGTGACCGCTATTCACCCCTGGGGCAGATCAC
CCGGACCAATATCAGCCACCTGCAGCGCGCCTGGATGACGCGCACGGGCGACGTCCAGCAGGACGGCGAGGGCACGGTCG
CGGGCCCGGACCAGGGGCACGAATTCAACCTGGAACTGACGCCGATCAAGGTTGGAAACACGCTGTACCTGTGCACCCCG
CATAGCTGGGTGATGGCGCTGGACGCCGCGACCGGCAAGGTCAAGTGGAAGTTCGACCCGCACCCGGCCACCGCCGACCT
GGCGAAGAACGTCTATCTGGCCTGCCGTGGCGTCAGCTATTATCGGATTCCCGATGACATCCAGACCAGTTGCCGCACGC
GCATCTATTCGCCGGTCGCCGACGTGCGCATGGTCGCGCTGGATGCCGAAACGGGCAAGCCGTGCGAGGATTTCGGCGAT
CATGGCTTCATTTCCATGCGCGATTACCTGGGCCATGTGCCGCATGGCTTCCATTTCATCACCTCGCCCCCGATGGTCGC
CAAGAACCGCCTGATCACCGGCGGCTGGATCTTCGACAACCAGGCCAATTTCGAGCCCTCGGGCGCCATCCGCGCCTTTG
ACGCCACCACCGGTGCCATCGCCTGGGCCTGGGACGCCGGCCACACGCCGGAAACCTGGACGCCCGGCCCGAACGACGTG
CTGACGCGCGACACCCCGAATGCCTGGGGCGTCTATACGGCCGACCTCAACCTGGGGCTGGTCTACATCCCCACGGGCAA
CTCGCCGCCCGACAACTGGGGCGGTTCGCGCCGTCCGTTCGACGACGCCACGTCGTCGGCGACCATCGCGCTGGACATCG
TGACGGGTGAACGCCGCTGGACCTACCAGACCGTGCATCACGACCTGTGGGACATGGACATTCCCTCCGGCCCGTCCATG
GTCGACCTGCCCGGGCAGAACGGCGAGAGCGTCCCGGCACTGGTGCAGAGCACGAAGCGCGGCGAATTCTTCGTCCTCGA
CCGCCGCACCGGCCAGCCGGTTCCGGGCTATCCGGTGGAAGAGCGCCCCGTTCCCACGGCCGGCCACGCGCCGGACGACC
GTGTCTCTCCGACACAGCCGTACCCCGCCGCCATGCCCAGCCTGACGCCCGCCAACCTGAAGGAGAGCGACATGTGGGGC
GCGACGCTGCTGGACCAGATGCTCTGCCGGATCGAGTATCGCCAGTCGGCCTATGAAGGCCAGTTCACGCCGCCCCATGT
GGGCAAGACGACCATCGTCTATCCGGCGTTCTACGGCGTCGTCGACTGGCAGGGCATCACGATCGACCCCCAGCGGAAGA
TCCTGCTGGCCAATGCCAGCTACCTGCCGTTCCGCATCAGGCTGGAAAAGCGCCAGACGCTGGAAGCCCCGGGGACCCTG
CCGAAATGGAATGGCCAGGGCGAGGAACCCGCGGCCAAGGGCGACGCCCTGTCCGTGTCGCCGGATTACGGCACGCCCTA
TATCGCCTATACCAACCCGTGGCTGAACCCGCTGCAGATTCCCTGCAAGGGCCCGGTCTGGGGCACGCTGACCGCGATCG
ACCTGGTGACGAAGAAGATCGTCTGGCAGCACCCGGTCGGCACGACGCGCGATACGGGCCCGTTCCGGACCCACAACAAC
CTGCCCCTGCCGACCGGCATGTATAATATCGGCGGCAATATCGTGACCAAGGGCGGCGTGGTGTTCATGGGCGCCACGGC
GGACGACTACCTGCGTGCCTTCGACCTGGCGACCGGCCAGGTCATCTGGCGCGACCGCCTGCCGGCGGGGGGCCAGGCCA
CCCCCATGTCCTACGAGGTCGGCGGCAAGCAGTACGTCCTGATGGCCGCCGGCGGCCATGGCGGGCTGGGAACGCGCAGC
GGCGACTACATCATCGCCTACACGCTCGACGGCACGCAGGGCGCGACGGTCCAGTAA

Upstream 100 bases:

>100_bases
GCGGGGGTCATGCTGATCACGCATGCTGGCCGCAGGAAGCCGTGAAGTGCCGAGACTCACACGCTGCGCGGTCCATGGAA
CATGTGGAGAAACACGCGGC

Downstream 100 bases:

>100_bases
ACGCAAGACCATCCTTGCGCGGGCATCCGGTCCAGGCCGGATGCCCATTTCCTTCACGAAAGCGCCCCCCTATGTATCTG
ACAGAAAGGTCGGGATGGCC

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 818; Mature: 818

Protein sequence:

>818_residues
MRDSLTRAGSIITSVLLALTGLFLFFGGAELLFLGGSWFYALAGAVMLGIAAGAIRAPKLAIRLYAGLLLVATAWSLFEV
GFNIWGLEVRLMTLVGIGAWMLLPWVWRTSPSWLADKRDMLGALAVACLALVISCFTSYSIDGTLPADRMAAQGQPDPAS
DGVADADWTAYGRTVGGDRYSPLGQITRTNISHLQRAWMTRTGDVQQDGEGTVAGPDQGHEFNLELTPIKVGNTLYLCTP
HSWVMALDAATGKVKWKFDPHPATADLAKNVYLACRGVSYYRIPDDIQTSCRTRIYSPVADVRMVALDAETGKPCEDFGD
HGFISMRDYLGHVPHGFHFITSPPMVAKNRLITGGWIFDNQANFEPSGAIRAFDATTGAIAWAWDAGHTPETWTPGPNDV
LTRDTPNAWGVYTADLNLGLVYIPTGNSPPDNWGGSRRPFDDATSSATIALDIVTGERRWTYQTVHHDLWDMDIPSGPSM
VDLPGQNGESVPALVQSTKRGEFFVLDRRTGQPVPGYPVEERPVPTAGHAPDDRVSPTQPYPAAMPSLTPANLKESDMWG
ATLLDQMLCRIEYRQSAYEGQFTPPHVGKTTIVYPAFYGVVDWQGITIDPQRKILLANASYLPFRIRLEKRQTLEAPGTL
PKWNGQGEEPAAKGDALSVSPDYGTPYIAYTNPWLNPLQIPCKGPVWGTLTAIDLVTKKIVWQHPVGTTRDTGPFRTHNN
LPLPTGMYNIGGNIVTKGGVVFMGATADDYLRAFDLATGQVIWRDRLPAGGQATPMSYEVGGKQYVLMAAGGHGGLGTRS
GDYIIAYTLDGTQGATVQ

Sequences:

>Translated_818_residues
MRDSLTRAGSIITSVLLALTGLFLFFGGAELLFLGGSWFYALAGAVMLGIAAGAIRAPKLAIRLYAGLLLVATAWSLFEV
GFNIWGLEVRLMTLVGIGAWMLLPWVWRTSPSWLADKRDMLGALAVACLALVISCFTSYSIDGTLPADRMAAQGQPDPAS
DGVADADWTAYGRTVGGDRYSPLGQITRTNISHLQRAWMTRTGDVQQDGEGTVAGPDQGHEFNLELTPIKVGNTLYLCTP
HSWVMALDAATGKVKWKFDPHPATADLAKNVYLACRGVSYYRIPDDIQTSCRTRIYSPVADVRMVALDAETGKPCEDFGD
HGFISMRDYLGHVPHGFHFITSPPMVAKNRLITGGWIFDNQANFEPSGAIRAFDATTGAIAWAWDAGHTPETWTPGPNDV
LTRDTPNAWGVYTADLNLGLVYIPTGNSPPDNWGGSRRPFDDATSSATIALDIVTGERRWTYQTVHHDLWDMDIPSGPSM
VDLPGQNGESVPALVQSTKRGEFFVLDRRTGQPVPGYPVEERPVPTAGHAPDDRVSPTQPYPAAMPSLTPANLKESDMWG
ATLLDQMLCRIEYRQSAYEGQFTPPHVGKTTIVYPAFYGVVDWQGITIDPQRKILLANASYLPFRIRLEKRQTLEAPGTL
PKWNGQGEEPAAKGDALSVSPDYGTPYIAYTNPWLNPLQIPCKGPVWGTLTAIDLVTKKIVWQHPVGTTRDTGPFRTHNN
LPLPTGMYNIGGNIVTKGGVVFMGATADDYLRAFDLATGQVIWRDRLPAGGQATPMSYEVGGKQYVLMAAGGHGGLGTRS
GDYIIAYTLDGTQGATVQ
>Mature_818_residues
MRDSLTRAGSIITSVLLALTGLFLFFGGAELLFLGGSWFYALAGAVMLGIAAGAIRAPKLAIRLYAGLLLVATAWSLFEV
GFNIWGLEVRLMTLVGIGAWMLLPWVWRTSPSWLADKRDMLGALAVACLALVISCFTSYSIDGTLPADRMAAQGQPDPAS
DGVADADWTAYGRTVGGDRYSPLGQITRTNISHLQRAWMTRTGDVQQDGEGTVAGPDQGHEFNLELTPIKVGNTLYLCTP
HSWVMALDAATGKVKWKFDPHPATADLAKNVYLACRGVSYYRIPDDIQTSCRTRIYSPVADVRMVALDAETGKPCEDFGD
HGFISMRDYLGHVPHGFHFITSPPMVAKNRLITGGWIFDNQANFEPSGAIRAFDATTGAIAWAWDAGHTPETWTPGPNDV
LTRDTPNAWGVYTADLNLGLVYIPTGNSPPDNWGGSRRPFDDATSSATIALDIVTGERRWTYQTVHHDLWDMDIPSGPSM
VDLPGQNGESVPALVQSTKRGEFFVLDRRTGQPVPGYPVEERPVPTAGHAPDDRVSPTQPYPAAMPSLTPANLKESDMWG
ATLLDQMLCRIEYRQSAYEGQFTPPHVGKTTIVYPAFYGVVDWQGITIDPQRKILLANASYLPFRIRLEKRQTLEAPGTL
PKWNGQGEEPAAKGDALSVSPDYGTPYIAYTNPWLNPLQIPCKGPVWGTLTAIDLVTKKIVWQHPVGTTRDTGPFRTHNN
LPLPTGMYNIGGNIVTKGGVVFMGATADDYLRAFDLATGQVIWRDRLPAGGQATPMSYEVGGKQYVLMAAGGHGGLGTRS
GDYIIAYTLDGTQGATVQ

Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=807, Percent_Identity=42.7509293680297, Blast_Score=603, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 88841; Mature: 88841

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSLTRAGSIITSVLLALTGLFLFFGGAELLFLGGSWFYALAGAVMLGIAAGAIRAPKL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHH
AIRLYAGLLLVATAWSLFEVGFNIWGLEVRLMTLVGIGAWMLLPWVWRTSPSWLADKRDM
HHHHHHHHHHHHHHHHHHHHCCCEEEHEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGALAVACLALVISCFTSYSIDGTLPADRMAAQGQPDPASDGVADADWTAYGRTVGGDRY
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCC
SPLGQITRTNISHLQRAWMTRTGDVQQDGEGTVAGPDQGHEFNLELTPIKVGNTLYLCTP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEECC
HSWVMALDAATGKVKWKFDPHPATADLAKNVYLACRGVSYYRIPDDIQTSCRTRIYSPVA
CCEEEEEECCCCEEEEEECCCCCHHHHHCCEEEEEECCEEEECCHHHHHHHHHHHCCCCC
DVRMVALDAETGKPCEDFGDHGFISMRDYLGHVPHGFHFITSPPMVAKNRLITGGWIFDN
CEEEEEEECCCCCCHHHHCCCCEEEHHHHHCCCCCCCEEECCCCHHHCCCEEECEEEECC
QANFEPSGAIRAFDATTGAIAWAWDAGHTPETWTPGPNDVLTRDTPNAWGVYTADLNLGL
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCEEE
VYIPTGNSPPDNWGGSRRPFDDATSSATIALDIVTGERRWTYQTVHHDLWDMDIPSGPSM
EEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEHHHHHHHHCCCCCCCCCE
VDLPGQNGESVPALVQSTKRGEFFVLDRRTGQPVPGYPVEERPVPTAGHAPDDRVSPTQP
EECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YPAAMPSLTPANLKESDMWGATLLDQMLCRIEYRQSAYEGQFTPPHVGKTTIVYPAFYGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECE
VDWQGITIDPQRKILLANASYLPFRIRLEKRQTLEAPGTLPKWNGQGEEPAAKGDALSVS
EECCCEEECCCCEEEEECCCCCEEEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEC
PDYGTPYIAYTNPWLNPLQIPCKGPVWGTLTAIDLVTKKIVWQHPVGTTRDTGPFRTHNN
CCCCCCEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCC
LPLPTGMYNIGGNIVTKGGVVFMGATADDYLRAFDLATGQVIWRDRLPAGGQATPMSYEV
CCCCCCEEECCCEEEECCCEEEEECCHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEC
GGKQYVLMAAGGHGGLGTRSGDYIIAYTLDGTQGATVQ
CCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRDSLTRAGSIITSVLLALTGLFLFFGGAELLFLGGSWFYALAGAVMLGIAAGAIRAPKL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHH
AIRLYAGLLLVATAWSLFEVGFNIWGLEVRLMTLVGIGAWMLLPWVWRTSPSWLADKRDM
HHHHHHHHHHHHHHHHHHHHCCCEEEHEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGALAVACLALVISCFTSYSIDGTLPADRMAAQGQPDPASDGVADADWTAYGRTVGGDRY
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCCC
SPLGQITRTNISHLQRAWMTRTGDVQQDGEGTVAGPDQGHEFNLELTPIKVGNTLYLCTP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEECC
HSWVMALDAATGKVKWKFDPHPATADLAKNVYLACRGVSYYRIPDDIQTSCRTRIYSPVA
CCEEEEEECCCCEEEEEECCCCCHHHHHCCEEEEEECCEEEECCHHHHHHHHHHHCCCCC
DVRMVALDAETGKPCEDFGDHGFISMRDYLGHVPHGFHFITSPPMVAKNRLITGGWIFDN
CEEEEEEECCCCCCHHHHCCCCEEEHHHHHCCCCCCCEEECCCCHHHCCCEEECEEEECC
QANFEPSGAIRAFDATTGAIAWAWDAGHTPETWTPGPNDVLTRDTPNAWGVYTADLNLGL
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEECCCCCCCEEEEEECCEEE
VYIPTGNSPPDNWGGSRRPFDDATSSATIALDIVTGERRWTYQTVHHDLWDMDIPSGPSM
EEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEHHHHHHHHCCCCCCCCCE
VDLPGQNGESVPALVQSTKRGEFFVLDRRTGQPVPGYPVEERPVPTAGHAPDDRVSPTQP
EECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YPAAMPSLTPANLKESDMWGATLLDQMLCRIEYRQSAYEGQFTPPHVGKTTIVYPAFYGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECE
VDWQGITIDPQRKILLANASYLPFRIRLEKRQTLEAPGTLPKWNGQGEEPAAKGDALSVS
EECCCEEECCCCEEEEECCCCCEEEEEECCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEC
PDYGTPYIAYTNPWLNPLQIPCKGPVWGTLTAIDLVTKKIVWQHPVGTTRDTGPFRTHNN
CCCCCCEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCC
LPLPTGMYNIGGNIVTKGGVVFMGATADDYLRAFDLATGQVIWRDRLPAGGQATPMSYEV
CCCCCCEEECCCEEEECCCEEEEECCHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEC
GGKQYVLMAAGGHGGLGTRSGDYIIAYTLDGTQGATVQ
CCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]