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The map label for this gene is idhA

Identifier: 162146194

GI number: 162146194

Start: 379312

End: 380325

Strand: Direct

Name: idhA

Synonym: GDI_0366

Alternate gene names: 162146194

Gene position: 379312-380325 (Clockwise)

Preceding gene: 162146193

Following gene: 162146196

Centisome position: 9.62

GC content: 65.58

Gene sequence:

>1014_bases
ATGACACTCGGAATCGGCGTGATCGGTACGGGCGCGATCGGCCAGGATCATATCAGGCGCGTCAGCCGGGCCCTGTCGGG
CGGAAGGATCGTCGCCCTGAACGACATCAATGCGGACAATGCCCGCAGGGCGGCGCAGGAATGGGCACCCGATGCGGTGA
TATGCGACACCGCCCGCGACCTGGTCGCCCGGCCGGACGTGCAGGCCGTCATGGTCACGTCCTGGGGCGGCACGCACGCG
GAATACGTGCTGGACGCGATCGCGGCGGGCAAGCCCGTCTTCTGCGAAAAGCCGCTGGCGACCAACGCGGCCGACTGCCT
GCGGATCATGGAAGCCGAAATGGCGCGTGGCCGGCGGCTGGTGCAGGTCGGCTTCAACCGGCGTTATGATTCCGGCTATC
TCGACCTCAAGGCCATTCTGGATAACGGCACCATCGGCGACGTACTGATGGTCCACGCCATGCACCGCAACCAGCGCGTG
GGGCCGAACTACAAGACCGAGATGGCCATCACCGACACGCTGGTCCATGAACTGGACGTGCATCGCTGGCTGCTGGATGG
CGAATACGTCTCGGCGCAGGTCATCTTCCCCCGCCGCACCAGCAAGGCGCTGCCCCACATGCGCGACCCGCAGATCGCCC
TGCTGGAAACGAAGCGCGGCATCCGCATCGATGTCGAAATCTTCGTCAACTGCCAGTACGGCTACGACATCCAGTGCGCC
GTCGTCGGCGAACTGGGGCAGGCCAACCTGCCGGACCCGCCCGCCGTTCCCGTCAAGACGGGCGAGACACTGTCACGCCA
CATCATGAACGACTGGAAATACCGCTTCATCGACGCCTATGACGCGGAAATCCAGGATTTCATCGACCGGGCCTCCACCG
GCTCGCCGGCCGGCCCGGATTCCTGGGCGGGCTATGCGGCCTCCGTCGCGGCCGATGCCTGCGTCCGCGCGCAGGAAAGC
GGGCGGATCGAACCGATCGAGATGATCGCGAAACCGGCCTTCTACAGCCGGTAA

Upstream 100 bases:

>100_bases
CTGGCCGGAAAGTGCCCGCGCGGGTGCCGAATTCGTCATGCCCACACTGGGCTGATCCGGATCGCTTCCAGAAAACCAAG
AACAGAAAACGAGAAGCCAC

Downstream 100 bases:

>100_bases
TGCCCGGATTCGGCGGGGACGCCCCGATCGAGGCACCCCGCCGAATCCGTGAAATCAGTACCCCGGTGGCGGCGGCGGCG
GGGGCGCGGCGGGGTATGGC

Product: inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTLGIGVIGTGAIGQDHIRRVSRALSGGRIVALNDINADNARRAAQEWAPDAVICDTARDLVARPDVQAVMVTSWGGTHA
EYVLDAIAAGKPVFCEKPLATNAADCLRIMEAEMARGRRLVQVGFNRRYDSGYLDLKAILDNGTIGDVLMVHAMHRNQRV
GPNYKTEMAITDTLVHELDVHRWLLDGEYVSAQVIFPRRTSKALPHMRDPQIALLETKRGIRIDVEIFVNCQYGYDIQCA
VVGELGQANLPDPPAVPVKTGETLSRHIMNDWKYRFIDAYDAEIQDFIDRASTGSPAGPDSWAGYAASVAADACVRAQES
GRIEPIEMIAKPAFYSR

Sequences:

>Translated_337_residues
MTLGIGVIGTGAIGQDHIRRVSRALSGGRIVALNDINADNARRAAQEWAPDAVICDTARDLVARPDVQAVMVTSWGGTHA
EYVLDAIAAGKPVFCEKPLATNAADCLRIMEAEMARGRRLVQVGFNRRYDSGYLDLKAILDNGTIGDVLMVHAMHRNQRV
GPNYKTEMAITDTLVHELDVHRWLLDGEYVSAQVIFPRRTSKALPHMRDPQIALLETKRGIRIDVEIFVNCQYGYDIQCA
VVGELGQANLPDPPAVPVKTGETLSRHIMNDWKYRFIDAYDAEIQDFIDRASTGSPAGPDSWAGYAASVAADACVRAQES
GRIEPIEMIAKPAFYSR
>Mature_336_residues
TLGIGVIGTGAIGQDHIRRVSRALSGGRIVALNDINADNARRAAQEWAPDAVICDTARDLVARPDVQAVMVTSWGGTHAE
YVLDAIAAGKPVFCEKPLATNAADCLRIMEAEMARGRRLVQVGFNRRYDSGYLDLKAILDNGTIGDVLMVHAMHRNQRVG
PNYKTEMAITDTLVHELDVHRWLLDGEYVSAQVIFPRRTSKALPHMRDPQIALLETKRGIRIDVEIFVNCQYGYDIQCAV
VGELGQANLPDPPAVPVKTGETLSRHIMNDWKYRFIDAYDAEIQDFIDRASTGSPAGPDSWAGYAASVAADACVRAQESG
RIEPIEMIAKPAFYSR

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLG_GLUDA (A9H5B7)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001600653.1
- RefSeq:   YP_002276782.1
- ProteinModelPortal:   A9H5B7
- SMR:   A9H5B7
- GeneID:   5789781
- GeneID:   6975847
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_2417
- HOGENOM:   HBG612336
- OMA:   DWKDRFI
- ProtClustDB:   CLSK2402694
- GO:   GO:0005488
- HAMAP:   MF_01671
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C

EC number: =1.1.1.18

Molecular weight: Translated: 37033; Mature: 36901

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGIGVIGTGAIGQDHIRRVSRALSGGRIVALNDINADNARRAAQEWAPDAVICDTARD
CEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCEEECCHHH
LVARPDVQAVMVTSWGGTHAEYVLDAIAAGKPVFCEKPLATNAADCLRIMEAEMARGRRL
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCEE
VQVGFNRRYDSGYLDLKAILDNGTIGDVLMVHAMHRNQRVGPNYKTEMAITDTLVHELDV
EEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHH
HRWLLDGEYVSAQVIFPRRTSKALPHMRDPQIALLETKRGIRIDVEIFVNCQYGYDIQCA
HHEEECCCEEEEEEEECCCHHHCCCCCCCCCEEEEECCCCCEEEEEEEEEECCCCEEEEE
VVGELGQANLPDPPAVPVKTGETLSRHIMNDWKYRFIDAYDAEIQDFIDRASTGSPAGPD
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCC
SWAGYAASVAADACVRAQESGRIEPIEMIAKPAFYSR
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TLGIGVIGTGAIGQDHIRRVSRALSGGRIVALNDINADNARRAAQEWAPDAVICDTARD
EEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCEEECCHHH
LVARPDVQAVMVTSWGGTHAEYVLDAIAAGKPVFCEKPLATNAADCLRIMEAEMARGRRL
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCEE
VQVGFNRRYDSGYLDLKAILDNGTIGDVLMVHAMHRNQRVGPNYKTEMAITDTLVHELDV
EEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHH
HRWLLDGEYVSAQVIFPRRTSKALPHMRDPQIALLETKRGIRIDVEIFVNCQYGYDIQCA
HHEEECCCEEEEEEEECCCHHHCCCCCCCCCEEEEECCCCCEEEEEEEEEECCCCEEEEE
VVGELGQANLPDPPAVPVKTGETLSRHIMNDWKYRFIDAYDAEIQDFIDRASTGSPAGPD
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCCCCCC
SWAGYAASVAADACVRAQESGRIEPIEMIAKPAFYSR
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA