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The map label for this gene is ptnB [H]

Identifier: 162146171

GI number: 162146171

Start: 355192

End: 356619

Strand: Direct

Name: ptnB [H]

Synonym: GDI_0343

Alternate gene names: 162146171

Gene position: 355192-356619 (Clockwise)

Preceding gene: 162146170

Following gene: 162146172

Centisome position: 9.01

GC content: 65.13

Gene sequence:

>1428_bases
ATGACCATGATCGATTCTGTCGTCGGCTTCAGCGGCCTGATCGCATCCATGCTGTTCATATACGGGCTGAAGGGCATGTC
GTCCCCGGTCACGGCGGTGCGGGGCATCGTCACGGCCGGCTGGGGCATGGCGTTCGTCGTCGGGCTCTGCTTCCTGCAGG
TCTTCGGGGTGCAGGGTGCCGCTCGGCCGCATCTGCCGGCCAACCTGGCGCTCGCGGTCCTGGCATTGGTCCTGGGCGGA
AGCTGGGCCGCCTGGAAGGGCAGGACCGTCGCCATGACGGCCATGCCGCAGATGGTGGCGCTCTATAACGGCATGGGGGG
CGGCGCGGCGGCGGCGGTGGCGGCCGTGGCGCTGCTGCGGCACCAGGAAGGCTCGGCCCTGCATTTCGGCGTGACGGTCA
CGGGCGCGCTGATCGGCTGCGTGTCGCTGACCGGCTCGCTGGTCGCATGGGCCAAGCTGGACGGGCGCATGAAGAATCCC
ATCCGTTTCGGCGGCCAGCAGGCGTTCAATGCGATCGTGTTCTTCGCCACGATCCTGCTGGGCGGCCTGGTGGTGGCGAC
GCAGATCACCGGATCGCAGCAGGCGGGGCTGTACGCCGAACTGTTCTTCGCCGGCGCGCTGTTTTTCGGGCTGTGCATGA
CCGTGCCGATCGGCGGCGCGGACATGCCGGTCGTCATTTCGCTCTACAACACCTTCACCGGCCTGGCCGTGGGGCTGGAA
GGCTATGTCATGGCCAATCCGGCGCTGATGATCGCCGGCATGGTCGTGGGGGCGGCGGGAACGCTGCTGACGGTCCTGAT
GGCCAAGGCCATGAATCGGTCGCTGGCCAATGTCCTGTTCAGCAATTTCGGGGCATCCGCCACGCAGGTGGCGGCGGGGC
CGCAGGGGCAGATGAAGTCGGTCGATCCGGCCGACGCGGCGACGTCGATGCGCTATGCGTCCAGCGTCATCATCATTCCC
GGCTACGGGCTTGCCGTCGCCCAGGCGCAGCAGAAGCTCTATGAATTCGTCAAGATGCTGCAAGCCGCCGGCGTGGACGT
GAAATTCGCGATCCATCCCGTTGCCGGCCGTATGCCCGGCCACATGAACGTGCTGCTGGCCGAGGCCAATGTGCCGTACG
ACATGATCTTCGACATGGACGACATCAACGACAGCTTCGCGTCAACCGACGTGGCGCTGGTGATCGGCGCGAACGATGTC
GTCAACCCTTCGGCGCGGACGGACAGGACATCGCCCCTCTACGGCATGCCGATCCTGAACGCCGACCAGGCGAAACAGGT
GTTCGTCATCAAGCGCGGGCAGGGGGCCGGGTATTCCGGTGTCCAGAATCCGCTGTTCTTCGAGAAGAATACGTCGATGG
TCTATGGTGACGCACAGGCCGTACTGACCAAGATGGTCGAGTCATTGAAGGCACTTGGAACGAACTGA

Upstream 100 bases:

>100_bases
ACCGCATGCTGGCGATGTTCCGCCCCAGTATCGCCCCGGCCATCGCTCCGGCCACCGCCCCGCCGGGATCGAAGCCCGCC
GGTGACCAAAAGGCGGCATC

Downstream 100 bases:

>100_bases
TTGCATCAGAATGTGTTCAAAATGCGGTGTGGGGCGTCGATCGCGCGCGCATTACTGTCGGTTCCTCGTTCGCGTTTTCA
TGGGCGATGGGTTATGCTGC

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTMIDSVVGFSGLIASMLFIYGLKGMSSPVTAVRGIVTAGWGMAFVVGLCFLQVFGVQGAARPHLPANLALAVLALVLGG
SWAAWKGRTVAMTAMPQMVALYNGMGGGAAAAVAAVALLRHQEGSALHFGVTVTGALIGCVSLTGSLVAWAKLDGRMKNP
IRFGGQQAFNAIVFFATILLGGLVVATQITGSQQAGLYAELFFAGALFFGLCMTVPIGGADMPVVISLYNTFTGLAVGLE
GYVMANPALMIAGMVVGAAGTLLTVLMAKAMNRSLANVLFSNFGASATQVAAGPQGQMKSVDPADAATSMRYASSVIIIP
GYGLAVAQAQQKLYEFVKMLQAAGVDVKFAIHPVAGRMPGHMNVLLAEANVPYDMIFDMDDINDSFASTDVALVIGANDV
VNPSARTDRTSPLYGMPILNADQAKQVFVIKRGQGAGYSGVQNPLFFEKNTSMVYGDAQAVLTKMVESLKALGTN

Sequences:

>Translated_475_residues
MTMIDSVVGFSGLIASMLFIYGLKGMSSPVTAVRGIVTAGWGMAFVVGLCFLQVFGVQGAARPHLPANLALAVLALVLGG
SWAAWKGRTVAMTAMPQMVALYNGMGGGAAAAVAAVALLRHQEGSALHFGVTVTGALIGCVSLTGSLVAWAKLDGRMKNP
IRFGGQQAFNAIVFFATILLGGLVVATQITGSQQAGLYAELFFAGALFFGLCMTVPIGGADMPVVISLYNTFTGLAVGLE
GYVMANPALMIAGMVVGAAGTLLTVLMAKAMNRSLANVLFSNFGASATQVAAGPQGQMKSVDPADAATSMRYASSVIIIP
GYGLAVAQAQQKLYEFVKMLQAAGVDVKFAIHPVAGRMPGHMNVLLAEANVPYDMIFDMDDINDSFASTDVALVIGANDV
VNPSARTDRTSPLYGMPILNADQAKQVFVIKRGQGAGYSGVQNPLFFEKNTSMVYGDAQAVLTKMVESLKALGTN
>Mature_474_residues
TMIDSVVGFSGLIASMLFIYGLKGMSSPVTAVRGIVTAGWGMAFVVGLCFLQVFGVQGAARPHLPANLALAVLALVLGGS
WAAWKGRTVAMTAMPQMVALYNGMGGGAAAAVAAVALLRHQEGSALHFGVTVTGALIGCVSLTGSLVAWAKLDGRMKNPI
RFGGQQAFNAIVFFATILLGGLVVATQITGSQQAGLYAELFFAGALFFGLCMTVPIGGADMPVVISLYNTFTGLAVGLEG
YVMANPALMIAGMVVGAAGTLLTVLMAKAMNRSLANVLFSNFGASATQVAAGPQGQMKSVDPADAATSMRYASSVIIIPG
YGLAVAQAQQKLYEFVKMLQAAGVDVKFAIHPVAGRMPGHMNVLLAEANVPYDMIFDMDDINDSFASTDVALVIGANDVV
NPSARTDRTSPLYGMPILNADQAKQVFVIKRGQGAGYSGVQNPLFFEKNTSMVYGDAQAVLTKMVESLKALGTN

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=419, Percent_Identity=39.1408114558473, Blast_Score=275, Evalue=7e-74,
Organism=Homo sapiens, GI122939153, Length=419, Percent_Identity=39.1408114558473, Blast_Score=275, Evalue=7e-74,
Organism=Escherichia coli, GI1787886, Length=464, Percent_Identity=40.0862068965517, Blast_Score=332, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17550456, Length=398, Percent_Identity=39.9497487437186, Blast_Score=279, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49236; Mature: 49105

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMIDSVVGFSGLIASMLFIYGLKGMSSPVTAVRGIVTAGWGMAFVVGLCFLQVFGVQGA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
ARPHLPANLALAVLALVLGGSWAAWKGRTVAMTAMPQMVALYNGMGGGAAAAVAAVALLR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHH
HQEGSALHFGVTVTGALIGCVSLTGSLVAWAKLDGRMKNPIRFGGQQAFNAIVFFATILL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHH
GGLVVATQITGSQQAGLYAELFFAGALFFGLCMTVPIGGADMPVVISLYNTFTGLAVGLE
HHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCC
GYVMANPALMIAGMVVGAAGTLLTVLMAKAMNRSLANVLFSNFGASATQVAAGPQGQMKS
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
VDPADAATSMRYASSVIIIPGYGLAVAQAQQKLYEFVKMLQAAGVDVKFAIHPVAGRMPG
CCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
HMNVLLAEANVPYDMIFDMDDINDSFASTDVALVIGANDVVNPSARTDRTSPLYGMPILN
CEEEEEEECCCCEEEEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
ADQAKQVFVIKRGQGAGYSGVQNPLFFEKNTSMVYGDAQAVLTKMVESLKALGTN
CCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TMIDSVVGFSGLIASMLFIYGLKGMSSPVTAVRGIVTAGWGMAFVVGLCFLQVFGVQGA
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
ARPHLPANLALAVLALVLGGSWAAWKGRTVAMTAMPQMVALYNGMGGGAAAAVAAVALLR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHH
HQEGSALHFGVTVTGALIGCVSLTGSLVAWAKLDGRMKNPIRFGGQQAFNAIVFFATILL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHH
GGLVVATQITGSQQAGLYAELFFAGALFFGLCMTVPIGGADMPVVISLYNTFTGLAVGLE
HHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCC
GYVMANPALMIAGMVVGAAGTLLTVLMAKAMNRSLANVLFSNFGASATQVAAGPQGQMKS
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
VDPADAATSMRYASSVIIIPGYGLAVAQAQQKLYEFVKMLQAAGVDVKFAIHPVAGRMPG
CCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
HMNVLLAEANVPYDMIFDMDDINDSFASTDVALVIGANDVVNPSARTDRTSPLYGMPILN
CEEEEEEECCCCEEEEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
ADQAKQVFVIKRGQGAGYSGVQNPLFFEKNTSMVYGDAQAVLTKMVESLKALGTN
CCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]