Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 162146168

GI number: 162146168

Start: 352184

End: 353290

Strand: Direct

Name: namA [H]

Synonym: GDI_0340

Alternate gene names: 162146168

Gene position: 352184-353290 (Clockwise)

Preceding gene: 162146167

Following gene: 162146169

Centisome position: 8.93

GC content: 71.0

Gene sequence:

>1107_bases
ATGAGCGGACCGAAACTCTTCGAACCGATCAGACTCGGCGGCCTGTCGCTGGACAACCGGATCGTCGTGGCCCCGATGTG
CCAGTATTCCGCCGTGGACGGCTGCATGACGGACTGGCACCTGATCCATCTGGGCGGCCTGGCCCTGTCCGGCGCGGGCC
TGCTGACGATCGAGGCGACCTCCGTCCTGCCGGAAGGGCGGATCACCTATGCCGATATCGGCCTGTGGGACGACGCGACC
GAGGCCGCCCTGCGCCGCACGATCGAGGGCATCCGCCCGTGGTCCGACATGCCCATCGCGCTCCAGTTGGCGCATGCGGG
GCGCAAGGCCTCGACCGACCTGCCGTGGAAGGGCGGGCGGCACCTGCCGCCGGGCTCGCCCAACGCCTGGCAGACCGTGG
CCCCGTCCGCCGTGCCGTTCGCCGAAGGCGACCACGCGCCCCAGGCCCTGGACATCGACGGATTGCGGCGGGTGCGCGAC
GCGTTCGCGGCGGCGGCCCGGCGGGCGGCCCGGCTTGGCCTGGACGCCATACAGGTCCACGGCGCGCATGGGTACCTGCT
GCACCAGTTCCTCTCCCCGCTTTCCAACCGGCGGGACGATGCGTATGGCGGCAGCCTGGAAAATCGGCTGCGCTTCCCGC
TGGAGGTCTTCGACGCGGTGCGCGAGGCCTTTCCCGACGGCCCGGTGACGATCCGCGTCTCCGGCACCGACTGGGTGCCG
GGCGGATGGGATGTCGAACAGACGATCGCGCTGGCCAAAGCGCTGGAATCCCGGGGCTGCGACGCCATCCATGTGTCCAG
CGGCGGGCTCAGCCCCCAACAGCAGATCCCGGTCCACCCCAGCTACCAGGTCCCGCTGGCCCGCGCGGTGAAGGCGGAAA
CGACCATGCCGGTGGTCGCCGTGGGCCTGATCACGGGGTTCGAGCAGGCGGAAGCGATCGTCGCGACCGGCGACGCCGAC
ATGATCGCCCTGGCCCGGACCATCCTCTACGACCCGCGCTGGCCGTGGCACGCGGCGGCGCATCTGGGCGCCCAGGTGAA
GGCTCCCGACCAGTACCTGCGCTGCCAGCCCCGGGTCCACAAGGACCTGTTCAAGACCAGGGGCTAG

Upstream 100 bases:

>100_bases
GGACCCGGAAACCGGGCAGGTGCTGCAACGGGTGATCGCTTCTCTTTTCTGAAAAAAAGAACGAAGAATGCAGCCCTGAC
CATAACCTGGGGAGCGAACC

Downstream 100 bases:

>100_bases
AGTAGTCAGTCATCGGATTCACGTGGTTAGGTGATTCCCCCTGACCACGGTCTGCGCGAAAGCCGCCTTCGGCTTCCGAC
GCCCGGACCGCACCCTGCCG

Product: NADPH dehydrogenase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSGPKLFEPIRLGGLSLDNRIVVAPMCQYSAVDGCMTDWHLIHLGGLALSGAGLLTIEATSVLPEGRITYADIGLWDDAT
EAALRRTIEGIRPWSDMPIALQLAHAGRKASTDLPWKGGRHLPPGSPNAWQTVAPSAVPFAEGDHAPQALDIDGLRRVRD
AFAAAARRAARLGLDAIQVHGAHGYLLHQFLSPLSNRRDDAYGGSLENRLRFPLEVFDAVREAFPDGPVTIRVSGTDWVP
GGWDVEQTIALAKALESRGCDAIHVSSGGLSPQQQIPVHPSYQVPLARAVKAETTMPVVAVGLITGFEQAEAIVATGDAD
MIALARTILYDPRWPWHAAAHLGAQVKAPDQYLRCQPRVHKDLFKTRG

Sequences:

>Translated_368_residues
MSGPKLFEPIRLGGLSLDNRIVVAPMCQYSAVDGCMTDWHLIHLGGLALSGAGLLTIEATSVLPEGRITYADIGLWDDAT
EAALRRTIEGIRPWSDMPIALQLAHAGRKASTDLPWKGGRHLPPGSPNAWQTVAPSAVPFAEGDHAPQALDIDGLRRVRD
AFAAAARRAARLGLDAIQVHGAHGYLLHQFLSPLSNRRDDAYGGSLENRLRFPLEVFDAVREAFPDGPVTIRVSGTDWVP
GGWDVEQTIALAKALESRGCDAIHVSSGGLSPQQQIPVHPSYQVPLARAVKAETTMPVVAVGLITGFEQAEAIVATGDAD
MIALARTILYDPRWPWHAAAHLGAQVKAPDQYLRCQPRVHKDLFKTRG
>Mature_367_residues
SGPKLFEPIRLGGLSLDNRIVVAPMCQYSAVDGCMTDWHLIHLGGLALSGAGLLTIEATSVLPEGRITYADIGLWDDATE
AALRRTIEGIRPWSDMPIALQLAHAGRKASTDLPWKGGRHLPPGSPNAWQTVAPSAVPFAEGDHAPQALDIDGLRRVRDA
FAAAARRAARLGLDAIQVHGAHGYLLHQFLSPLSNRRDDAYGGSLENRLRFPLEVFDAVREAFPDGPVTIRVSGTDWVPG
GWDVEQTIALAKALESRGCDAIHVSSGGLSPQQQIPVHPSYQVPLARAVKAETTMPVVAVGLITGFEQAEAIVATGDADM
IALARTILYDPRWPWHAAAHLGAQVKAPDQYLRCQPRVHKDLFKTRG

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=340, Percent_Identity=30.5882352941176, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787939, Length=347, Percent_Identity=29.6829971181556, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17540738, Length=224, Percent_Identity=32.5892857142857, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=245, Percent_Identity=33.8775510204082, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17564188, Length=251, Percent_Identity=30.6772908366534, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559802, Length=235, Percent_Identity=31.9148936170213, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=251, Percent_Identity=29.0836653386454, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=189, Percent_Identity=34.3915343915344, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=130, Percent_Identity=33.0769230769231, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=233, Percent_Identity=28.3261802575107, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=242, Percent_Identity=28.9256198347107, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39681; Mature: 39549

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPKLFEPIRLGGLSLDNRIVVAPMCQYSAVDGCMTDWHLIHLGGLALSGAGLLTIEAT
CCCCCCCCHHHCCCCCCCCEEEEEECHHHHHHCCCCCCEEEEEECCEEECCCCEEEEEEH
SVLPEGRITYADIGLWDDATEAALRRTIEGIRPWSDMPIALQLAHAGRKASTDLPWKGGR
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
HLPPGSPNAWQTVAPSAVPFAEGDHAPQALDIDGLRRVRDAFAAAARRAARLGLDAIQVH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GAHGYLLHQFLSPLSNRRDDAYGGSLENRLRFPLEVFDAVREAFPDGPVTIRVSGTDWVP
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
GGWDVEQTIALAKALESRGCDAIHVSSGGLSPQQQIPVHPSYQVPLARAVKAETTMPVVA
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCCCCCCCCHHHHHHHCCCCHHHH
VGLITGFEQAEAIVATGDADMIALARTILYDPRWPWHAAAHLGAQVKAPDQYLRCQPRVH
HHHHHCHHHCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHCCCCHHH
KDLFKTRG
HHHHHCCC
>Mature Secondary Structure 
SGPKLFEPIRLGGLSLDNRIVVAPMCQYSAVDGCMTDWHLIHLGGLALSGAGLLTIEAT
CCCCCCCHHHCCCCCCCCEEEEEECHHHHHHCCCCCCEEEEEECCEEECCCCEEEEEEH
SVLPEGRITYADIGLWDDATEAALRRTIEGIRPWSDMPIALQLAHAGRKASTDLPWKGGR
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
HLPPGSPNAWQTVAPSAVPFAEGDHAPQALDIDGLRRVRDAFAAAARRAARLGLDAIQVH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GAHGYLLHQFLSPLSNRRDDAYGGSLENRLRFPLEVFDAVREAFPDGPVTIRVSGTDWVP
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
GGWDVEQTIALAKALESRGCDAIHVSSGGLSPQQQIPVHPSYQVPLARAVKAETTMPVVA
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCCCCCCCCHHHHHHHCCCCHHHH
VGLITGFEQAEAIVATGDADMIALARTILYDPRWPWHAAAHLGAQVKAPDQYLRCQPRVH
HHHHHCHHHCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHCCCCHHH
KDLFKTRG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA