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The map label for this gene is yjjL [H]

Identifier: 162146164

GI number: 162146164

Start: 348069

End: 349319

Strand: Reverse

Name: yjjL [H]

Synonym: GDI_0336

Alternate gene names: 162146164

Gene position: 349319-348069 (Counterclockwise)

Preceding gene: 162146165

Following gene: 162146160

Centisome position: 8.86

GC content: 72.02

Gene sequence:

>1251_bases
ATGCCGGGCGGGGCGGGCGCCGGGGTCGGGCGCCGGCGGGGGCCGACGCGGCTGGTGGTGCTGGGGCTGCTGATCGCGGC
GGGGTGCGTCAGCTATATCGACCGCACGGCGCTGGCGGTGTCCACTGTGGAAATCGGTCGGGAATTCGGGCTGTCCTATA
CCGACCTGGGCCTGCTGCTGTCGTCCTTCGCGACCGTTTACATGCTGTGCCAGATTCCTGCCGGGCTGGTCGCCGACCGG
GTACGCGCGCGGCGGCTGCTGCTGTTCAGCCTGCTGGTCTGGAGCGCCGCCCAGATCCTGTCGGCGTTCTCCACGGGCAT
GGGCGGGCTATTGGCTGCGCGCGGCCTGCTGGCCATCGGCGAGGCGCCGATCTTCCTGGCCGGGACGCGCGTGATCGCGC
TGTGGTTCGACCGGGGCCGGCGGGCCATGCCGATCGGCCTGTTCAATGCGTCCTCCGCGCTGGGGCAGGTGCTGGCCCCC
GCGCTGCTGGGCGGCATCGCCGTGCAGTTCGGCTGGCGCGCCATGTTCGGCGTCGTGGGCTGTACCAGCCTGGTCCTGGC
CGTGATATGGGCGTGGGTCTATCGCGACCCGCGCACCGTGGCGGCGGGGCGGGGCGAGACGCGCCCCCGCCCACGATCGC
CGAAGGAAATCCGCTTCCTGCTGTCGCATCGCAGCAGTTGGGCGCTGGCCGGCGGGTTCGTCGGCGTGGTCTATCTGCAA
TGGCTGTACGCGGCGTGGCTGCCGACCTACCTGCAGACGGCACGCCATGCCGCGGCGGCGCGGGCCGATTACCTGTCGTC
CCTTCCGCAACTGGCCGGATTCCTCGGGGGGCTGGGCGGCGGCGTGGTGTCCGAGGTACTGGGCCGGATCGGCTGGCCCG
CCGCGCGGGCCTGCCGCGTGCCGCTGGTCGCGGCGCTGTTCGTCGCAGCGGCCGCCACGATCCTGGCGCCGCTCTGCCCC
GCGATGGTCCTGTCGCTGGTGGCCATGTCCGTCGCGCTGTTCGCCGCCGGCATCGCCATGACCTGCGGCTGGACGCTGGG
CACGGTCCTGATCGACGACGGGTCGATCGCGACGCTGGAAGCCATCCAGAACATGGGCGGCTCGCTGGGCGGCGCCATCG
CACCGGTCCTGACCGGCGCGATCACCCAGCGGACGGGGTCCTTCACCATGGCAATGGTGGTCGCCGGCTTGGTCGCGGCG
CTGTCCGGAATCATCTACTGGGTGGGAACGGGCCGGCGTATCGAGGCATGA

Upstream 100 bases:

>100_bases
GCCACCGAACCGTTCCTGGCCGTGCGGCCGGACCGGGCCGCCGGGGCGTGCCTGGGTGGCTGAGCGGTCCGGAGGCGCGG
CGCCGCACTGGCTGGCGGCG

Downstream 100 bases:

>100_bases
GCGCCGCTTGAAAATCGGCGGTTCCACCGTTCGCGAACACGGCGGCTTGCGACACCAGATCGACAGGTCAGGGGCTCGGC
TACCAATCCCAGGGGAGGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MPGGAGAGVGRRRGPTRLVVLGLLIAAGCVSYIDRTALAVSTVEIGREFGLSYTDLGLLLSSFATVYMLCQIPAGLVADR
VRARRLLLFSLLVWSAAQILSAFSTGMGGLLAARGLLAIGEAPIFLAGTRVIALWFDRGRRAMPIGLFNASSALGQVLAP
ALLGGIAVQFGWRAMFGVVGCTSLVLAVIWAWVYRDPRTVAAGRGETRPRPRSPKEIRFLLSHRSSWALAGGFVGVVYLQ
WLYAAWLPTYLQTARHAAAARADYLSSLPQLAGFLGGLGGGVVSEVLGRIGWPAARACRVPLVAALFVAAAATILAPLCP
AMVLSLVAMSVALFAAGIAMTCGWTLGTVLIDDGSIATLEAIQNMGGSLGGAIAPVLTGAITQRTGSFTMAMVVAGLVAA
LSGIIYWVGTGRRIEA

Sequences:

>Translated_416_residues
MPGGAGAGVGRRRGPTRLVVLGLLIAAGCVSYIDRTALAVSTVEIGREFGLSYTDLGLLLSSFATVYMLCQIPAGLVADR
VRARRLLLFSLLVWSAAQILSAFSTGMGGLLAARGLLAIGEAPIFLAGTRVIALWFDRGRRAMPIGLFNASSALGQVLAP
ALLGGIAVQFGWRAMFGVVGCTSLVLAVIWAWVYRDPRTVAAGRGETRPRPRSPKEIRFLLSHRSSWALAGGFVGVVYLQ
WLYAAWLPTYLQTARHAAAARADYLSSLPQLAGFLGGLGGGVVSEVLGRIGWPAARACRVPLVAALFVAAAATILAPLCP
AMVLSLVAMSVALFAAGIAMTCGWTLGTVLIDDGSIATLEAIQNMGGSLGGAIAPVLTGAITQRTGSFTMAMVVAGLVAA
LSGIIYWVGTGRRIEA
>Mature_415_residues
PGGAGAGVGRRRGPTRLVVLGLLIAAGCVSYIDRTALAVSTVEIGREFGLSYTDLGLLLSSFATVYMLCQIPAGLVADRV
RARRLLLFSLLVWSAAQILSAFSTGMGGLLAARGLLAIGEAPIFLAGTRVIALWFDRGRRAMPIGLFNASSALGQVLAPA
LLGGIAVQFGWRAMFGVVGCTSLVLAVIWAWVYRDPRTVAAGRGETRPRPRSPKEIRFLLSHRSSWALAGGFVGVVYLQW
LYAAWLPTYLQTARHAAAARADYLSSLPQLAGFLGGLGGGVVSEVLGRIGWPAARACRVPLVAALFVAAAATILAPLCPA
MVLSLVAMSVALFAAGIAMTCGWTLGTVLIDDGSIATLEAIQNMGGSLGGAIAPVLTGAITQRTGSFTMAMVVAGLVAAL
SGIIYWVGTGRRIEA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=394, Percent_Identity=21.5736040609137, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI154350196, Length=406, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367379, Length=394, Percent_Identity=32.994923857868, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI87082320, Length=431, Percent_Identity=29.2343387470998, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789515, Length=438, Percent_Identity=26.2557077625571, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=26.4236902050114, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI87082310, Length=272, Percent_Identity=26.1029411764706, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI2367193, Length=291, Percent_Identity=21.9931271477663, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=457, Percent_Identity=24.507658643326, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24584153, Length=371, Percent_Identity=23.7196765498652, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639764, Length=425, Percent_Identity=23.2941176470588, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17864456, Length=392, Percent_Identity=22.7040816326531, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654039, Length=392, Percent_Identity=22.7040816326531, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654041, Length=393, Percent_Identity=23.4096692111959, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24654037, Length=393, Percent_Identity=23.4096692111959, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43213; Mature: 43082

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGGAGAGVGRRRGPTRLVVLGLLIAAGCVSYIDRTALAVSTVEIGREFGLSYTDLGLLL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SSFATVYMLCQIPAGLVADRVRARRLLLFSLLVWSAAQILSAFSTGMGGLLAARGLLAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
EAPIFLAGTRVIALWFDRGRRAMPIGLFNASSALGQVLAPALLGGIAVQFGWRAMFGVVG
CCCEEEECCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTSLVLAVIWAWVYRDPRTVAAGRGETRPRPRSPKEIRFLLSHRSSWALAGGFVGVVYLQ
HHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
WLYAAWLPTYLQTARHAAAARADYLSSLPQLAGFLGGLGGGVVSEVLGRIGWPAARACRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
PLVAALFVAAAATILAPLCPAMVLSLVAMSVALFAAGIAMTCGWTLGTVLIDDGSIATLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCCHHHHH
AIQNMGGSLGGAIAPVLTGAITQRTGSFTMAMVVAGLVAALSGIIYWVGTGRRIEA
HHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCEECC
>Mature Secondary Structure 
PGGAGAGVGRRRGPTRLVVLGLLIAAGCVSYIDRTALAVSTVEIGREFGLSYTDLGLLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SSFATVYMLCQIPAGLVADRVRARRLLLFSLLVWSAAQILSAFSTGMGGLLAARGLLAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
EAPIFLAGTRVIALWFDRGRRAMPIGLFNASSALGQVLAPALLGGIAVQFGWRAMFGVVG
CCCEEEECCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTSLVLAVIWAWVYRDPRTVAAGRGETRPRPRSPKEIRFLLSHRSSWALAGGFVGVVYLQ
HHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
WLYAAWLPTYLQTARHAAAARADYLSSLPQLAGFLGGLGGGVVSEVLGRIGWPAARACRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
PLVAALFVAAAATILAPLCPAMVLSLVAMSVALFAAGIAMTCGWTLGTVLIDDGSIATLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCCHHHHH
AIQNMGGSLGGAIAPVLTGAITQRTGSFTMAMVVAGLVAALSGIIYWVGTGRRIEA
HHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]