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The map label for this gene is gcd [H]

Identifier: 162146153

GI number: 162146153

Start: 333895

End: 336342

Strand: Direct

Name: gcd [H]

Synonym: GDI_0325

Alternate gene names: 162146153

Gene position: 333895-336342 (Clockwise)

Preceding gene: 162146150

Following gene: 162146154

Centisome position: 8.47

GC content: 64.46

Gene sequence:

>2448_bases
ATGAAGATAAACCGGAGAAGCGCCTTGGGACAAACGCGACCTGTTCCTCTTTCCTTGCGGATCACTGGATTTTTTCTGAT
CATCTATGGCGTCGTCATGACGATTCCGGGCGTGTGGCTGATCACGCTGGGCGACAGCAGTTACTATACTGTCGCGGGCG
TGCTGACGCTGGTCAGCGGCGGCCTGATCGTCACCGGGCGGGGTGCGGGGCTGTGGGTCTATGCTATCATGCTGGGCAGC
ACCCTGGTATGGGCGCTGTCACGGGTGGGGCTTGACGGATGGCGCCTGCTGCCGCCCCTGGCGCTGCCATCCGGCATCGG
CCTGTGGGTTTTCGGCCCGTGGGTGGCCGGCCGCCTGCGGGACCCCAATGGGCGCGTCCGCATCAATACGACCGTACTGG
GCGGCATGGGCAGTTGCGCCGCCCTGTTCGTCTTCCTGTTCGCGTGCGGATGGGCCGTTACGGCCTCGCGCACGATCCAG
CACAATCCGTTTCCGACGGACCATCGTGACGGCGCGCTGATCAATGCGGAATCCCTGGCCAACAATGAATGGCGCTATAT
GGGCGGTACCTCGGCCGGTGACCGCTTCGGAATGGCGAGCCAGATCACCGCGGACAATGCCCATGACCTGAAACCGGCCT
GGATCTTCCATACCGGGGATGTGCCGCGCGCCGACGAAAACGCGCGCGGACGCGAATTCAGCTTCGAGGCGACGCCGCTG
AAGATCGGCGACAATCTTGTCTTCTGCACGCCGCATCGCGATGTCGTGGCCGTGGACGCCACCACCGGCAAGCAGGTGTG
GCGATACAGCCCCAATGGGGATTACGGCCAGAATATCTACCAGGCCTGCCGGGGCGTATCCTATTTCGAGGCGCCCGCCG
GATCGCCCTGCCCGCATCGCATCATTTCCACCGATTCCGGCTCGCCCCCGACCCTGTTCGCGCTTGACGCCGATACCGGT
CGCCTGTGCCCGGCATTCGGTCATGACGGCGTTGTCGACCTGCGTGAAGGCATGGGCGTCATCCCGGCGGGATTCCACTT
CATCACGTCTCCGCCGATGGTGATGAACAATCGCATCATGCTGAGCGGCTGGGTCTACGACAACCAGACCGTGGGCGAGC
CGTCGGGCGTCATTCGCGGCTTCGACGCGACCACGGGCCAACTGGCCTGGGGGTGGGATATCGGGCATACGCCCGCCAAC
CGCCCGTTGAATCCGGGTGAAACCTTCACGCGCGGCACCCCCAATGGCTGGGGCGTCTATACGGCCGATCCCGCCCTGAA
CATGGTCTATGTGCCGCTGGGTATCGCGACGCCCGATTATTACGGCGTCAAGCGCCGTCCCTTCGACGAGCAGTATGATA
CGTCCCTGGTGGCGCTGGACATCACGACGGGCGAGGAACGCTGGCACTTCCAGACCGTCCATCACGACCTGTGGGATTTC
GACCTTCCGGTCGGCCCGTCGCTGGTCGATCTGCCGGACAGCAGCGGCCGGATGACCCCCGCGCTGGTCCAGACCACCAA
GCAGGGCGAGCTGTTCGTGCTCGACCGTCGTACCGGCAAGCCGTTCTACCGTGTCGAGGAACGACCGGTACCGGGAGGCA
CCGTTGCGGACGAACGGTATTCCCCGACGCAGCCCTATTCGCCGGACATGCCGAACCTGCGCCGGTCCGACCCGACGACG
GACGATCTGTGGGGGATCACGCCGTTCGACCAGATGGCCTGTCGCATCGCCTTCAAACGCATGAGGTTCCAGGGCCTGTT
CACACCCCCCAGCGCGCAGGGAACGATCGGGTTTCCGGCATTCGACGGCGTGGACGACTGGTATGGCGCGACGATCGATC
CCACGCGCGGCGTCCTGTATGTCAACACGACCTATATCCCGTTCACCATGCAGCTTGTCCCGTATGGGCAGGCCCTGAAG
CAGGGCCTGTTCAAGCCATGGGCCGGATGGAACCAGCCCTATCCCGAGCCGACTTTTTCGAACAATCCGCAGCATGGCCT
GCCCTATTCCGCCGTCATCAAGCCGTGGCTGGGCATTTTCGGGGCGCCGTGCCTGGCGCCGCCCTGGGGCAGGACGCAGG
CCATCGACCTAGTGCATCATCGGAAGATCTGGGAACGCGCGCTGGGAACGACGAAGAATGTCGGCCCGACCAATGCCCTG
CGTATGCCCGTCGGGCTGCCGACCGGCATCTTCAGCATGGGCGGCACGCTGACGACCCCGACCGGACTGGTCTTCATGGG
CGCCACTGCCGACCAGGCGTTCCGTGTCCTCGACGGGCGGAACGGCCGGATTCTTTATGAAACCACCCTCGATGCCGGCG
GGAACGCGACCCCGATGACCTATATGGGCAAGGACGGGCGGCAATATGTGGTGCTCGCGGTGGGCGGGCATGGCGGCCTC
AAGACACGGAACGGCGACGAGGTCGTGGCTTTCGCCCTGCCTAAATGA

Upstream 100 bases:

>100_bases
CGACAGGCCGCGATCCCGGGTCCCGCCGCCTCGGCGCGTCTTCGGCCAGAAACCTTATGACATATTCGTGGTTAGTATCG
TTGCATGATGCTGCGCCTGC

Downstream 100 bases:

>100_bases
CGCGTGAGAAACCGGACCCGCTTCGCCGCTCGGGCGAAGCGGGTCCAGGCGGCGCGGCGCTTCCCCTTGGTGAGTATCCC
CCCATCATAATTCCTCCGAT

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MKINRRSALGQTRPVPLSLRITGFFLIIYGVVMTIPGVWLITLGDSSYYTVAGVLTLVSGGLIVTGRGAGLWVYAIMLGS
TLVWALSRVGLDGWRLLPPLALPSGIGLWVFGPWVAGRLRDPNGRVRINTTVLGGMGSCAALFVFLFACGWAVTASRTIQ
HNPFPTDHRDGALINAESLANNEWRYMGGTSAGDRFGMASQITADNAHDLKPAWIFHTGDVPRADENARGREFSFEATPL
KIGDNLVFCTPHRDVVAVDATTGKQVWRYSPNGDYGQNIYQACRGVSYFEAPAGSPCPHRIISTDSGSPPTLFALDADTG
RLCPAFGHDGVVDLREGMGVIPAGFHFITSPPMVMNNRIMLSGWVYDNQTVGEPSGVIRGFDATTGQLAWGWDIGHTPAN
RPLNPGETFTRGTPNGWGVYTADPALNMVYVPLGIATPDYYGVKRRPFDEQYDTSLVALDITTGEERWHFQTVHHDLWDF
DLPVGPSLVDLPDSSGRMTPALVQTTKQGELFVLDRRTGKPFYRVEERPVPGGTVADERYSPTQPYSPDMPNLRRSDPTT
DDLWGITPFDQMACRIAFKRMRFQGLFTPPSAQGTIGFPAFDGVDDWYGATIDPTRGVLYVNTTYIPFTMQLVPYGQALK
QGLFKPWAGWNQPYPEPTFSNNPQHGLPYSAVIKPWLGIFGAPCLAPPWGRTQAIDLVHHRKIWERALGTTKNVGPTNAL
RMPVGLPTGIFSMGGTLTTPTGLVFMGATADQAFRVLDGRNGRILYETTLDAGGNATPMTYMGKDGRQYVVLAVGGHGGL
KTRNGDEVVAFALPK

Sequences:

>Translated_815_residues
MKINRRSALGQTRPVPLSLRITGFFLIIYGVVMTIPGVWLITLGDSSYYTVAGVLTLVSGGLIVTGRGAGLWVYAIMLGS
TLVWALSRVGLDGWRLLPPLALPSGIGLWVFGPWVAGRLRDPNGRVRINTTVLGGMGSCAALFVFLFACGWAVTASRTIQ
HNPFPTDHRDGALINAESLANNEWRYMGGTSAGDRFGMASQITADNAHDLKPAWIFHTGDVPRADENARGREFSFEATPL
KIGDNLVFCTPHRDVVAVDATTGKQVWRYSPNGDYGQNIYQACRGVSYFEAPAGSPCPHRIISTDSGSPPTLFALDADTG
RLCPAFGHDGVVDLREGMGVIPAGFHFITSPPMVMNNRIMLSGWVYDNQTVGEPSGVIRGFDATTGQLAWGWDIGHTPAN
RPLNPGETFTRGTPNGWGVYTADPALNMVYVPLGIATPDYYGVKRRPFDEQYDTSLVALDITTGEERWHFQTVHHDLWDF
DLPVGPSLVDLPDSSGRMTPALVQTTKQGELFVLDRRTGKPFYRVEERPVPGGTVADERYSPTQPYSPDMPNLRRSDPTT
DDLWGITPFDQMACRIAFKRMRFQGLFTPPSAQGTIGFPAFDGVDDWYGATIDPTRGVLYVNTTYIPFTMQLVPYGQALK
QGLFKPWAGWNQPYPEPTFSNNPQHGLPYSAVIKPWLGIFGAPCLAPPWGRTQAIDLVHHRKIWERALGTTKNVGPTNAL
RMPVGLPTGIFSMGGTLTTPTGLVFMGATADQAFRVLDGRNGRILYETTLDAGGNATPMTYMGKDGRQYVVLAVGGHGGL
KTRNGDEVVAFALPK
>Mature_815_residues
MKINRRSALGQTRPVPLSLRITGFFLIIYGVVMTIPGVWLITLGDSSYYTVAGVLTLVSGGLIVTGRGAGLWVYAIMLGS
TLVWALSRVGLDGWRLLPPLALPSGIGLWVFGPWVAGRLRDPNGRVRINTTVLGGMGSCAALFVFLFACGWAVTASRTIQ
HNPFPTDHRDGALINAESLANNEWRYMGGTSAGDRFGMASQITADNAHDLKPAWIFHTGDVPRADENARGREFSFEATPL
KIGDNLVFCTPHRDVVAVDATTGKQVWRYSPNGDYGQNIYQACRGVSYFEAPAGSPCPHRIISTDSGSPPTLFALDADTG
RLCPAFGHDGVVDLREGMGVIPAGFHFITSPPMVMNNRIMLSGWVYDNQTVGEPSGVIRGFDATTGQLAWGWDIGHTPAN
RPLNPGETFTRGTPNGWGVYTADPALNMVYVPLGIATPDYYGVKRRPFDEQYDTSLVALDITTGEERWHFQTVHHDLWDF
DLPVGPSLVDLPDSSGRMTPALVQTTKQGELFVLDRRTGKPFYRVEERPVPGGTVADERYSPTQPYSPDMPNLRRSDPTT
DDLWGITPFDQMACRIAFKRMRFQGLFTPPSAQGTIGFPAFDGVDDWYGATIDPTRGVLYVNTTYIPFTMQLVPYGQALK
QGLFKPWAGWNQPYPEPTFSNNPQHGLPYSAVIKPWLGIFGAPCLAPPWGRTQAIDLVHHRKIWERALGTTKNVGPTNAL
RMPVGLPTGIFSMGGTLTTPTGLVFMGATADQAFRVLDGRNGRILYETTLDAGGNATPMTYMGKDGRQYVVLAVGGHGGL
KTRNGDEVVAFALPK

Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=828, Percent_Identity=36.4734299516908, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 88895; Mature: 88895

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINRRSALGQTRPVPLSLRITGFFLIIYGVVMTIPGVWLITLGDSSYYTVAGVLTLVSG
CCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCC
GLIVTGRGAGLWVYAIMLGSTLVWALSRVGLDGWRLLPPLALPSGIGLWVFGPWVAGRLR
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEECCCCCCEEE
DPNGRVRINTTVLGGMGSCAALFVFLFACGWAVTASRTIQHNPFPTDHRDGALINAESLA
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEECCCEEECCCCCCCCCCCCEEEHHHHC
NNEWRYMGGTSAGDRFGMASQITADNAHDLKPAWIFHTGDVPRADENARGREFSFEATPL
CCCEEEECCCCCCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCE
KIGDNLVFCTPHRDVVAVDATTGKQVWRYSPNGDYGQNIYQACRGVSYFEAPAGSPCPHR
EECCCEEEECCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCC
IISTDSGSPPTLFALDADTGRLCPAFGHDGVVDLREGMGVIPAGFHFITSPPMVMNNRIM
EEECCCCCCCEEEEEECCCCCCCCCCCCCCEEEHHCCCCCCCCCCEEECCCCEEECCEEE
LSGWVYDNQTVGEPSGVIRGFDATTGQLAWGWDIGHTPANRPLNPGETFTRGTPNGWGVY
EEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEE
TADPALNMVYVPLGIATPDYYGVKRRPFDEQYDTSLVALDITTGEERWHFQTVHHDLWDF
ECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHCCCCCC
DLPVGPSLVDLPDSSGRMTPALVQTTKQGELFVLDRRTGKPFYRVEERPVPGGTVADERY
CCCCCCCEEECCCCCCCCCHHHHEECCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCC
SPTQPYSPDMPNLRRSDPTTDDLWGITPFDQMACRIAFKRMRFQGLFTPPSAQGTIGFPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEECCCCCCCCEECCCC
FDGVDDWYGATIDPTRGVLYVNTTYIPFTMQLVPYGQALKQGLFKPWAGWNQPYPEPTFS
CCCCCHHCCCEECCCCCEEEEEEEEEEEEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCC
NNPQHGLPYSAVIKPWLGIFGAPCLAPPWGRTQAIDLVHHRKIWERALGTTKNVGPTNAL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEE
RMPVGLPTGIFSMGGTLTTPTGLVFMGATADQAFRVLDGRNGRILYETTLDAGGNATPMT
EECCCCCCHHHHCCCEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEEEECCCCCCCCEE
YMGKDGRQYVVLAVGGHGGLKTRNGDEVVAFALPK
EECCCCCEEEEEEECCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKINRRSALGQTRPVPLSLRITGFFLIIYGVVMTIPGVWLITLGDSSYYTVAGVLTLVSG
CCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCC
GLIVTGRGAGLWVYAIMLGSTLVWALSRVGLDGWRLLPPLALPSGIGLWVFGPWVAGRLR
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEECCCCCCEEE
DPNGRVRINTTVLGGMGSCAALFVFLFACGWAVTASRTIQHNPFPTDHRDGALINAESLA
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEECCCEEECCCCCCCCCCCCEEEHHHHC
NNEWRYMGGTSAGDRFGMASQITADNAHDLKPAWIFHTGDVPRADENARGREFSFEATPL
CCCEEEECCCCCCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCE
KIGDNLVFCTPHRDVVAVDATTGKQVWRYSPNGDYGQNIYQACRGVSYFEAPAGSPCPHR
EECCCEEEECCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCC
IISTDSGSPPTLFALDADTGRLCPAFGHDGVVDLREGMGVIPAGFHFITSPPMVMNNRIM
EEECCCCCCCEEEEEECCCCCCCCCCCCCCEEEHHCCCCCCCCCCEEECCCCEEECCEEE
LSGWVYDNQTVGEPSGVIRGFDATTGQLAWGWDIGHTPANRPLNPGETFTRGTPNGWGVY
EEEEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEE
TADPALNMVYVPLGIATPDYYGVKRRPFDEQYDTSLVALDITTGEERWHFQTVHHDLWDF
ECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEHHCCCCCC
DLPVGPSLVDLPDSSGRMTPALVQTTKQGELFVLDRRTGKPFYRVEERPVPGGTVADERY
CCCCCCCEEECCCCCCCCCHHHHEECCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCC
SPTQPYSPDMPNLRRSDPTTDDLWGITPFDQMACRIAFKRMRFQGLFTPPSAQGTIGFPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEECCCCCCCCEECCCC
FDGVDDWYGATIDPTRGVLYVNTTYIPFTMQLVPYGQALKQGLFKPWAGWNQPYPEPTFS
CCCCCHHCCCEECCCCCEEEEEEEEEEEEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCC
NNPQHGLPYSAVIKPWLGIFGAPCLAPPWGRTQAIDLVHHRKIWERALGTTKNVGPTNAL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEE
RMPVGLPTGIFSMGGTLTTPTGLVFMGATADQAFRVLDGRNGRILYETTLDAGGNATPMT
EECCCCCCHHHHCCCEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEEEECCCCCCCCEE
YMGKDGRQYVVLAVGGHGGLKTRNGDEVVAFALPK
EECCCCCEEEEEEECCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]