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The map label for this gene is dhaL [C]

Identifier: 162146095

GI number: 162146095

Start: 275283

End: 275888

Strand: Direct

Name: dhaL [C]

Synonym: GDI_0264

Alternate gene names: 162146095

Gene position: 275283-275888 (Clockwise)

Preceding gene: 162146094

Following gene: 162146096

Centisome position: 6.98

GC content: 75.25

Gene sequence:

>606_bases
TTGTTGTGCGTCTGGCTGCGCCGGGCGGCACAGGTCATCGACGACCGGCAGGACAGCCTGTCGGTGCTGGACGCCGTGAT
CGGCGACGGCGACCACGGGGCGAACATGGCGCGCGGCTTCCGGGCCGTGGCGGGCAAGCTGGACGAACCGCCCCCCGACG
TCGCCGCCCTGTTGAAGCTGGTCGGCATGACGCTGATCAGCACCGTGGGCGGTGCGTCGGGGCCGCTGTACGGCACGTTC
TTCCTGGACATGGGCAAGGCGGCCCGGGACGTCTCCGCCCTGGACGTTCCGGCATGGCGCACGCTGCTGGCGGCCGGGGT
GGCCGGGGTCGCGGCGCGGGGCAAGGCCGTGGCGGGCGACAAGACCATGCTCGACGCCCTGATCCCGGCGGTGGCGGCCC
TGTCCGGCACCCAGTCCGGCCCCGACACGCCGCAGGCCCTCGCCCGGGCGGCCGAGGCCGCCCGGCAGGGCGCGGAGGCG
ACCATCCCGATGATCGCGCGCAAGGGGCGGGCCAGCTATCTGGGCGAGCGCTCGGCGGGGCATGAGGACCCGGGCGCCGC
GTCCTCGGCGCTTCTGCTGACGGCCCTGGCCGATACGGCGGGCTAG

Upstream 100 bases:

>100_bases
ACGGACGAGATGACCCGCTACTGGGACGCCCCGTGCGTCACGCCCGCCCTGCGCTGGGGGGCGTGAGCGCATGCCGGATG
CCCGCACGGCGGATGTCGCC

Downstream 100 bases:

>100_bases
CGATGGACGCGCCCGACATCACGGCCCCCACCGCCCTGCTGCTGGTGTCGCACAGCGCGGCGCTGGCCGAAGCGACCGAG
GCCCTGATCCGGCAGATGAC

Product: PTS-dependent dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLCVWLRRAAQVIDDRQDSLSVLDAVIGDGDHGANMARGFRAVAGKLDEPPPDVAALLKLVGMTLISTVGGASGPLYGTF
FLDMGKAARDVSALDVPAWRTLLAAGVAGVAARGKAVAGDKTMLDALIPAVAALSGTQSGPDTPQALARAAEAARQGAEA
TIPMIARKGRASYLGERSAGHEDPGAASSALLLTALADTAG

Sequences:

>Translated_201_residues
MLCVWLRRAAQVIDDRQDSLSVLDAVIGDGDHGANMARGFRAVAGKLDEPPPDVAALLKLVGMTLISTVGGASGPLYGTF
FLDMGKAARDVSALDVPAWRTLLAAGVAGVAARGKAVAGDKTMLDALIPAVAALSGTQSGPDTPQALARAAEAARQGAEA
TIPMIARKGRASYLGERSAGHEDPGAASSALLLTALADTAG
>Mature_201_residues
MLCVWLRRAAQVIDDRQDSLSVLDAVIGDGDHGANMARGFRAVAGKLDEPPPDVAALLKLVGMTLISTVGGASGPLYGTF
FLDMGKAARDVSALDVPAWRTLLAAGVAGVAARGKAVAGDKTMLDALIPAVAALSGTQSGPDTPQALARAAEAARQGAEA
TIPMIARKGRASYLGERSAGHEDPGAASSALLLTALADTAG

Specific function: Unknown

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=186, Percent_Identity=37.0967741935484, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1787449, Length=195, Percent_Identity=45.6410256410256, Blast_Score=156, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6323570, Length=189, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 20271; Mature: 20271

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCVWLRRAAQVIDDRQDSLSVLDAVIGDGDHGANMARGFRAVAGKLDEPPPDVAALLKL
CHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
VGMTLISTVGGASGPLYGTFFLDMGKAARDVSALDVPAWRTLLAAGVAGVAARGKAVAGD
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCH
KTMLDALIPAVAALSGTQSGPDTPQALARAAEAARQGAEATIPMIARKGRASYLGERSAG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCC
HEDPGAASSALLLTALADTAG
CCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLCVWLRRAAQVIDDRQDSLSVLDAVIGDGDHGANMARGFRAVAGKLDEPPPDVAALLKL
CHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
VGMTLISTVGGASGPLYGTFFLDMGKAARDVSALDVPAWRTLLAAGVAGVAARGKAVAGD
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCH
KTMLDALIPAVAALSGTQSGPDTPQALARAAEAARQGAEATIPMIARKGRASYLGERSAG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCCCC
HEDPGAASSALLLTALADTAG
CCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7703858 [H]