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The map label for this gene is yabF [C]

Identifier: 162146046

GI number: 162146046

Start: 231154

End: 231945

Strand: Reverse

Name: yabF [C]

Synonym: GDI_0214

Alternate gene names: 162146046

Gene position: 231945-231154 (Counterclockwise)

Preceding gene: 162146048

Following gene: 162146045

Centisome position: 5.88

GC content: 62.5

Gene sequence:

>792_bases
ATGAATGTCCTGATCGTCTTCGCCCACCCGGAAAGACACTCGCTCAACGGCGCCCTGCTCGACGTCGCCGTCGCCGAACT
GGCGGCCCAGGGACATGAGGTGCGGGTGTCGGACCTCTATGCCATGCATTGGAAGGCCGCAGTCGACAAGGACGATTTTC
CTGCCCTGTCGTCGGACGGACCGCTGAAGGTCTGGAAAGCGTCCCATGACGGGTTCGCGGCGGATGCGCTGACGCCGGAT
GTGAAGGCGGAACAGGAGAAGCTGCTGTGGGCCGATATGGTCATTCTGCAGTTCCCGTTATGGTGGTTCGCCATGCCGGC
CATTCTCAAGGGCTGGGTGGACCGCGTCTATGCCTCCGGCTTCGCCTATGGGGTGGGCGAACACAGCGACCGGCGCTGGG
GCGACCGGTATGGCGAAGGGGTCATGGCCGGCAAGCGTGCGATGCTGATGGTCACGGCCGGAGGGTGGCCGGAACATTAT
TCGGATCGCGGGATCAACGGCCCGATCGACGATCTGCTGTTCCCGATCAACCATGGAATCCTTTTCTATCCCGGTTTCAC
CGTCCTGCCGCCCTTCGTGGCCTATCGTGTCGATCGGATGGACGAGCCGAAATTCACGATTCTGGCGGACCAAGTGCGCG
AGCGGATGAAGACACTGGAGACGATCGCACCGATTCCCTACCGCAAGCAGAATGACGGCGACTACCAGATCCCGACCATG
GAACTGCTGCCGGAACTGGCACCGCCGGGTGCGCGCGGCTTCGAAGTGCATCTCGCGCCTGAACGCGACTGA

Upstream 100 bases:

>100_bases
TCCGGCACTGTCCCTTCCGCTCAGGCCATATGGGAAGACAATAGCCTATCCCCTATCCTCGGAAAGTCGCCCATTCTTTC
CGCCTGCATGAGGAAGCCCC

Downstream 100 bases:

>100_bases
CGTCGCGGGCATGACTCCATTGCCGGATCGCGACCTGTATCGTGACCAGCGTTCGAGATGCGGCTTATCCCGCCGTGGGA
CGGCTCTAGAAAGGCGCGAG

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNVLIVFAHPERHSLNGALLDVAVAELAAQGHEVRVSDLYAMHWKAAVDKDDFPALSSDGPLKVWKASHDGFAADALTPD
VKAEQEKLLWADMVILQFPLWWFAMPAILKGWVDRVYASGFAYGVGEHSDRRWGDRYGEGVMAGKRAMLMVTAGGWPEHY
SDRGINGPIDDLLFPINHGILFYPGFTVLPPFVAYRVDRMDEPKFTILADQVRERMKTLETIAPIPYRKQNDGDYQIPTM
ELLPELAPPGARGFEVHLAPERD

Sequences:

>Translated_263_residues
MNVLIVFAHPERHSLNGALLDVAVAELAAQGHEVRVSDLYAMHWKAAVDKDDFPALSSDGPLKVWKASHDGFAADALTPD
VKAEQEKLLWADMVILQFPLWWFAMPAILKGWVDRVYASGFAYGVGEHSDRRWGDRYGEGVMAGKRAMLMVTAGGWPEHY
SDRGINGPIDDLLFPINHGILFYPGFTVLPPFVAYRVDRMDEPKFTILADQVRERMKTLETIAPIPYRKQNDGDYQIPTM
ELLPELAPPGARGFEVHLAPERD
>Mature_263_residues
MNVLIVFAHPERHSLNGALLDVAVAELAAQGHEVRVSDLYAMHWKAAVDKDDFPALSSDGPLKVWKASHDGFAADALTPD
VKAEQEKLLWADMVILQFPLWWFAMPAILKGWVDRVYASGFAYGVGEHSDRRWGDRYGEGVMAGKRAMLMVTAGGWPEHY
SDRGINGPIDDLLFPINHGILFYPGFTVLPPFVAYRVDRMDEPKFTILADQVRERMKTLETIAPIPYRKQNDGDYQIPTM
ELLPELAPPGARGFEVHLAPERD

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=226, Percent_Identity=40.7079646017699, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI4505415, Length=195, Percent_Identity=41.025641025641, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI70995396, Length=129, Percent_Identity=43.4108527131783, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1786231, Length=137, Percent_Identity=30.6569343065693, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787129, Length=222, Percent_Identity=24.7747747747748, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789406, Length=217, Percent_Identity=29.0322580645161, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 29512; Mature: 29512

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIVFAHPERHSLNGALLDVAVAELAAQGHEVRVSDLYAMHWKAAVDKDDFPALSSDG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCC
PLKVWKASHDGFAADALTPDVKAEQEKLLWADMVILQFPLWWFAMPAILKGWVDRVYASG
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FAYGVGEHSDRRWGDRYGEGVMAGKRAMLMVTAGGWPEHYSDRGINGPIDDLLFPINHGI
CEECCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCE
LFYPGFTVLPPFVAYRVDRMDEPKFTILADQVRERMKTLETIAPIPYRKQNDGDYQIPTM
EEECCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEECCHH
ELLPELAPPGARGFEVHLAPERD
HHHHHHCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MNVLIVFAHPERHSLNGALLDVAVAELAAQGHEVRVSDLYAMHWKAAVDKDDFPALSSDG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCC
PLKVWKASHDGFAADALTPDVKAEQEKLLWADMVILQFPLWWFAMPAILKGWVDRVYASG
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FAYGVGEHSDRRWGDRYGEGVMAGKRAMLMVTAGGWPEHYSDRGINGPIDDLLFPINHGI
CEECCCCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCE
LFYPGFTVLPPFVAYRVDRMDEPKFTILADQVRERMKTLETIAPIPYRKQNDGDYQIPTM
EEECCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEECCHH
ELLPELAPPGARGFEVHLAPERD
HHHHHHCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]