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The map label for this gene is fabF2 [H]

Identifier: 161870548

GI number: 161870548

Start: 1643132

End: 1644166

Strand: Direct

Name: fabF2 [H]

Synonym: NMCC_1613

Alternate gene names: 161870548

Gene position: 1643132-1644166 (Clockwise)

Preceding gene: 161870547

Following gene: 161870549

Centisome position: 76.3

GC content: 60.68

Gene sequence:

>1035_bases
ATGGGGCGCGTGTCGTACCTGTGCGTCGATGCGGCGGAGCAGGCGCTGGCGGATGCCGGTTTGCTCGGGGACGAAAGCAT
TACCGACGGACGGATGGGCGTTGCCTGCGGCTCTTCCAGCGGCAGCACCAAAGACATCGGCGATGTGGGCGAATTGTTGC
TGACCGGCACGTCGCGCAACTTCAGTGCCAACACCTATGTGCGTATGATGCCGTACACCGCCGCCGCCAATATCGGCATC
TTTTTCGGGCTGAAAGGACGCATCATCCCGACATCGAGCGCGTGTTCGTCCGGCAGCCAAGGCATAGGTTATGCCTACGA
AGCCATCAAATACGGTCTGACCGATATGATGCTGGCGGGCGGAGGCGAAGAATTTTTCCCGTCCGAAGTGTATGTTTTCG
ACTCGCTTTATGCCGCCAGCCGCCGCAACGGCGAACCGGAAAAAACCCCGCGCCCATACGACGCGAACCGCGACGGGCTG
GTCATCGGCGAAGGCGCGGGGATTTTCGTGCTGGAAGAATTGGAACACGCCAAACGGCGCGGTGCGATAATTTACGCCGA
ACTCGTCGGCTACGGAGCCAACAGCGATGCCTACCATATTTCCACGCCCCGCCCCGACGCGCAAGGCGCAATCCTTGCCT
TTCAGACGGCATTGCAACACGCAGGTCTTGCGCCCGAAGACATCGGCTGGATTAATCTGCACGGCACCGGGACGCACCAC
AACGACAGTATGGAAAGCCGTGCCGTTGCAGCGGTTTTCGGCAACAATACGCCCTGCACGTCCACCAAGCCGCAAACCGG
ACACACGCTGGGTGCGGCGGGCGCAATCGAAGCCGCGTTCGCGTGGGGCATTGCCGACCGGCAAAGCAATCCCGAAGGAA
AACTTCCGCCCCAGCTTTGGGACGGGCAGAACGATCCGAACCTTCCCGCCATCAACCTGACCGGCAGCGGCAGCCGCTGG
GAAACCGAAAAACGCATTACCGCCAGCTCGTCGTTTGCCTTCGGAGGAAGCAACTGCGTCTTAATCATCGGATGA

Upstream 100 bases:

>100_bases
GGATTGGCACGAACGTTTCCCCGAATTGGAAGCGCAACTGGGTGCGCCGATTGAAAATTACGCGCCGCCGAAACATTGGA
CGCGCAAGCAGCTCAGAAGT

Downstream 100 bases:

>100_bases
AATAAGTTTGTCAATCCCACCGCTATGCTATACAATACGCGCCTACTCTTGACGGGTCTGTAGCTCAGGGGTTAGAGCAG
GGGACTCATAATCCCTTGGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGRVSYLCVDAAEQALADAGLLGDESITDGRMGVACGSSSGSTKDIGDVGELLLTGTSRNFSANTYVRMMPYTAAANIGI
FFGLKGRIIPTSSACSSGSQGIGYAYEAIKYGLTDMMLAGGGEEFFPSEVYVFDSLYAASRRNGEPEKTPRPYDANRDGL
VIGEGAGIFVLEELEHAKRRGAIIYAELVGYGANSDAYHISTPRPDAQGAILAFQTALQHAGLAPEDIGWINLHGTGTHH
NDSMESRAVAAVFGNNTPCTSTKPQTGHTLGAAGAIEAAFAWGIADRQSNPEGKLPPQLWDGQNDPNLPAINLTGSGSRW
ETEKRITASSSFAFGGSNCVLIIG

Sequences:

>Translated_344_residues
MGRVSYLCVDAAEQALADAGLLGDESITDGRMGVACGSSSGSTKDIGDVGELLLTGTSRNFSANTYVRMMPYTAAANIGI
FFGLKGRIIPTSSACSSGSQGIGYAYEAIKYGLTDMMLAGGGEEFFPSEVYVFDSLYAASRRNGEPEKTPRPYDANRDGL
VIGEGAGIFVLEELEHAKRRGAIIYAELVGYGANSDAYHISTPRPDAQGAILAFQTALQHAGLAPEDIGWINLHGTGTHH
NDSMESRAVAAVFGNNTPCTSTKPQTGHTLGAAGAIEAAFAWGIADRQSNPEGKLPPQLWDGQNDPNLPAINLTGSGSRW
ETEKRITASSSFAFGGSNCVLIIG
>Mature_343_residues
GRVSYLCVDAAEQALADAGLLGDESITDGRMGVACGSSSGSTKDIGDVGELLLTGTSRNFSANTYVRMMPYTAAANIGIF
FGLKGRIIPTSSACSSGSQGIGYAYEAIKYGLTDMMLAGGGEEFFPSEVYVFDSLYAASRRNGEPEKTPRPYDANRDGLV
IGEGAGIFVLEELEHAKRRGAIIYAELVGYGANSDAYHISTPRPDAQGAILAFQTALQHAGLAPEDIGWINLHGTGTHHN
DSMESRAVAAVFGNNTPCTSTKPQTGHTLGAAGAIEAAFAWGIADRQSNPEGKLPPQLWDGQNDPNLPAINLTGSGSRWE
TEKRITASSSFAFGGSNCVLIIG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=356, Percent_Identity=35.9550561797753, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI223972627, Length=157, Percent_Identity=39.4904458598726, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI41872631, Length=349, Percent_Identity=26.9340974212034, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787337, Length=287, Percent_Identity=41.1149825783972, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788663, Length=335, Percent_Identity=37.0149253731343, Blast_Score=169, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71983541, Length=349, Percent_Identity=34.9570200573066, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=37.9699248120301, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI212642053, Length=359, Percent_Identity=27.0194986072423, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17550940, Length=354, Percent_Identity=25.1412429378531, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=359, Percent_Identity=33.983286908078, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24644341, Length=354, Percent_Identity=37.8531073446328, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI19920632, Length=363, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221330659, Length=363, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581345, Length=355, Percent_Identity=23.6619718309859, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 36084; Mature: 35953

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVSYLCVDAAEQALADAGLLGDESITDGRMGVACGSSSGSTKDIGDVGELLLTGTSRN
CCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHEEEECCCCC
FSANTYVRMMPYTAAANIGIFFGLKGRIIPTSSACSSGSQGIGYAYEAIKYGLTDMMLAG
CCCCEEEEEECCHHCCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHCCHHEEEEC
GGEEFFPSEVYVFDSLYAASRRNGEPEKTPRPYDANRDGLVIGEGAGIFVLEELEHAKRR
CCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHC
GAIIYAELVGYGANSDAYHISTPRPDAQGAILAFQTALQHAGLAPEDIGWINLHGTGTHH
CCEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
NDSMESRAVAAVFGNNTPCTSTKPQTGHTLGAAGAIEAAFAWGIADRQSNPEGKLPPQLW
CCCHHHCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHCCCCCCCCCCCHHHC
DGQNDPNLPAINLTGSGSRWETEKRITASSSFAFGGSNCVLIIG
CCCCCCCCCEEEECCCCCCCCCCCEEEECCCEEECCCCEEEEEC
>Mature Secondary Structure 
GRVSYLCVDAAEQALADAGLLGDESITDGRMGVACGSSSGSTKDIGDVGELLLTGTSRN
CCEEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHEEEECCCCC
FSANTYVRMMPYTAAANIGIFFGLKGRIIPTSSACSSGSQGIGYAYEAIKYGLTDMMLAG
CCCCEEEEEECCHHCCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHCCHHEEEEC
GGEEFFPSEVYVFDSLYAASRRNGEPEKTPRPYDANRDGLVIGEGAGIFVLEELEHAKRR
CCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHC
GAIIYAELVGYGANSDAYHISTPRPDAQGAILAFQTALQHAGLAPEDIGWINLHGTGTHH
CCEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
NDSMESRAVAAVFGNNTPCTSTKPQTGHTLGAAGAIEAAFAWGIADRQSNPEGKLPPQLW
CCCHHHCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHCCCCCCCCCCCHHHC
DGQNDPNLPAINLTGSGSRWETEKRITASSSFAFGGSNCVLIIG
CCCCCCCCCEEEECCCCCCCCCCCEEEECCCEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]