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The map label for this gene is serC [H]

Identifier: 161870484

GI number: 161870484

Start: 1568353

End: 1569633

Strand: Reverse

Name: serC [H]

Synonym: NMCC_1540

Alternate gene names: 161870484

Gene position: 1569633-1568353 (Counterclockwise)

Preceding gene: 161870488

Following gene: 161870483

Centisome position: 72.89

GC content: 52.07

Gene sequence:

>1281_bases
ATGTATCTATTTGTCGCTAGCATGATTTTTATATTTGTAAATCAATATATTGATGTTGTTTCCCGTGTTCGGGCGGCATG
GAATCGGGCGGAGGACAGGTATTTCCCATCCTTGCACAAAGCCTGCTGCAAGCCTAAAATCGGGCGGGTTATTGTTCAGA
ATCAAGGCTGCATTATGTCTCTTTATCCGATTTACAATTTTTCCGCCGGCCCTGCCGTATTGCCCGAAGCCGTGTTGGAA
ACGGCGCGGCAGGAAATGTTGGACTACAACGGTACGGGTTTTCCTGTGATGGCGATGAGCCACCGTTCGGAAATGTTTTT
GAGCATCCTGCATCATGCGGAACAGGATTTGAGGCAGCTTTTGAAAGTGCCTGACAACTATAAGATATTGTTTCTGCAGG
GTGGAGCAACAACCCAATTTAATATGGCAGCCATGAATCTGGCACACGGTTTCCGCACTGCCGACGCGGTGGTAACGGGC
AACTGGAGCCGTATCGCTTATGAACAGATGAGCCGTTTGACCGATACGGAAATCCGTTTGGCGGCGCATGGCGGCGAGCA
GTTCGACTATCTCGACCTGCCGCCTGTGGAAACGTGGGATGTTGCACCCGATTCGGCGTTTGTCCATTTTGCCGTCAATG
AAACGGTCAACGGGCTGCAATACCGTGAAGTGCCGCGCCTTTCAGAAGGCATGCCGCCGCTGGTGTGCGATATGTCCAGC
GAGATTTTGTCGCGCGAGTTTGATGTTGCCGACTACGGACTGATTTACGCAGGCGCACAGAAAAACATCGGGCCGGCAGG
GGTTACGGTGGTGATTGTGCGTGAGGATTTGCTCGAGCGTTGTCCGAACGATATTCCCGATGTGTTCAACTACCGTTCGC
ATTTGAACCGCGAAGGTATGTACAACACGCCGTCAACTTACGCGATTTATATGTCGGGGCTGGTGTTCCGCTGGCTGCAG
GCGCAGGGCGGTGTGAAAAAAATTGAAGCGGTCAATCGGCTGAAGGCGCAAACCTTGTATGAGACGATAGACGGCAGCGG
CGGTTTCTATATCAACCGTATCCGTCCGAATGCGCGTTCTAAAATGAATGTCGTGTTCCAAACGGGGGATGAGGAGCTTG
ACCGCCGTTTTGTGCTGGAAGCCGAATTGCAGGGCTTGTGCCTGCTTAAGGGCTATAAAACCGTCGGCGGTATGCGTGCC
AGCATTTATAATGCGATGCCGCTTGAAGGCGTGCGGGCTTTGGCAGATTTTATGCGCGATTTCCAACGGCGTTACGGTTG
A

Upstream 100 bases:

>100_bases
AGAAATGAAAGTGTTGATTTATTTTGTGTTTTTGGGACGGAAAAAAGCGGGTGTAAGGGAGGTTTGTAATGGGAAATCGT
GAATATTGTTGACAAAACAA

Downstream 100 bases:

>100_bases
TGTCCCGATGTTGTCTGAAGCGGCTTCAGACGGCATCGGCTGTTTCGGCGTTCTCCGGCGGCGTTTTGGGATGCGGGGTA
AAACTGTGCTGCCGGCGGCT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MYLFVASMIFIFVNQYIDVVSRVRAAWNRAEDRYFPSLHKACCKPKIGRVIVQNQGCIMSLYPIYNFSAGPAVLPEAVLE
TARQEMLDYNGTGFPVMAMSHRSEMFLSILHHAEQDLRQLLKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTG
NWSRIAYEQMSRLTDTEIRLAAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNGLQYREVPRLSEGMPPLVCDMSS
EILSREFDVADYGLIYAGAQKNIGPAGVTVVIVREDLLERCPNDIPDVFNYRSHLNREGMYNTPSTYAIYMSGLVFRWLQ
AQGGVKKIEAVNRLKAQTLYETIDGSGGFYINRIRPNARSKMNVVFQTGDEELDRRFVLEAELQGLCLLKGYKTVGGMRA
SIYNAMPLEGVRALADFMRDFQRRYG

Sequences:

>Translated_426_residues
MYLFVASMIFIFVNQYIDVVSRVRAAWNRAEDRYFPSLHKACCKPKIGRVIVQNQGCIMSLYPIYNFSAGPAVLPEAVLE
TARQEMLDYNGTGFPVMAMSHRSEMFLSILHHAEQDLRQLLKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTG
NWSRIAYEQMSRLTDTEIRLAAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNGLQYREVPRLSEGMPPLVCDMSS
EILSREFDVADYGLIYAGAQKNIGPAGVTVVIVREDLLERCPNDIPDVFNYRSHLNREGMYNTPSTYAIYMSGLVFRWLQ
AQGGVKKIEAVNRLKAQTLYETIDGSGGFYINRIRPNARSKMNVVFQTGDEELDRRFVLEAELQGLCLLKGYKTVGGMRA
SIYNAMPLEGVRALADFMRDFQRRYG
>Mature_426_residues
MYLFVASMIFIFVNQYIDVVSRVRAAWNRAEDRYFPSLHKACCKPKIGRVIVQNQGCIMSLYPIYNFSAGPAVLPEAVLE
TARQEMLDYNGTGFPVMAMSHRSEMFLSILHHAEQDLRQLLKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTG
NWSRIAYEQMSRLTDTEIRLAAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNGLQYREVPRLSEGMPPLVCDMSS
EILSREFDVADYGLIYAGAQKNIGPAGVTVVIVREDLLERCPNDIPDVFNYRSHLNREGMYNTPSTYAIYMSGLVFRWLQ
AQGGVKKIEAVNRLKAQTLYETIDGSGGFYINRIRPNARSKMNVVFQTGDEELDRRFVLEAELQGLCLLKGYKTVGGMRA
SIYNAMPLEGVRALADFMRDFQRRYG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=364, Percent_Identity=43.6813186813187, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=39.7222222222222, Blast_Score=273, Evalue=3e-73,
Organism=Escherichia coli, GI1787136, Length=367, Percent_Identity=46.5940054495913, Blast_Score=326, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=38.1868131868132, Blast_Score=276, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6324758, Length=384, Percent_Identity=36.1979166666667, Blast_Score=245, Evalue=1e-65,
Organism=Drosophila melanogaster, GI21356589, Length=365, Percent_Identity=43.013698630137, Blast_Score=311, Evalue=8e-85,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 48152; Mature: 48152

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLFVASMIFIFVNQYIDVVSRVRAAWNRAEDRYFPSLHKACCKPKIGRVIVQNQGCIMS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCEEE
LYPIYNFSAGPAVLPEAVLETARQEMLDYNGTGFPVMAMSHRSEMFLSILHHAEQDLRQL
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
LKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTGNWSRIAYEQMSRLTDTEIRL
HHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCEEEE
AAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNGLQYREVPRLSEGMPPLVCDMSS
EECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHCCCCHHCCCCCEEECCHH
EILSREFDVADYGLIYAGAQKNIGPAGVTVVIVREDLLERCPNDIPDVFNYRSHLNREGM
HHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHCCCCCC
YNTPSTYAIYMSGLVFRWLQAQGGVKKIEAVNRLKAQTLYETIDGSGGFYINRIRPNARS
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
KMNVVFQTGDEELDRRFVLEAELQGLCLLKGYKTVGGMRASIYNAMPLEGVRALADFMRD
CEEEEEECCCHHHHHHEEEHHHCCCEEEEECHHHHCCHHHHHHCCCCHHHHHHHHHHHHH
FQRRYG
HHHHCC
>Mature Secondary Structure
MYLFVASMIFIFVNQYIDVVSRVRAAWNRAEDRYFPSLHKACCKPKIGRVIVQNQGCIMS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCEEE
LYPIYNFSAGPAVLPEAVLETARQEMLDYNGTGFPVMAMSHRSEMFLSILHHAEQDLRQL
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
LKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTGNWSRIAYEQMSRLTDTEIRL
HHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCEEEE
AAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNGLQYREVPRLSEGMPPLVCDMSS
EECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHCCCCHHCCCCCEEECCHH
EILSREFDVADYGLIYAGAQKNIGPAGVTVVIVREDLLERCPNDIPDVFNYRSHLNREGM
HHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEEEHHHHHHCCCCCHHHHHHHHHCCCCCC
YNTPSTYAIYMSGLVFRWLQAQGGVKKIEAVNRLKAQTLYETIDGSGGFYINRIRPNARS
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
KMNVVFQTGDEELDRRFVLEAELQGLCLLKGYKTVGGMRASIYNAMPLEGVRALADFMRD
CEEEEEECCCHHHHHHEEEHHHCCCEEEEECHHHHCCHHHHHHCCCCHHHHHHHHHHHHH
FQRRYG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA