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The map label for this gene is pilE1 [H]

Identifier: 161870478

GI number: 161870478

Start: 1562786

End: 1563220

Strand: Direct

Name: pilE1 [H]

Synonym: NMCC_1534

Alternate gene names: 161870478

Gene position: 1562786-1563220 (Clockwise)

Preceding gene: 161870477

Following gene: 161870479

Centisome position: 72.57

GC content: 54.25

Gene sequence:

>435_bases
TTGGCCGAAGGTCAAAAATCAGCCGTCACAGAGTATTACCTGAATCACGGCAAATGGCCCGGCGACAACAGTTCTGCCGG
CGTGGCAACCTCCACCGACATCAAAGGCAAATATGTTCAAAGCGTTGAAGTCAAAAACGGCGTCATTACCGCCACAATGC
TTTCAAGCGGCGTAAACAACGAAATCAAAGGCAAAAAACTCTCCCTGTGGGCCAAGCGTCAAAACGGTTCGGTAAAATGG
TTCTGCGGACAGCCGGTTACGCGCGCCGACGCCAACGGCGCCAACAACGACGAAGTCAAAGCCGCCACCGGCACCACCGG
CACCACCGGCACCACCGGCAACATCGACACCAAGCACCTGCCGTCAACCTGCCGCGACGCAGCATCTGTCGTTTGCATAG
AAACACCACCTACGGCTTTCTATAAAAATACCTAA

Upstream 100 bases:

>100_bases
AAGAAAATCGACACCAAACTAGAGAAACCTTTTTACCCGATAAGTTTCCGTACCGACGAGGCTGGATTCCCGCCTGCGCG
GGAATGACGAAGCTATCCTT

Downstream 100 bases:

>100_bases
ACCGTCATTCCCACGAAAGTGGGAATCCAGAACGCAAAATCTCAAGAAACCGTTTTCCCGATAAGTTTCCGTACCGACAG
ACCTAGATTCCCGCCTGCGC

Product: pilS cassette

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MAEGQKSAVTEYYLNHGKWPGDNSSAGVATSTDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWAKRQNGSVKW
FCGQPVTRADANGANNDEVKAATGTTGTTGTTGNIDTKHLPSTCRDAASVVCIETPPTAFYKNT

Sequences:

>Translated_144_residues
MAEGQKSAVTEYYLNHGKWPGDNSSAGVATSTDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWAKRQNGSVKW
FCGQPVTRADANGANNDEVKAATGTTGTTGTTGNIDTKHLPSTCRDAASVVCIETPPTAFYKNT
>Mature_143_residues
AEGQKSAVTEYYLNHGKWPGDNSSAGVATSTDIKGKYVQSVEVKNGVITATMLSSGVNNEIKGKKLSLWAKRQNGSVKWF
CGQPVTRADANGANNDEVKAATGTTGTTGTTGNIDTKHLPSTCRDAASVVCIETPPTAFYKNT

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 15173; Mature: 15042

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGQKSAVTEYYLNHGKWPGDNSSAGVATSTDIKGKYVQSVEVKNGVITATMLSSGVNN
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCEEEEEEECCCCCC
EIKGKKLSLWAKRQNGSVKWFCGQPVTRADANGANNDEVKAATGTTGTTGTTGNIDTKHL
CCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PSTCRDAASVVCIETPPTAFYKNT
CHHHHCCCCEEEEECCCCCEECCC
>Mature Secondary Structure 
AEGQKSAVTEYYLNHGKWPGDNSSAGVATSTDIKGKYVQSVEVKNGVITATMLSSGVNN
CCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCEEEEEEECCCCCC
EIKGKKLSLWAKRQNGSVKWFCGQPVTRADANGANNDEVKAATGTTGTTGTTGNIDTKHL
CCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PSTCRDAASVVCIETPPTAFYKNT
CHHHHCCCCEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]