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The map label for this gene is ilvC [H]

Identifier: 161870429

GI number: 161870429

Start: 1505931

End: 1506944

Strand: Reverse

Name: ilvC [H]

Synonym: NMCC_1477

Alternate gene names: 161870429

Gene position: 1506944-1505931 (Counterclockwise)

Preceding gene: 161870430

Following gene: 161870425

Centisome position: 69.98

GC content: 51.18

Gene sequence:

>1014_bases
ATGCAAGTCTATTACGATAAAGATGCCGATCTGTCCCTAATCAAAGGCAAAACCGTTGCCATCATCGGTTACGGTTCGCA
AGGTCATGCCCATGCCGCCAACCTGAAAGATTCGGGTGTAAACGTGGTGATTGGTCTGCGCCAAGGTTCTTCTTGGAAAA
AAGCCGAAGCAGCCGGTCATGTCGTCAAAACCGTTGCTGAAGCGACCAAAGAAGCCGATGTCGTTATGCTGCTGCTGCCT
GACGAAACCATGCCTGCCGTCTATCACGCCGAAGTTACAGCCAATTTGAAAGAAGGCGCAACGCTGGCATTTGCACACGG
CTTCAACGTGCACTACAACCAAATCGTTCCGCGTGCCGACTTGGACGTGATTATGGTTGCTCCCAAAGGTCCGGGTCATA
CCGTACGCAGTGAATACAAACGCGGCGGCGGCGTGCCTTCTCTGATTGCCGTTTACCAAGACAATTCCGGCAAAGCCAAA
GACATCGCCCTGTCTTATGCGGCTGCCAACGGCGGCACCAAAGGCGGTGTGATTGAAACCACTTTCCGCGAAGAAACCGA
AACCGATTTGTTCGGCGAACAAGCCGTATTGTGCGGCGGCGTGGTCGAGTTGATTAAAGCAGGTTTTGAAACCCTGACCG
AAGCCGGTTACGCGCCTGAAATGGCTTACTTCGAATGTCTGCACGAAATGAAACTGATTGTTGACCTGATTTTCGAAGGC
GGTATTGCCAATATGAACTACTCCATTTCCAACAATGCGGAGTACGGCGAATACGTTACCGGCCCTGAAGTGGTCAATGC
TTCCAGCAAAGAAGCCATGCGCAATGCCCTGAAACGCATCCAAACCGGCGAATACGCAAAAATGTTTATCCAAGAGGGTA
ATGTCAACTACGCGTCTATGACTGCCCGCCGCCGTCTGAATGCCGACCACCAAGTTGAAAAAGTCGGCGCACAACTGCGT
GCCATGATGCCTTGGATTACTGCCAACAAATTGGTTGACCAAGATAAAAACTGA

Upstream 100 bases:

>100_bases
ATGAATGAAGTTGCCGATTAAGCGGCACACTCTGTTTAACCCGTCCGAAGCCGCTCAACATTTTAAGGCTTCGACAACCA
TTTACCTTAAAGGAAATCAA

Downstream 100 bases:

>100_bases
TTGTTTTCAAACGGGACTGCCTACACATCGTGTAGGCAGTTTTTTTATAGTGGATTAACAAAAATCAGGACAAGGCGACG
AAGCCGCAGACAGTACAAAT

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLRQGSSWKKAEAAGHVVKTVAEATKEADVVMLLLP
DETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRADLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAK
DIALSYAAANGGTKGGVIETTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFEG
GIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYASMTARRRLNADHQVEKVGAQLR
AMMPWITANKLVDQDKN

Sequences:

>Translated_337_residues
MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLRQGSSWKKAEAAGHVVKTVAEATKEADVVMLLLP
DETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRADLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAK
DIALSYAAANGGTKGGVIETTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFEG
GIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYASMTARRRLNADHQVEKVGAQLR
AMMPWITANKLVDQDKN
>Mature_337_residues
MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLRQGSSWKKAEAAGHVVKTVAEATKEADVVMLLLP
DETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRADLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAK
DIALSYAAANGGTKGGVIETTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFEG
GIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYASMTARRRLNADHQVEKVGAQLR
AMMPWITANKLVDQDKN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=293, Percent_Identity=37.542662116041, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323387, Length=335, Percent_Identity=35.5223880597015, Blast_Score=149, Evalue=9e-37,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 36439; Mature: 36439

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLRQGSSWKKAEAAGH
CEEEECCCCCEEEECCCEEEEEEECCCCCCEECCCCCCCCEEEEEECCCCCCCHHHHHHH
VVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRAD
HHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCEEEEEECCCCCHHHCCCCCC
LDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAKDIALSYAAANGGTKGGVIET
CCEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCEEEE
TFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFEG
EECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
GIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYASM
CCCCEEEEECCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHH
TARRRLNADHQVEKVGAQLRAMMPWITANKLVDQDKN
HHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCC
>Mature Secondary Structure
MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLRQGSSWKKAEAAGH
CEEEECCCCCEEEECCCEEEEEEECCCCCCEECCCCCCCCEEEEEECCCCCCCHHHHHHH
VVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRAD
HHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCEEEEEECCCCCHHHCCCCCC
LDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAKDIALSYAAANGGTKGGVIET
CCEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCEEEE
TFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFEG
EECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
GIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYASM
CCCCEEEEECCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHH
TARRRLNADHQVEKVGAQLRAMMPWITANKLVDQDKN
HHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA