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The map label for this gene is yegH [H]

Identifier: 161870352

GI number: 161870352

Start: 1415364

End: 1416920

Strand: Reverse

Name: yegH [H]

Synonym: NMCC_1396

Alternate gene names: 161870352

Gene position: 1416920-1415364 (Counterclockwise)

Preceding gene: 161870353

Following gene: 161870351

Centisome position: 65.8

GC content: 54.85

Gene sequence:

>1557_bases
ATGGATTTCAGTTGGTTGGCAGAACCGCATACCTGGATAGGTTTTGCCACGCTTTTGGTGTTGGAAGTCGTATTGGGGAT
AGACAATCTTGTCTTTGTGGCGATTTTGGCAAACAAGGTCCAGCCCGCACGGCGCGACCGCGCACGGATTATCGGGCTGG
GGCTGGCAGTCGTCATCCGCATCATTATGCTTGCTTTTATGGCGCACATCATCACGCTGACCGAGCCGCTGTTCCAAATC
GGCGGCCTCGCCGTTTCCGGCAAGGACATGATTATGCTCGCGGGCGGTATTTTCCTGCTTTACAAAGCCACCACCGAACT
GCATGAACGCCTCGAAGGGCACAACCGTTTTACTGTTGCCGACAACCAAAAAAAACACGCGCCGTTTTGGGGCGTGGTCG
CGCAAATCCTGATACTGGATGCCGTGTTTTCCATCGATTCGGTCATTACTGCGGTGGCGATGGTCGATCATATCGTCGTG
GCGATGGGTGCGGTCGTCGTCGCAATGGCTGTAATGATTTCTGCCAGCAAACTCTTGACCGAATTTGTCGACAGACACCC
TACCGTCGTGATGCTCTGCCTTGGTTTTTTGTTGATGATCGGTTTCAGCCTGATTGCCGAAGCCTTCCATTTCCACATTC
CCAAAGGCTACCTCTACGCCGCCATCGGCTTCTCGATTTTAATCGAACTGTTTAACCAGATTTCCCAGCGCAACAGCCGC
AAAAACGACTACATCGGCAGCTCGTGGCGCAAACGGACTGCTGAAAATGTCTTGGGTATGATGGGCATACGCGAAAGCGT
GCTTGCCGACGCGGGCGGCGAATCCGGGGACGACGCGCATTTTGAAGAAAACGAAAAATCGATGATACGCAGCGTGCTGA
CGCTTGCCGAACGCCCGATTATGGGGGTGATGATCCCACGCCGCGACATCGAACGGCTGGACATTTCCCAAAGCCGCGAA
GAACAGTATGCCCAACTGCAAAACACGCCTTACAGCCGCCTGCTCGTTGTCGGAAAGGCGGGCGTGGACGAACCTTTGGG
CTACATCAACAAAAAAGACCTGCTGTCCCAACTGCTGGAAACAGGCGGTCTCGACATTCAGACGGCATTGCGCCAGCCGC
TCGTCCTACCCGACGGCACGACCGCCTTGGGCGCGCTCGAACTCTTCCGCCAAAGCAGCGCGGATTACGCCCTCGTCGTG
GACGAGTTCGGCGCGGTGTTGGGTATGGTAACCATGAAAGACCTGTTGGAAGCCATTGCCGGCGACTTTCCCGAAGAATT
CGAACGCGAAGAAGAACCAGCCGTTCAGGGGAATCCCGATGAAAGCCTGACGGTGGAAGGCGCGTTGGAATATGTGGAGC
TGGCATCCCAACTCAATCTGCCGCAGCAGGAGGAAGATGCCGATTTCCATACGGTTGCCGGGCTGATTATGGAAGAATTG
CAAACCATCCCCGATGTCGGTGATTTTGCCGATTTCCACGGCTGGCGGTTTGAAGTGGTCGAAAAAGAAGGGCAGCGCAT
CGAGCGGGTCAAAATCACCAAATTGCCCGAAGAATAA

Upstream 100 bases:

>100_bases
CAGCAAGCCCGCCCGCCGTTTTTTGTGCGTACCGTCTGTTCAGGCAGCTTGAGCGCTTCAGGCTGCCTTTTCGCGTTTGA
ACTTGAGGAATACGAAAATC

Downstream 100 bases:

>100_bases
GTATTCAGGATAGAAAATGAACGTTTTGATTTCCAACGACGACGGCTACCTCTCCGAAGGCATCGCCGTTTTGGCGCGCG
TTACGGCGGAATTTGCCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPARRDRARIIGLGLAVVIRIIMLAFMAHIITLTEPLFQI
GGLAVSGKDMIMLAGGIFLLYKATTELHERLEGHNRFTVADNQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVV
AMGAVVVAMAVMISASKLLTEFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYLYAAIGFSILIELFNQISQRNSR
KNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESGDDAHFEENEKSMIRSVLTLAERPIMGVMIPRRDIERLDISQSRE
EQYAQLQNTPYSRLLVVGKAGVDEPLGYINKKDLLSQLLETGGLDIQTALRQPLVLPDGTTALGALELFRQSSADYALVV
DEFGAVLGMVTMKDLLEAIAGDFPEEFEREEEPAVQGNPDESLTVEGALEYVELASQLNLPQQEEDADFHTVAGLIMEEL
QTIPDVGDFADFHGWRFEVVEKEGQRIERVKITKLPEE

Sequences:

>Translated_518_residues
MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPARRDRARIIGLGLAVVIRIIMLAFMAHIITLTEPLFQI
GGLAVSGKDMIMLAGGIFLLYKATTELHERLEGHNRFTVADNQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVV
AMGAVVVAMAVMISASKLLTEFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYLYAAIGFSILIELFNQISQRNSR
KNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESGDDAHFEENEKSMIRSVLTLAERPIMGVMIPRRDIERLDISQSRE
EQYAQLQNTPYSRLLVVGKAGVDEPLGYINKKDLLSQLLETGGLDIQTALRQPLVLPDGTTALGALELFRQSSADYALVV
DEFGAVLGMVTMKDLLEAIAGDFPEEFEREEEPAVQGNPDESLTVEGALEYVELASQLNLPQQEEDADFHTVAGLIMEEL
QTIPDVGDFADFHGWRFEVVEKEGQRIERVKITKLPEE
>Mature_518_residues
MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPARRDRARIIGLGLAVVIRIIMLAFMAHIITLTEPLFQI
GGLAVSGKDMIMLAGGIFLLYKATTELHERLEGHNRFTVADNQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVV
AMGAVVVAMAVMISASKLLTEFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYLYAAIGFSILIELFNQISQRNSR
KNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESGDDAHFEENEKSMIRSVLTLAERPIMGVMIPRRDIERLDISQSRE
EQYAQLQNTPYSRLLVVGKAGVDEPLGYINKKDLLSQLLETGGLDIQTALRQPLVLPDGTTALGALELFRQSSADYALVV
DEFGAVLGMVTMKDLLEAIAGDFPEEFEREEEPAVQGNPDESLTVEGALEYVELASQLNLPQQEEDADFHTVAGLIMEEL
QTIPDVGDFADFHGWRFEVVEKEGQRIERVKITKLPEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=277, Percent_Identity=20.2166064981949, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87082033, Length=518, Percent_Identity=45.945945945946, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1788119, Length=515, Percent_Identity=46.0194174757282, Blast_Score=413, Evalue=1e-116,
Organism=Escherichia coli, GI1789197, Length=239, Percent_Identity=43.9330543933054, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1790664, Length=235, Percent_Identity=25.531914893617, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI145693175, Length=268, Percent_Identity=25.3731343283582, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786879, Length=246, Percent_Identity=26.8292682926829, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 57346; Mature: 57346

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPARRDRARIIGLGLAVVIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IIMLAFMAHIITLTEPLFQIGGLAVSGKDMIMLAGGIFLLYKATTELHERLEGHNRFTVA
HHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEC
DNQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVVAMGAVVVAMAVMISASKLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYLYAAIGFSILIELFNQISQRNSR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESGDDAHFEENEKSMIRSVLTLAERPI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
MGVMIPRRDIERLDISQSREEQYAQLQNTPYSRLLVVGKAGVDEPLGYINKKDLLSQLLE
CEEECCCHHHHHCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCCHHHCCCHHHHHHHHHH
TGGLDIQTALRQPLVLPDGTTALGALELFRQSSADYALVVDEFGAVLGMVTMKDLLEAIA
HCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
GDFPEEFEREEEPAVQGNPDESLTVEGALEYVELASQLNLPQQEEDADFHTVAGLIMEEL
CCCCHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QTIPDVGDFADFHGWRFEVVEKEGQRIERVKITKLPEE
HHCCCCCCHHHHCCCEEEHHHHHCCHHHHEECCCCCCC
>Mature Secondary Structure
MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPARRDRARIIGLGLAVVIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IIMLAFMAHIITLTEPLFQIGGLAVSGKDMIMLAGGIFLLYKATTELHERLEGHNRFTVA
HHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEC
DNQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVVAMGAVVVAMAVMISASKLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYLYAAIGFSILIELFNQISQRNSR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESGDDAHFEENEKSMIRSVLTLAERPI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
MGVMIPRRDIERLDISQSREEQYAQLQNTPYSRLLVVGKAGVDEPLGYINKKDLLSQLLE
CEEECCCHHHHHCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCCHHHCCCHHHHHHHHHH
TGGLDIQTALRQPLVLPDGTTALGALELFRQSSADYALVVDEFGAVLGMVTMKDLLEAIA
HCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
GDFPEEFEREEEPAVQGNPDESLTVEGALEYVELASQLNLPQQEEDADFHTVAGLIMEEL
CCCCHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QTIPDVGDFADFHGWRFEVVEKEGQRIERVKITKLPEE
HHCCCCCCHHHHCCCEEEHHHHHCCHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]