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The map label for this gene is hisZ [H]

Identifier: 161869758

GI number: 161869758

Start: 784125

End: 785276

Strand: Direct

Name: hisZ [H]

Synonym: NMCC_0778

Alternate gene names: 161869758

Gene position: 784125-785276 (Clockwise)

Preceding gene: 161869756

Following gene: 161869759

Centisome position: 36.41

GC content: 59.46

Gene sequence:

>1152_bases
ATGCAGACATGGCAGCTTCCGGAACATATCGCCGACGTACTGCCCACGAACGCGCGGCAGCTTGAAAGCGCGAGGGAGCA
GTTGTTGGCACTGTTCCGCGTACACGGTTATGAACTGGTACAGCCTCCGCTGATGGAGTACGCACATTCCCTGCTGACGC
ATATCGATGCGGGGCTTTCCCTGAAAACCATTTTGGTAACGGACAGGCTCAGCGGCAGGCAGTTGGGCATACGCGCCGAC
ATCACGCCGCAGGTGGCGCGTATTGATGCCCATCTTTTATCCGCCAACCAAGGGATTAACCGGTTGTGTTATGCCGGTCC
GGTGTTGCACGCGCAGCCCGACGGTCTGCTGAATATGCGCGAACCCTTGCAGGCAGGGGCGGAAATGTACGGTTTTGCCG
ACATCCGTGGCGACATCGAGCTGATAGACCTGATGCTGAAAAGCATGAAAATTGCCGATATGGGCAAAGTGCTGCTTTCG
CTGGGGCATATCGGCATATTCCGCGCCTTGTCCGATGCGGCGCATTTGGATGCGGGGCAGTCCGCAACGCTGCTTGCCTT
GATGCAGGATAAAGATACCGGGGCGGTCGAAGCGCAGGTCAAGGCTTGGAAGCTGGACGGCATGTGGGCAAAAGCATTCT
CGCTGTTGCCGCGCCTGTACGGCGGGCGTGAAGTGTTGTCCGACGCGCGCGGACGGTTGCCGGATTTGTCGGCGGTCGGC
GGCGCGTTGGGCGAATTGCAGGCGGTGTGCGACGCATTCCCCGATTGTGAAATCCATATCGACTTGTCCGAGCTGCGTGT
CGACAATTACCACACGGGCTTGCTGTATGCCGCCTATGCCGCCGATTTCCACGACGCGGTCGCGCGCGGCGGGCGTTATG
ACGGATTGGGCGGATATTTCGGCAGGGCGCGCCCGGCAACGGGATTCAGTTTCGACTTGCGCAGCTTTATCGGGCGTTTG
CCCGCCATCGAACGGCAGCCCGCCGTGTTGGTCGATGCGGAAGATGCCGAAGCGGCGCGCGAAGCGGTCGAAGCCTTGCG
TGAACAAGGGCAGTGTGTCGTAATCGATTACGGTATCGGACACAATGTTTCGGAAGAGCTTGCAGGCCGTCTGAAAAAGA
CGGACGGCGTTTGGCAGGTCGTGAAACGCTAA

Upstream 100 bases:

>100_bases
CCGTTTTGACAGCGGCGTGATGCGTTGCGGCAAAGATGCCGTCTGATTGCGGATCGGGCAGCCTTTTGTATTTACATGAT
AAAATAGAAGGCAGATTCTC

Downstream 100 bases:

>100_bases
ATACCCGTTCATGGCGGATGAAAGGCAAATCGTGGCGGGGCGCAAAGCCGCACCGGTTTGGGGATTTCCGCAATAATTTT
TAATATCGATAGGTTATATG

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPLMEYAHSLLTHIDAGLSLKTILVTDRLSGRQLGIRAD
ITPQVARIDAHLLSANQGINRLCYAGPVLHAQPDGLLNMREPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLS
LGHIGIFRALSDAAHLDAGQSATLLALMQDKDTGAVEAQVKAWKLDGMWAKAFSLLPRLYGGREVLSDARGRLPDLSAVG
GALGELQAVCDAFPDCEIHIDLSELRVDNYHTGLLYAAYAADFHDAVARGGRYDGLGGYFGRARPATGFSFDLRSFIGRL
PAIERQPAVLVDAEDAEAAREAVEALREQGQCVVIDYGIGHNVSEELAGRLKKTDGVWQVVKR

Sequences:

>Translated_383_residues
MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPLMEYAHSLLTHIDAGLSLKTILVTDRLSGRQLGIRAD
ITPQVARIDAHLLSANQGINRLCYAGPVLHAQPDGLLNMREPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLS
LGHIGIFRALSDAAHLDAGQSATLLALMQDKDTGAVEAQVKAWKLDGMWAKAFSLLPRLYGGREVLSDARGRLPDLSAVG
GALGELQAVCDAFPDCEIHIDLSELRVDNYHTGLLYAAYAADFHDAVARGGRYDGLGGYFGRARPATGFSFDLRSFIGRL
PAIERQPAVLVDAEDAEAAREAVEALREQGQCVVIDYGIGHNVSEELAGRLKKTDGVWQVVKR
>Mature_383_residues
MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPLMEYAHSLLTHIDAGLSLKTILVTDRLSGRQLGIRAD
ITPQVARIDAHLLSANQGINRLCYAGPVLHAQPDGLLNMREPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLS
LGHIGIFRALSDAAHLDAGQSATLLALMQDKDTGAVEAQVKAWKLDGMWAKAFSLLPRLYGGREVLSDARGRLPDLSAVG
GALGELQAVCDAFPDCEIHIDLSELRVDNYHTGLLYAAYAADFHDAVARGGRYDGLGGYFGRARPATGFSFDLRSFIGRL
PAIERQPAVLVDAEDAEAAREAVEALREQGQCVVIDYGIGHNVSEELAGRLKKTDGVWQVVKR

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41765; Mature: 41765

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPLMEYAHSLLTHIDAGLS
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCCC
LKTILVTDRLSGRQLGIRADITPQVARIDAHLLSANQGINRLCYAGPVLHAQPDGLLNMR
EEEEEEECCCCCCEECEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHH
EPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLSLGHIGIFRALSDAAHLDAGQ
HHHHHCHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SATLLALMQDKDTGAVEAQVKAWKLDGMWAKAFSLLPRLYGGREVLSDARGRLPDLSAVG
CCEEEEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
GALGELQAVCDAFPDCEIHIDLSELRVDNYHTGLLYAAYAADFHDAVARGGRYDGLGGYF
HHHHHHHHHHHCCCCCEEEEEHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRARPATGFSFDLRSFIGRLPAIERQPAVLVDAEDAEAAREAVEALREQGQCVVIDYGIG
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCC
HNVSEELAGRLKKTDGVWQVVKR
CCHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPLMEYAHSLLTHIDAGLS
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCCC
LKTILVTDRLSGRQLGIRADITPQVARIDAHLLSANQGINRLCYAGPVLHAQPDGLLNMR
EEEEEEECCCCCCEECEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHH
EPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLSLGHIGIFRALSDAAHLDAGQ
HHHHHCHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SATLLALMQDKDTGAVEAQVKAWKLDGMWAKAFSLLPRLYGGREVLSDARGRLPDLSAVG
CCEEEEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
GALGELQAVCDAFPDCEIHIDLSELRVDNYHTGLLYAAYAADFHDAVARGGRYDGLGGYF
HHHHHHHHHHHCCCCCEEEEEHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRARPATGFSFDLRSFIGRLPAIERQPAVLVDAEDAEAAREAVEALREQGQCVVIDYGIG
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCC
HNVSEELAGRLKKTDGVWQVVKR
CCHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA