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The map label for this gene is ribH [H]

Identifier: 161869624

GI number: 161869624

Start: 652014

End: 652490

Strand: Reverse

Name: ribH [H]

Synonym: NMCC_0641

Alternate gene names: 161869624

Gene position: 652490-652014 (Counterclockwise)

Preceding gene: 161869626

Following gene: 161869623

Centisome position: 30.3

GC content: 54.72

Gene sequence:

>477_bases
ATGAACACCATCGCCCCCAACCTCGACGGCAAACACCTCCGCATCGGCATCGTACAGGCACGTTTCACCAACGAAATCGG
CAGCGAAATGCTCAAAGTCTGCTGCCGCACCCTCCAAGAATTGGGCGTGGCAGACGAAAACATTACCGTCGCCACCGTAC
CCGGCGCACTTGAAATCCCCATCGCACTGATGAACTTTGCCTCTTCTGAAAAATTTGACGCACTGATTGCCATCGGCGTC
GTTATCCGTGGCGAAACCTACCATTTCGAGCTGGTTTCCAACGAATCCGGAGCAGGGGTCAGCCGCGTCGCACTCGACTA
CAACATCCCGATTGCCAATGCCGTCCTGACCACCGAAAACGACGCACAGGCAATCGAACGGATTGAAGAAAAAGCCTCGG
ATGCCGCCAAAGTCGCCGTCGAATGCGCCAACCTCGTCAACCTGCTGCTCGAAGAACAGTTTGAAGACGAAGAATAA

Upstream 100 bases:

>100_bases
TTGGCAGAAGACGGCACATTCCAAACCGTCGCCGACTGGCAACCTAAGGACTGACCCTTCAGACGGCATTCCGAAACCTC
CGAATACCAAAGGACACCCA

Downstream 100 bases:

>100_bases
CAAACAGGGCGTACACCAATACGCCCTTTCCGTTTCAGACGGCATACCGTGCCGCCCAACCGTTTCAAGGAAAAATCATG
AAAACAGCCCGCCGCCGTTC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIPIALMNFASSEKFDALIAIGV
VIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE

Sequences:

>Translated_158_residues
MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIPIALMNFASSEKFDALIAIGV
VIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE
>Mature_158_residues
MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIPIALMNFASSEKFDALIAIGV
VIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=44.3708609271523, Blast_Score=114, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324429, Length=148, Percent_Identity=31.7567567567568, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 17074; Mature: 17074

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIP
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHH
IALMNFASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTEN
HHHHHHCCCCCHHHEEEEEEEEECCEEEEEEEECCCCCCEEEEEEEECCCCCCEEEECCC
DAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIP
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHH
IALMNFASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTEN
HHHHHHCCCCCHHHEEEEEEEEECCEEEEEEEECCCCCCEEEEEEEECCCCCCEEEECCC
DAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA