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The map label for this gene is yggV [C]

Identifier: 161869572

GI number: 161869572

Start: 611615

End: 612214

Strand: Reverse

Name: yggV [C]

Synonym: NMCC_0587

Alternate gene names: 161869572

Gene position: 612214-611615 (Counterclockwise)

Preceding gene: 161869573

Following gene: 161869571

Centisome position: 28.43

GC content: 57.0

Gene sequence:

>600_bases
ATGTCTGAAAAACCGGAAAAAATCGTTTTGGCAAGCGGCAATGCCGGCAAGCTCGAAGAGTTCGGCAACTTATTCAAACC
TTACAGCATCACCGTATTGCCGCAATCCGCATTCGGCATACCCGAATGCCCCGAACCCTATCCCACCTTTGTCGAAAACG
CGCTGGCAAAAGCACGCCATGCCGCCAAATACAGCGGGCTGCCCGCACTCGCCGACGACAGCGGCATCTGTGCCGCCGCC
TTAAACGGCGCGCCGGGCATCCATTCCGCACGTTACGCGGGCGACAATCCCAAATCCGATACCGCCAACAACCTGAAACT
TGCCGCCGAACTTGTCGGCAAGGCAGACAAAAGCTGCTGCTATGTCTGCGTATTGGTTTTTGTCCGCCATAAAGACGACC
CGCGCCCGATTATCGCCGAGGGCGTATGGCACGGGCAGTGGAACGACACGCCGCTCGGGCAAAACGGTTTCGGTTACGAC
CCGTATTTTTATCTGCCCGAACACGGCAAAACCGCCGCCGAATTGGATACGGAGGTCAAAAACCGCGAAAGCCACCGCGC
GCAGGCACTTGCCGAACTCTTACGCAAACTCGCCCTTTAA

Upstream 100 bases:

>100_bases
TTCGCATTCGGCGCACTGTTCGGACAAATCGGCAGCCTCGCCCTCTACCTGCGGCACAAATCCCTACGCGCCGCCCAATC
CGCCACAAAGGAAAACCGCT

Downstream 100 bases:

>100_bases
ACATCAAAACAATACAAAGGAAAAAGAATGAAACCCATACGGAAAGCCGTTTTCCCCGTCGCAGGGATGGGAACCCGCTT
CCTGCCCGCCACCAAGGCCA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSEKPEKIVLASGNAGKLEEFGNLFKPYSITVLPQSAFGIPECPEPYPTFVENALAKARHAAKYSGLPALADDSGICAAA
LNGAPGIHSARYAGDNPKSDTANNLKLAAELVGKADKSCCYVCVLVFVRHKDDPRPIIAEGVWHGQWNDTPLGQNGFGYD
PYFYLPEHGKTAAELDTEVKNRESHRAQALAELLRKLAL

Sequences:

>Translated_199_residues
MSEKPEKIVLASGNAGKLEEFGNLFKPYSITVLPQSAFGIPECPEPYPTFVENALAKARHAAKYSGLPALADDSGICAAA
LNGAPGIHSARYAGDNPKSDTANNLKLAAELVGKADKSCCYVCVLVFVRHKDDPRPIIAEGVWHGQWNDTPLGQNGFGYD
PYFYLPEHGKTAAELDTEVKNRESHRAQALAELLRKLAL
>Mature_198_residues
SEKPEKIVLASGNAGKLEEFGNLFKPYSITVLPQSAFGIPECPEPYPTFVENALAKARHAAKYSGLPALADDSGICAAAL
NGAPGIHSARYAGDNPKSDTANNLKLAAELVGKADKSCCYVCVLVFVRHKDDPRPIIAEGVWHGQWNDTPLGQNGFGYDP
YFYLPEHGKTAAELDTEVKNRESHRAQALAELLRKLAL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=194, Percent_Identity=45.8762886597938, Blast_Score=177, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17556833, Length=190, Percent_Identity=31.0526315789474, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920712, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21508; Mature: 21377

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKPEKIVLASGNAGKLEEFGNLFKPYSITVLPQSAFGIPECPEPYPTFVENALAKARH
CCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
AAKYSGLPALADDSGICAAALNGAPGIHSARYAGDNPKSDTANNLKLAAELVGKADKSCC
HHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHH
YVCVLVFVRHKDDPRPIIAEGVWHGQWNDTPLGQNGFGYDPYFYLPEHGKTAAELDTEVK
HHHHHHHHHCCCCCCCEEECCEECCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
NRESHRAQALAELLRKLAL
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEKPEKIVLASGNAGKLEEFGNLFKPYSITVLPQSAFGIPECPEPYPTFVENALAKARH
CCCCCEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
AAKYSGLPALADDSGICAAALNGAPGIHSARYAGDNPKSDTANNLKLAAELVGKADKSCC
HHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHH
YVCVLVFVRHKDDPRPIIAEGVWHGQWNDTPLGQNGFGYDPYFYLPEHGKTAAELDTEVK
HHHHHHHHHCCCCCCCEEECCEECCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
NRESHRAQALAELLRKLAL
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]