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The map label for this gene is galU [H]

Identifier: 161869571

GI number: 161869571

Start: 610718

End: 611587

Strand: Reverse

Name: galU [H]

Synonym: NMCC_0586

Alternate gene names: 161869571

Gene position: 611587-610718 (Counterclockwise)

Preceding gene: 161869572

Following gene: 161869570

Centisome position: 28.4

GC content: 57.01

Gene sequence:

>870_bases
ATGAAACCCATACGGAAAGCCGTTTTCCCCGTCGCAGGGATGGGAACCCGCTTCCTGCCCGCCACCAAGGCCAGCCCGAA
AGAAATGCTGCCCATCGTCGACAAGCCGCTGATCCAATACGCCGTAGAAGAAGCCGTGGAAGCCGGCTGCACGGAAATGG
TGTTTGTTACCGGACGCAACAAACGCAGCATCGAAGACCATTTCGACAAGGCATACGAACTCGAAACCGAGTTGGAAATG
CGCCATAAAGACAAATTGTTGGAACACGTCCGCAACATCCTGCCGCCGAACATTACCTGCCTCTACATCCGTCAGGCGGA
AGCACTGGGCTTGGGACACGCCGTCTTGTGCGCCCGCGCCGCCATCGGAGACGAACCCTTTGCCGTTATCCTTGCCGACG
ACCTGATTGATGCCCCCAAAGGCGCGCTCAAACAAATGGTCGAAGTGTACGGGCGCAGCGGCAACAGCATTTTGGGCGTA
GAAACCGTTGAAGCATCGCAAACCGGCTCATACGGCATCGTCGAAACCGAACAGCTCAAACAGTTCCAACGCATTACCGG
CATTGTCGAAAAACCCAAGCCCGAAGACGCGCCCTCCAACCTTGCCGTTGTTGGACGCTACATCCTCACCCCGCGCATTT
TCGACCTCTTAACCAATCTTCCGCGCGGCGCGGGCAACGAAATCCAGCTTACAGACGGCATCGCCAAGCTGCTCGATCAC
GAATTTGTCCTGGCGCACCCCTTTGAAGGTACGCGCTACGACTGCGGCAGCAAACTGGGCTACCTCGAAGCCACCGTCGC
CTACGGTCTGAAACATCCCGAAACCGGCGAACCCTTCCGCCGGCTTTTGGAAAAATACCGCACCGAATAA

Upstream 100 bases:

>100_bases
TACGGAGGTCAAAAACCGCGAAAGCCACCGCGCGCAGGCACTTGCCGAACTCTTACGCAAACTCGCCCTTTAAACATCAA
AACAATACAAAGGAAAAAGA

Downstream 100 bases:

>100_bases
CCCCATCAAGGAATCCTTATGCACGACAAAACCTGGTCCGGACGTTTCAACGAACCCGTTTCCGAACTCGTCAAACAATA
CACCGCCTCCATCGGTTTCG

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKPIRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRNKRSIEDHFDKAYELETELEM
RHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARAAIGDEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGV
ETVEASQTGSYGIVETEQLKQFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGNEIQLTDGIAKLLDH
EFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETGEPFRRLLEKYRTE

Sequences:

>Translated_289_residues
MKPIRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRNKRSIEDHFDKAYELETELEM
RHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARAAIGDEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGV
ETVEASQTGSYGIVETEQLKQFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGNEIQLTDGIAKLLDH
EFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETGEPFRRLLEKYRTE
>Mature_289_residues
MKPIRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRNKRSIEDHFDKAYELETELEM
RHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARAAIGDEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGV
ETVEASQTGSYGIVETEQLKQFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGNEIQLTDGIAKLLDH
EFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETGEPFRRLLEKYRTE

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipote

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=291, Percent_Identity=49.8281786941581, Blast_Score=280, Evalue=5e-77,
Organism=Escherichia coli, GI1788355, Length=294, Percent_Identity=44.2176870748299, Blast_Score=240, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI133931050, Length=225, Percent_Identity=28.8888888888889, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355443, Length=267, Percent_Identity=23.5955056179775, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644084, Length=267, Percent_Identity=23.5955056179775, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32030; Mature: 32030

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRN
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KRSIEDHFDKAYELETELEMRHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCHHHHHHHHH
AIGDEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGVETVEASQTGSYGIVETEQLK
HCCCCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEHHHHH
QFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGNEIQLTDGIAKLLDH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCC
EFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETGEPFRRLLEKYRTE
CEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKPIRKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVEAGCTEMVFVTGRN
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KRSIEDHFDKAYELETELEMRHKDKLLEHVRNILPPNITCLYIRQAEALGLGHAVLCARA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCHHHHHHHHH
AIGDEPFAVILADDLIDAPKGALKQMVEVYGRSGNSILGVETVEASQTGSYGIVETEQLK
HCCCCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEHHHHH
QFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGNEIQLTDGIAKLLDH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCC
EFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETGEPFRRLLEKYRTE
CEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA