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The map label for this gene is etfD [H]

Identifier: 161869513

GI number: 161869513

Start: 547407

End: 549068

Strand: Reverse

Name: etfD [H]

Synonym: NMCC_0527

Alternate gene names: 161869513

Gene position: 549068-547407 (Counterclockwise)

Preceding gene: 161869514

Following gene: 161869506

Centisome position: 25.5

GC content: 54.57

Gene sequence:

>1662_bases
ATGACAGAATCCATCACCCGCGACAGTATGCAATACGATGTCGTGATTGTCGGCGCAGGCCCGTCGGGTTTGTCCGCCGC
CATCAAACTCAAGCAGCTTGCCGAAAAAAACGGGCGCGAAATCAGCGTTTGCGTGGTGGAGAAAGGTTCTGAAGCAGGCG
CGCATTCGCTGGCGGGCGCGGTCATTGACCCGATTGCGCTGAATGAGTTGATTCCCGACTGGAAAGAAAAAGGCGCGCCG
CTGACGCGCACGGTAACGCAGGACAAGGTGTTGTTCCTGACTGAGAAAAAAGCGTTCAATCTGCCTATTACCCCAAATTT
CGACAATCACGGCAACTACATCGTCAGCTTGGGCGAAGTCGTGCGCTGGTTGGCGGAGCAGGCGGAAAATTTGGGCGTGG
AAATTTATCCGGGCTTTGCCGCCGCCGAAGTGCTGTATCACGAAGACGGTTCGGTCAAAGGCATTGCGACCGGCAATATG
GGCATTGGCAAAGACGGCGAGCCGACCGACAGTTTCCAGCCCGGCATGGAGCTTTGGGCGCAGCAAACTCTGTTTGCCGA
AGGTTGTCGCGGTTCGCTTTCCAAACAAGTCATCGAACGTTTCCAACTCGACCAAAACAGCCAGCCGCAAACTTACGGCT
TGGGCATCAAAGAAATTTGGGAAGTGCCGTCTGAAAAACATCAGCCCGGCTTGGTGGTGCACAGCGCGGGCTGGCCGCTG
GACAGCAAAACCTACGGCGGCGCGTTTGTTTACCATTTCGATGACAACAAAGTCGCCGTCGGTTTCGTGGTCGGTTTGGA
CTATCAAAACCCTTATCTGTCGCCGTTTGAAGAGTTCCAACGTTTCAAAACCCATCCCGAAATCCGCAAAACCTTTGAAG
GCGGCCGCCGCATCGCTTACGGCGCGCGTTCGCTGATTGAAGGCGGTTTGCAAAGTTTGCCGAAGCTCTCGTTCAAAGGC
GGCGTTTTAATCGGCGACGCGGCAGGCTTCCTCAATATGCCGCGCATCAAAGGCATTCATACCGCGATGAAATCCGCCAT
GCTCGCCGCAGAAGCCGTGTTCCCCTTGTTGGAAAACCTTGAAGAAGTGGAAAACTTCGACAGCGGCAAAGAGGCGGCGG
ATTATCAGCAACGTTTTGAACAAAGCTGGCTGTATCAAGAGCTTTACGCCGCGCGCAATGTCCGTCCGTCATTCAAATGG
GGCGTTTACCTCGGCTCAATCTACACCGGCATCGATCAGATGATTTTCAGAGGCAAAGCCCCGTGGACCTTGAAACATCA
CGGCAAAGACAACGAGCAGCTCAAAAAAGCCGCCGCGTGCAAGCCGATTGATTATCCGAAACCCGACGGCGTGTTGACCT
TCGACCGCTTGAGCAGCGTCTTCCTTGCCAATCTCGCGCACGAAGAAAACCAGCCCGACCATTTGGTGCTGAACAATCCG
CAAACGATGATAGACGTGAACTACAAAGAATACGCCTCGCCCGAAACGCGCTATTGTCCGGCCGGCGTGTACGAAATTGT
TGAAGAAAACGGCAATCCGCGCCTGCAAATCAACGCGGCAAACTGCGTGCACTGCAAAACCTGCGACATCAAAGACCCGA
CGCAAAACATCACTTGGATTTGCCCCGAAAGCGCGAGCGGGCCGAATTACGGCGGGATGTAA

Upstream 100 bases:

>100_bases
AAATATGGTTTTCAGACGACCTTTGTTGTATTTGGTAACTATATGTTCCCGTTGTATAATTACGGATTTGCAATTCAATA
ATAAATACACAGGAACCGCC

Downstream 100 bases:

>100_bases
ACCTTATTCCGCCGTTACGCCCGGTCAGGAATAAGGAATGGGGCAGTTGTTCAAACCTGCCCCGTTTGAACCTATGACAA
AAAATGCCGTCTGAACCTTG

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEKNGREISVCVVEKGSEAGAHSLAGAVIDPIALNELIPDWKEKGAP
LTRTVTQDKVLFLTEKKAFNLPITPNFDNHGNYIVSLGEVVRWLAEQAENLGVEIYPGFAAAEVLYHEDGSVKGIATGNM
GIGKDGEPTDSFQPGMELWAQQTLFAEGCRGSLSKQVIERFQLDQNSQPQTYGLGIKEIWEVPSEKHQPGLVVHSAGWPL
DSKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPFEEFQRFKTHPEIRKTFEGGRRIAYGARSLIEGGLQSLPKLSFKG
GVLIGDAAGFLNMPRIKGIHTAMKSAMLAAEAVFPLLENLEEVENFDSGKEAADYQQRFEQSWLYQELYAARNVRPSFKW
GVYLGSIYTGIDQMIFRGKAPWTLKHHGKDNEQLKKAAACKPIDYPKPDGVLTFDRLSSVFLANLAHEENQPDHLVLNNP
QTMIDVNYKEYASPETRYCPAGVYEIVEENGNPRLQINAANCVHCKTCDIKDPTQNITWICPESASGPNYGGM

Sequences:

>Translated_553_residues
MTESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEKNGREISVCVVEKGSEAGAHSLAGAVIDPIALNELIPDWKEKGAP
LTRTVTQDKVLFLTEKKAFNLPITPNFDNHGNYIVSLGEVVRWLAEQAENLGVEIYPGFAAAEVLYHEDGSVKGIATGNM
GIGKDGEPTDSFQPGMELWAQQTLFAEGCRGSLSKQVIERFQLDQNSQPQTYGLGIKEIWEVPSEKHQPGLVVHSAGWPL
DSKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPFEEFQRFKTHPEIRKTFEGGRRIAYGARSLIEGGLQSLPKLSFKG
GVLIGDAAGFLNMPRIKGIHTAMKSAMLAAEAVFPLLENLEEVENFDSGKEAADYQQRFEQSWLYQELYAARNVRPSFKW
GVYLGSIYTGIDQMIFRGKAPWTLKHHGKDNEQLKKAAACKPIDYPKPDGVLTFDRLSSVFLANLAHEENQPDHLVLNNP
QTMIDVNYKEYASPETRYCPAGVYEIVEENGNPRLQINAANCVHCKTCDIKDPTQNITWICPESASGPNYGGM
>Mature_552_residues
TESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEKNGREISVCVVEKGSEAGAHSLAGAVIDPIALNELIPDWKEKGAPL
TRTVTQDKVLFLTEKKAFNLPITPNFDNHGNYIVSLGEVVRWLAEQAENLGVEIYPGFAAAEVLYHEDGSVKGIATGNMG
IGKDGEPTDSFQPGMELWAQQTLFAEGCRGSLSKQVIERFQLDQNSQPQTYGLGIKEIWEVPSEKHQPGLVVHSAGWPLD
SKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPFEEFQRFKTHPEIRKTFEGGRRIAYGARSLIEGGLQSLPKLSFKGG
VLIGDAAGFLNMPRIKGIHTAMKSAMLAAEAVFPLLENLEEVENFDSGKEAADYQQRFEQSWLYQELYAARNVRPSFKWG
VYLGSIYTGIDQMIFRGKAPWTLKHHGKDNEQLKKAAACKPIDYPKPDGVLTFDRLSSVFLANLAHEENQPDHLVLNNPQ
TMIDVNYKEYASPETRYCPAGVYEIVEENGNPRLQINAANCVHCKTCDIKDPTQNITWICPESASGPNYGGM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=558, Percent_Identity=57.168458781362, Blast_Score=657, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=398, Percent_Identity=29.6482412060301, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786227, Length=442, Percent_Identity=27.3755656108597, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87082155, Length=367, Percent_Identity=26.7029972752044, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144720, Length=560, Percent_Identity=55.7142857142857, Blast_Score=624, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6324932, Length=580, Percent_Identity=50, Blast_Score=547, Evalue=1e-156,
Organism=Drosophila melanogaster, GI24652256, Length=558, Percent_Identity=57.3476702508961, Blast_Score=656, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 61102; Mature: 60971

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEKNGREISVCVVEKGSEAGAHSLAGA
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHH
VIDPIALNELIPDWKEKGAPLTRTVTQDKVLFLTEKKAFNLPITPNFDNHGNYIVSLGEV
HHCHHHHHHHCCCHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHH
VRWLAEQAENLGVEIYPGFAAAEVLYHEDGSVKGIATGNMGIGKDGEPTDSFQPGMELWA
HHHHHHHHHHCCEEEECCHHEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
QQTLFAEGCRGSLSKQVIERFQLDQNSQPQTYGLGIKEIWEVPSEKHQPGLVVHSAGWPL
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEECCCHHHHHCCCCCCCCCCEEEECCCCCC
DSKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPFEEFQRFKTHPEIRKTFEGGRRIAY
CCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEHH
GARSLIEGGLQSLPKLSFKGGVLIGDAAGFLNMPRIKGIHTAMKSAMLAAEAVFPLLENL
HHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEVENFDSGKEAADYQQRFEQSWLYQELYAARNVRPSFKWGVYLGSIYTGIDQMIFRGKA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHCCCC
PWTLKHHGKDNEQLKKAAACKPIDYPKPDGVLTFDRLSSVFLANLAHEENQPDHLVLNNP
CEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEECCC
QTMIDVNYKEYASPETRYCPAGVYEIVEENGNPRLQINAANCVHCKTCDIKDPTQNITWI
CEEEEECHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCEEEE
CPESASGPNYGGM
CCCCCCCCCCCCC
>Mature Secondary Structure 
TESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEKNGREISVCVVEKGSEAGAHSLAGA
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHH
VIDPIALNELIPDWKEKGAPLTRTVTQDKVLFLTEKKAFNLPITPNFDNHGNYIVSLGEV
HHCHHHHHHHCCCHHHCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHH
VRWLAEQAENLGVEIYPGFAAAEVLYHEDGSVKGIATGNMGIGKDGEPTDSFQPGMELWA
HHHHHHHHHHCCEEEECCHHEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
QQTLFAEGCRGSLSKQVIERFQLDQNSQPQTYGLGIKEIWEVPSEKHQPGLVVHSAGWPL
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEECCCHHHHHCCCCCCCCCCEEEECCCCCC
DSKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPFEEFQRFKTHPEIRKTFEGGRRIAY
CCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEHH
GARSLIEGGLQSLPKLSFKGGVLIGDAAGFLNMPRIKGIHTAMKSAMLAAEAVFPLLENL
HHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEVENFDSGKEAADYQQRFEQSWLYQELYAARNVRPSFKWGVYLGSIYTGIDQMIFRGKA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHCCCC
PWTLKHHGKDNEQLKKAAACKPIDYPKPDGVLTFDRLSSVFLANLAHEENQPDHLVLNNP
CEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEECCC
QTMIDVNYKEYASPETRYCPAGVYEIVEENGNPRLQINAANCVHCKTCDIKDPTQNITWI
CEEEEECHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCCCEEEE
CPESASGPNYGGM
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]