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The map label for this gene is aroK [H]

Identifier: 161869407

GI number: 161869407

Start: 427836

End: 428348

Strand: Reverse

Name: aroK [H]

Synonym: NMCC_0415

Alternate gene names: 161869407

Gene position: 428348-427836 (Counterclockwise)

Preceding gene: 161869408

Following gene: 161869406

Centisome position: 19.89

GC content: 57.31

Gene sequence:

>513_bases
ATGAAAAACTTTAACGGCAAACTCATCCTCATCGGACTGATGGGCGCGGGCAAAACCACGCTGGGCCGGCAAATGGCGCA
GCGGCTGGATTACCGTTTTTACGACAGCGATCACGAAATCGCCGCAGCCGCCGGCGTTCCCATCCCCACCATATTTGAAA
TGGAAGGCGAACAGGGATTCCGTTCGCGCGAAACCGCCATACTCAAAAAGCTGGTTATCCTGCCCCATATCGTCCTGTCC
ACCGGCGGCGGCGCGGTGTTAAAAGAAGAAAACCGCGCCCTTATCCGCAAAAGCGGCACGGTCGTCTATCTGCACGCCCC
GCCCGAAACCCTGCTCGAACGCACGCGCTGCGACAACAGCCGTCCTTTGCTGCAAGTTGCCGATCCTTTGGCGAAATTAC
GTGAACTCTACGCCGCACGCGACCCCGTTTACCGCCAAACCGCCGACTTTACCGTAGAATCGGCAAACTGCCGGGAAACC
GTGCAAACCCTGCTCAAACGCTTATCCCGATAA

Upstream 100 bases:

>100_bases
TACCGCCGCCCTGCCGATTTCGTATAAAATTCCGCCGTAACCCGACAAGCCCGAACCCTGTCGCCCCGAAAGGCGGGGTG
TCAAACATTAAGGAATTGTG

Downstream 100 bases:

>100_bases
ACCGGCATATGCGCCGCGCCCAGAAAACCAAACCGCGCCCCGCCCGGCGGGCCGGCGGTTCAAACTTTAAGGAACAACAA
TGAAAACACTGACCGTACAC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLS
TGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRET
VQTLLKRLSR

Sequences:

>Translated_170_residues
MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLS
TGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRET
VQTLLKRLSR
>Mature_170_residues
MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLS
TGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRET
VQTLLKRLSR

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=146, Percent_Identity=45.2054794520548, Blast_Score=130, Evalue=4e-32,
Organism=Escherichia coli, GI1786587, Length=153, Percent_Identity=38.562091503268, Blast_Score=100, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=164, Percent_Identity=28.6585365853659, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18980; Mature: 18980

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGF
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCCCCEEEEECCCCCC
RSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNS
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCEEEEECCHHHHHHHHCCCCC
RPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRETVQTLLKRLSR
CCHHHHHHHHHHHHHHHHHCCCCHHCCCCCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGF
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCCCCEEEEECCCCCC
RSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNS
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCEEEEECCHHHHHHHHCCCCC
RPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRETVQTLLKRLSR
CCHHHHHHHHHHHHHHHHHCCCCHHCCCCCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA