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The map label for this gene is aroB [H]

Identifier: 161869406

GI number: 161869406

Start: 426677

End: 427756

Strand: Reverse

Name: aroB [H]

Synonym: NMCC_0414

Alternate gene names: 161869406

Gene position: 427756-426677 (Counterclockwise)

Preceding gene: 161869407

Following gene: 161869405

Centisome position: 19.86

GC content: 59.35

Gene sequence:

>1080_bases
ATGAAAACACTGACCGTACACACCCCGTCCCACAGCTACCCCATCTTTATCGGCAACGGACTGCTGCCGCAGGCAGGAAG
CCTGCTCAAACCGCATTTGGGCAAACGCGCCGCCATCATCACCAACGAAACCGTCGCCCCGCTCTACCTCGGCACGCTTC
AGACGGCATTGGATGCGGCAGGCGTATCCCATTTCAGCATCATCCTGCCCGACGGCGAGGCGCACAAAAACTGGCAGACG
CTCAACCTCATCTTTGACGGGCTGATGCAAAACCGCGCCGAACGCAAAACCACGCTCATCGCACTGGGCGGCGGCGTGAT
CGGCGATATGACGGGTTTTGCGGCGGCTACTTATCAACGCGGCGCGCCATTTGTTCAAATTCCCACTACTTTATTAAGTC
AGGTCGATTCCTCCGTCGGCGGCAAAACCGCCATCAACCACCCGCTCGGCAAAAATATGATCGGCGCGTTCTACCAGCCG
CAGGCGGTGCTTGCCGACTTGGACACGCTGCACACCCTGCCCGCCCGCGAACTGTCCGCCGGTATGGCGGAAGTCATCAA
ATACGGCACGCTCGGCGACATTAGTTTTTTTGAATGGCTGGAACAGCATATGCCCGAACTGATGGCACTCGAACGCGCGC
CCCTCATCCAAGCCGTGTACCGCTGTTGCCAAATGAAGGCAGACATCGTCGCCCAAGACGAAACCGAACAGGGCATACGC
GCATGGCTCAACCTCGGACACACCTTCGGACACGCCATTGAAACCGAGATGGGTTACGGTACTTGGCTGCACGGCGAGGC
CGTCGCCGCCGGCTGCGTGTTGGCGGCGCGTTTGTCCGAACAACTGGGCAAAATCTCCGCCGCAGATACCGCGCGGCTCG
CCGCCCTGCTCGAAGCCGCCGGACTGCCGTCCGCGCCACCCGTGTTTGCCTTTGAAAAATGGCTGGAACACATGAGCCAC
GATAAAAAAGTCAGTAGCGGCGTGATGCGCTTTATCGGGTTGAACCGTCTGGGCGAAGCCGTCATCACCGAAATTACCGA
CACGGACATTCTCCGCCGCACCCTGCAACCGTATCTCTGA

Upstream 100 bases:

>100_bases
CTCAAACGCTTATCCCGATAAACCGGCATATGCGCCGCGCCCAGAAAACCAAACCGCGCCCCGCCCGGCGGGCCGGCGGT
TCAAACTTTAAGGAACAACA

Downstream 100 bases:

>100_bases
TTTCCTCTGCCGATGTGCTGCCGCGCGGGTTTGACGCACGATGATGATTTTCCATCATCTTTCTCCGTAAAAGCGGGAAT
CCGGTCCGTTCGGTTTCGGT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQT
LNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQP
QAVLADLDTLHTLPARELSAGMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIR
AWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSH
DKKVSSGVMRFIGLNRLGEAVITEITDTDILRRTLQPYL

Sequences:

>Translated_359_residues
MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQT
LNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQP
QAVLADLDTLHTLPARELSAGMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIR
AWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSH
DKKVSSGVMRFIGLNRLGEAVITEITDTDILRRTLQPYL
>Mature_359_residues
MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQT
LNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQP
QAVLADLDTLHTLPARELSAGMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIR
AWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSH
DKKVSSGVMRFIGLNRLGEAVITEITDTDILRRTLQPYL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=333, Percent_Identity=57.0570570570571, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320332, Length=290, Percent_Identity=38.6206896551724, Blast_Score=189, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38773; Mature: 38773

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAA
CCEEEEECCCCCCCEEECCCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
GVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQR
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHC
GAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
GMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHEECCCHHHHHH
AWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAA
HHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GLPSAPPVFAFEKWLEHMSHDKKVSSGVMRFIGLNRLGEAVITEITDTDILRRTLQPYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
>Mature Secondary Structure
MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAA
CCEEEEECCCCCCCEEECCCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
GVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMTGFAAATYQR
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHC
GAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
GMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHEECCCHHHHHH
AWLNLGHTFGHAIETEMGYGTWLHGEAVAAGCVLAARLSEQLGKISAADTARLAALLEAA
HHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GLPSAPPVFAFEKWLEHMSHDKKVSSGVMRFIGLNRLGEAVITEITDTDILRRTLQPYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA