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The map label for this gene is oxaA [H]

Identifier: 161869308

GI number: 161869308

Start: 318333

End: 319970

Strand: Reverse

Name: oxaA [H]

Synonym: NMCC_0313

Alternate gene names: 161869308

Gene position: 319970-318333 (Counterclockwise)

Preceding gene: 161869309

Following gene: 161869305

Centisome position: 14.86

GC content: 54.95

Gene sequence:

>1638_bases
ATGGATTTTAAAAGACTCACGGCGTTTTTCGCCATCGCACTGGTGATTATGATCGGATGGGAAAAGATGTTCCCCACTCC
GAAGCCCGTCCCCGCGCCCCAACAGACGGCACAACAACAGGCCGTAACCGCTTCCGCCGAAGCCGCGCTCGCGCCCGCAA
CGCCGATTACCGTAACGACCGACACGGTTCAAGCCGTCATTGATGAAAAAAGCGGCGACCTGCGCCGGCTGACCCTGCTC
AAATACAAAGCAACCGGCGACGAAAATAAACCGTTCATCCTGTTTGGCGACGGCAAAGAATACACCTACGTCGCCCAATC
CGAACTTTTGGACGCGCAGGGCAACAACATTCTAAAAGGCATCGGCTTTAGCGCACCGAAAAAACAGTACAGCTTGGAAG
GCGACAAAGTTGAAGTCCGCCTGAGCGCACCTGAAACACGCGGTCTGAAAATCGACAAAGTTTATACTTTCACCAAAGGC
AGCTATCTGGTCAACGTCCGCTTCGACATCGCCAACGGCAGCGGTCAAACCGCCAACCTGAGCGCGGACTACCGCATCGT
CCGCGACCACAGCGAACCCGAGGGTCAAGGCTACTTTACCCACTCTTACGTCGGCCCTGTTGTTTATACCCCTGAAGGCA
ACTTCCAAAAAGTCAGCTTCTCCGACTTGGACGACGATGCCAAATCCGGCAAATCCGAGGCCGAATACATCCGCAAAACC
CCGACCGGCTGGCTCGGCATGATTGAACACCACTTCATGTCCACCTGGATCCTCCAACCCAAAGGCGGACAAAGCGTTTG
CGCCGCTGGCGACTGCCGTATCGACATCAAACGCCGCAACGACAAGCTGTACAGCACCAGCGTCAGCGTGCCTTTAGCCG
CTATCCAAAACGGCGCGAAATCCGAAGCCTCCATCAACCTCTACGCCGGCCCACAGACCACATCCGTTATCGCAAACATC
GCCGACAACCTGCAACTGGCCAAAGACTACGGCAAAGTACACTGGTTCGCCTCCCCCCTCTTTTGGCTTTTGAACCAACT
GCACAACATCATCGGCAACTGGGGCTGGGCGATTATCGTTTTAACCATCATCGTCAAAGCCGTACTGTATCCATTGACCA
ACGCCTCTTACCGCTCTATGGCGAAAATGCGTGCCGCCGCACCCAAACTGCAAGCCATCAAAGAGAAATACGGCGACGAC
CGTATGGCGCAACAACAGGCGATGATGCAGCTTTACACAGACGAGAAAATCAACCCGCTGGGCGGCTGCCTGCCTATGCT
GTTGCAAATCCCCGTCTTCATCGGATTGTATTGGGCATTGTTCGCCTCCGTAGAATTGCGCCAGGCACCTTGGCTGGGTT
GGATTACCGACCTCAGCCGCGCCGACCCCTACTACATCCTGCCCATCATTATGGCGGCAACGATGTTCGCCCAAACTTAT
CTGAACCCGCCGCCGACCGACCCGATGCAGGCGAAAATGATGAAAATCATGCCGTTGGTTTTCTCCGTCATGTTCTTCTT
CTTCCCTGCCGGTCTGGTATTGTACTGGGTAGTCAACAACCTCCTGACCATCGCCCAGCAATGGCACATCAACCGCAGCA
TCGAAAAACAACGCGCCCAAGGCGAAGTCGTTTCCTAA

Upstream 100 bases:

>100_bases
TTCGGGCTGGCGGCACGACCGTCGGGTATGAAGCCCGCCCTTATTCCCCGTCTATCGGAACACGCAACCTGCGGCATTTC
CGACCATTCAGGAAACTCTT

Downstream 100 bases:

>100_bases
ATGCCGCAGCATGAAAAATGCCGTCTGAAACCTGTTCAGACGGCATTTTTATTGTTCACCCCCTATCGGGGCGGAAATCT
TCAACCTGCATACATCACAA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTASAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLL
KYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKG
SYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKT
PTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDIKRRNDKLYSTSVSVPLAAIQNGAKSEASINLYAGPQTTSVIANI
ADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDD
RMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTY
LNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQGEVVS

Sequences:

>Translated_545_residues
MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTASAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLL
KYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKG
SYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKT
PTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDIKRRNDKLYSTSVSVPLAAIQNGAKSEASINLYAGPQTTSVIANI
ADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDD
RMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTY
LNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQGEVVS
>Mature_545_residues
MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTASAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLL
KYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKG
SYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKT
PTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDIKRRNDKLYSTSVSVPLAAIQNGAKSEASINLYAGPQTTSVIANI
ADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDD
RMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTY
LNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQGEVVS

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=202, Percent_Identity=27.7227722772277, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790140, Length=520, Percent_Identity=35.1923076923077, Blast_Score=323, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24662345, Length=211, Percent_Identity=27.9620853080569, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356443, Length=211, Percent_Identity=27.9620853080569, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 60699; Mature: 60699

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTASAEAALAPATPITVTT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEH
DTVQAVIDEKSGDLRRLTLLKYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKG
HHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCEEEEEHHHHHHCCCCCEEEC
IGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKGSYLVNVRFDIANGSGQTANL
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCEEEEEEEEEECCCCCEEEC
SADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKT
CCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCEEEEECCCCCCHHHCCCHHHHHHHCC
PTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDIKRRNDKLYSTSVSVPLAAIQNGAK
CCHHHHHHHHHHHHEEEECCCCCCCEEECCCEEEEEEECCCEEEEEECCCCHHHHCCCCC
SEASINLYAGPQTTSVIANIADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIV
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCHHHHHH
LTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDDRMAQQQAMMQLYTDEKINPL
HHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHH
GGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GEVVS
CCCCC
>Mature Secondary Structure
MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTASAEAALAPATPITVTT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEH
DTVQAVIDEKSGDLRRLTLLKYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKG
HHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCEEEEEHHHHHHCCCCCEEEC
IGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKGSYLVNVRFDIANGSGQTANL
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCEEEEEEEEEECCCCCEEEC
SADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKT
CCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCEEEEECCCCCCHHHCCCHHHHHHHCC
PTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDIKRRNDKLYSTSVSVPLAAIQNGAK
CCHHHHHHHHHHHHEEEECCCCCCCEEECCCEEEEEEECCCEEEEEECCCCHHHHCCCCC
SEASINLYAGPQTTSVIANIADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIV
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCHHHHHH
LTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDDRMAQQQAMMQLYTDEKINPL
HHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHH
GGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GEVVS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA